𝕏

Task 55398750

Name HuVeMOp_20240630064831733006_ORdGradInc_k_25-Pueyo_APDR-conf_334_0
Workunit 26306324
Created 30 Jun 2024, 4:49:50 UTC
Sent 30 Jun 2024, 7:07:28 UTC
Report deadline 3 Jul 2024, 16:43:28 UTC
Received 1 Jul 2024, 10:06:00 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 238614
Run time 2 hours 35 min 44 sec
CPU time 2 hours 35 min 16 sec
Validate state Valid
Credit 62.66
Device peak FLOPS 3.71 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.94 MB
Peak swap size 3.82 MB
Peak disk usage 0.30 MB

Stderr output

<core_client_version>7.14.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064831733006_ORdGradInc_k_25-Pueyo_APDR-conf_334.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064831733006_ORdGradInc_k_25-Pueyo_APDR-conf_334_0_r1502582887_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064831733006_ORdGradInc_k_25-Pueyo_APDR-conf_334_0_r1502582887_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 91.917207
     * GNaL_b in INaL: 0.007393
     * Gto_b in Ito: 0.075138
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.029789
     * GKs_b in IKs: 0.001793
     * GK1_b in IK1: 0.149445
     * Gncx_b in INaCa_i: 0.000976
     * Pnak_b in INaK: 69.083398
     * GKb_b in IKb: 0.003764
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.023569
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11382637, states[0] = -94.820189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 23230722, states[0] = -94.645848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 34176374, states[0] = -92.427342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 47192943, states[0] = -94.510279, states[40]= 0.000000
Saving checkpoint... 
Iteration: 58989662, states[0] = -94.778339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 70219023, states[0] = -94.578323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 81039222, states[0] = 17.476577, states[40]= 0.005286
Saving checkpoint... 
Iteration: 93527891, states[0] = 21.043710, states[40]= 0.006353
Saving checkpoint... 
Iteration: 105298827, states[0] = -94.683899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 116668274, states[0] = -80.027460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 128049048, states[0] = 14.079244, states[40]= 0.005029
Saving checkpoint... 
Iteration: 140933087, states[0] = -94.751160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 153346680, states[0] = -94.716304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 165583773, states[0] = -0.931525, states[40]= 0.004101
Saving checkpoint... 
Iteration: 179781142, states[0] = -94.661687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 191977718, states[0] = -94.759257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 203360615, states[0] = -94.723073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 215336942, states[0] = -94.709380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 226562173, states[0] = 9.122092, states[40]= 0.004905
Saving checkpoint... 
Iteration: 237674639, states[0] = -88.821486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 249080869, states[0] = 0.673827, states[40]= 0.004319
Saving checkpoint... 
Iteration: 260597659, states[0] = -10.413694, states[40]= 0.002225
Saving checkpoint... 
Iteration: 271846357, states[0] = -94.714993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 283317802, states[0] = -94.695619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 296625908, states[0] = -34.411823, states[40]= 0.000324
Saving checkpoint... 
Iteration: 310576047, states[0] = 3.099118, states[40]= 0.004573
Saving checkpoint... 
Iteration: 323196409, states[0] = -94.502872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 334554400, states[0] = 12.128934, states[40]= 0.004976
Saving checkpoint... 
Iteration: 346117777, states[0] = -27.428776, states[40]= 0.000685
Saving checkpoint... 
Iteration: 357132963, states[0] = -40.681410, states[40]= 0.000134
Saving checkpoint... 
Iteration: 368831088, states[0] = -94.705225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 380615900, states[0] = -25.832390, states[40]= 0.000766
Saving checkpoint... 
Iteration: 393737301, states[0] = -94.599287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 405097748, states[0] = -10.483251, states[40]= 0.002212
Saving checkpoint... 
Iteration: 417039719, states[0] = 17.413683, states[40]= 0.005263
Saving checkpoint... 
Iteration: 428631138, states[0] = -39.027373, states[40]= 0.000171
Saving checkpoint... 
Iteration: 441071770, states[0] = 5.079960, states[40]= 0.004722
Saving checkpoint... 
Iteration: 454357230, states[0] = -94.720898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 465448706, states[0] = -94.753124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 476472139, states[0] = -94.757762, states[40]= 0.000000
Saving checkpoint... 
Iteration: 487687507, states[0] = -94.294509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 499047856, states[0] = 14.543943, states[40]= 0.005045
Saving checkpoint... 
Iteration: 511176753, states[0] = -90.900352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 522447542, states[0] = -94.752827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 534423483, states[0] = -94.746773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 551437072, states[0] = -94.750345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 563424695, states[0] = -94.747092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 574182007, states[0] = -93.546116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 585285745, states[0] = -94.665976, states[40]= 0.000000
Saving checkpoint... 
Iteration: 596925296, states[0] = -94.747236, states[40]= 0.000000
Saving checkpoint... 
Iteration: 608198690, states[0] = -94.515335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 619284773, states[0] = -94.664904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 630408532, states[0] = -94.742195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 641593074, states[0] = -6.893271, states[40]= 0.002967
Saving checkpoint... 
Iteration: 652456414, states[0] = -94.754643, states[40]= 0.000000
Saving checkpoint... 
Iteration: 663353953, states[0] = -94.718999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 674891471, states[0] = -94.736170, states[40]= 0.000000
Saving checkpoint... 
Iteration: 686400133, states[0] = -94.739327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 697532024, states[0] = 19.908488, states[40]= 0.005796
Saving checkpoint... 
Iteration: 708496208, states[0] = -94.761402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 719689712, states[0] = -94.394333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 730963873, states[0] = -94.756071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 741830678, states[0] = -94.704693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 752687187, states[0] = -94.274261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 763580540, states[0] = 0.848714, states[40]= 0.004340
Saving checkpoint... 
Iteration: 775027073, states[0] = 21.324405, states[40]= 0.006516
Saving checkpoint... 
Iteration: 785938045, states[0] = -94.750427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 798939615, states[0] = -94.750800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 810965807, states[0] = -94.756384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 822166317, states[0] = -76.743913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 833654058, states[0] = -61.604235, states[40]= 0.000004
Saving checkpoint... 
Iteration: 844878563, states[0] = -94.730828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 856000075, states[0] = -85.518045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 867070614, states[0] = 5.593447, states[40]= 0.004753
Saving checkpoint... 
Iteration: 877805757, states[0] = -94.685238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 889855212, states[0] = -94.719530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 903116622, states[0] = -26.445670, states[40]= 0.000736
Saving checkpoint... 
Iteration: 919317871, states[0] = -94.695223, states[40]= 0.000000
Saving checkpoint... 
Iteration: 930730853, states[0] = -94.587533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 944250719, states[0] = -94.620659, states[40]= 0.000000
Saving checkpoint... 
Iteration: 955827497, states[0] = -94.702337, states[40]= 0.000000
Saving checkpoint... 
Iteration: 969208461, states[0] = -94.543385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 980814344, states[0] = -94.692391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 991584054, states[0] = -1.070717, states[40]= 0.004079
Saving checkpoint... 
Iteration: 1002671424, states[0] = -84.508095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1014276778, states[0] = -94.655609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1027633062, states[0] = -40.771374, states[40]= 0.000133
Saving checkpoint... 
Iteration: 1040717862, states[0] = -94.562768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1053440875, states[0] = -94.750932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1064943186, states[0] = -94.751470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1076652074, states[0] = -59.503093, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1092720453, states[0] = -94.567832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1105825764, states[0] = -94.701001, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1118881183, states[0] = -94.731759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1132463700, states[0] = -94.755770, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1146510522, states[0] = 24.672862, states[40]= 0.044577
Saving checkpoint... 
Iteration: 1157457724, states[0] = -94.754574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1169567318, states[0] = 7.014095, states[40]= 0.004827
Saving checkpoint... 
Iteration: 1182354187, states[0] = -94.718779, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1195300919, states[0] = -94.680675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1206757136, states[0] = -94.629953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1218735375, states[0] = -94.595392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1231281021, states[0] = -94.660347, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1243789525, states[0] = -94.669517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1255884700, states[0] = -94.733120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1269523018, states[0] = 22.328901, states[40]= 0.007695
Saving checkpoint... 
Iteration: 1282114401, states[0] = -24.559000, states[40]= 0.000824
Saving checkpoint... 
Iteration: 1293333414, states[0] = -94.706173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1303953764, states[0] = -94.753657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1315439351, states[0] = -94.750392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1329498764, states[0] = -94.761341, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1341541046, states[0] = 16.958464, states[40]= 0.005210
Saving checkpoint... 
Iteration: 1353529394, states[0] = 20.683806, states[40]= 0.006119
Saving checkpoint... 
Iteration: 1367596828, states[0] = -9.748920, states[40]= 0.002359
Saving checkpoint... 
Iteration: 1378850824, states[0] = -94.716787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1390559668, states[0] = 10.113323, states[40]= 0.004932
Saving checkpoint... 
Iteration: 1401316030, states[0] = -94.693456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1414449327, states[0] = -94.752627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1426845145, states[0] = -94.713472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1438110288, states[0] = -21.064536, states[40]= 0.000970
Saving checkpoint... 
Iteration: 1450833229, states[0] = -94.705944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1463075078, states[0] = 3.560618, states[40]= 0.004612
Saving checkpoint... 
Iteration: 1474257708, states[0] = -94.630590, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1487319179, states[0] = -94.695853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1497907506, states[0] = -94.741282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1511548986, states[0] = -84.531660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1522361929, states[0] = -94.445475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1533749209, states[0] = -87.075536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1545254390, states[0] = -95.003913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1556823818, states[0] = -53.566786, states[40]= 0.000019
Saving checkpoint... 
Iteration: 1568815541, states[0] = -44.663649, states[40]= 0.000075
Saving checkpoint... 
Iteration: 1580508181, states[0] = -37.184046, states[40]= 0.000220
Saving checkpoint... 
Iteration: 1591645503, states[0] = -83.344055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1602640479, states[0] = 14.309870, states[40]= 0.006111
Saving checkpoint... 
Iteration: 1616268269, states[0] = -94.820332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1628653548, states[0] = -95.020240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1640322829, states[0] = -94.975385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1651761662, states[0] = -95.030511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1664117531, states[0] = 23.148398, states[40]= 0.013763
Saving checkpoint... 
Iteration: 1675255267, states[0] = 7.036723, states[40]= 0.005540
Saving checkpoint... 
Iteration: 1688135210, states[0] = 16.641406, states[40]= 0.006477
Saving checkpoint... 
Iteration: 1699672119, states[0] = -94.853149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1711031536, states[0] = -63.338085, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1722798793, states[0] = -94.928739, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1733786283, states[0] = -15.823475, states[40]= 0.001530
Saving checkpoint... 
Iteration: 1744965353, states[0] = -94.775663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1757069548, states[0] = -95.039568, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1768388564, states[0] = -94.904898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1780079201, states[0] = -94.880238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1792136027, states[0] = -94.997454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1802976911, states[0] = -94.818842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1814109591, states[0] = -22.845753, states[40]= 0.000907
Saving checkpoint... 
Iteration: 1826502941, states[0] = 37.463480, states[40]= 0.151810
Saving checkpoint... 
Iteration: 1841681375, states[0] = -93.775284, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1852782776, states[0] = -94.677826, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1864031905, states[0] = 19.827092, states[40]= 0.005802
Saving checkpoint... 
Iteration: 1875125534, states[0] = -34.499141, states[40]= 0.000320
Saving checkpoint... 
Iteration: 1886080830, states[0] = 0.550478, states[40]= 0.004310
Saving checkpoint... 
Iteration: 1897656244, states[0] = -64.297674, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1909332876, states[0] = -94.708342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1922167219, states[0] = -78.297537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1934715388, states[0] = -94.558582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1946899622, states[0] = -94.739238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1958147117, states[0] = -54.453817, states[40]= 0.000015
Saving checkpoint... 
Iteration: 1969347193, states[0] = -94.714769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1980886611, states[0] = -94.733711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1991962900, states[0] = -94.755247, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2004252597, states[0] = -94.622907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2016884735, states[0] = -94.732694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2028326114, states[0] = -94.700667, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2039601398, states[0] = -13.493128, states[40]= 0.001678
Saving checkpoint... 
Iteration: 2050473262, states[0] = -94.756898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2062124660, states[0] = -33.329438, states[40]= 0.000372
Saving checkpoint... 
Iteration: 2073811476, states[0] = -94.689281, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2084767722, states[0] = -94.643700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2095742888, states[0] = -94.607472, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.636823
 - CaMKt in component CaMK (millimolar): 0.007252
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.657866
 - nass in component intracellular_ions (millimolar): 6.657925
 - ki in component intracellular_ions (millimolar): 145.316915
 - kss in component intracellular_ions (millimolar): 145.316897
 - cansr in component intracellular_ions (millimolar): 1.324279
 - cajsr in component intracellular_ions (millimolar): 1.285057
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003717
 - hf in component INa (dimensionless): 0.875326
 - hs in component INa (dimensionless): 0.875320
 - j in component INa (dimensionless): 0.875285
 - hsp in component INa (dimensionless): 0.717075
 - jp in component INa (dimensionless): 0.875261
 - mL in component INaL (dimensionless): 0.000052
 - hL in component INaL (dimensionless): 0.699401
 - hLp in component INaL (dimensionless): 0.434259
 - a in component Ito (dimensionless): 0.000635
 - iF in component Ito (dimensionless): 0.999863
 - iS in component Ito (dimensionless): 0.606501
 - ap in component Ito (dimensionless): 0.000323
 - iFp in component Ito (dimensionless): 0.999863
 - iSp in component Ito (dimensionless): 0.677919
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.925569
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999848
 - jca in component ICaL (dimensionless): 0.999972
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001659
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.353096
 - xs1 in component IKs (dimensionless): 0.260035
 - xs2 in component IKs (dimensionless): 0.000090
 - xk1 in component IK1 (dimensionless): 0.997406
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
11:56:57 (93574): called boinc_finish(0)

</stderr_txt>
]]>


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