𝕏

Task 55398749

Name HuVeMOp_20240630064831733006_ORdGradInc_k_25-Pueyo_APDR-conf_234_1
Workunit 26306323
Created 30 Jun 2024, 4:49:50 UTC
Sent 30 Jun 2024, 7:07:28 UTC
Report deadline 3 Jul 2024, 16:43:28 UTC
Received 1 Jul 2024, 10:06:00 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 238614
Run time 2 hours 32 min 48 sec
CPU time 2 hours 32 min 28 sec
Validate state Valid
Credit 59.46
Device peak FLOPS 3.71 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.93 MB
Peak swap size 3.82 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.14.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064831733006_ORdGradInc_k_25-Pueyo_APDR-conf_234.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064831733006_ORdGradInc_k_25-Pueyo_APDR-conf_234_1_r226669402_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064831733006_ORdGradInc_k_25-Pueyo_APDR-conf_234_1_r226669402_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 113.199340
     * GNaL_b in INaL: 0.004468
     * Gto_b in Ito: 0.085985
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.031035
     * GKs_b in IKs: 0.002029
     * GK1_b in IK1: 0.178108
     * Gncx_b in INaCa_i: 0.000961
     * Pnak_b in INaK: 68.371596
     * GKb_b in IKb: 0.003715
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.027205
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11564259, states[0] = 2.592187, states[40]= 0.004568
Saving checkpoint... 
Iteration: 22503191, states[0] = 36.016130, states[40]= 0.143922
Saving checkpoint... 
Iteration: 34684209, states[0] = -94.808498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 49700547, states[0] = -94.830598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 67386902, states[0] = -94.986233, states[40]= 0.000000
Saving checkpoint... 
Iteration: 80858517, states[0] = -94.973168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 95351064, states[0] = -94.967894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 107283022, states[0] = -94.925091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 118391006, states[0] = -94.980242, states[40]= 0.000000
Saving checkpoint... 
Iteration: 130280711, states[0] = -94.921695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 142615504, states[0] = -38.458640, states[40]= 0.000159
Saving checkpoint... 
Iteration: 154957512, states[0] = -94.993583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 167718125, states[0] = -94.845324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 180198453, states[0] = -94.810393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 192326208, states[0] = -94.951902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 205182071, states[0] = -94.776611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 216993385, states[0] = -94.997833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 229548408, states[0] = 10.891591, states[40]= 0.005053
Saving checkpoint... 
Iteration: 241822195, states[0] = -94.949444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 253401883, states[0] = -94.981206, states[40]= 0.000000
Saving checkpoint... 
Iteration: 266174726, states[0] = -94.752257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 278558064, states[0] = 6.844062, states[40]= 0.004881
Saving checkpoint... 
Iteration: 290723583, states[0] = -94.853368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 302502964, states[0] = 37.791536, states[40]= 0.135112
Saving checkpoint... 
Iteration: 315050166, states[0] = 10.182488, states[40]= 0.005019
Saving checkpoint... 
Iteration: 326674514, states[0] = -94.751018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 338808791, states[0] = -94.941162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 350039113, states[0] = 14.488944, states[40]= 0.005361
Saving checkpoint... 
Iteration: 362372587, states[0] = -94.972072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 375175573, states[0] = -94.756347, states[40]= 0.000000
Saving checkpoint... 
Iteration: 387764410, states[0] = -94.904785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 399717119, states[0] = -94.843033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 412032493, states[0] = 16.833454, states[40]= 0.005853
Saving checkpoint... 
Iteration: 424335373, states[0] = -94.956319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 436105124, states[0] = -28.344712, states[40]= 0.000538
Saving checkpoint... 
Iteration: 447172714, states[0] = -94.738344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 458160650, states[0] = -93.605989, states[40]= 0.000000
Saving checkpoint... 
Iteration: 470801954, states[0] = -94.936471, states[40]= 0.000000
Saving checkpoint... 
Iteration: 483119548, states[0] = -42.404380, states[40]= 0.000089
Saving checkpoint... 
Iteration: 495432306, states[0] = -94.988110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 507174231, states[0] = -94.749244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 519338614, states[0] = -94.957856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 530915179, states[0] = -94.984334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 545049482, states[0] = 10.460351, states[40]= 0.005032
Saving checkpoint... 
Iteration: 557963716, states[0] = -94.993580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 568295458, states[0] = -94.931736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 578446313, states[0] = -94.990711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 588472333, states[0] = -94.994810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 598581581, states[0] = -6.522690, states[40]= 0.003126
Saving checkpoint... 
Iteration: 609232851, states[0] = -94.866760, states[40]= 0.000000
Saving checkpoint... 
Iteration: 619386401, states[0] = -94.976462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 630824674, states[0] = -94.950526, states[40]= 0.000000
Saving checkpoint... 
Iteration: 641480361, states[0] = -94.995853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 655697926, states[0] = -94.808718, states[40]= 0.000000
Saving checkpoint... 
Iteration: 666671178, states[0] = -94.721732, states[40]= 0.000000
Saving checkpoint... 
Iteration: 678080389, states[0] = -5.606806, states[40]= 0.003322
Saving checkpoint... 
Iteration: 688228922, states[0] = -94.861086, states[40]= 0.000000
Saving checkpoint... 
Iteration: 698918676, states[0] = -94.985038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 710245485, states[0] = -94.883332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 721733128, states[0] = -94.867072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 733065615, states[0] = 3.325361, states[40]= 0.004667
Saving checkpoint... 
Iteration: 744454876, states[0] = -94.992064, states[40]= 0.000000
Saving checkpoint... 
Iteration: 755498015, states[0] = -94.997880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 766481189, states[0] = -94.995877, states[40]= 0.000000
Saving checkpoint... 
Iteration: 777033781, states[0] = 16.397346, states[40]= 0.005728
Saving checkpoint... 
Iteration: 787139606, states[0] = -64.295455, states[40]= 0.000002
Saving checkpoint... 
Iteration: 797889590, states[0] = -94.977316, states[40]= 0.000000
Saving checkpoint... 
Iteration: 808792458, states[0] = -94.929315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 819814237, states[0] = -94.944286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 830989562, states[0] = -94.996867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 842451630, states[0] = -94.991458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 853909134, states[0] = -94.982647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 864615380, states[0] = -38.260892, states[40]= 0.000163
Saving checkpoint... 
Iteration: 875843218, states[0] = -94.959809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 887216985, states[0] = -94.842488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 898796270, states[0] = -94.932117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 910137910, states[0] = -62.219039, states[40]= 0.000003
Saving checkpoint... 
Iteration: 920689435, states[0] = -94.791759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 931566197, states[0] = 3.034817, states[40]= 0.004643
Saving checkpoint... 
Iteration: 942423764, states[0] = -94.986016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 953395171, states[0] = -94.978846, states[40]= 0.000000
Saving checkpoint... 
Iteration: 963853567, states[0] = -94.964335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 975024669, states[0] = 19.210616, states[40]= 0.007284
Saving checkpoint... 
Iteration: 986662395, states[0] = -94.099545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 998589875, states[0] = -13.747511, states[40]= 0.001679
Saving checkpoint... 
Iteration: 1009587056, states[0] = -11.152412, states[40]= 0.002143
Saving checkpoint... 
Iteration: 1021362752, states[0] = -94.968004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1036366412, states[0] = -94.969384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1051588606, states[0] = -12.566587, states[40]= 0.001879
Saving checkpoint... 
Iteration: 1062576773, states[0] = -3.039429, states[40]= 0.003833
Saving checkpoint... 
Iteration: 1075082454, states[0] = -7.215361, states[40]= 0.002975
Saving checkpoint... 
Iteration: 1086130814, states[0] = -54.191265, states[40]= 0.000014
Saving checkpoint... 
Iteration: 1101640609, states[0] = -65.568946, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1113199709, states[0] = -94.811811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1124317118, states[0] = -94.945835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1135219417, states[0] = -94.846257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1146344003, states[0] = -94.959993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1157091576, states[0] = -15.353800, states[40]= 0.001442
Saving checkpoint... 
Iteration: 1169323291, states[0] = -94.949394, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1180513352, states[0] = 21.710153, states[40]= 0.025706
Saving checkpoint... 
Iteration: 1191806353, states[0] = -94.938986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1202633368, states[0] = -56.994876, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1214475630, states[0] = -94.994848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1226388777, states[0] = -94.976787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1238410304, states[0] = -94.982683, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1249904563, states[0] = -94.981214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1262325777, states[0] = -94.950717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1274466700, states[0] = -94.993549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1284964420, states[0] = -94.993203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1296495775, states[0] = -94.997273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1307630728, states[0] = -54.097741, states[40]= 0.000014
Saving checkpoint... 
Iteration: 1319049322, states[0] = 10.525270, states[40]= 0.005035
Saving checkpoint... 
Iteration: 1330686342, states[0] = -94.785084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1342234023, states[0] = -94.867905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1354246026, states[0] = -94.883569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1366292814, states[0] = -94.929216, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1380413450, states[0] = -94.983358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1397182664, states[0] = -94.777015, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1410848239, states[0] = -94.961735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1423420662, states[0] = -94.985009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1434675931, states[0] = -94.757212, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1445856074, states[0] = -94.965059, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1457989328, states[0] = -94.996423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1469051189, states[0] = 9.764632, states[40]= 0.005001
Saving checkpoint... 
Iteration: 1480063100, states[0] = 4.545467, states[40]= 0.004756
Saving checkpoint... 
Iteration: 1492043478, states[0] = 12.834289, states[40]= 0.005180
Saving checkpoint... 
Iteration: 1503573261, states[0] = -95.184980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1514775008, states[0] = -11.680071, states[40]= 0.002267
Saving checkpoint... 
Iteration: 1527140364, states[0] = -93.932822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1541420247, states[0] = 20.225439, states[40]= 0.011067
Saving checkpoint... 
Iteration: 1557300225, states[0] = -67.612742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1568961250, states[0] = -95.214996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1582944985, states[0] = -94.891416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1598628877, states[0] = -95.185341, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1615559317, states[0] = 0.414164, states[40]= 0.004903
Saving checkpoint... 
Iteration: 1634139287, states[0] = 11.927129, states[40]= 0.006166
Saving checkpoint... 
Iteration: 1647077546, states[0] = -16.573103, states[40]= 0.001435
Saving checkpoint... 
Iteration: 1659167743, states[0] = -95.079259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1670819273, states[0] = -65.455134, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1686614466, states[0] = 21.860729, states[40]= 0.022458
Saving checkpoint... 
Iteration: 1701718717, states[0] = -64.685886, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1714759438, states[0] = -95.220193, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1726203534, states[0] = 35.528567, states[40]= 0.123043
Saving checkpoint... 
Iteration: 1738716216, states[0] = -95.170967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1750296590, states[0] = -37.801839, states[40]= 0.000176
Saving checkpoint... 
Iteration: 1761696947, states[0] = -38.202628, states[40]= 0.000166
Saving checkpoint... 
Iteration: 1773305189, states[0] = 29.203711, states[40]= 0.129912
Saving checkpoint... 
Iteration: 1787708189, states[0] = 24.657137, states[40]= 0.080037
Saving checkpoint... 
Iteration: 1804080648, states[0] = -8.577960, states[40]= 0.002767
Saving checkpoint... 
Iteration: 1816254865, states[0] = -94.927929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1829411127, states[0] = -95.006833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1841556871, states[0] = 6.967989, states[40]= 0.004900
Saving checkpoint... 
Iteration: 1853325670, states[0] = -94.962431, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1865026358, states[0] = 18.633134, states[40]= 0.006802
Saving checkpoint... 
Iteration: 1880412076, states[0] = -94.988101, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1893665055, states[0] = -94.510759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1904768382, states[0] = -94.910395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1920427209, states[0] = -94.987740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1935807707, states[0] = -94.940418, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1948061111, states[0] = 5.454986, states[40]= 0.004811
Saving checkpoint... 
Iteration: 1959336716, states[0] = -94.956456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1970453417, states[0] = -94.991345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1981913024, states[0] = -94.983080, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1994661907, states[0] = -93.990410, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2006270154, states[0] = -94.909464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2019173226, states[0] = -94.741510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2030914212, states[0] = -94.983121, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2042067198, states[0] = 2.525831, states[40]= 0.004598
Saving checkpoint... 
Iteration: 2053147377, states[0] = -75.539965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2065149631, states[0] = -79.531297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2076125735, states[0] = -48.772949, states[40]= 0.000033
Saving checkpoint... 
Iteration: 2087143300, states[0] = -69.205094, states[40]= 0.000001
Saving checkpoint... 
Iteration: 2097948091, states[0] = -94.989972, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.873034
 - CaMKt in component CaMK (millimolar): 0.007022
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.682277
 - nass in component intracellular_ions (millimolar): 6.682337
 - ki in component intracellular_ions (millimolar): 145.292656
 - kss in component intracellular_ions (millimolar): 145.292638
 - cansr in component intracellular_ions (millimolar): 1.323116
 - cajsr in component intracellular_ions (millimolar): 1.285627
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003629
 - hf in component INa (dimensionless): 0.879500
 - hs in component INa (dimensionless): 0.879496
 - j in component INa (dimensionless): 0.879469
 - hsp in component INa (dimensionless): 0.724889
 - jp in component INa (dimensionless): 0.879451
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.710298
 - hLp in component INaL (dimensionless): 0.454637
 - a in component Ito (dimensionless): 0.000625
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.625928
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.702068
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.940025
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999899
 - jca in component ICaL (dimensionless): 0.999980
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001654
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.326550
 - xs1 in component IKs (dimensionless): 0.231528
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997345
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
11:46:27 (93564): called boinc_finish(0)

</stderr_txt>
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