𝕏

Task 55395022

Name HuVeMOp_20240630064555304022_ORdGradInc_k_25-Drouin_ENDO_1000-conf_431_1
Workunit 26304463
Created 30 Jun 2024, 4:47:12 UTC
Sent 30 Jun 2024, 6:46:04 UTC
Report deadline 3 Jul 2024, 6:46:04 UTC
Received 1 Jul 2024, 20:31:29 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241050
Run time 3 hours 2 min 9 sec
CPU time 1 hours 29 min 31 sec
Validate state Valid
Credit 44.21
Device peak FLOPS 6.58 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.38 MB
Peak swap size 3.69 MB
Peak disk usage 0.04 MB

Stderr output

<core_client_version>7.16.16</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064555304022_ORdGradInc_k_25-Drouin_ENDO_1000-conf_431.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064555304022_ORdGradInc_k_25-Drouin_ENDO_1000-conf_431_1_r386215228_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064555304022_ORdGradInc_k_25-Drouin_ENDO_1000-conf_431_1_r386215228_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 108.889707
     * GNaL_b in INaL: 0.005803
     * Gto_b in Ito: 0.081799
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033055
     * GKs_b in IKs: 0.001890
     * GK1_b in IK1: 0.176353
     * Gncx_b in INaCa_i: 0.000957
     * Pnak_b in INaK: 72.518232
     * GKb_b in IKb: 0.003811
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.052736
     * celltype in environment: 0.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 8022522, states[0] = 31.315411, states[40]= 0.001505
Saving checkpoint... 
Iteration: 15639797, states[0] = -44.444765, states[40]= 0.000306
Saving checkpoint... 
Iteration: 23213820, states[0] = -94.071334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 30998156, states[0] = -94.495673, states[40]= 0.000000
Saving checkpoint... 
Iteration: 39297025, states[0] = -94.336146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 46645944, states[0] = -50.456644, states[40]= 0.000159
Saving checkpoint... 
Iteration: 55530692, states[0] = 29.197746, states[40]= 0.000193
Saving checkpoint... 
Iteration: 63505519, states[0] = 33.393601, states[40]= 0.282662
Saving checkpoint... 
Iteration: 71616319, states[0] = -21.987506, states[40]= 0.001395
Saving checkpoint... 
Iteration: 81609268, states[0] = -14.945244, states[40]= 0.001714
Saving checkpoint... 
Iteration: 89864970, states[0] = -94.444380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 98125428, states[0] = -30.976265, states[40]= 0.001298
Saving checkpoint... 
Iteration: 105607027, states[0] = -12.768749, states[40]= 0.002002
Saving checkpoint... 
Iteration: 114481007, states[0] = -94.508339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 122269849, states[0] = -94.286019, states[40]= 0.000000
Saving checkpoint... 
Iteration: 131612940, states[0] = -18.895215, states[40]= 0.001403
Saving checkpoint... 
Iteration: 140016394, states[0] = 32.427697, states[40]= 0.006577
Saving checkpoint... 
Iteration: 147653515, states[0] = -59.265874, states[40]= 0.000042
Saving checkpoint... 
Iteration: 155737208, states[0] = -94.177560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 163505189, states[0] = 33.835402, states[40]= 0.318154
Saving checkpoint... 
Iteration: 171426717, states[0] = -94.489697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 178972892, states[0] = -94.507035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 187224752, states[0] = -94.124541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 195244410, states[0] = -94.205115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 202584604, states[0] = 5.006525, states[40]= 0.002889
Saving checkpoint... 
Iteration: 210850186, states[0] = -94.431737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 218757061, states[0] = -94.248397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 226787803, states[0] = -94.331100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 236689399, states[0] = -93.861406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 244834510, states[0] = -94.412380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 253144235, states[0] = -49.637452, states[40]= 0.000176
Saving checkpoint... 
Iteration: 261396492, states[0] = -94.471821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 269183692, states[0] = -93.439849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 277242577, states[0] = -94.197631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 284943940, states[0] = -94.496446, states[40]= 0.000000
Saving checkpoint... 
Iteration: 293710190, states[0] = -94.053037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 302168727, states[0] = -78.946643, states[40]= 0.000002
Saving checkpoint... 
Iteration: 310686238, states[0] = -93.709176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 319024862, states[0] = 30.878279, states[40]= 0.000440
Saving checkpoint... 
Iteration: 326869160, states[0] = -94.449815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 334742950, states[0] = -94.198486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 343065941, states[0] = 14.532103, states[40]= 0.001258
Saving checkpoint... 
Iteration: 351823491, states[0] = -94.395843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 359264315, states[0] = -94.269350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 367407293, states[0] = -94.477679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 375793910, states[0] = -94.342975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 384582656, states[0] = 6.116442, states[40]= 0.002708
Saving checkpoint... 
Iteration: 392295083, states[0] = -94.345259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 400662129, states[0] = -69.297745, states[40]= 0.000009
Saving checkpoint... 
Iteration: 409030849, states[0] = 29.046095, states[40]= 0.000183
Saving checkpoint... 
Iteration: 417173289, states[0] = -86.263995, states[40]= 0.000001
Saving checkpoint... 
Iteration: 425468740, states[0] = -94.503714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 433614658, states[0] = -20.670065, states[40]= 0.001369
Saving checkpoint... 
Iteration: 441834641, states[0] = -94.410712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 450751989, states[0] = -94.229562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 459359036, states[0] = -94.438866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 466734753, states[0] = -94.165127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 473941970, states[0] = -94.493877, states[40]= 0.000000
Saving checkpoint... 
Iteration: 482215879, states[0] = -94.079931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 489941568, states[0] = -94.493562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 497380355, states[0] = -94.457748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 505396769, states[0] = -94.469716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 513292115, states[0] = -94.337869, states[40]= 0.000000
Saving checkpoint... 
Iteration: 522104994, states[0] = -10.804349, states[40]= 0.002312
Saving checkpoint... 
Iteration: 531108076, states[0] = -13.949999, states[40]= 0.001827
Saving checkpoint... 
Iteration: 539642057, states[0] = -47.413669, states[40]= 0.000237
Saving checkpoint... 
Iteration: 548048915, states[0] = 22.037562, states[40]= 0.000455
Saving checkpoint... 
Iteration: 555846785, states[0] = -94.424682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 564018667, states[0] = 32.184804, states[40]= 0.003026
Saving checkpoint... 
Iteration: 572962989, states[0] = -94.500544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 582453528, states[0] = -94.497258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 591423421, states[0] = -94.484388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 598504238, states[0] = 36.022345, states[40]= 0.440089
Saving checkpoint... 
Iteration: 606613855, states[0] = -19.862733, states[40]= 0.001376
Saving checkpoint... 
Iteration: 614761792, states[0] = -94.259384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 622602032, states[0] = -7.897614, states[40]= 0.002804
Saving checkpoint... 
Iteration: 631351030, states[0] = -94.428769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 639762415, states[0] = -94.261024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 646900300, states[0] = -94.470700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 656316460, states[0] = -94.381983, states[40]= 0.000000
Saving checkpoint... 
Iteration: 664182288, states[0] = -93.175461, states[40]= 0.000000
Saving checkpoint... 
Iteration: 672464664, states[0] = -94.500136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 680738694, states[0] = -94.178861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 688944107, states[0] = -94.492707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 696478782, states[0] = -94.503989, states[40]= 0.000000
Saving checkpoint... 
Iteration: 705489610, states[0] = -94.506597, states[40]= 0.000000
Saving checkpoint... 
Iteration: 713032710, states[0] = 28.404765, states[40]= 0.000181
Saving checkpoint... 
Iteration: 721150311, states[0] = -55.909628, states[40]= 0.000071
Saving checkpoint... 
Iteration: 729008766, states[0] = 32.019323, states[40]= 0.092443
Saving checkpoint... 
Iteration: 737226709, states[0] = -94.128201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 745577257, states[0] = 9.019141, states[40]= 0.002193
Saving checkpoint... 
Iteration: 754400503, states[0] = -94.469815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 761751692, states[0] = -94.225579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 769904554, states[0] = -94.472217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 777876796, states[0] = -94.452187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 785594856, states[0] = -1.746838, states[40]= 0.003428
Saving checkpoint... 
Iteration: 794013407, states[0] = 32.462741, states[40]= 0.018463
Saving checkpoint... 
Iteration: 802617192, states[0] = -23.174175, states[40]= 0.001399
Saving checkpoint... 
Iteration: 812083442, states[0] = 5.675178, states[40]= 0.002782
Saving checkpoint... 
Iteration: 819773923, states[0] = -94.291706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 828270701, states[0] = -94.282980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 836791902, states[0] = -94.334335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 845129416, states[0] = -34.946635, states[40]= 0.000982
Saving checkpoint... 
Iteration: 853336932, states[0] = -94.409809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 861691354, states[0] = -93.902479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 870952509, states[0] = -94.494170, states[40]= 0.000000
Saving checkpoint... 
Iteration: 878485277, states[0] = -94.503930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 887052051, states[0] = 20.708888, states[40]= 0.000555
Saving checkpoint... 
Iteration: 894826607, states[0] = -94.395286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 903403578, states[0] = -94.470353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 912049110, states[0] = 21.956658, states[40]= 0.000460
Saving checkpoint... 
Iteration: 920084665, states[0] = 4.972778, states[40]= 0.002894
Saving checkpoint... 
Iteration: 927848865, states[0] = -94.423540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 936196388, states[0] = -93.964097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 944195323, states[0] = -93.954584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 952610080, states[0] = -16.010538, states[40]= 0.001589
Saving checkpoint... 
Iteration: 959543902, states[0] = 24.113146, states[40]= 0.000329
Saving checkpoint... 
Iteration: 967691077, states[0] = -93.895926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 975589886, states[0] = 1.757767, states[40]= 0.003296
Saving checkpoint... 
Iteration: 984352790, states[0] = -94.427353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 992842338, states[0] = -94.415264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1002155504, states[0] = -61.451655, states[40]= 0.000030
Saving checkpoint... 
Iteration: 1009908693, states[0] = -94.472441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1019083694, states[0] = 5.532774, states[40]= 0.002806
Saving checkpoint... 
Iteration: 1028207373, states[0] = -94.031160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1036821458, states[0] = -94.386260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1044772644, states[0] = -94.286166, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1053213224, states[0] = -94.061206, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1062466830, states[0] = -94.497128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1071127781, states[0] = -33.373432, states[40]= 0.001112
Saving checkpoint... 
Iteration: 1078859556, states[0] = -94.433528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1087020698, states[0] = 31.848714, states[40]= 0.001536
Saving checkpoint... 
Iteration: 1095293445, states[0] = -94.335154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1104676421, states[0] = -90.066844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1113513920, states[0] = 32.481463, states[40]= 0.015455
Saving checkpoint... 
Iteration: 1121459860, states[0] = -94.494351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1129523386, states[0] = 31.259838, states[40]= 0.000662
Saving checkpoint... 
Iteration: 1138659816, states[0] = -66.393672, states[40]= 0.000014
Saving checkpoint... 
Iteration: 1148131631, states[0] = -37.078932, states[40]= 0.000806
Saving checkpoint... 
Iteration: 1157221234, states[0] = -94.099156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1166265589, states[0] = -94.265363, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1175227470, states[0] = -94.127359, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1184712452, states[0] = -94.056035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1193684303, states[0] = -93.511543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1202514533, states[0] = 32.489526, states[40]= 0.012500
Saving checkpoint... 
Iteration: 1209756782, states[0] = -94.238088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1218036549, states[0] = 27.004290, states[40]= 0.000209
Saving checkpoint... 
Iteration: 1226626319, states[0] = -31.969613, states[40]= 0.001221
Saving checkpoint... 
Iteration: 1235229364, states[0] = -94.135060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1242949961, states[0] = -94.489727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1251395780, states[0] = -94.462001, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1259707454, states[0] = -94.029356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1267253074, states[0] = -94.225397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1275641493, states[0] = -46.831225, states[40]= 0.000256
Saving checkpoint... 
Iteration: 1283237637, states[0] = -94.168909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1290860066, states[0] = -94.432034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1299136679, states[0] = -42.009612, states[40]= 0.000470
Saving checkpoint... 
Iteration: 1307610686, states[0] = -16.629733, states[40]= 0.001534
Saving checkpoint... 
Iteration: 1315621838, states[0] = -27.670785, states[40]= 0.001434
Saving checkpoint... 
Iteration: 1324092613, states[0] = -0.096727, states[40]= 0.003413
Saving checkpoint... 
Iteration: 1332225547, states[0] = -94.117282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1340130161, states[0] = -35.657951, states[40]= 0.000922
Saving checkpoint... 
Iteration: 1347793766, states[0] = -94.333427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1355795045, states[0] = -94.336016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1364188834, states[0] = -93.830996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1372872800, states[0] = -94.443156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1381209934, states[0] = -94.041219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1389476183, states[0] = -94.496752, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1397887481, states[0] = -94.454731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1406459960, states[0] = -94.491695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1414823863, states[0] = -94.386316, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1423999061, states[0] = -94.501898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1433711263, states[0] = -94.047568, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1442215310, states[0] = -94.067869, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1450486446, states[0] = -94.498821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1459564400, states[0] = 15.247583, states[40]= 0.001157
Saving checkpoint... 
Iteration: 1468954751, states[0] = -94.489327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1477210382, states[0] = -94.042613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1486518211, states[0] = 32.248232, states[40]= 0.003531
Saving checkpoint... 
Iteration: 1495395148, states[0] = -94.459266, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.377250
 - CaMKt in component CaMK (millimolar): 0.017345
 - cass in component intracellular_ions (millimolar): 0.000097
 - nai in component intracellular_ions (millimolar): 6.994704
 - nass in component intracellular_ions (millimolar): 6.994826
 - ki in component intracellular_ions (millimolar): 144.791667
 - kss in component intracellular_ions (millimolar): 144.791648
 - cansr in component intracellular_ions (millimolar): 1.930006
 - cajsr in component intracellular_ions (millimolar): 1.886542
 - cai in component intracellular_ions (millimolar): 0.000100
 - m in component INa (dimensionless): 0.003815
 - hf in component INa (dimensionless): 0.870596
 - hs in component INa (dimensionless): 0.870587
 - j in component INa (dimensionless): 0.870529
 - hsp in component INa (dimensionless): 0.708324
 - jp in component INa (dimensionless): 0.870488
 - mL in component INaL (dimensionless): 0.000055
 - hL in component INaL (dimensionless): 0.691684
 - hLp in component INaL (dimensionless): 0.425183
 - a in component Ito (dimensionless): 0.000646
 - iF in component Ito (dimensionless): 0.999857
 - iS in component Ito (dimensionless): 0.602232
 - ap in component Ito (dimensionless): 0.000329
 - iFp in component Ito (dimensionless): 0.999857
 - iSp in component Ito (dimensionless): 0.669493
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.902758
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999774
 - jca in component ICaL (dimensionless): 0.999968
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004543
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.390833
 - xs1 in component IKs (dimensionless): 0.286285
 - xs2 in component IKs (dimensionless): 0.000093
 - xk1 in component IK1 (dimensionless): 0.997472
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
21:22:19 (32864): called boinc_finish(0)

</stderr_txt>
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