𝕏

Task 55397252

Name HuVeMOp_20240630064831733006_ORdGradInc_k_25-Pueyo_APDR-conf_308_1
Workunit 26305576
Created 30 Jun 2024, 4:48:51 UTC
Sent 30 Jun 2024, 6:59:00 UTC
Report deadline 3 Jul 2024, 16:35:00 UTC
Received 30 Jun 2024, 19:53:28 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 235804
Run time 1 hours 12 min 36 sec
CPU time 1 hours 10 min 41 sec
Validate state Valid
Credit 65.73
Device peak FLOPS 4.93 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.22 MB
Peak swap size 5.29 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064831733006_ORdGradInc_k_25-Pueyo_APDR-conf_308.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064831733006_ORdGradInc_k_25-Pueyo_APDR-conf_308_1_r653364475_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064831733006_ORdGradInc_k_25-Pueyo_APDR-conf_308_1_r653364475_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 112.539910
     * GNaL_b in INaL: 0.006576
     * Gto_b in Ito: 0.077501
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.029736
     * GKs_b in IKs: 0.001986
     * GK1_b in IK1: 0.173369
     * Gncx_b in INaCa_i: 0.000976
     * Pnak_b in INaK: 70.480867
     * GKb_b in IKb: 0.003742
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.022888
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 13299737, states[0] = -95.001805, states[40]= 0.000000
Saving checkpoint... 
Iteration: 32302501, states[0] = -94.966662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 50866125, states[0] = -94.985159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 69665888, states[0] = -90.495089, states[40]= 0.000000
Saving checkpoint... 
Iteration: 88332277, states[0] = -94.955617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 108127250, states[0] = -40.329174, states[40]= 0.000131
Saving checkpoint... 
Iteration: 127264664, states[0] = -94.898009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 146494988, states[0] = -94.996247, states[40]= 0.000000
Saving checkpoint... 
Iteration: 159780124, states[0] = -94.912215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 178135144, states[0] = -47.903493, states[40]= 0.000041
Saving checkpoint... 
Iteration: 191298361, states[0] = -94.927155, states[40]= 0.000000
Saving checkpoint... 
Iteration: 210271067, states[0] = -94.902789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 229175549, states[0] = -94.455577, states[40]= 0.000000
Saving checkpoint... 
Iteration: 247761001, states[0] = -94.891889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 266617795, states[0] = -31.373084, states[40]= 0.000435
Saving checkpoint... 
Iteration: 279546055, states[0] = 14.169562, states[40]= 0.005218
Saving checkpoint... 
Iteration: 298270298, states[0] = -94.901789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 317443654, states[0] = -94.987059, states[40]= 0.000000
Saving checkpoint... 
Iteration: 336121032, states[0] = -34.296431, states[40]= 0.000305
Saving checkpoint... 
Iteration: 355277340, states[0] = -94.908701, states[40]= 0.000000
Saving checkpoint... 
Iteration: 374922917, states[0] = -94.982571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 394117956, states[0] = -31.515567, states[40]= 0.000428
Saving checkpoint... 
Iteration: 413366417, states[0] = -94.965039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 432377074, states[0] = -94.969072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 451732812, states[0] = -94.855123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 470863026, states[0] = -94.963631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 489650591, states[0] = -65.047604, states[40]= 0.000002
Saving checkpoint... 
Iteration: 508617451, states[0] = -31.061566, states[40]= 0.000450
Saving checkpoint... 
Iteration: 527292648, states[0] = -94.922117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 540712190, states[0] = -94.821522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 558543341, states[0] = 15.169107, states[40]= 0.005307
Saving checkpoint... 
Iteration: 577660141, states[0] = -79.505268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 596577237, states[0] = 0.893978, states[40]= 0.004386
Saving checkpoint... 
Iteration: 615320580, states[0] = -94.941986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 633703012, states[0] = -94.804750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 652354899, states[0] = -94.960047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 671121069, states[0] = -34.329604, states[40]= 0.000303
Saving checkpoint... 
Iteration: 690235619, states[0] = -94.859097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 709396664, states[0] = -94.975373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 728367004, states[0] = -94.965091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 748497300, states[0] = -94.995030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 767547879, states[0] = 13.489158, states[40]= 0.005171
Saving checkpoint... 
Iteration: 781127341, states[0] = -40.146628, states[40]= 0.000135
Saving checkpoint... 
Iteration: 800420263, states[0] = -94.981693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 813815232, states[0] = -94.938472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 832669430, states[0] = -92.651687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 852291162, states[0] = -94.920708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 865398690, states[0] = -94.975887, states[40]= 0.000000
Saving checkpoint... 
Iteration: 884353665, states[0] = -94.959363, states[40]= 0.000000
Saving checkpoint... 
Iteration: 903315361, states[0] = -94.938505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 922213871, states[0] = -94.824252, states[40]= 0.000000
Saving checkpoint... 
Iteration: 940957351, states[0] = -94.989200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 953972086, states[0] = -94.991555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 972313502, states[0] = -94.937242, states[40]= 0.000000
Saving checkpoint... 
Iteration: 990753540, states[0] = -94.882691, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1009550706, states[0] = 12.420996, states[40]= 0.005112
Saving checkpoint... 
Iteration: 1028604868, states[0] = -19.854716, states[40]= 0.001007
Saving checkpoint... 
Iteration: 1042449753, states[0] = -94.987792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1061254805, states[0] = -94.884174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1080225066, states[0] = -94.842848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1098867185, states[0] = -94.964951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1117616652, states[0] = -30.344307, states[40]= 0.000486
Saving checkpoint... 
Iteration: 1136364329, states[0] = -94.963784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1155651485, states[0] = -66.190879, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1174333390, states[0] = -94.949125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1193551496, states[0] = 12.119569, states[40]= 0.005098
Saving checkpoint... 
Iteration: 1211964137, states[0] = -94.990173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1225291218, states[0] = -94.920541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1243792702, states[0] = -94.921751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1257706121, states[0] = -94.810167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1277320815, states[0] = -94.941753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1290504970, states[0] = 30.440723, states[40]= 0.140197
Saving checkpoint... 
Iteration: 1304017753, states[0] = 22.764167, states[40]= 0.013133
Saving checkpoint... 
Iteration: 1323075739, states[0] = 1.674531, states[40]= 0.004477
Saving checkpoint... 
Iteration: 1342249106, states[0] = -94.876994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1355567000, states[0] = 5.810089, states[40]= 0.004822
Saving checkpoint... 
Iteration: 1369716562, states[0] = -94.828641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1390062157, states[0] = 7.882951, states[40]= 0.004929
Saving checkpoint... 
Iteration: 1410172587, states[0] = -93.964413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1423836763, states[0] = -94.950797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1437434034, states[0] = -94.984453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1456798137, states[0] = -94.925947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1476034692, states[0] = 18.191999, states[40]= 0.005843
Saving checkpoint... 
Iteration: 1490702305, states[0] = -94.802926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1510943100, states[0] = -86.214097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1530794833, states[0] = -95.107175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1550140276, states[0] = 13.709853, states[40]= 0.006272
Saving checkpoint... 
Iteration: 1570129696, states[0] = -95.179813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1590198223, states[0] = -95.133579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1610032229, states[0] = -95.188009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1629840487, states[0] = -95.198988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1649745598, states[0] = 10.921134, states[40]= 0.005955
Saving checkpoint... 
Iteration: 1669258409, states[0] = 4.104517, states[40]= 0.005347
Saving checkpoint... 
Iteration: 1688921339, states[0] = -95.174855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1708558039, states[0] = 4.312514, states[40]= 0.005368
Saving checkpoint... 
Iteration: 1728273576, states[0] = -95.232331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1747690759, states[0] = -95.122651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1767412781, states[0] = -46.717733, states[40]= 0.000052
Saving checkpoint... 
Iteration: 1787081463, states[0] = -95.238500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1806668670, states[0] = -94.072453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1826689456, states[0] = -94.802647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1846443923, states[0] = -95.001263, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1866084259, states[0] = -3.524616, states[40]= 0.003700
Saving checkpoint... 
Iteration: 1885227455, states[0] = -94.850986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1904902641, states[0] = -94.979050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1924377755, states[0] = -94.969913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1943772404, states[0] = -94.903774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1963582717, states[0] = -2.234916, states[40]= 0.003925
Saving checkpoint... 
Iteration: 1983135455, states[0] = -48.206491, states[40]= 0.000039
Saving checkpoint... 
Iteration: 2002214272, states[0] = -94.824436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2021633654, states[0] = -46.350382, states[40]= 0.000053
Saving checkpoint... 
Iteration: 2045203976, states[0] = -94.805736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2064473284, states[0] = -94.991076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2083700948, states[0] = -94.799979, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.870411
 - CaMKt in component CaMK (millimolar): 0.006947
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.610223
 - nass in component intracellular_ions (millimolar): 6.610282
 - ki in component intracellular_ions (millimolar): 145.368785
 - kss in component intracellular_ions (millimolar): 145.368767
 - cansr in component intracellular_ions (millimolar): 1.308978
 - cajsr in component intracellular_ions (millimolar): 1.270586
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003630
 - hf in component INa (dimensionless): 0.879454
 - hs in component INa (dimensionless): 0.879450
 - j in component INa (dimensionless): 0.879421
 - hsp in component INa (dimensionless): 0.724801
 - jp in component INa (dimensionless): 0.879402
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.707716
 - hLp in component INaL (dimensionless): 0.447079
 - a in component Ito (dimensionless): 0.000625
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.614804
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.688197
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.930057
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999865
 - jca in component ICaL (dimensionless): 0.999975
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001599
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.348526
 - xs1 in component IKs (dimensionless): 0.251176
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997345
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
03:56:35 (40756): called boinc_finish(0)

</stderr_txt>
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