𝕏

Task 55393544

Name HuVeMOp_20240630064555304022_ORdGradInc_k_25-Drouin_MID_6000-conf_803_0
Workunit 26303725
Created 30 Jun 2024, 4:46:05 UTC
Sent 30 Jun 2024, 6:25:09 UTC
Report deadline 3 Jul 2024, 6:25:09 UTC
Received 30 Jun 2024, 9:50:41 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 239941
Run time 1 hours 56 min 43 sec
CPU time 1 hours 11 min 13 sec
Validate state Valid
Credit 43.75
Device peak FLOPS 5.16 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 2.83 MB
Peak swap size 391.76 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064555304022_ORdGradInc_k_25-Drouin_MID_6000-conf_803.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064555304022_ORdGradInc_k_25-Drouin_MID_6000-conf_803_0_r2063893369_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064555304022_ORdGradInc_k_25-Drouin_MID_6000-conf_803_0_r2063893369_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 114.304190
     * GNaL_b in INaL: 0.005694
     * Gto_b in Ito: 0.095502
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.031744
     * GKs_b in IKs: 0.001857
     * GK1_b in IK1: 0.174902
     * Gncx_b in INaCa_i: 0.000970
     * Pnak_b in INaK: 70.855445
     * GKb_b in IKb: 0.003813
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.025843
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 500.000000
     * CL_0 in membrane: 6000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 22467836, states[0] = -94.285212, states[40]= 0.000001
Saving checkpoint... 
Iteration: 52769968, states[0] = -94.301302, states[40]= 0.000001
Saving checkpoint... 
Iteration: 78823968, states[0] = -94.333280, states[40]= 0.000001
Saving checkpoint... 
Iteration: 106208501, states[0] = -94.332889, states[40]= 0.000001
Saving checkpoint... 
Iteration: 133483444, states[0] = -94.329722, states[40]= 0.000001
Saving checkpoint... 
Iteration: 159277861, states[0] = -83.164465, states[40]= 0.000004
Saving checkpoint... 
Iteration: 185418666, states[0] = -94.320959, states[40]= 0.000001
Saving checkpoint... 
Iteration: 210188968, states[0] = -20.730263, states[40]= 0.003334
Saving checkpoint... 
Iteration: 235527006, states[0] = -94.331878, states[40]= 0.000001
Saving checkpoint... 
Iteration: 259269129, states[0] = -94.337967, states[40]= 0.000001
Saving checkpoint... 
Iteration: 286400281, states[0] = -94.334540, states[40]= 0.000001
Saving checkpoint... 
Iteration: 305137804, states[0] = -94.323136, states[40]= 0.000001
Saving checkpoint... 
Iteration: 333462854, states[0] = -94.242691, states[40]= 0.000000
Saving checkpoint... 
Iteration: 356474472, states[0] = -94.320588, states[40]= 0.000001
Saving checkpoint... 
Iteration: 378911896, states[0] = -94.346390, states[40]= 0.000001
Saving checkpoint... 
Iteration: 401313900, states[0] = -94.321189, states[40]= 0.000001
Saving checkpoint... 
Iteration: 423457276, states[0] = -94.236103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 444117240, states[0] = 10.307688, states[40]= 0.000040
Saving checkpoint... 
Iteration: 466611790, states[0] = -94.328929, states[40]= 0.000001
Saving checkpoint... 
Iteration: 489385232, states[0] = -94.119726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 511901116, states[0] = -94.324214, states[40]= 0.000001
Saving checkpoint... 
Iteration: 534144739, states[0] = 0.114739, states[40]= 0.000292
Saving checkpoint... 
Iteration: 556738766, states[0] = -94.326156, states[40]= 0.000001
Saving checkpoint... 
Iteration: 579211981, states[0] = -28.036258, states[40]= 0.005938
Saving checkpoint... 
Iteration: 601968900, states[0] = -94.322789, states[40]= 0.000001
Saving checkpoint... 
Iteration: 623217519, states[0] = -94.320324, states[40]= 0.000001
Saving checkpoint... 
Iteration: 646354204, states[0] = -94.333236, states[40]= 0.000001
Saving checkpoint... 
Iteration: 668498956, states[0] = -94.318312, states[40]= 0.000001
Saving checkpoint... 
Iteration: 691082867, states[0] = -94.340331, states[40]= 0.000001
Saving checkpoint... 
Iteration: 713742677, states[0] = -94.317122, states[40]= 0.000001
Saving checkpoint... 
Iteration: 736831341, states[0] = -94.323554, states[40]= 0.000001
Saving checkpoint... 
Iteration: 759158919, states[0] = -6.223467, states[40]= 0.000539


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064555304022_ORdGradInc_k_25-Drouin_MID_6000-conf_803.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064555304022_ORdGradInc_k_25-Drouin_MID_6000-conf_803_0_r2063893369_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064555304022_ORdGradInc_k_25-Drouin_MID_6000-conf_803_0_r2063893369_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 114.304190
     * GNaL_b in INaL: 0.005694
     * Gto_b in Ito: 0.095502
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.031744
     * GKs_b in IKs: 0.001857
     * GK1_b in IK1: 0.174902
     * Gncx_b in INaCa_i: 0.000970
     * Pnak_b in INaK: 70.855445
     * GKb_b in IKb: 0.003813
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.025843
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 500.000000
     * CL_0 in membrane: 6000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 759158919
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -6.223467 (After loading)
 - states[40]: 0.000539 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 779026830, states[0] = -94.320934, states[40]= 0.000001
Saving checkpoint... 
Iteration: 804430183, states[0] = -94.199230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 824914179, states[0] = -94.315985, states[40]= 0.000001
Saving checkpoint... 
Iteration: 847736739, states[0] = -94.324161, states[40]= 0.000001
Saving checkpoint... 
Iteration: 869988499, states[0] = -94.315568, states[40]= 0.000001
Saving checkpoint... 
Iteration: 890192238, states[0] = -94.318659, states[40]= 0.000001
Saving checkpoint... 
Iteration: 911949930, states[0] = -94.315325, states[40]= 0.000001
Saving checkpoint... 
Iteration: 933634078, states[0] = -94.326885, states[40]= 0.000001
Saving checkpoint... 
Iteration: 955653052, states[0] = -94.324786, states[40]= 0.000001
Saving checkpoint... 
Iteration: 977248066, states[0] = -94.317629, states[40]= 0.000001
Saving checkpoint... 
Iteration: 998760422, states[0] = -94.315088, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1020287004, states[0] = -93.289871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1041789387, states[0] = -94.341301, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1060816000, states[0] = -94.321508, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1082836368, states[0] = -94.314328, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1104742872, states[0] = -94.338862, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1126879928, states[0] = -94.320196, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1148650896, states[0] = -94.314365, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1170404561, states[0] = -94.154648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1192397287, states[0] = -94.328386, states[40]= 0.000001


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064555304022_ORdGradInc_k_25-Drouin_MID_6000-conf_803.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064555304022_ORdGradInc_k_25-Drouin_MID_6000-conf_803_0_r2063893369_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064555304022_ORdGradInc_k_25-Drouin_MID_6000-conf_803_0_r2063893369_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 114.304190
     * GNaL_b in INaL: 0.005694
     * Gto_b in Ito: 0.095502
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.031744
     * GKs_b in IKs: 0.001857
     * GK1_b in IK1: 0.174902
     * Gncx_b in INaCa_i: 0.000970
     * Pnak_b in INaK: 70.855445
     * GKb_b in IKb: 0.003813
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.025843
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 500.000000
     * CL_0 in membrane: 6000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1192397287
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.328386 (After loading)
 - states[40]: 0.000001 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1236176506, states[0] = -15.729976, states[40]= 0.000977
Saving checkpoint... 
Iteration: 1265550572, states[0] = -94.313924, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1288651806, states[0] = -94.322489, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1311499050, states[0] = -94.267822, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064555304022_ORdGradInc_k_25-Drouin_MID_6000-conf_803.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064555304022_ORdGradInc_k_25-Drouin_MID_6000-conf_803_0_r2063893369_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064555304022_ORdGradInc_k_25-Drouin_MID_6000-conf_803_0_r2063893369_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 114.304190
     * GNaL_b in INaL: 0.005694
     * Gto_b in Ito: 0.095502
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.031744
     * GKs_b in IKs: 0.001857
     * GK1_b in IK1: 0.174902
     * Gncx_b in INaCa_i: 0.000970
     * Pnak_b in INaK: 70.855445
     * GKb_b in IKb: 0.003813
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.025843
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 500.000000
     * CL_0 in membrane: 6000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1311499050
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.267822 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1340406793, states[0] = -94.314092, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1361955317, states[0] = -94.312180, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1385063698, states[0] = -94.316343, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1408168950, states[0] = -94.332909, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1428283371, states[0] = -91.993425, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1451145153, states[0] = -94.315138, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1471787776, states[0] = -94.319046, states[40]= 0.000001


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064555304022_ORdGradInc_k_25-Drouin_MID_6000-conf_803.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064555304022_ORdGradInc_k_25-Drouin_MID_6000-conf_803_0_r2063893369_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630064555304022_ORdGradInc_k_25-Drouin_MID_6000-conf_803_0_r2063893369_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 114.304190
     * GNaL_b in INaL: 0.005694
     * Gto_b in Ito: 0.095502
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.031744
     * GKs_b in IKs: 0.001857
     * GK1_b in IK1: 0.174902
     * Gncx_b in INaCa_i: 0.000970
     * Pnak_b in INaK: 70.855445
     * GKb_b in IKb: 0.003813
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.025843
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 500.000000
     * CL_0 in membrane: 6000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1471787776
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.319046 (After loading)
 - states[40]: 0.000001 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.187141
 - CaMKt in component CaMK (millimolar): 0.001376
 - cass in component intracellular_ions (millimolar): 0.000096
 - nai in component intracellular_ions (millimolar): 7.739219
 - nass in component intracellular_ions (millimolar): 7.739370
 - ki in component intracellular_ions (millimolar): 144.094358
 - kss in component intracellular_ions (millimolar): 144.094344
 - cansr in component intracellular_ions (millimolar): 1.777264
 - cajsr in component intracellular_ions (millimolar): 1.778646
 - cai in component intracellular_ions (millimolar): 0.000101
 - m in component INa (dimensionless): 0.003889
 - hf in component INa (dimensionless): 0.867034
 - hs in component INa (dimensionless): 0.867034
 - j in component INa (dimensionless): 0.867034
 - hsp in component INa (dimensionless): 0.701878
 - jp in component INa (dimensionless): 0.867035
 - mL in component INaL (dimensionless): 0.000057
 - hL in component INaL (dimensionless): 0.709909
 - hLp in component INaL (dimensionless): 0.516723
 - a in component Ito (dimensionless): 0.000654
 - iF in component Ito (dimensionless): 0.999852
 - iS in component Ito (dimensionless): 0.999149
 - ap in component Ito (dimensionless): 0.000333
 - iFp in component Ito (dimensionless): 0.999852
 - iSp in component Ito (dimensionless): 0.999687
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.999270
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004314
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.000626
 - xs1 in component IKs (dimensionless): 0.019794
 - xs2 in component IKs (dimensionless): 0.000095
 - xk1 in component IK1 (dimensionless): 0.997519
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
10:34:25 (4113): called boinc_finish(0)

</stderr_txt>
]]>