𝕏

Task 55396580

Name HuVeMOp_20240630064555304022_ORdGradInc_k_25-Pieske_333-conf_492_1
Workunit 26305242
Created 30 Jun 2024, 4:48:24 UTC
Sent 30 Jun 2024, 6:55:56 UTC
Report deadline 3 Jul 2024, 6:55:56 UTC
Received 30 Jun 2024, 10:32:56 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 239941
Run time 2 hours 49 min 11 sec
CPU time 1 hours 37 min 28 sec
Validate state Valid
Credit 44.25
Device peak FLOPS 5.16 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 10.13 MB
Peak swap size 32.86 GB
Peak disk usage 0.13 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064555304022_ORdGradInc_k_25-Pieske_333-conf_492.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064555304022_ORdGradInc_k_25-Pieske_333-conf_492_1_r1179508637_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064555304022_ORdGradInc_k_25-Pieske_333-conf_492_1_r1179508637_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 119.336456
     * GNaL_b in INaL: 0.006205
     * Gto_b in Ito: 0.096269
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032414
     * GKs_b in IKs: 0.001962
     * GK1_b in IK1: 0.160916
     * Gncx_b in INaCa_i: 0.000973
     * Pnak_b in INaK: 67.439873
     * GKb_b in IKb: 0.003736
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032139
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 15136247, states[0] = -87.556443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 33755592, states[0] = -60.191239, states[40]= 0.000008
Saving checkpoint... 
Iteration: 50421584, states[0] = -62.294128, states[40]= 0.000006
Saving checkpoint... 
Iteration: 66721987, states[0] = -18.697987, states[40]= 0.001443
Saving checkpoint... 
Iteration: 83483453, states[0] = -87.668313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 98458406, states[0] = -87.585385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 116682309, states[0] = 14.243721, states[40]= 0.008335
Saving checkpoint... 
Iteration: 133052359, states[0] = -24.226927, states[40]= 0.000886
Saving checkpoint... 
Iteration: 149483603, states[0] = -87.693759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 166123549, states[0] = -87.610622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 182655471, states[0] = 23.640509, states[40]= 0.091450
Saving checkpoint... 
Iteration: 199022208, states[0] = 4.230781, states[40]= 0.006799
Saving checkpoint... 
Iteration: 215173464, states[0] = 13.657514, states[40]= 0.008176
Saving checkpoint... 
Iteration: 230316858, states[0] = 24.202914, states[40]= 0.101051
Saving checkpoint... 
Iteration: 248044407, states[0] = -29.222583, states[40]= 0.000571
Saving checkpoint... 
Iteration: 264410900, states[0] = -80.586385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 280637479, states[0] = -87.695083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 296939571, states[0] = -87.593316, states[40]= 0.000000
Saving checkpoint... 
Iteration: 313853633, states[0] = -5.093800, states[40]= 0.004781
Saving checkpoint... 
Iteration: 330695060, states[0] = -18.302144, states[40]= 0.001502
Saving checkpoint... 
Iteration: 346275093, states[0] = -87.621896, states[40]= 0.000000
Saving checkpoint... 
Iteration: 361494950, states[0] = 11.999508, states[40]= 0.007832
Saving checkpoint... 
Iteration: 377812153, states[0] = 19.281548, states[40]= 0.015214
Saving checkpoint... 
Iteration: 393386829, states[0] = -62.483131, states[40]= 0.000006
Saving checkpoint... 
Iteration: 408803123, states[0] = 21.432444, states[40]= 0.042178
Saving checkpoint... 
Iteration: 424460609, states[0] = 33.765900, states[40]= 0.124758
Saving checkpoint... 
Iteration: 440117168, states[0] = -87.682306, states[40]= 0.000000
Saving checkpoint... 
Iteration: 455424378, states[0] = -87.595808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 471033676, states[0] = -45.136807, states[40]= 0.000081
Saving checkpoint... 
Iteration: 485877973, states[0] = -63.090343, states[40]= 0.000005
Saving checkpoint... 
Iteration: 502039817, states[0] = -58.255867, states[40]= 0.000011
Saving checkpoint... 
Iteration: 517408892, states[0] = -87.547675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 531515188, states[0] = -28.009086, states[40]= 0.000639
Saving checkpoint... 
Iteration: 545400468, states[0] = -87.483728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 563780543, states[0] = 31.264557, states[40]= 0.133568
Saving checkpoint... 
Iteration: 578292078, states[0] = 19.290647, states[40]= 0.015260
Saving checkpoint... 
Iteration: 595454135, states[0] = 20.335470, states[40]= 0.023420
Saving checkpoint... 
Iteration: 611476624, states[0] = 7.549664, states[40]= 0.007227
Saving checkpoint... 
Iteration: 625948961, states[0] = 21.088989, states[40]= 0.035046
Saving checkpoint... 
Iteration: 642254915, states[0] = -87.654870, states[40]= 0.000000
Saving checkpoint... 
Iteration: 658199351, states[0] = -71.688403, states[40]= 0.000001
Saving checkpoint... 
Iteration: 674541171, states[0] = -85.200209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 690522821, states[0] = -61.023432, states[40]= 0.000007
Saving checkpoint... 
Iteration: 706525610, states[0] = -67.939146, states[40]= 0.000002
Saving checkpoint... 
Iteration: 722884699, states[0] = -87.513640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 738786391, states[0] = 14.434134, states[40]= 0.008396
Saving checkpoint... 
Iteration: 752914053, states[0] = -87.666079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 769156527, states[0] = -25.830150, states[40]= 0.000773
Saving checkpoint... 
Iteration: 785389661, states[0] = -87.587854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 801671226, states[0] = -50.655652, states[40]= 0.000036
Saving checkpoint... 
Iteration: 817832722, states[0] = -45.685194, states[40]= 0.000075
Saving checkpoint... 
Iteration: 833847542, states[0] = -70.153645, states[40]= 0.000002
Saving checkpoint... 
Iteration: 850107640, states[0] = 14.955738, states[40]= 0.008580


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064555304022_ORdGradInc_k_25-Pieske_333-conf_492.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064555304022_ORdGradInc_k_25-Pieske_333-conf_492_1_r1179508637_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064555304022_ORdGradInc_k_25-Pieske_333-conf_492_1_r1179508637_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 119.336456
     * GNaL_b in INaL: 0.006205
     * Gto_b in Ito: 0.096269
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032414
     * GKs_b in IKs: 0.001962
     * GK1_b in IK1: 0.160916
     * Gncx_b in INaCa_i: 0.000973
     * Pnak_b in INaK: 67.439873
     * GKb_b in IKb: 0.003736
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032139
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 850107640
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: 14.955738 (After loading)
 - states[40]: 0.008580 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 881172047, states[0] = -63.514418, states[40]= 0.000005
Saving checkpoint... 
Iteration: 902870148, states[0] = -87.545693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 919978953, states[0] = -31.638969, states[40]= 0.000450
Saving checkpoint... 
Iteration: 936980929, states[0] = -36.688173, states[40]= 0.000253


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064555304022_ORdGradInc_k_25-Pieske_333-conf_492.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064555304022_ORdGradInc_k_25-Pieske_333-conf_492_1_r1179508637_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064555304022_ORdGradInc_k_25-Pieske_333-conf_492_1_r1179508637_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 119.336456
     * GNaL_b in INaL: 0.006205
     * Gto_b in Ito: 0.096269
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032414
     * GKs_b in IKs: 0.001962
     * GK1_b in IK1: 0.160916
     * Gncx_b in INaCa_i: 0.000973
     * Pnak_b in INaK: 67.439873
     * GKb_b in IKb: 0.003736
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032139
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 936980929
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -36.688173 (After loading)
 - states[40]: 0.000253 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 957790035, states[0] = -6.052853, states[40]= 0.004498
Saving checkpoint... 
Iteration: 973440502, states[0] = 7.492590, states[40]= 0.007220
Saving checkpoint... 
Iteration: 990416279, states[0] = 19.753828, states[40]= 0.018024
Saving checkpoint... 
Iteration: 1007273025, states[0] = 5.566210, states[40]= 0.006980
Saving checkpoint... 
Iteration: 1022313016, states[0] = -46.718897, states[40]= 0.000064
Saving checkpoint... 
Iteration: 1039286770, states[0] = -12.498536, states[40]= 0.002646
Saving checkpoint... 
Iteration: 1054488682, states[0] = -64.510133, states[40]= 0.000004


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064555304022_ORdGradInc_k_25-Pieske_333-conf_492.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064555304022_ORdGradInc_k_25-Pieske_333-conf_492_1_r1179508637_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064555304022_ORdGradInc_k_25-Pieske_333-conf_492_1_r1179508637_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 119.336456
     * GNaL_b in INaL: 0.006205
     * Gto_b in Ito: 0.096269
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032414
     * GKs_b in IKs: 0.001962
     * GK1_b in IK1: 0.160916
     * Gncx_b in INaCa_i: 0.000973
     * Pnak_b in INaK: 67.439873
     * GKb_b in IKb: 0.003736
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032139
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1054488682
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -64.510133 (After loading)
 - states[40]: 0.000004 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1080912146, states[0] = 17.786221, states[40]= 0.010877
Saving checkpoint... 
Iteration: 1099068362, states[0] = 21.069958, states[40]= 0.034683
Saving checkpoint... 
Iteration: 1115501084, states[0] = -86.767085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1131697445, states[0] = -87.624158, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1146645372, states[0] = -63.324053, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1163170024, states[0] = -87.434536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1179630108, states[0] = -46.009337, states[40]= 0.000071
Saving checkpoint... 
Iteration: 1193539815, states[0] = -87.675276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1209943964, states[0] = -23.279594, states[40]= 0.000960
Saving checkpoint... 
Iteration: 1226069634, states[0] = 15.173532, states[40]= 0.008668
Saving checkpoint... 
Iteration: 1241844079, states[0] = -87.587545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1257777432, states[0] = -30.160064, states[40]= 0.000522
Saving checkpoint... 
Iteration: 1272614422, states[0] = -37.228385, states[40]= 0.000236
Saving checkpoint... 
Iteration: 1289247649, states[0] = 3.285260, states[40]= 0.006660
Saving checkpoint... 
Iteration: 1305516105, states[0] = -87.633773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1321625357, states[0] = -59.500532, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1337635572, states[0] = -78.634608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1353716821, states[0] = 18.378363, states[40]= 0.012059
Saving checkpoint... 
Iteration: 1369435982, states[0] = -34.363792, states[40]= 0.000334
Saving checkpoint... 
Iteration: 1385238101, states[0] = 3.242116, states[40]= 0.006653
Saving checkpoint... 
Iteration: 1401172059, states[0] = -87.629420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1415305930, states[0] = -87.033032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1431249357, states[0] = -15.016159, states[40]= 0.002071
Saving checkpoint... 
Iteration: 1447113128, states[0] = -59.975848, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1462986859, states[0] = -87.579055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1478661512, states[0] = -87.618844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1494646861, states[0] = -87.561102, states[40]= 0.000000
Total time: 3000033.300000
State Variables:
 - v in component membrane (millivolt): -87.571870
 - CaMKt in component CaMK (millimolar): 0.045101
 - cass in component intracellular_ions (millimolar): 0.000117
 - nai in component intracellular_ions (millimolar): 7.187234
 - nass in component intracellular_ions (millimolar): 7.187384
 - ki in component intracellular_ions (millimolar): 144.725409
 - kss in component intracellular_ions (millimolar): 144.725376
 - cansr in component intracellular_ions (millimolar): 1.653148
 - cajsr in component intracellular_ions (millimolar): 1.207392
 - cai in component intracellular_ions (millimolar): 0.000113
 - m in component INa (dimensionless): 0.007573
 - hf in component INa (dimensionless): 0.687415
 - hs in component INa (dimensionless): 0.687164
 - j in component INa (dimensionless): 0.676645
 - hsp in component INa (dimensionless): 0.441473
 - jp in component INa (dimensionless): 0.650360
 - mL in component INaL (dimensionless): 0.000200
 - hL in component INaL (dimensionless): 0.290439
 - hLp in component INaL (dimensionless): 0.134482
 - a in component Ito (dimensionless): 0.001022
 - iF in component Ito (dimensionless): 0.999529
 - iS in component Ito (dimensionless): 0.176307
 - ap in component Ito (dimensionless): 0.000521
 - iFp in component Ito (dimensionless): 0.999529
 - iSp in component Ito (dimensionless): 0.213453
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.809136
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.967894
 - jca in component ICaL (dimensionless): 0.948841
 - ffp in component ICaL (dimensionless): 0.999868
 - fcafp in component ICaL (dimensionless): 0.999992
 - nca in component ICaL (dimensionless): 0.009782
 - xrf in component IKr (dimensionless): 0.027881
 - xrs in component IKr (dimensionless): 0.789403
 - xs1 in component IKs (dimensionless): 0.455067
 - xs2 in component IKs (dimensionless): 0.001186
 - xk1 in component IK1 (dimensionless): 0.996845
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
11:26:03 (4115): called boinc_finish(0)

</stderr_txt>
]]>