𝕏

Task 55395812

Name HuVeMOp_20240630064555304022_ORdGradInc_k_25-CLVPET_Block_Kr_70-conf_245_1
Workunit 26304858
Created 30 Jun 2024, 4:47:43 UTC
Sent 30 Jun 2024, 6:47:48 UTC
Report deadline 3 Jul 2024, 9:40:36 UTC
Received 30 Jun 2024, 11:26:27 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 163832
Run time 2 hours 20 min 23 sec
CPU time 2 hours 13 min 42 sec
Validate state Valid
Credit 48.27
Device peak FLOPS 2.63 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.20 MB
Peak swap size 6.23 MB
Peak disk usage 0.05 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064555304022_ORdGradInc_k_25-CLVPET_Block_Kr_70-conf_245.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064555304022_ORdGradInc_k_25-CLVPET_Block_Kr_70-conf_245_1_r298570588_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064555304022_ORdGradInc_k_25-CLVPET_Block_Kr_70-conf_245_1_r298570588_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 93.356077
     * GNaL_b in INaL: 0.004796
     * Gto_b in Ito: 0.084094
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.009712
     * GKs_b in IKs: 0.002044
     * GK1_b in IK1: 0.162777
     * Gncx_b in INaCa_i: 0.000979
     * Pnak_b in INaK: 74.361557
     * GKb_b in IKb: 0.003854
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.020044
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 13073209, states[0] = 13.946541, states[40]= 0.004464
Saving checkpoint... 
Iteration: 26189214, states[0] = -31.939715, states[40]= 0.002775
Saving checkpoint... 
Iteration: 39213783, states[0] = -39.450637, states[40]= 0.001177
Saving checkpoint... 
Iteration: 52123069, states[0] = -3.462070, states[40]= 0.004232
Saving checkpoint... 
Iteration: 64987719, states[0] = -94.732936, states[40]= 0.000000
Saving checkpoint... 
Iteration: 78095442, states[0] = 8.038624, states[40]= 0.005111
Saving checkpoint... 
Iteration: 91150050, states[0] = -14.736504, states[40]= 0.002666
Saving checkpoint... 
Iteration: 102755084, states[0] = -52.857493, states[40]= 0.000149
Saving checkpoint... 
Iteration: 115772744, states[0] = -61.938819, states[40]= 0.000031
Saving checkpoint... 
Iteration: 128741230, states[0] = -46.154827, states[40]= 0.000433
Saving checkpoint... 
Iteration: 141768056, states[0] = -58.537781, states[40]= 0.000056
Saving checkpoint... 
Iteration: 154792141, states[0] = -79.069466, states[40]= 0.000002
Saving checkpoint... 
Iteration: 167842439, states[0] = -94.581781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 180997422, states[0] = -94.707691, states[40]= 0.000000
Saving checkpoint... 
Iteration: 194190699, states[0] = -27.752128, states[40]= 0.004088
Saving checkpoint... 
Iteration: 207281950, states[0] = -67.182270, states[40]= 0.000012
Saving checkpoint... 
Iteration: 220309879, states[0] = -94.117412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 233314303, states[0] = -94.416674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 246326335, states[0] = -94.548246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 259352391, states[0] = -94.594686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 272351733, states[0] = -94.593606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 285377282, states[0] = -94.626868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 298481321, states[0] = -94.699897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 311586215, states[0] = 11.732849, states[40]= 0.004973
Saving checkpoint... 
Iteration: 324589748, states[0] = 10.506255, states[40]= 0.005034
Saving checkpoint... 
Iteration: 337213266, states[0] = -35.019119, states[40]= 0.001968
Saving checkpoint... 
Iteration: 350198332, states[0] = -30.068675, states[40]= 0.003371
Saving checkpoint... 
Iteration: 363222860, states[0] = -38.436233, states[40]= 0.001280
Saving checkpoint... 
Iteration: 376235435, states[0] = -43.235104, states[40]= 0.000662
Saving checkpoint... 
Iteration: 389212420, states[0] = -34.725132, states[40]= 0.002038
Saving checkpoint... 
Iteration: 402228985, states[0] = -40.725523, states[40]= 0.000942
Saving checkpoint... 
Iteration: 415351802, states[0] = -94.593129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 427088583, states[0] = 10.913832, states[40]= 0.005016
Saving checkpoint... 
Iteration: 437296084, states[0] = -83.560929, states[40]= 0.000001
Saving checkpoint... 
Iteration: 450281012, states[0] = -66.227825, states[40]= 0.000015
Saving checkpoint... 
Iteration: 463294809, states[0] = -81.664091, states[40]= 0.000001
Saving checkpoint... 
Iteration: 476321522, states[0] = -94.527641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 489249366, states[0] = -49.013304, states[40]= 0.000274
Saving checkpoint... 
Iteration: 502266165, states[0] = -56.908673, states[40]= 0.000073
Saving checkpoint... 
Iteration: 515361128, states[0] = -94.606028, states[40]= 0.000000
Saving checkpoint... 
Iteration: 528533632, states[0] = 27.842346, states[40]= 0.002470
Saving checkpoint... 
Iteration: 541715580, states[0] = -35.822579, states[40]= 0.001784
Saving checkpoint... 
Iteration: 554756016, states[0] = -51.975357, states[40]= 0.000169
Saving checkpoint... 
Iteration: 567831782, states[0] = -94.559437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 580877319, states[0] = -94.625961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 593891438, states[0] = -94.640927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 606866772, states[0] = -94.613169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 619871605, states[0] = -94.619134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 632816565, states[0] = -94.471658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 643750980, states[0] = -49.717501, states[40]= 0.000245
Saving checkpoint... 
Iteration: 656738846, states[0] = -44.601477, states[40]= 0.000542
Saving checkpoint... 
Iteration: 669772332, states[0] = -60.329399, states[40]= 0.000040
Saving checkpoint... 
Iteration: 682836764, states[0] = -94.568303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 695912896, states[0] = -94.659650, states[40]= 0.000000
Saving checkpoint... 
Iteration: 707617128, states[0] = 0.362168, states[40]= 0.004754
Saving checkpoint... 
Iteration: 719261286, states[0] = -54.456406, states[40]= 0.000111
Saving checkpoint... 
Iteration: 732301060, states[0] = -90.039633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 745343216, states[0] = -94.578944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 758407366, states[0] = -94.654975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 771522724, states[0] = 30.259891, states[40]= 0.002758
Saving checkpoint... 
Iteration: 784573019, states[0] = 16.144101, states[40]= 0.004575
Saving checkpoint... 
Iteration: 797602264, states[0] = 6.021337, states[40]= 0.005099
Saving checkpoint... 
Iteration: 810666870, states[0] = -20.376813, states[40]= 0.004611
Saving checkpoint... 
Iteration: 823694495, states[0] = -28.859748, states[40]= 0.003751
Saving checkpoint... 
Iteration: 836763296, states[0] = -55.444494, states[40]= 0.000094
Saving checkpoint... 
Iteration: 849798347, states[0] = -86.803814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 862804460, states[0] = -92.572980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 875953957, states[0] = -94.685731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 889077952, states[0] = 14.530309, states[40]= 0.004756
Saving checkpoint... 
Iteration: 902136542, states[0] = -7.948134, states[40]= 0.003213
Saving checkpoint... 
Iteration: 915321373, states[0] = -94.525494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 928428026, states[0] = -94.670112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 941482192, states[0] = -94.698388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 954419920, states[0] = -94.664307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 967425968, states[0] = -94.668594, states[40]= 0.000000
Saving checkpoint... 
Iteration: 980438235, states[0] = -94.676550, states[40]= 0.000000
Saving checkpoint... 
Iteration: 993543269, states[0] = 25.125439, states[40]= 0.002897
Saving checkpoint... 
Iteration: 1006626898, states[0] = -3.670228, states[40]= 0.004114
Saving checkpoint... 
Iteration: 1019590270, states[0] = 10.325141, states[40]= 0.005042
Saving checkpoint... 
Iteration: 1032490353, states[0] = -94.701220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1045387656, states[0] = -94.635882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1058512207, states[0] = 30.644281, states[40]= 0.022661
Saving checkpoint... 
Iteration: 1071601962, states[0] = 6.132477, states[40]= 0.005101
Saving checkpoint... 
Iteration: 1084628079, states[0] = -4.179198, states[40]= 0.004012
Saving checkpoint... 
Iteration: 1097682684, states[0] = -25.258499, states[40]= 0.004703
Saving checkpoint... 
Iteration: 1110769002, states[0] = -58.425111, states[40]= 0.000056
Saving checkpoint... 
Iteration: 1123895247, states[0] = -94.643160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1136849459, states[0] = -94.587629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1149930302, states[0] = -94.671031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1163065574, states[0] = 18.495350, states[40]= 0.004227
Saving checkpoint... 
Iteration: 1176223924, states[0] = -38.824555, states[40]= 0.001216
Saving checkpoint... 
Iteration: 1189384322, states[0] = -94.632005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1202404850, states[0] = -94.651622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1215385222, states[0] = -94.632885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1228483142, states[0] = -94.697975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1241598871, states[0] = 7.259455, states[40]= 0.005106
Saving checkpoint... 
Iteration: 1254648983, states[0] = -13.572450, states[40]= 0.002579
Saving checkpoint... 
Iteration: 1267647761, states[0] = -13.035354, states[40]= 0.002570
Saving checkpoint... 
Iteration: 1280644536, states[0] = -11.591996, states[40]= 0.002639
Saving checkpoint... 
Iteration: 1293711518, states[0] = -34.412930, states[40]= 0.002115
Saving checkpoint... 
Iteration: 1306685797, states[0] = -26.196518, states[40]= 0.004501
Saving checkpoint... 
Iteration: 1319277476, states[0] = -63.611988, states[40]= 0.000023
Saving checkpoint... 
Iteration: 1332231365, states[0] = -41.636612, states[40]= 0.000830
Saving checkpoint... 
Iteration: 1345346320, states[0] = -94.582224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1355256482, states[0] = -52.186451, states[40]= 0.000163
Saving checkpoint... 
Iteration: 1364367131, states[0] = -94.611544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1377298748, states[0] = -87.330922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1390230472, states[0] = -41.291978, states[40]= 0.000871
Saving checkpoint... 
Iteration: 1403313100, states[0] = -94.356079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1414992654, states[0] = -94.700999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1428029550, states[0] = 28.880653, states[40]= 0.002380
Saving checkpoint... 
Iteration: 1441075725, states[0] = 15.264908, states[40]= 0.004679
Saving checkpoint... 
Iteration: 1454165098, states[0] = -19.790325, states[40]= 0.004411
Saving checkpoint... 
Iteration: 1467233822, states[0] = -42.594167, states[40]= 0.000725
Saving checkpoint... 
Iteration: 1480309578, states[0] = -94.050561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1493325582, states[0] = -94.542106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1506358127, states[0] = 25.876892, states[40]= 0.085473
Saving checkpoint... 
Iteration: 1519353212, states[0] = -23.116872, states[40]= 0.006619
Saving checkpoint... 
Iteration: 1532284084, states[0] = 27.728803, states[40]= 0.001735
Saving checkpoint... 
Iteration: 1545259365, states[0] = 28.932701, states[40]= 0.057190
Saving checkpoint... 
Iteration: 1558202690, states[0] = -22.219076, states[40]= 0.006018
Saving checkpoint... 
Iteration: 1571199009, states[0] = -21.235232, states[40]= 0.005829
Saving checkpoint... 
Iteration: 1584289187, states[0] = -94.421800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1597360993, states[0] = -94.423874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1610296096, states[0] = -35.790037, states[40]= 0.001936
Saving checkpoint... 
Iteration: 1623349837, states[0] = -94.356432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1636286124, states[0] = -94.353358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1649156946, states[0] = -94.345678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1662079559, states[0] = -94.339534, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1674915687, states[0] = -94.335992, states[40]= 0.000000
Total time: 3360000.000000
State Variables:
 - v in component membrane (millivolt): -94.211160
 - CaMKt in component CaMK (millimolar): 0.001256
 - cass in component intracellular_ions (millimolar): 0.000083
 - nai in component intracellular_ions (millimolar): 6.110199
 - nass in component intracellular_ions (millimolar): 6.110275
 - ki in component intracellular_ions (millimolar): 145.811558
 - kss in component intracellular_ions (millimolar): 145.811551
 - cansr in component intracellular_ions (millimolar): 1.492585
 - cajsr in component intracellular_ions (millimolar): 1.492098
 - cai in component intracellular_ions (millimolar): 0.000086
 - m in component INa (dimensionless): 0.003880
 - hf in component INa (dimensionless): 0.867488
 - hs in component INa (dimensionless): 0.867489
 - j in component INa (dimensionless): 0.867490
 - hsp in component INa (dimensionless): 0.702704
 - jp in component INa (dimensionless): 0.867491
 - mL in component INaL (dimensionless): 0.000057
 - hL in component INaL (dimensionless): 0.710585
 - hLp in component INaL (dimensionless): 0.517187
 - a in component Ito (dimensionless): 0.000653
 - iF in component Ito (dimensionless): 0.999853
 - iS in component Ito (dimensionless): 0.996009
 - ap in component Ito (dimensionless): 0.000333
 - iFp in component Ito (dimensionless): 0.999853
 - iSp in component Ito (dimensionless): 0.998556
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.997686
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002522
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.003473
 - xs1 in component IKs (dimensionless): 0.035467
 - xs2 in component IKs (dimensionless): 0.000095
 - xk1 in component IK1 (dimensionless): 0.997513
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
13:24:56 (12616): called boinc_finish(0)

</stderr_txt>
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