𝕏

Task 55396313

Name HuVeMOp_20240630064555304022_ORdGradInc_k_25-Pueyo_APDR-conf_882_0
Workunit 26305109
Created 30 Jun 2024, 4:48:04 UTC
Sent 30 Jun 2024, 6:59:00 UTC
Report deadline 3 Jul 2024, 16:35:00 UTC
Received 30 Jun 2024, 19:53:28 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 235804
Run time 1 hours 12 min 43 sec
CPU time 1 hours 10 min 46 sec
Validate state Valid
Credit 62.63
Device peak FLOPS 4.93 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.25 MB
Peak swap size 5.32 MB
Peak disk usage 0.27 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064555304022_ORdGradInc_k_25-Pueyo_APDR-conf_882.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064555304022_ORdGradInc_k_25-Pueyo_APDR-conf_882_0_r907573986_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064555304022_ORdGradInc_k_25-Pueyo_APDR-conf_882_0_r907573986_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 100.635224
     * GNaL_b in INaL: 0.005708
     * Gto_b in Ito: 0.099352
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.030086
     * GKs_b in IKs: 0.001900
     * GK1_b in IK1: 0.165160
     * Gncx_b in INaCa_i: 0.000975
     * Pnak_b in INaK: 74.650724
     * GKb_b in IKb: 0.003669
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.026524
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 13527104, states[0] = 18.263711, states[40]= 0.005953
Saving checkpoint... 
Iteration: 32760947, states[0] = -94.922247, states[40]= 0.000000
Saving checkpoint... 
Iteration: 45540296, states[0] = 15.233121, states[40]= 0.004832
Saving checkpoint... 
Iteration: 64476576, states[0] = -95.000056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 82461040, states[0] = -94.989653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 101145944, states[0] = -57.471032, states[40]= 0.000008
Saving checkpoint... 
Iteration: 119695410, states[0] = -94.758849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 138995982, states[0] = -94.986416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 157644721, states[0] = -55.816670, states[40]= 0.000011
Saving checkpoint... 
Iteration: 175959692, states[0] = -94.979478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 194704939, states[0] = -94.777477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 212833225, states[0] = -94.934514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 231496277, states[0] = -94.984626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 250382846, states[0] = -94.958240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 269533210, states[0] = 17.799047, states[40]= 0.005192
Saving checkpoint... 
Iteration: 282327759, states[0] = -94.930882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 301228738, states[0] = -94.822349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 319751300, states[0] = -94.857286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 338591872, states[0] = -7.671244, states[40]= 0.002738
Saving checkpoint... 
Iteration: 357108632, states[0] = -21.962405, states[40]= 0.000878
Saving checkpoint... 
Iteration: 376017448, states[0] = 20.876027, states[40]= 0.011672
Saving checkpoint... 
Iteration: 395057206, states[0] = 9.899952, states[40]= 0.004667
Saving checkpoint... 
Iteration: 413600509, states[0] = -14.816562, states[40]= 0.001453
Saving checkpoint... 
Iteration: 432521613, states[0] = 20.358871, states[40]= 0.007658
Saving checkpoint... 
Iteration: 451186288, states[0] = -94.702120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 464498209, states[0] = -94.984586, states[40]= 0.000000
Saving checkpoint... 
Iteration: 477728887, states[0] = -94.822458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 496970463, states[0] = -94.980508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 510442557, states[0] = -94.975202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 523866544, states[0] = -94.951334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 537447526, states[0] = -94.976228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 556386467, states[0] = -94.959287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 572296128, states[0] = -94.906882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 586924817, states[0] = -94.970987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 606704678, states[0] = -94.776265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 626939957, states[0] = -94.974547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 641810477, states[0] = -94.918539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 655128678, states[0] = -39.853516, states[40]= 0.000141
Saving checkpoint... 
Iteration: 674212884, states[0] = -94.792824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 693511718, states[0] = 21.287665, states[40]= 0.034569
Saving checkpoint... 
Iteration: 712432270, states[0] = -94.972724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 725935375, states[0] = -94.973440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 745298298, states[0] = -94.908633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 764908970, states[0] = -94.966512, states[40]= 0.000000
Saving checkpoint... 
Iteration: 784829400, states[0] = -94.931521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 804883862, states[0] = -94.958141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 824449429, states[0] = -94.976402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 844035302, states[0] = 17.208369, states[40]= 0.005051
Saving checkpoint... 
Iteration: 863869438, states[0] = -94.952334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 883688203, states[0] = -94.721956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 902892738, states[0] = -94.961243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 922369349, states[0] = -94.952252, states[40]= 0.000000
Saving checkpoint... 
Iteration: 942076141, states[0] = 1.953891, states[40]= 0.004320
Saving checkpoint... 
Iteration: 961890110, states[0] = -94.960286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 981843443, states[0] = -94.939629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1001368861, states[0] = -94.951984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1021160312, states[0] = -74.698636, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1040531477, states[0] = 18.265401, states[40]= 0.005339
Saving checkpoint... 
Iteration: 1060467866, states[0] = -94.979650, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1079915085, states[0] = -94.968028, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1099523632, states[0] = 20.021979, states[40]= 0.006780
Saving checkpoint... 
Iteration: 1119181092, states[0] = -94.543924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1138743550, states[0] = -94.845511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1158143472, states[0] = -54.437507, states[40]= 0.000014
Saving checkpoint... 
Iteration: 1177469581, states[0] = -94.979852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1197034977, states[0] = 17.302222, states[40]= 0.005071
Saving checkpoint... 
Iteration: 1216481614, states[0] = -94.981729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1235801278, states[0] = -94.910782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1255429081, states[0] = -94.971550, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1278491502, states[0] = -94.983094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1297677387, states[0] = -94.141287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1316673994, states[0] = -93.111810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1330153705, states[0] = -65.704181, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1348844806, states[0] = -94.940098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1368015988, states[0] = 21.000821, states[40]= 0.014545
Saving checkpoint... 
Iteration: 1387126242, states[0] = -37.606229, states[40]= 0.000195
Saving checkpoint... 
Iteration: 1406160085, states[0] = -74.349348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1424919783, states[0] = -94.969050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1443945031, states[0] = -94.975031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1462583109, states[0] = -1.784698, states[40]= 0.003859
Saving checkpoint... 
Iteration: 1481413895, states[0] = -94.967395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1500510322, states[0] = -95.077078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1519314730, states[0] = -46.089788, states[40]= 0.000056
Saving checkpoint... 
Iteration: 1537976590, states[0] = -95.061029, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1556983716, states[0] = -95.235475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1575693454, states[0] = -25.706289, states[40]= 0.000695
Saving checkpoint... 
Iteration: 1588955287, states[0] = -94.844155, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1608012538, states[0] = 21.805058, states[40]= 0.030194
Saving checkpoint... 
Iteration: 1626633028, states[0] = 16.083562, states[40]= 0.006183
Saving checkpoint... 
Iteration: 1646204028, states[0] = -36.878317, states[40]= 0.000213
Saving checkpoint... 
Iteration: 1665333870, states[0] = 15.736887, states[40]= 0.006109
Saving checkpoint... 
Iteration: 1684499154, states[0] = -95.258205, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1703887820, states[0] = -95.110017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1723101922, states[0] = -95.140193, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1742510852, states[0] = -44.207633, states[40]= 0.000075
Saving checkpoint... 
Iteration: 1761596431, states[0] = -95.256397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1775262181, states[0] = -95.026714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1794735773, states[0] = -76.027640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1813842764, states[0] = -94.982365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1832774874, states[0] = -94.911303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1851521867, states[0] = 20.182275, states[40]= 0.007476
Saving checkpoint... 
Iteration: 1870595022, states[0] = -10.552556, states[40]= 0.002158
Saving checkpoint... 
Iteration: 1889394757, states[0] = -94.965779, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1908174188, states[0] = -93.289911, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1926935329, states[0] = -94.973953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1945942513, states[0] = -94.974890, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1965567025, states[0] = 6.057038, states[40]= 0.004584
Saving checkpoint... 
Iteration: 1984300079, states[0] = -94.909415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1997646970, states[0] = -58.121680, states[40]= 0.000007
Saving checkpoint... 
Iteration: 2016624970, states[0] = -36.452795, states[40]= 0.000229
Saving checkpoint... 
Iteration: 2035619008, states[0] = -31.105738, states[40]= 0.000448
Saving checkpoint... 
Iteration: 2054567395, states[0] = 5.911732, states[40]= 0.004578
Saving checkpoint... 
Iteration: 2073430856, states[0] = -94.971319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2086428542, states[0] = -94.970741, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.859408
 - CaMKt in component CaMK (millimolar): 0.007335
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.491584
 - nass in component intracellular_ions (millimolar): 6.491644
 - ki in component intracellular_ions (millimolar): 145.482048
 - kss in component intracellular_ions (millimolar): 145.482030
 - cansr in component intracellular_ions (millimolar): 1.325041
 - cajsr in component intracellular_ions (millimolar): 1.285864
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003634
 - hf in component INa (dimensionless): 0.879262
 - hs in component INa (dimensionless): 0.879257
 - j in component INa (dimensionless): 0.879226
 - hsp in component INa (dimensionless): 0.724438
 - jp in component INa (dimensionless): 0.879205
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.706557
 - hLp in component INaL (dimensionless): 0.444263
 - a in component Ito (dimensionless): 0.000625
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.612265
 - ap in component Ito (dimensionless): 0.000319
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.685731
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.932289
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999871
 - jca in component ICaL (dimensionless): 0.999974
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001642
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.330566
 - xs1 in component IKs (dimensionless): 0.252411
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997348
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
04:43:35 (16456): called boinc_finish(0)

</stderr_txt>
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