𝕏

Task 55395628

Name HuVeMOp_20240630064555304022_ORdGradInc_k_25-Drouin_EPI_3000-conf_339_1
Workunit 26304766
Created 30 Jun 2024, 4:47:38 UTC
Sent 30 Jun 2024, 6:46:04 UTC
Report deadline 3 Jul 2024, 6:46:04 UTC
Received 1 Jul 2024, 22:56:58 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241050
Run time 3 hours 2 min 35 sec
CPU time 1 hours 29 min 41 sec
Validate state Valid
Credit 44.86
Device peak FLOPS 6.58 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.38 MB
Peak swap size 3.69 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.16.16</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064555304022_ORdGradInc_k_25-Drouin_EPI_3000-conf_339.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064555304022_ORdGradInc_k_25-Drouin_EPI_3000-conf_339_1_r1208288303_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064555304022_ORdGradInc_k_25-Drouin_EPI_3000-conf_339_1_r1208288303_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.885673
     * GNaL_b in INaL: 0.006020
     * Gto_b in Ito: 0.095917
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033554
     * GKs_b in IKs: 0.001913
     * GK1_b in IK1: 0.147359
     * Gncx_b in INaCa_i: 0.000960
     * Pnak_b in INaK: 74.252925
     * GKb_b in IKb: 0.003819
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.028720
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 1000.000000
     * CL_0 in membrane: 3000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 7967822, states[0] = -94.242327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 15680409, states[0] = -94.208019, states[40]= 0.000000
Saving checkpoint... 
Iteration: 23700965, states[0] = -94.152320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 32228458, states[0] = -94.155384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 40838791, states[0] = -93.996572, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48589049, states[0] = -94.147229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 57325507, states[0] = -93.969681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 65451833, states[0] = -94.141426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 73477413, states[0] = -94.120500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 81607535, states[0] = -94.160254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 89610530, states[0] = -94.141769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 99554990, states[0] = -94.161325, states[40]= 0.000000
Saving checkpoint... 
Iteration: 109061966, states[0] = -94.149261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 117439393, states[0] = -94.128363, states[40]= 0.000000
Saving checkpoint... 
Iteration: 125906866, states[0] = -94.136303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 134763133, states[0] = -94.142995, states[40]= 0.000000
Saving checkpoint... 
Iteration: 143811059, states[0] = -94.141660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 151674376, states[0] = -81.811013, states[40]= 0.000001
Saving checkpoint... 
Iteration: 159339188, states[0] = -94.019775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 168140796, states[0] = -39.664598, states[40]= 0.000288
Saving checkpoint... 
Iteration: 175554298, states[0] = 22.956514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 184799320, states[0] = -93.923358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 192530633, states[0] = -94.165057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 201201431, states[0] = -93.353306, states[40]= 0.000000
Saving checkpoint... 
Iteration: 209357565, states[0] = -94.166437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 217505994, states[0] = 15.784076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 224823955, states[0] = -94.142240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 233001567, states[0] = -94.158064, states[40]= 0.000000
Saving checkpoint... 
Iteration: 241599530, states[0] = 2.601303, states[40]= 0.000155
Saving checkpoint... 
Iteration: 249402564, states[0] = -94.104668, states[40]= 0.000000
Saving checkpoint... 
Iteration: 257537528, states[0] = -94.155471, states[40]= 0.000000
Saving checkpoint... 
Iteration: 266277217, states[0] = -94.170058, states[40]= 0.000000
Saving checkpoint... 
Iteration: 274555855, states[0] = 22.562685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 282812621, states[0] = -94.167940, states[40]= 0.000000
Saving checkpoint... 
Iteration: 291068863, states[0] = 18.390780, states[40]= 0.000004
Saving checkpoint... 
Iteration: 298965996, states[0] = -94.144532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 307577206, states[0] = 14.893995, states[40]= 0.000012
Saving checkpoint... 
Iteration: 315007896, states[0] = 18.255407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 322501012, states[0] = 42.330115, states[40]= 0.516628
Saving checkpoint... 
Iteration: 330921750, states[0] = -94.160787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 338765151, states[0] = -94.142793, states[40]= 0.000000
Saving checkpoint... 
Iteration: 347236809, states[0] = -94.170388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 355561656, states[0] = 20.908995, states[40]= 0.000001
Saving checkpoint... 
Iteration: 364318610, states[0] = -94.140057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 372951452, states[0] = -94.158258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 379965105, states[0] = -94.142626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 388091709, states[0] = -94.150169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 396856634, states[0] = -94.163341, states[40]= 0.000000
Saving checkpoint... 
Iteration: 404657518, states[0] = -94.146521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 412641029, states[0] = -40.024189, states[40]= 0.000280
Saving checkpoint... 
Iteration: 420109756, states[0] = -5.438537, states[40]= 0.000303
Saving checkpoint... 
Iteration: 427100223, states[0] = -94.148985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 434653731, states[0] = -94.146133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 443553876, states[0] = -94.151134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 451639369, states[0] = -38.036034, states[40]= 0.000326
Saving checkpoint... 
Iteration: 460589022, states[0] = 8.977366, states[40]= 0.000052
Saving checkpoint... 
Iteration: 468946142, states[0] = -94.156739, states[40]= 0.000000
Saving checkpoint... 
Iteration: 476356305, states[0] = -94.161844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 485472295, states[0] = -94.154908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 494851838, states[0] = -94.136240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 503670364, states[0] = -94.144007, states[40]= 0.000000
Saving checkpoint... 
Iteration: 512624850, states[0] = -94.146089, states[40]= 0.000000
Saving checkpoint... 
Iteration: 520694941, states[0] = -93.239477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 529129514, states[0] = -94.145537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 538375380, states[0] = -94.134492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 545882572, states[0] = -94.134074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 554119031, states[0] = -94.167668, states[40]= 0.000000
Saving checkpoint... 
Iteration: 562315767, states[0] = -94.136395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 570525041, states[0] = -94.157454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 578912078, states[0] = -94.132343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 586780023, states[0] = -93.849782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 595127970, states[0] = -94.144363, states[40]= 0.000000
Saving checkpoint... 
Iteration: 603113616, states[0] = -9.211960, states[40]= 0.000316
Saving checkpoint... 
Iteration: 611959289, states[0] = -94.130039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 619804718, states[0] = -93.931871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 627942089, states[0] = -94.153961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 635912151, states[0] = -94.131267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 643381108, states[0] = -94.132282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 651440586, states[0] = -94.125036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 660052950, states[0] = 23.255338, states[40]= 0.000000
Saving checkpoint... 
Iteration: 668091475, states[0] = -94.164131, states[40]= 0.000000
Saving checkpoint... 
Iteration: 676175346, states[0] = -94.140483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 683459273, states[0] = -94.151902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 691786709, states[0] = -93.872679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 699368684, states[0] = -94.058579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 707188843, states[0] = -94.165020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 715965945, states[0] = -94.136599, states[40]= 0.000000
Saving checkpoint... 
Iteration: 723864172, states[0] = -94.156688, states[40]= 0.000000
Saving checkpoint... 
Iteration: 731898695, states[0] = -94.129927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 739407108, states[0] = -94.129471, states[40]= 0.000000
Saving checkpoint... 
Iteration: 747894439, states[0] = -94.154463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 757215400, states[0] = -94.137051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 765365847, states[0] = -94.053440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 774311391, states[0] = -93.947286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 782085254, states[0] = -94.161514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 789801940, states[0] = -94.158911, states[40]= 0.000000
Saving checkpoint... 
Iteration: 798318987, states[0] = -93.966034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 806859871, states[0] = -94.129975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 815697785, states[0] = -94.136753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 824052457, states[0] = -94.157257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 833314795, states[0] = -94.157387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 842221337, states[0] = -94.161550, states[40]= 0.000000
Saving checkpoint... 
Iteration: 850147747, states[0] = -94.138510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 858930023, states[0] = -94.150264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 867227125, states[0] = -93.556560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 875989875, states[0] = -94.123953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 884596662, states[0] = -94.140453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 893082371, states[0] = -94.159166, states[40]= 0.000000
Saving checkpoint... 
Iteration: 901280557, states[0] = -94.131409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 911087067, states[0] = -94.159188, states[40]= 0.000000
Saving checkpoint... 
Iteration: 920049562, states[0] = -94.155023, states[40]= 0.000000
Saving checkpoint... 
Iteration: 928527417, states[0] = 24.564731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 937135585, states[0] = -94.137456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 944910270, states[0] = -94.125433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 952751991, states[0] = -93.712668, states[40]= 0.000000
Saving checkpoint... 
Iteration: 961253700, states[0] = -94.131431, states[40]= 0.000000
Saving checkpoint... 
Iteration: 969969015, states[0] = -94.145870, states[40]= 0.000000
Saving checkpoint... 
Iteration: 978768805, states[0] = -94.156979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 988049463, states[0] = -94.140997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 996182058, states[0] = -90.766589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1004730375, states[0] = -94.131639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1012536015, states[0] = 25.163809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1020805974, states[0] = -94.154291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1029139570, states[0] = -38.259529, states[40]= 0.000320
Saving checkpoint... 
Iteration: 1037195304, states[0] = -94.158596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1046094413, states[0] = -94.157128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1054566252, states[0] = 19.364491, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1063478390, states[0] = -94.120755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1072623202, states[0] = -19.693270, states[40]= 0.000295
Saving checkpoint... 
Iteration: 1082407957, states[0] = -94.147290, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1090390499, states[0] = -94.123382, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1097688285, states[0] = -94.131814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1106460887, states[0] = -94.143736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1114789756, states[0] = -93.875180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1122894002, states[0] = -94.147344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1130517363, states[0] = -94.140057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1138990136, states[0] = -94.137595, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1147197939, states[0] = -94.130416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1155947187, states[0] = -94.143590, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1163780374, states[0] = -94.126401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1171541365, states[0] = 24.984051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1179591831, states[0] = -94.154411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1187544375, states[0] = -94.137466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1195481134, states[0] = -94.118137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1203887590, states[0] = -94.146173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1211688607, states[0] = -94.129632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1220236300, states[0] = -94.153806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1229827272, states[0] = -94.123200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1238766053, states[0] = -94.125602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1246982907, states[0] = -94.133117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1254619911, states[0] = -94.154385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1262421678, states[0] = -94.143067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1270387160, states[0] = -94.120084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1278868267, states[0] = -94.145881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1286944727, states[0] = -94.117662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1295805268, states[0] = -94.122844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1304187664, states[0] = -94.153685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1311916303, states[0] = -94.142443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1321287368, states[0] = -94.123112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1328652634, states[0] = -94.129145, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1336448567, states[0] = -94.116582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1344771246, states[0] = -94.149900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1353150851, states[0] = -51.953399, states[40]= 0.000082
Saving checkpoint... 
Iteration: 1361586617, states[0] = -94.131886, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1369571767, states[0] = 17.250022, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1378189691, states[0] = -94.126407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1386345780, states[0] = -94.010132, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1394158492, states[0] = -94.152291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1401933821, states[0] = -94.139696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1410392490, states[0] = -94.072926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1418664002, states[0] = -94.126870, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1426276233, states[0] = -94.121581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1434873405, states[0] = -94.142608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1443849050, states[0] = -94.143844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1450910193, states[0] = -94.088482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1458430779, states[0] = -94.103571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1466816397, states[0] = -94.119118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1475517915, states[0] = -94.133456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1484134477, states[0] = -94.150383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1491999327, states[0] = -94.134190, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.987658
 - CaMKt in component CaMK (millimolar): 0.003710
 - cass in component intracellular_ions (millimolar): 0.000102
 - nai in component intracellular_ions (millimolar): 7.155848
 - nass in component intracellular_ions (millimolar): 7.155990
 - ki in component intracellular_ions (millimolar): 144.452132
 - kss in component intracellular_ions (millimolar): 144.452113
 - cansr in component intracellular_ions (millimolar): 2.488225
 - cajsr in component intracellular_ions (millimolar): 2.489046
 - cai in component intracellular_ions (millimolar): 0.000106
 - m in component INa (dimensionless): 0.003968
 - hf in component INa (dimensionless): 0.863210
 - hs in component INa (dimensionless): 0.863212
 - j in component INa (dimensionless): 0.863220
 - hsp in component INa (dimensionless): 0.694983
 - jp in component INa (dimensionless): 0.863224
 - mL in component INaL (dimensionless): 0.000059
 - hL in component INaL (dimensionless): 0.704491
 - hLp in component INaL (dimensionless): 0.507537
 - a in component Ito (dimensionless): 0.000663
 - iF in component Ito (dimensionless): 0.999847
 - iS in component Ito (dimensionless): 0.999847
 - ap in component Ito (dimensionless): 0.000338
 - iFp in component Ito (dimensionless): 0.999847
 - iSp in component Ito (dimensionless): 0.999847
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.991379
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005457
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.024775
 - xs1 in component IKs (dimensionless): 0.068408
 - xs2 in component IKs (dimensionless): 0.000097
 - xk1 in component IK1 (dimensionless): 0.997567
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
22:20:36 (33154): called boinc_finish(0)

</stderr_txt>
]]>


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