𝕏

Task 55398215

Name HuVeMOp_20240630064831733006_ORdGradInc_k_25-Pueyo_APDR-conf_727_1
Workunit 26306057
Created 30 Jun 2024, 4:49:25 UTC
Sent 30 Jun 2024, 7:04:12 UTC
Report deadline 3 Jul 2024, 16:40:12 UTC
Received 3 Jul 2024, 18:23:16 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 219798
Run time 3 hours 4 min 50 sec
CPU time 2 hours 49 min 5 sec
Validate state Valid
Credit 61.18
Device peak FLOPS 2.33 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.18 MB
Peak swap size 6.38 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064831733006_ORdGradInc_k_25-Pueyo_APDR-conf_727.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064831733006_ORdGradInc_k_25-Pueyo_APDR-conf_727_1_r1294927169_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064831733006_ORdGradInc_k_25-Pueyo_APDR-conf_727_1_r1294927169_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 91.570152
     * GNaL_b in INaL: 0.004737
     * Gto_b in Ito: 0.078209
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.032568
     * GKs_b in IKs: 0.001758
     * GK1_b in IK1: 0.156562
     * Gncx_b in INaCa_i: 0.000957
     * Pnak_b in INaK: 67.581436
     * GKb_b in IKb: 0.003874
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.038617
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12016376, states[0] = 21.163847, states[40]= 0.014691
Saving checkpoint... 
Iteration: 24577007, states[0] = -4.700443, states[40]= 0.003501
Saving checkpoint... 
Iteration: 36961024, states[0] = -94.859998, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48297003, states[0] = -94.787215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 60715921, states[0] = -94.681703, states[40]= 0.000000
Saving checkpoint... 
Iteration: 73049461, states[0] = 10.389737, states[40]= 0.005017
Saving checkpoint... 
Iteration: 85442745, states[0] = -94.834650, states[40]= 0.000000
Saving checkpoint... 
Iteration: 97875360, states[0] = -94.814368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 110183499, states[0] = -94.604215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 122483069, states[0] = -94.836652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 135383321, states[0] = -94.814042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 148252666, states[0] = -94.723492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 161054321, states[0] = 8.470837, states[40]= 0.004930
Saving checkpoint... 
Iteration: 173836058, states[0] = -94.792667, states[40]= 0.000000
Saving checkpoint... 
Iteration: 186234830, states[0] = -94.698452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 198983567, states[0] = -94.834640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 211620946, states[0] = -44.631316, states[40]= 0.000061
Saving checkpoint... 
Iteration: 222970012, states[0] = -94.832608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 235431161, states[0] = -94.825554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 247980319, states[0] = -94.833990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 260521206, states[0] = 20.566595, states[40]= 0.008742
Saving checkpoint... 
Iteration: 273077843, states[0] = -3.958355, states[40]= 0.003636
Saving checkpoint... 
Iteration: 285575893, states[0] = -2.625738, states[40]= 0.003884
Saving checkpoint... 
Iteration: 297941382, states[0] = -94.827544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 310145257, states[0] = -71.953007, states[40]= 0.000001
Saving checkpoint... 
Iteration: 322575391, states[0] = -2.296101, states[40]= 0.003941
Saving checkpoint... 
Iteration: 334943624, states[0] = -94.827946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 347289309, states[0] = -94.760211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 358543383, states[0] = 13.009101, states[40]= 0.005168
Saving checkpoint... 
Iteration: 370151515, states[0] = -81.570089, states[40]= 0.000000
Saving checkpoint... 
Iteration: 381746094, states[0] = -94.713805, states[40]= 0.000000
Saving checkpoint... 
Iteration: 392337995, states[0] = -94.793041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 403601190, states[0] = -25.132758, states[40]= 0.000673
Saving checkpoint... 
Iteration: 416958523, states[0] = -94.830551, states[40]= 0.000000
Saving checkpoint... 
Iteration: 430494603, states[0] = -94.835611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 444157388, states[0] = -89.977372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 457850216, states[0] = -94.799049, states[40]= 0.000000
Saving checkpoint... 
Iteration: 471538411, states[0] = 14.951553, states[40]= 0.005381
Saving checkpoint... 
Iteration: 485233109, states[0] = -94.695312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 498829477, states[0] = -94.788305, states[40]= 0.000000
Saving checkpoint... 
Iteration: 512179114, states[0] = -94.584707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 525131882, states[0] = -56.110447, states[40]= 0.000009
Saving checkpoint... 
Iteration: 537306435, states[0] = -94.773501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 550208611, states[0] = -94.653667, states[40]= 0.000000
Saving checkpoint... 
Iteration: 562240320, states[0] = -94.705788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 573438748, states[0] = -94.826829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 585543421, states[0] = 12.994053, states[40]= 0.005167
Saving checkpoint... 
Iteration: 597976151, states[0] = -94.833130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 610481730, states[0] = -94.833885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 622316616, states[0] = -94.780394, states[40]= 0.000000
Saving checkpoint... 
Iteration: 634686589, states[0] = -94.608404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 646643468, states[0] = -69.535137, states[40]= 0.000001
Saving checkpoint... 
Iteration: 658166771, states[0] = -94.212206, states[40]= 0.000000
Saving checkpoint... 
Iteration: 670446539, states[0] = -94.828274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 682486651, states[0] = -94.834477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 694813536, states[0] = -94.778318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 707231561, states[0] = -94.692808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 718767311, states[0] = -94.738917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 730135796, states[0] = -60.378629, states[40]= 0.000004
Saving checkpoint... 
Iteration: 741260396, states[0] = -94.731243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 753624558, states[0] = -48.359929, states[40]= 0.000034
Saving checkpoint... 
Iteration: 765755726, states[0] = -94.725738, states[40]= 0.000000
Saving checkpoint... 
Iteration: 777857378, states[0] = -94.802067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 789959115, states[0] = -94.830406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 801630136, states[0] = -54.242571, states[40]= 0.000013
Saving checkpoint... 
Iteration: 814163638, states[0] = -93.679332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 826706924, states[0] = -94.650290, states[40]= 0.000000
Saving checkpoint... 
Iteration: 839109863, states[0] = -33.576961, states[40]= 0.000294
Saving checkpoint... 
Iteration: 851442544, states[0] = -94.827396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 863753031, states[0] = -94.722384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 876138380, states[0] = -63.302891, states[40]= 0.000003
Saving checkpoint... 
Iteration: 888340059, states[0] = -94.793790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 899725268, states[0] = -94.682720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 910531100, states[0] = 17.604983, states[40]= 0.005983
Saving checkpoint... 
Iteration: 922880732, states[0] = -94.811077, states[40]= 0.000000
Saving checkpoint... 
Iteration: 935156007, states[0] = -88.369171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 947564542, states[0] = 3.793368, states[40]= 0.004679
Saving checkpoint... 
Iteration: 960398232, states[0] = -94.816661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 973150518, states[0] = -79.941480, states[40]= 0.000000
Saving checkpoint... 
Iteration: 986710711, states[0] = -94.657302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1000247954, states[0] = -94.715846, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1013489127, states[0] = -94.834571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1026969008, states[0] = -94.831813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1040522139, states[0] = 20.327060, states[40]= 0.008218
Saving checkpoint... 
Iteration: 1053999731, states[0] = -94.835791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1065630806, states[0] = -54.957142, states[40]= 0.000011
Saving checkpoint... 
Iteration: 1077477045, states[0] = -94.832943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1088021025, states[0] = 20.612657, states[40]= 0.008857
Saving checkpoint... 
Iteration: 1099815736, states[0] = -94.779509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1111778809, states[0] = -94.750251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1123587319, states[0] = -11.738010, states[40]= 0.002017
Saving checkpoint... 
Iteration: 1135369149, states[0] = -94.806677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1147143742, states[0] = -69.895358, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1159316737, states[0] = -94.780122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1171830206, states[0] = -94.788280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1184348839, states[0] = -94.797929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1196807443, states[0] = -94.773790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1208928077, states[0] = -94.824160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1221324693, states[0] = -94.785036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1233750303, states[0] = -94.718719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1246164780, states[0] = -93.927906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1257792070, states[0] = -94.761936, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1269954165, states[0] = -94.829255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1282465700, states[0] = -94.831141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1294715684, states[0] = -94.666126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1307492344, states[0] = -94.834772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1320171968, states[0] = -94.501829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1332733842, states[0] = -94.695861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1345267034, states[0] = -94.738211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1357902495, states[0] = -94.817633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1370101763, states[0] = -25.689415, states[40]= 0.000646
Saving checkpoint... 
Iteration: 1382829474, states[0] = -94.787726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1395198929, states[0] = -94.634243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1407675844, states[0] = -94.562245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1420198943, states[0] = -94.634255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1432630088, states[0] = -54.190882, states[40]= 0.000013
Saving checkpoint... 
Iteration: 1444347501, states[0] = -94.797123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1457038603, states[0] = 14.878397, states[40]= 0.005370
Saving checkpoint... 
Iteration: 1469729252, states[0] = -94.688722, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1482144787, states[0] = -71.301370, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1494553233, states[0] = 8.951112, states[40]= 0.004949
Saving checkpoint... 
Iteration: 1506874316, states[0] = -95.060184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1519023942, states[0] = -69.186317, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1531086876, states[0] = -94.963228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1543278852, states[0] = -17.598703, states[40]= 0.001291
Saving checkpoint... 
Iteration: 1555305904, states[0] = -48.464579, states[40]= 0.000035
Saving checkpoint... 
Iteration: 1567847993, states[0] = 7.454944, states[40]= 0.005631
Saving checkpoint... 
Iteration: 1580411258, states[0] = 23.356375, states[40]= 0.039115
Saving checkpoint... 
Iteration: 1593118203, states[0] = -64.019414, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1605684213, states[0] = -24.416378, states[40]= 0.000726
Saving checkpoint... 
Iteration: 1616984533, states[0] = -95.118927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1629499704, states[0] = -95.015972, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1642055616, states[0] = -94.902919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1653871939, states[0] = -95.110180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1666362001, states[0] = -94.929744, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1678823573, states[0] = 19.126755, states[40]= 0.008730
Saving checkpoint... 
Iteration: 1691246502, states[0] = -94.713219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1703583232, states[0] = -94.983292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1715826746, states[0] = -76.877164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1727929209, states[0] = -95.064429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1739571505, states[0] = -94.955737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1751160670, states[0] = -0.722095, states[40]= 0.004699
Saving checkpoint... 
Iteration: 1762624664, states[0] = -73.492231, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1775288416, states[0] = -94.994574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1786582886, states[0] = -23.043949, states[40]= 0.000810
Saving checkpoint... 
Iteration: 1798585433, states[0] = -25.912802, states[40]= 0.000643
Saving checkpoint... 
Iteration: 1810841121, states[0] = -94.842073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1823384627, states[0] = -94.847493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1835842882, states[0] = -94.819771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1848309143, states[0] = -94.792132, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1860451168, states[0] = -94.840565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1872512421, states[0] = 22.457364, states[40]= 0.029455
Saving checkpoint... 
Iteration: 1884731737, states[0] = -94.698410, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1896892176, states[0] = -94.818380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1908918878, states[0] = -94.824481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1920950184, states[0] = -94.830159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1933029802, states[0] = 18.025658, states[40]= 0.006150
Saving checkpoint... 
Iteration: 1945118279, states[0] = -41.966412, states[40]= 0.000091
Saving checkpoint... 
Iteration: 1956617122, states[0] = -40.784629, states[40]= 0.000108
Saving checkpoint... 
Iteration: 1969272969, states[0] = -94.744433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1981691200, states[0] = -94.618156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1994253311, states[0] = -94.722183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2006803876, states[0] = -94.770794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2018660096, states[0] = -92.216293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2031139704, states[0] = -64.857255, states[40]= 0.000002
Saving checkpoint... 
Iteration: 2043594301, states[0] = -18.423493, states[40]= 0.001086
Saving checkpoint... 
Iteration: 2056097275, states[0] = -21.322508, states[40]= 0.000871
Saving checkpoint... 
Iteration: 2068484391, states[0] = -94.833254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2080789053, states[0] = -94.758817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2093163445, states[0] = -93.627892, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.710968
 - CaMKt in component CaMK (millimolar): 0.006844
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.693489
 - nass in component intracellular_ions (millimolar): 6.693546
 - ki in component intracellular_ions (millimolar): 145.284578
 - kss in component intracellular_ions (millimolar): 145.284560
 - cansr in component intracellular_ions (millimolar): 1.309025
 - cajsr in component intracellular_ions (millimolar): 1.271802
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003689
 - hf in component INa (dimensionless): 0.876649
 - hs in component INa (dimensionless): 0.876644
 - j in component INa (dimensionless): 0.876616
 - hsp in component INa (dimensionless): 0.719546
 - jp in component INa (dimensionless): 0.876597
 - mL in component INaL (dimensionless): 0.000051
 - hL in component INaL (dimensionless): 0.705847
 - hLp in component INaL (dimensionless): 0.449248
 - a in component Ito (dimensionless): 0.000632
 - iF in component Ito (dimensionless): 0.999865
 - iS in component Ito (dimensionless): 0.625071
 - ap in component Ito (dimensionless): 0.000322
 - iFp in component Ito (dimensionless): 0.999865
 - iSp in component Ito (dimensionless): 0.700702
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.939596
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999900
 - jca in component ICaL (dimensionless): 0.999981
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001592
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.320584
 - xs1 in component IKs (dimensionless): 0.231119
 - xs2 in component IKs (dimensionless): 0.000090
 - xk1 in component IK1 (dimensionless): 0.997387
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
20:22:42 (8224): called boinc_finish(0)

</stderr_txt>
]]>


CoMBA Research Group Logo
University San Jorge Logo

©2024 Universidad San Jorge