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Task 55398446

Name HuVeMOp_20240630064831733006_ORdGradInc_k_25-BASE_MID-conf_831_0
Workunit 26306172
Created 30 Jun 2024, 4:49:37 UTC
Sent 30 Jun 2024, 7:05:34 UTC
Report deadline 3 Jul 2024, 7:05:34 UTC
Received 30 Jun 2024, 16:27:40 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 235508
Run time 1 hours 22 min 31 sec
CPU time 55 min 47 sec
Validate state Invalid
Credit 0.00
Device peak FLOPS 4.22 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 3.08 MB
Peak swap size 391.82 GB
Peak disk usage 0.33 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064831733006_ORdGradInc_k_25-BASE_MID-conf_831.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064831733006_ORdGradInc_k_25-BASE_MID-conf_831_0_r567693401_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064831733006_ORdGradInc_k_25-BASE_MID-conf_831_0_r567693401_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 14
     * GNa in INa: 106.442733
     * GNaL_b in INaL: 0.005289
     * Gto_b in Ito: 0.089998
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.032330
     * GKs_b in IKs: 0.001768
     * GK1_b in IK1: 0.146375
     * Gncx_b in INaCa_i: 0.000958
     * Pnak_b in INaK: 66.960368
     * GKb_b in IKb: 0.003722
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.025838
     * celltype in environment: 2.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 22426034, states[0] = -86.636230, states[40]= 0.000002
Saving checkpoint... 
Iteration: 42373725, states[0] = -86.630767, states[40]= 0.000002
Saving checkpoint... 
Iteration: 60885062, states[0] = -86.686515, states[40]= 0.000002
Saving checkpoint... 
Iteration: 78809809, states[0] = -86.548464, states[40]= 0.000002
Saving checkpoint... 
Iteration: 97346833, states[0] = -86.661130, states[40]= 0.000002
Saving checkpoint... 
Iteration: 116743030, states[0] = -86.236909, states[40]= 0.000001
Saving checkpoint... 
Iteration: 139752014, states[0] = -86.304729, states[40]= 0.000001
Saving checkpoint... 
Iteration: 164173171, states[0] = -54.207489, states[40]= 0.000119
Saving checkpoint... 
Iteration: 189119423, states[0] = -7.202228, states[40]= 0.000304
Saving checkpoint... 
Iteration: 210926920, states[0] = -86.784130, states[40]= 0.000002
Saving checkpoint... 
Iteration: 230940986, states[0] = -86.793805, states[40]= 0.000002
Saving checkpoint... 
Iteration: 247641769, states[0] = -25.836374, states[40]= 0.000806
Saving checkpoint... 
Iteration: 263097679, states[0] = 6.489476, states[40]= 0.000072
Saving checkpoint... 
Iteration: 280962421, states[0] = -86.803939, states[40]= 0.000002
Saving checkpoint... 
Iteration: 301721133, states[0] = -86.053323, states[40]= 0.000001
Saving checkpoint... 
Iteration: 324388022, states[0] = -86.736378, states[40]= 0.000002
Saving checkpoint... 
Iteration: 349427649, states[0] = -86.775708, states[40]= 0.000002
Saving checkpoint... 
Iteration: 374035126, states[0] = 30.296039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 398951325, states[0] = -86.789195, states[40]= 0.000002
Saving checkpoint... 
Iteration: 419751830, states[0] = -86.290244, states[40]= 0.000001
Saving checkpoint... 
Iteration: 435393708, states[0] = -86.735619, states[40]= 0.000002
Saving checkpoint... 
Iteration: 448466464, states[0] = -86.794348, states[40]= 0.000002
Saving checkpoint... 
Iteration: 462618571, states[0] = -6.577598, states[40]= 0.000299
Saving checkpoint... 
Iteration: 479521242, states[0] = 31.135661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 499132864, states[0] = -18.659004, states[40]= 0.000379
Saving checkpoint... 
Iteration: 521343854, states[0] = -86.647946, states[40]= 0.000002
Saving checkpoint... 
Iteration: 545496540, states[0] = -86.800728, states[40]= 0.000002
Saving checkpoint... 
Iteration: 571971628, states[0] = -86.788296, states[40]= 0.000002
Saving checkpoint... 
Iteration: 597367431, states[0] = -86.687036, states[40]= 0.000002
Saving checkpoint... 
Iteration: 619118530, states[0] = -6.531327, states[40]= 0.000298
Saving checkpoint... 
Iteration: 637004526, states[0] = 19.490062, states[40]= -0.000000
Saving checkpoint... 
Iteration: 652170697, states[0] = -51.878648, states[40]= 0.000158
Saving checkpoint... 
Iteration: 667714247, states[0] = -85.941570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 685719301, states[0] = -86.005706, states[40]= 0.000001
Saving checkpoint... 
Iteration: 705651669, states[0] = -33.944911, states[40]= 0.000844
Saving checkpoint... 
Iteration: 728345452, states[0] = -86.636698, states[40]= 0.000002
Saving checkpoint... 
Iteration: 753366682, states[0] = -86.674749, states[40]= 0.000002
Saving checkpoint... 
Iteration: 778009494, states[0] = 26.694031, states[40]= -0.000000
Saving checkpoint... 
Iteration: 800671059, states[0] = -52.221490, states[40]= 0.000151
Saving checkpoint... 
Iteration: 820825116, states[0] = -86.581315, states[40]= 0.000002
Saving checkpoint... 
Iteration: 837889413, states[0] = -86.701811, states[40]= 0.000002
Saving checkpoint... 
Iteration: 854106090, states[0] = 1.871160, states[40]= 0.000150
Saving checkpoint... 
Iteration: 871366433, states[0] = -86.665943, states[40]= 0.000002
Saving checkpoint... 
Iteration: 891065691, states[0] = 21.135627, states[40]= 0.000002
Saving checkpoint... 
Iteration: 912978066, states[0] = -86.767357, states[40]= 0.000002
Saving checkpoint... 
Iteration: 937143492, states[0] = -27.149040, states[40]= 0.000866
Saving checkpoint... 
Iteration: 962496564, states[0] = -86.771392, states[40]= 0.000002
Saving checkpoint... 
Iteration: 987035350, states[0] = 30.275918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1008726323, states[0] = -86.050113, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1025999899, states[0] = -86.768092, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1041315776, states[0] = -86.538854, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1056551755, states[0] = 26.131183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1074672069, states[0] = -53.205685, states[40]= 0.000133
Saving checkpoint... 
Iteration: 1095386191, states[0] = -86.679465, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1117787038, states[0] = -86.429215, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1142831356, states[0] = -86.574637, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1168351581, states[0] = -86.617963, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1191105439, states[0] = 2.269626, states[40]= 0.000141
Saving checkpoint... 
Iteration: 1210180733, states[0] = -62.516767, states[40]= 0.000039
Saving checkpoint... 
Iteration: 1226252968, states[0] = -86.238985, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1241728671, states[0] = -86.053740, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1258497305, states[0] = -86.750893, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1278005588, states[0] = 22.072052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1300938930, states[0] = -86.717329, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1324726792, states[0] = -86.031082, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1347630599, states[0] = -16.649111, states[40]= 0.000327
Saving checkpoint... 
Iteration: 1370509739, states[0] = 26.904084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1390614999, states[0] = -3.827144, states[40]= 0.000261
Saving checkpoint... 
Iteration: 1408616931, states[0] = -5.238462, states[40]= 0.000281
Saving checkpoint... 
Iteration: 1427222173, states[0] = -85.980298, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1446239084, states[0] = -86.124146, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1466026971, states[0] = 31.256624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1486977717, states[0] = -86.726819, states[40]= 0.000002
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.610731
 - CaMKt in component CaMK (millimolar): 0.027092
 - cass in component intracellular_ions (millimolar): 0.000097
 - nai in component intracellular_ions (millimolar): 8.256142
 - nass in component intracellular_ions (millimolar): 8.256305
 - ki in component intracellular_ions (millimolar): 142.993433
 - kss in component intracellular_ions (millimolar): 142.993394
 - cansr in component intracellular_ions (millimolar): 2.194756
 - cajsr in component intracellular_ions (millimolar): 2.138614
 - cai in component intracellular_ions (millimolar): 0.000100
 - m in component INa (dimensionless): 0.008342
 - hf in component INa (dimensionless): 0.652514
 - hs in component INa (dimensionless): 0.652480
 - j in component INa (dimensionless): 0.652284
 - hsp in component INa (dimensionless): 0.403931
 - jp in component INa (dimensionless): 0.652141
 - mL in component INaL (dimensionless): 0.000239
 - hL in component INaL (dimensionless): 0.449089
 - hLp in component INaL (dimensionless): 0.216966
 - a in component Ito (dimensionless): 0.001090
 - iF in component Ito (dimensionless): 0.999443
 - iS in component Ito (dimensionless): 0.533123
 - ap in component Ito (dimensionless): 0.000556
 - iFp in component Ito (dimensionless): 0.999443
 - iSp in component Ito (dimensionless): 0.575923
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.878782
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999632
 - jca in component ICaL (dimensionless): 0.999942
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004521
 - xrf in component IKr (dimensionless): 0.000011
 - xrs in component IKr (dimensionless): 0.510980
 - xs1 in component IKs (dimensionless): 0.331068
 - xs2 in component IKs (dimensionless): 0.000222
 - xk1 in component IK1 (dimensionless): 0.997077
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000002
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000002
11:27:26 (37757): called boinc_finish(0)

</stderr_txt>
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