𝕏

Task 55395630

Name HuVeMOp_20240630064555304022_ORdGradInc_k_25-Drouin_MID_6000-conf_239_1
Workunit 26304767
Created 30 Jun 2024, 4:47:38 UTC
Sent 30 Jun 2024, 6:46:04 UTC
Report deadline 3 Jul 2024, 6:46:04 UTC
Received 1 Jul 2024, 20:31:29 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241050
Run time 2 hours 59 min 35 sec
CPU time 1 hours 29 min 25 sec
Validate state Valid
Credit 44.29
Device peak FLOPS 6.58 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.38 MB
Peak swap size 3.69 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.16.16</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064555304022_ORdGradInc_k_25-Drouin_MID_6000-conf_239.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064555304022_ORdGradInc_k_25-Drouin_MID_6000-conf_239_1_r388496069_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064555304022_ORdGradInc_k_25-Drouin_MID_6000-conf_239_1_r388496069_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 106.934939
     * GNaL_b in INaL: 0.006560
     * Gto_b in Ito: 0.081924
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031873
     * GKs_b in IKs: 0.001792
     * GK1_b in IK1: 0.154009
     * Gncx_b in INaCa_i: 0.000963
     * Pnak_b in INaK: 72.791545
     * GKb_b in IKb: 0.003751
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.049812
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 500.000000
     * CL_0 in membrane: 6000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 8383734, states[0] = -94.156087, states[40]= 0.000000
Saving checkpoint... 
Iteration: 16460956, states[0] = -94.144897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 26662676, states[0] = -94.127843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 33712895, states[0] = -94.156536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 41951508, states[0] = -94.134654, states[40]= 0.000001
Saving checkpoint... 
Iteration: 50744627, states[0] = -94.141276, states[40]= 0.000001
Saving checkpoint... 
Iteration: 58695048, states[0] = -94.157300, states[40]= 0.000001
Saving checkpoint... 
Iteration: 67342217, states[0] = -94.170684, states[40]= 0.000001
Saving checkpoint... 
Iteration: 74915469, states[0] = -94.154377, states[40]= 0.000001
Saving checkpoint... 
Iteration: 81875973, states[0] = -94.190315, states[40]= 0.000001
Saving checkpoint... 
Iteration: 89790390, states[0] = -94.160666, states[40]= 0.000001
Saving checkpoint... 
Iteration: 98348033, states[0] = -94.165699, states[40]= 0.000001
Saving checkpoint... 
Iteration: 107037789, states[0] = -94.170867, states[40]= 0.000001
Saving checkpoint... 
Iteration: 114534138, states[0] = -94.143013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 124418356, states[0] = -94.185520, states[40]= 0.000001
Saving checkpoint... 
Iteration: 132535050, states[0] = -94.146588, states[40]= 0.000000
Saving checkpoint... 
Iteration: 141556939, states[0] = -94.159238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 150350927, states[0] = -93.846251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 158088138, states[0] = -94.176647, states[40]= 0.000001
Saving checkpoint... 
Iteration: 166062683, states[0] = -94.199977, states[40]= 0.000001
Saving checkpoint... 
Iteration: 175427757, states[0] = -94.189257, states[40]= 0.000001
Saving checkpoint... 
Iteration: 183139381, states[0] = 2.910474, states[40]= 0.000158
Saving checkpoint... 
Iteration: 190116153, states[0] = -94.199069, states[40]= 0.000001
Saving checkpoint... 
Iteration: 198092768, states[0] = 19.403415, states[40]= 0.000003
Saving checkpoint... 
Iteration: 206208153, states[0] = -94.176966, states[40]= 0.000001
Saving checkpoint... 
Iteration: 214427566, states[0] = -94.190064, states[40]= 0.000001
Saving checkpoint... 
Iteration: 222432166, states[0] = -94.049236, states[40]= 0.000000
Saving checkpoint... 
Iteration: 230495601, states[0] = -94.175009, states[40]= 0.000001
Saving checkpoint... 
Iteration: 238760813, states[0] = -94.183010, states[40]= 0.000001
Saving checkpoint... 
Iteration: 247581142, states[0] = -94.186529, states[40]= 0.000001
Saving checkpoint... 
Iteration: 255455012, states[0] = -94.081447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 263626761, states[0] = -94.174346, states[40]= 0.000001
Saving checkpoint... 
Iteration: 272027979, states[0] = -94.179106, states[40]= 0.000001
Saving checkpoint... 
Iteration: 281020723, states[0] = -94.179168, states[40]= 0.000001
Saving checkpoint... 
Iteration: 289513646, states[0] = -94.187981, states[40]= 0.000001
Saving checkpoint... 
Iteration: 297032293, states[0] = 34.525544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 304817866, states[0] = -94.181922, states[40]= 0.000001
Saving checkpoint... 
Iteration: 313250331, states[0] = -94.195106, states[40]= 0.000001
Saving checkpoint... 
Iteration: 321121408, states[0] = 9.205324, states[40]= 0.000041
Saving checkpoint... 
Iteration: 328938566, states[0] = -94.180011, states[40]= 0.000001
Saving checkpoint... 
Iteration: 337434198, states[0] = -94.189722, states[40]= 0.000001
Saving checkpoint... 
Iteration: 345521975, states[0] = -94.142717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 354960208, states[0] = -94.203774, states[40]= 0.000001
Saving checkpoint... 
Iteration: 363577379, states[0] = -94.170922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 372454256, states[0] = -94.080039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 381395146, states[0] = -93.978672, states[40]= 0.000000
Saving checkpoint... 
Iteration: 388847703, states[0] = -94.180985, states[40]= 0.000001
Saving checkpoint... 
Iteration: 396749718, states[0] = -94.202427, states[40]= 0.000001
Saving checkpoint... 
Iteration: 404930361, states[0] = -94.172560, states[40]= 0.000001
Saving checkpoint... 
Iteration: 414327006, states[0] = -93.754108, states[40]= 0.000000
Saving checkpoint... 
Iteration: 422063415, states[0] = -94.177898, states[40]= 0.000001
Saving checkpoint... 
Iteration: 429724185, states[0] = -94.200443, states[40]= 0.000001
Saving checkpoint... 
Iteration: 438572799, states[0] = -94.168649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 447118290, states[0] = 10.301343, states[40]= 0.000032
Saving checkpoint... 
Iteration: 455245310, states[0] = -94.175858, states[40]= 0.000001
Saving checkpoint... 
Iteration: 463720559, states[0] = -94.182663, states[40]= 0.000001
Saving checkpoint... 
Iteration: 471233932, states[0] = -36.662302, states[40]= 0.002770
Saving checkpoint... 
Iteration: 479220015, states[0] = -94.175936, states[40]= 0.000001
Saving checkpoint... 
Iteration: 486593692, states[0] = -94.176035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 494593185, states[0] = -94.173253, states[40]= 0.000001
Saving checkpoint... 
Iteration: 503293188, states[0] = -94.175153, states[40]= 0.000001
Saving checkpoint... 
Iteration: 511690873, states[0] = -94.182918, states[40]= 0.000001
Saving checkpoint... 
Iteration: 519119756, states[0] = 9.785456, states[40]= 0.000036
Saving checkpoint... 
Iteration: 528664602, states[0] = -94.192720, states[40]= 0.000001
Saving checkpoint... 
Iteration: 536755683, states[0] = -94.172285, states[40]= 0.000001
Saving checkpoint... 
Iteration: 544788842, states[0] = -94.180966, states[40]= 0.000001
Saving checkpoint... 
Iteration: 553051266, states[0] = -94.200014, states[40]= 0.000001
Saving checkpoint... 
Iteration: 561495754, states[0] = -94.121842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 569394306, states[0] = -94.173974, states[40]= 0.000001
Saving checkpoint... 
Iteration: 577875357, states[0] = -94.179395, states[40]= 0.000001
Saving checkpoint... 
Iteration: 587012988, states[0] = -94.177472, states[40]= 0.000001
Saving checkpoint... 
Iteration: 595840970, states[0] = -94.179806, states[40]= 0.000001
Saving checkpoint... 
Iteration: 604424418, states[0] = -94.188342, states[40]= 0.000001
Saving checkpoint... 
Iteration: 612475097, states[0] = -94.102276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 621068384, states[0] = 27.685779, states[40]= 0.000000
Saving checkpoint... 
Iteration: 628847789, states[0] = -94.179495, states[40]= 0.000001
Saving checkpoint... 
Iteration: 636268547, states[0] = -62.170823, states[40]= 0.000074
Saving checkpoint... 
Iteration: 645046374, states[0] = 33.258266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 653546490, states[0] = -94.172506, states[40]= 0.000001
Saving checkpoint... 
Iteration: 662528044, states[0] = -94.172552, states[40]= 0.000001
Saving checkpoint... 
Iteration: 672589065, states[0] = -94.173304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 683360376, states[0] = -94.173507, states[40]= 0.000001
Saving checkpoint... 
Iteration: 690849083, states[0] = -94.203178, states[40]= 0.000001
Saving checkpoint... 
Iteration: 699799522, states[0] = -94.202533, states[40]= 0.000001
Saving checkpoint... 
Iteration: 708917574, states[0] = -94.202468, states[40]= 0.000001
Saving checkpoint... 
Iteration: 717499831, states[0] = -94.124235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 725961868, states[0] = -94.170484, states[40]= 0.000001
Saving checkpoint... 
Iteration: 734230598, states[0] = -94.174250, states[40]= 0.000001
Saving checkpoint... 
Iteration: 741937380, states[0] = -94.201890, states[40]= 0.000001
Saving checkpoint... 
Iteration: 750106870, states[0] = 14.349879, states[40]= 0.000012
Saving checkpoint... 
Iteration: 759158172, states[0] = -4.734162, states[40]= 0.000437
Saving checkpoint... 
Iteration: 768180607, states[0] = -16.475827, states[40]= 0.001018
Saving checkpoint... 
Iteration: 776603376, states[0] = -94.171443, states[40]= 0.000001
Saving checkpoint... 
Iteration: 785023491, states[0] = -94.176109, states[40]= 0.000001
Saving checkpoint... 
Iteration: 793552847, states[0] = -94.184027, states[40]= 0.000001
Saving checkpoint... 
Iteration: 802628710, states[0] = -94.182334, states[40]= 0.000001
Saving checkpoint... 
Iteration: 811480571, states[0] = -94.185622, states[40]= 0.000001
Saving checkpoint... 
Iteration: 819616723, states[0] = -94.180815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 827713970, states[0] = -94.170631, states[40]= 0.000001
Saving checkpoint... 
Iteration: 836438748, states[0] = -94.172008, states[40]= 0.000001
Saving checkpoint... 
Iteration: 845128655, states[0] = -94.174548, states[40]= 0.000001
Saving checkpoint... 
Iteration: 853619983, states[0] = -94.182197, states[40]= 0.000001
Saving checkpoint... 
Iteration: 862898901, states[0] = -94.177273, states[40]= 0.000001
Saving checkpoint... 
Iteration: 870969579, states[0] = -94.200353, states[40]= 0.000001
Saving checkpoint... 
Iteration: 880031306, states[0] = -94.198586, states[40]= 0.000001
Saving checkpoint... 
Iteration: 888553764, states[0] = -94.157377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 896515113, states[0] = -94.171166, states[40]= 0.000001
Saving checkpoint... 
Iteration: 906185655, states[0] = -18.642599, states[40]= 0.001741
Saving checkpoint... 
Iteration: 915183978, states[0] = -17.976350, states[40]= 0.001451
Saving checkpoint... 
Iteration: 923863193, states[0] = -94.169512, states[40]= 0.000001
Saving checkpoint... 
Iteration: 932390979, states[0] = -94.171733, states[40]= 0.000001
Saving checkpoint... 
Iteration: 940690687, states[0] = -94.180248, states[40]= 0.000001
Saving checkpoint... 
Iteration: 949284774, states[0] = -94.190143, states[40]= 0.000001
Saving checkpoint... 
Iteration: 958369994, states[0] = -94.187611, states[40]= 0.000001
Saving checkpoint... 
Iteration: 966718786, states[0] = -94.196644, states[40]= 0.000001
Saving checkpoint... 
Iteration: 974962477, states[0] = -94.168929, states[40]= 0.000001
Saving checkpoint... 
Iteration: 983565958, states[0] = -94.170343, states[40]= 0.000001
Saving checkpoint... 
Iteration: 993337530, states[0] = -93.795601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1002527739, states[0] = -94.142319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1011470572, states[0] = -94.095019, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1019357797, states[0] = -94.171430, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1029669989, states[0] = -94.190455, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1038227304, states[0] = -32.907019, states[40]= 0.004042
Saving checkpoint... 
Iteration: 1047570415, states[0] = -94.163873, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1058505215, states[0] = -94.170213, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1067418057, states[0] = -94.170705, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1077098195, states[0] = 17.448328, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1085278734, states[0] = -94.171643, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1093982418, states[0] = -94.174695, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1102704533, states[0] = -94.178978, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1112354629, states[0] = -94.170874, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1122324979, states[0] = -93.740328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1131306214, states[0] = -93.627175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1139640449, states[0] = -94.169002, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1148047843, states[0] = -94.173555, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1156092945, states[0] = -94.194947, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1164024623, states[0] = 34.096163, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1173736220, states[0] = -94.196733, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1180963674, states[0] = -94.174397, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1188691666, states[0] = -94.192440, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1196795426, states[0] = -94.168025, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1204194921, states[0] = -94.191356, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1212864584, states[0] = -94.199912, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1222055792, states[0] = -94.195710, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1229488074, states[0] = -94.169248, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1236632799, states[0] = -94.182163, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1244425413, states[0] = -94.169551, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1252445944, states[0] = -94.183746, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1260298070, states[0] = -93.270162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1270138211, states[0] = -94.192775, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1277883443, states[0] = -94.167244, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1286483400, states[0] = -94.168920, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1294861624, states[0] = -94.175131, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1302532088, states[0] = -94.143094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1310257690, states[0] = -94.170419, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1318465122, states[0] = -94.182848, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1326831178, states[0] = -94.199134, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1334423808, states[0] = -94.169000, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1342092324, states[0] = -94.193809, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1351082807, states[0] = -94.194057, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1358743947, states[0] = -94.167200, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1367207536, states[0] = -94.170514, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1375417764, states[0] = -94.183715, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1383666756, states[0] = -94.187744, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1391486337, states[0] = -94.168247, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1399469459, states[0] = -94.182235, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1408031384, states[0] = -94.195298, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1417062081, states[0] = -94.194301, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1425571937, states[0] = -94.162141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1433878792, states[0] = -94.166284, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1441897612, states[0] = -94.173682, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1450058628, states[0] = -94.194203, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1459240823, states[0] = -94.188317, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1467819189, states[0] = -94.198123, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1475788777, states[0] = -94.166307, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1484013235, states[0] = -94.171875, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1492588698, states[0] = -94.178878, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.041548
 - CaMKt in component CaMK (millimolar): 0.001325
 - cass in component intracellular_ions (millimolar): 0.000094
 - nai in component intracellular_ions (millimolar): 7.591871
 - nass in component intracellular_ions (millimolar): 7.592016
 - ki in component intracellular_ions (millimolar): 144.255276
 - kss in component intracellular_ions (millimolar): 144.255263
 - cansr in component intracellular_ions (millimolar): 1.740410
 - cajsr in component intracellular_ions (millimolar): 1.741521
 - cai in component intracellular_ions (millimolar): 0.000099
 - m in component INa (dimensionless): 0.003947
 - hf in component INa (dimensionless): 0.864252
 - hs in component INa (dimensionless): 0.864252
 - j in component INa (dimensionless): 0.864252
 - hsp in component INa (dimensionless): 0.696848
 - jp in component INa (dimensionless): 0.864253
 - mL in component INaL (dimensionless): 0.000058
 - hL in component INaL (dimensionless): 0.705892
 - hLp in component INaL (dimensionless): 0.511877
 - a in component Ito (dimensionless): 0.000661
 - iF in component Ito (dimensionless): 0.999848
 - iS in component Ito (dimensionless): 0.999120
 - ap in component Ito (dimensionless): 0.000337
 - iFp in component Ito (dimensionless): 0.999848
 - iSp in component Ito (dimensionless): 0.999675
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.999252
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004041
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.000665
 - xs1 in component IKs (dimensionless): 0.020115
 - xs2 in component IKs (dimensionless): 0.000097
 - xk1 in component IK1 (dimensionless): 0.997554
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
21:04:50 (32787): called boinc_finish(0)

</stderr_txt>
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