𝕏

Task 55398333

Name HuVeMOp_20240630064831733006_ORdGradInc_k_25-Pueyo_APDR-conf_229_1
Workunit 26306116
Created 30 Jun 2024, 4:49:31 UTC
Sent 30 Jun 2024, 7:05:53 UTC
Report deadline 3 Jul 2024, 16:41:53 UTC
Received 3 Jul 2024, 10:32:37 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 238379
Run time 2 hours 52 min 31 sec
CPU time 2 hours 36 min 51 sec
Validate state Valid
Credit 60.68
Device peak FLOPS 4.35 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.36 MB
Peak swap size 3.82 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>7.16.6</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064831733006_ORdGradInc_k_25-Pueyo_APDR-conf_229.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064831733006_ORdGradInc_k_25-Pueyo_APDR-conf_229_1_r2099055919_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064831733006_ORdGradInc_k_25-Pueyo_APDR-conf_229_1_r2099055919_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 95.596146
     * GNaL_b in INaL: 0.004807
     * Gto_b in Ito: 0.075556
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032435
     * GKs_b in IKs: 0.002093
     * GK1_b in IK1: 0.173271
     * Gncx_b in INaCa_i: 0.000959
     * Pnak_b in INaK: 70.660785
     * GKb_b in IKb: 0.003664
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.019840
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 13881398, states[0] = -95.092785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 27345723, states[0] = -95.048738, states[40]= 0.000000
Saving checkpoint... 
Iteration: 40889270, states[0] = -95.048906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 54798692, states[0] = -94.993515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 68722878, states[0] = -94.901556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 82126629, states[0] = -51.737074, states[40]= 0.000021
Saving checkpoint... 
Iteration: 95515411, states[0] = 22.580424, states[40]= 0.017009
Saving checkpoint... 
Iteration: 108950241, states[0] = -95.038042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 122444847, states[0] = -95.035799, states[40]= 0.000000
Saving checkpoint... 
Iteration: 135845007, states[0] = -95.003949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 149241355, states[0] = -94.917137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 162636114, states[0] = -62.054574, states[40]= 0.000004
Saving checkpoint... 
Iteration: 176033732, states[0] = 17.381642, states[40]= 0.005815
Saving checkpoint... 
Iteration: 189449749, states[0] = -95.034468, states[40]= 0.000000
Saving checkpoint... 
Iteration: 202845809, states[0] = -95.002802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 216240015, states[0] = -94.914261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 230014635, states[0] = 22.797371, states[40]= 0.019441
Saving checkpoint... 
Iteration: 243930071, states[0] = -95.030251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 257860854, states[0] = -95.009226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 271628170, states[0] = -52.775741, states[40]= 0.000018
Saving checkpoint... 
Iteration: 285054794, states[0] = 8.906997, states[40]= 0.005041
Saving checkpoint... 
Iteration: 298466386, states[0] = -95.036834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 311854578, states[0] = -95.006490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 325246570, states[0] = -94.922659, states[40]= 0.000000
Saving checkpoint... 
Iteration: 338674364, states[0] = -94.785942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 352089661, states[0] = -13.446437, states[40]= 0.001749
Saving checkpoint... 
Iteration: 365514168, states[0] = 22.900479, states[40]= 0.021150
Saving checkpoint... 
Iteration: 378937787, states[0] = -95.031702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 392341229, states[0] = -95.000211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 405730543, states[0] = -94.900439, states[40]= 0.000000
Saving checkpoint... 
Iteration: 419309737, states[0] = -94.981939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 433207465, states[0] = -94.861743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 447145409, states[0] = -75.106532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 461063437, states[0] = 4.911353, states[40]= 0.004849
Saving checkpoint... 
Iteration: 474978855, states[0] = -95.038522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 488898989, states[0] = -95.022225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 502688916, states[0] = -94.824641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 516088536, states[0] = -12.368940, states[40]= 0.001938
Saving checkpoint... 
Iteration: 529526604, states[0] = 19.770164, states[40]= 0.006820
Saving checkpoint... 
Iteration: 542932212, states[0] = -95.030438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 556337212, states[0] = -94.998070, states[40]= 0.000000
Saving checkpoint... 
Iteration: 569753035, states[0] = -94.930455, states[40]= 0.000000
Saving checkpoint... 
Iteration: 583161095, states[0] = -94.159815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 596564230, states[0] = 4.519836, states[40]= 0.004823
Saving checkpoint... 
Iteration: 609964215, states[0] = -95.036273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 623367638, states[0] = -95.011640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 636761807, states[0] = -94.940411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 650153694, states[0] = -89.337014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 663564021, states[0] = 4.623560, states[40]= 0.004830
Saving checkpoint... 
Iteration: 677447147, states[0] = -95.033310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 690909192, states[0] = -95.024898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 704675454, states[0] = -94.790322, states[40]= 0.000000
Saving checkpoint... 
Iteration: 718610429, states[0] = -34.060529, states[40]= 0.000290
Saving checkpoint... 
Iteration: 732369340, states[0] = -95.012220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 745971662, states[0] = -95.037318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 759480141, states[0] = -95.038510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 773087081, states[0] = -11.002722, states[40]= 0.002200
Saving checkpoint... 
Iteration: 786531556, states[0] = 18.155204, states[40]= 0.006034
Saving checkpoint... 
Iteration: 799932122, states[0] = -95.030249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 813347071, states[0] = -95.002749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 826746585, states[0] = -94.922337, states[40]= 0.000000
Saving checkpoint... 
Iteration: 840230847, states[0] = -94.900603, states[40]= 0.000000
Saving checkpoint... 
Iteration: 853910916, states[0] = -95.025239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 867824309, states[0] = -94.990782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 881763028, states[0] = -94.941570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 895673279, states[0] = -94.779969, states[40]= 0.000000
Saving checkpoint... 
Iteration: 909224929, states[0] = -94.891460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 922924855, states[0] = -95.028571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 936868005, states[0] = -95.011573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 950795290, states[0] = -94.971132, states[40]= 0.000000
Saving checkpoint... 
Iteration: 964729743, states[0] = -94.898863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 978649603, states[0] = -82.596858, states[40]= 0.000000
Saving checkpoint... 
Iteration: 992587471, states[0] = -11.365353, states[40]= 0.002128
Saving checkpoint... 
Iteration: 1006495244, states[0] = -95.040260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1020404810, states[0] = -95.023506, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1034150540, states[0] = -84.301044, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1047560570, states[0] = 6.287241, states[40]= 0.004928
Saving checkpoint... 
Iteration: 1060968866, states[0] = -95.036693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1074380908, states[0] = -95.016159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1088019057, states[0] = 21.815972, states[40]= 0.010623
Saving checkpoint... 
Iteration: 1101803788, states[0] = -94.977361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1115630891, states[0] = -55.839067, states[40]= 0.000011
Saving checkpoint... 
Iteration: 1129144276, states[0] = -73.251088, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1142536423, states[0] = 16.403050, states[40]= 0.005607
Saving checkpoint... 
Iteration: 1155932672, states[0] = -95.030129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1169373221, states[0] = -95.013378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1183075317, states[0] = -1.712084, states[40]= 0.004115
Saving checkpoint... 
Iteration: 1196666699, states[0] = -94.680955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1210390559, states[0] = -95.019217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1223997960, states[0] = -95.040432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1237423576, states[0] = -95.028070, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1250841072, states[0] = -94.999562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1264282684, states[0] = -94.960487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1277669284, states[0] = -94.741411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1291079806, states[0] = -4.853636, states[40]= 0.003524
Saving checkpoint... 
Iteration: 1304473882, states[0] = -95.037272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1317866372, states[0] = -95.010687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1331303508, states[0] = -94.977008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1344985235, states[0] = -95.038798, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1358884692, states[0] = -95.017239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1372538997, states[0] = 15.424753, states[40]= 0.005457
Saving checkpoint... 
Iteration: 1385921179, states[0] = -95.027415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1399336630, states[0] = -94.997210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1412730701, states[0] = -94.900002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1426122803, states[0] = -46.877534, states[40]= 0.000046
Saving checkpoint... 
Iteration: 1439508444, states[0] = 24.832728, states[40]= 0.074263
Saving checkpoint... 
Iteration: 1453089743, states[0] = -13.524669, states[40]= 0.001736
Saving checkpoint... 
Iteration: 1467003208, states[0] = 36.401126, states[40]= 0.149882
Saving checkpoint... 
Iteration: 1480913134, states[0] = -95.025390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1494816704, states[0] = -94.985757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1508297597, states[0] = -95.143214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1521595101, states[0] = -95.264130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1533001782, states[0] = 46.273372, states[40]= 0.066502
Saving checkpoint... 
Iteration: 1542722156, states[0] = -69.481817, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1552645391, states[0] = -94.939548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1562661440, states[0] = -95.260843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1572836029, states[0] = -95.236513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1582828932, states[0] = 17.668292, states[40]= 0.007416
Saving checkpoint... 
Iteration: 1592625048, states[0] = -95.225429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1602486515, states[0] = -95.160847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1612396724, states[0] = -95.181646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1622260226, states[0] = -95.099076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1632267277, states[0] = -95.273887, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1642065150, states[0] = -95.112967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1652080434, states[0] = -95.284853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1662149722, states[0] = -95.052806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1671637137, states[0] = 13.751890, states[40]= 0.006425
Saving checkpoint... 
Iteration: 1681840887, states[0] = 11.839317, states[40]= 0.006158
Saving checkpoint... 
Iteration: 1691712557, states[0] = 23.655998, states[40]= 0.030554
Saving checkpoint... 
Iteration: 1701636142, states[0] = 14.242818, states[40]= 0.006508
Saving checkpoint... 
Iteration: 1711425089, states[0] = -95.228710, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1721008859, states[0] = -95.204490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1730736302, states[0] = 14.162989, states[40]= 0.006494
Saving checkpoint... 
Iteration: 1740788384, states[0] = -95.167040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1750697896, states[0] = -95.185483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1760535986, states[0] = -93.098489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1770086327, states[0] = -26.282858, states[40]= 0.000640
Saving checkpoint... 
Iteration: 1779905989, states[0] = 28.487092, states[40]= 0.115387
Saving checkpoint... 
Iteration: 1789556445, states[0] = 2.875998, states[40]= 0.005289
Saving checkpoint... 
Iteration: 1799161174, states[0] = -0.396464, states[40]= 0.004836
Saving checkpoint... 
Iteration: 1808904176, states[0] = -95.065858, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1818760588, states[0] = -94.971945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1828572648, states[0] = -0.944015, states[40]= 0.004267
Saving checkpoint... 
Iteration: 1838752199, states[0] = -94.948236, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1848462745, states[0] = -95.049800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1857954710, states[0] = -95.044883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1867933148, states[0] = -95.037941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1877841615, states[0] = -95.005531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1887748193, states[0] = -94.928285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1897328646, states[0] = -94.996004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1907142873, states[0] = -71.380853, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1916854311, states[0] = -95.007202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1926853546, states[0] = -95.006361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1936477354, states[0] = -95.038389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1946294288, states[0] = -94.970464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1956058175, states[0] = 7.381543, states[40]= 0.004980
Saving checkpoint... 
Iteration: 1965862497, states[0] = -95.009125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1975676203, states[0] = -94.792567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1985549115, states[0] = 11.337211, states[40]= 0.005138
Saving checkpoint... 
Iteration: 1995478274, states[0] = -95.037573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2005300880, states[0] = -94.974745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2015206363, states[0] = -94.858683, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2024963772, states[0] = -95.035291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2035039167, states[0] = 15.358257, states[40]= 0.005448
Saving checkpoint... 
Iteration: 2044637249, states[0] = -63.390120, states[40]= 0.000003
Saving checkpoint... 
Iteration: 2054550158, states[0] = 10.902907, states[40]= 0.005118
Saving checkpoint... 
Iteration: 2064268415, states[0] = -94.946393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2073966156, states[0] = -95.035569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2083659933, states[0] = -93.880831, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2093521741, states[0] = 21.150252, states[40]= 0.008546
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.915912
 - CaMKt in component CaMK (millimolar): 0.007007
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.573513
 - nass in component intracellular_ions (millimolar): 6.573573
 - ki in component intracellular_ions (millimolar): 145.401265
 - kss in component intracellular_ions (millimolar): 145.401247
 - cansr in component intracellular_ions (millimolar): 1.323608
 - cajsr in component intracellular_ions (millimolar): 1.286143
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003613
 - hf in component INa (dimensionless): 0.880245
 - hs in component INa (dimensionless): 0.880240
 - j in component INa (dimensionless): 0.880212
 - hsp in component INa (dimensionless): 0.726291
 - jp in component INa (dimensionless): 0.880193
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.711731
 - hLp in component INaL (dimensionless): 0.456873
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.627269
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.703256
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.937627
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999896
 - jca in component ICaL (dimensionless): 0.999980
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001661
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.325409
 - xs1 in component IKs (dimensionless): 0.233371
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997333
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
12:32:26 (212374): called boinc_finish(0)

</stderr_txt>
]]>


CoMBA Research Group Logo
University San Jorge Logo

©2024 Universidad San Jorge