𝕏

Task 55388884

Name HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_896_1
Workunit 26301494
Created 30 Jun 2024, 3:49:22 UTC
Sent 30 Jun 2024, 5:40:04 UTC
Report deadline 3 Jul 2024, 15:16:04 UTC
Received 1 Jul 2024, 7:35:00 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 216581
Run time 1 hours 21 min 29 sec
CPU time 1 hours 3 min 14 sec
Validate state Valid
Credit 63.17
Device peak FLOPS 5.02 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 7.52 MB
Peak swap size 1.53 MB
Peak disk usage 0.25 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_896.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_896_1_r1552384580_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_896_1_r1552384580_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 114.799662
     * GNaL_b in INaL: 0.005971
     * Gto_b in Ito: 0.075820
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033513
     * GKs_b in IKs: 0.002107
     * GK1_b in IK1: 0.167085
     * Gncx_b in INaCa_i: 0.000977
     * Pnak_b in INaK: 72.150199
     * GKb_b in IKb: 0.003703
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029755
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 9243555, states[0] = -95.098659, states[40]= 0.000000
Saving checkpoint... 
Iteration: 21002227, states[0] = 44.842088, states[40]= 0.085400
Saving checkpoint... 
Iteration: 33081762, states[0] = -8.365842, states[40]= 0.002763
Saving checkpoint... 
Iteration: 45362937, states[0] = -95.102397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 54674060, states[0] = -94.882627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 66690942, states[0] = -94.914268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 79330668, states[0] = -95.067576, states[40]= 0.000000
Saving checkpoint... 
Iteration: 91423948, states[0] = -95.096782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 103926766, states[0] = -95.094984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 112751251, states[0] = -94.997032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 122078489, states[0] = -3.887595, states[40]= 0.003691
Saving checkpoint... 
Iteration: 134084214, states[0] = -8.393079, states[40]= 0.002730
Saving checkpoint... 
Iteration: 146502162, states[0] = 45.789722, states[40]= 0.078464
Saving checkpoint... 
Iteration: 158817348, states[0] = -95.049953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 159502051, states[0] = 46.672288, states[40]= 0.073556
Saving checkpoint... 
Iteration: 169740328, states[0] = -94.980153, states[40]= 0.000000
Saving checkpoint... 
Iteration: 180288331, states[0] = -95.029320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 190871739, states[0] = -95.074664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 200867193, states[0] = -95.072899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 211122347, states[0] = -47.035285, states[40]= 0.000041
Saving checkpoint... 
Iteration: 219221870, states[0] = -94.953163, states[40]= 0.000000
Saving checkpoint... 
Iteration: 219419845, states[0] = -95.088241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 231390542, states[0] = -95.080505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 233429908, states[0] = -95.090367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 245015156, states[0] = 22.862048, states[40]= 0.019820
Saving checkpoint... 
Iteration: 256711365, states[0] = -94.935779, states[40]= 0.000000
Saving checkpoint... 
Iteration: 268382140, states[0] = -95.077790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 277401693, states[0] = -95.083559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 289321296, states[0] = -95.051173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 301466702, states[0] = -95.096719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 313948555, states[0] = -95.093784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 326417571, states[0] = -95.087494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 338338405, states[0] = -95.060222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 356084166, states[0] = -8.241336, states[40]= 0.002761
Saving checkpoint... 
Iteration: 368394461, states[0] = -95.081466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 381138445, states[0] = -66.524438, states[40]= 0.000002
Saving checkpoint... 
Iteration: 392868018, states[0] = -95.072804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 404902758, states[0] = -95.083749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 417284616, states[0] = -95.025614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 426357484, states[0] = -95.068699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 439471966, states[0] = -95.097394, states[40]= 0.000000
Saving checkpoint... 
Iteration: 451334294, states[0] = -95.058110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 463747289, states[0] = -94.987968, states[40]= 0.000000
Saving checkpoint... 
Iteration: 475646949, states[0] = -80.037090, states[40]= 0.000000
Saving checkpoint... 
Iteration: 487336595, states[0] = -95.059249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 496224076, states[0] = -94.956249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 508108487, states[0] = -32.260027, states[40]= 0.000338
Saving checkpoint... 
Iteration: 520334740, states[0] = -95.058302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 532564466, states[0] = 4.441938, states[40]= 0.004807
Saving checkpoint... 
Iteration: 544840116, states[0] = -95.060942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 555739257, states[0] = -94.977778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 568116844, states[0] = -40.960190, states[40]= 0.000104
Saving checkpoint... 
Iteration: 580415553, states[0] = -95.086884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 592286624, states[0] = -95.027172, states[40]= 0.000000
Saving checkpoint... 
Iteration: 604541513, states[0] = 14.456730, states[40]= 0.005505
Saving checkpoint... 
Iteration: 616580225, states[0] = -5.041229, states[40]= 0.003454
Saving checkpoint... 
Iteration: 626828291, states[0] = -95.054879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 638876422, states[0] = -95.075661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 651062161, states[0] = 5.561682, states[40]= 0.004885
Saving checkpoint... 
Iteration: 662904947, states[0] = -95.084197, states[40]= 0.000000
Saving checkpoint... 
Iteration: 674733086, states[0] = -94.969345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 686753735, states[0] = -94.995415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 695737905, states[0] = -94.975917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 707587300, states[0] = -11.062333, states[40]= 0.002168
Saving checkpoint... 
Iteration: 719438041, states[0] = -95.091634, states[40]= 0.000000
Saving checkpoint... 
Iteration: 731164932, states[0] = -94.714110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 743888679, states[0] = -95.079560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 755821397, states[0] = -95.050972, states[40]= 0.000000
Saving checkpoint... 
Iteration: 765062089, states[0] = 5.596049, states[40]= 0.004888
Saving checkpoint... 
Iteration: 776619173, states[0] = -43.485047, states[40]= 0.000071
Saving checkpoint... 
Iteration: 788883477, states[0] = -95.077915, states[40]= 0.000000
Saving checkpoint... 
Iteration: 800769643, states[0] = -95.012017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 812446193, states[0] = -95.093102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 824535111, states[0] = 16.915329, states[40]= 0.005983
Saving checkpoint... 
Iteration: 836611158, states[0] = -34.997544, states[40]= 0.000241
Saving checkpoint... 
Iteration: 848386436, states[0] = -95.078817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 860100184, states[0] = -23.844665, states[40]= 0.000727
Saving checkpoint... 
Iteration: 871622934, states[0] = -47.681365, states[40]= 0.000037
Saving checkpoint... 
Iteration: 883687253, states[0] = -94.889684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 895460939, states[0] = -95.095527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 907270220, states[0] = -95.012518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 919054302, states[0] = 9.135461, states[40]= 0.005084
Saving checkpoint... 
Iteration: 930812021, states[0] = -95.045228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 940487996, states[0] = -95.099236, states[40]= 0.000000
Saving checkpoint... 
Iteration: 957796816, states[0] = -95.034858, states[40]= 0.000000
Saving checkpoint... 
Iteration: 969726494, states[0] = -94.959662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 981385601, states[0] = -95.078489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 993877335, states[0] = -95.075791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1005946899, states[0] = -95.093130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1018055150, states[0] = 8.764110, states[40]= 0.005065
Saving checkpoint... 
Iteration: 1030073504, states[0] = -0.478460, states[40]= 0.004275
Saving checkpoint... 
Iteration: 1039267241, states[0] = -95.009551, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1050962027, states[0] = -95.095617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1063152904, states[0] = -89.842533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1074879474, states[0] = -95.076467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1086780985, states[0] = -95.022207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1098154947, states[0] = -91.918765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1110096035, states[0] = -19.659503, states[40]= 0.000985
Saving checkpoint... 
Iteration: 1119281571, states[0] = -95.022693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1131152464, states[0] = -89.283213, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1142719919, states[0] = -94.949434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1154578412, states[0] = -3.706632, states[40]= 0.003724
Saving checkpoint... 
Iteration: 1166208320, states[0] = -94.929943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1177749333, states[0] = -94.990056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1189562494, states[0] = 5.402485, states[40]= 0.004875
Saving checkpoint... 
Iteration: 1201019599, states[0] = 21.784938, states[40]= 0.011303
Saving checkpoint... 
Iteration: 1212616033, states[0] = -40.093464, states[40]= 0.000118
Saving checkpoint... 
Iteration: 1224583384, states[0] = -7.573292, states[40]= 0.002907
Saving checkpoint... 
Iteration: 1237035895, states[0] = 16.624704, states[40]= 0.005908
Saving checkpoint... 
Iteration: 1248529858, states[0] = 18.768238, states[40]= 0.006689
Saving checkpoint... 
Iteration: 1260335483, states[0] = -95.058301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1272710924, states[0] = -94.934440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1284420473, states[0] = -95.087669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1293484465, states[0] = -95.098622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1305347379, states[0] = -95.063930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1317090266, states[0] = -13.902774, states[40]= 0.001657
Saving checkpoint... 
Iteration: 1329089147, states[0] = -12.815851, states[40]= 0.001839
Saving checkpoint... 
Iteration: 1340825332, states[0] = -95.052899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1352656381, states[0] = -92.903332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1364430332, states[0] = -95.089766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1375970569, states[0] = -95.096721, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1387930976, states[0] = -95.089887, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1399460279, states[0] = -95.095168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1411486760, states[0] = -95.098847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1423076835, states[0] = -2.612009, states[40]= 0.003928
Saving checkpoint... 
Iteration: 1435435326, states[0] = -95.090741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1447338729, states[0] = -95.059813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1456114692, states[0] = -38.674002, states[40]= 0.000145
Saving checkpoint... 
Iteration: 1468301895, states[0] = -95.038233, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1480032310, states[0] = 17.925361, states[40]= 0.006310
Saving checkpoint... 
Iteration: 1491810096, states[0] = -95.043716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1503826675, states[0] = -95.254196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1515508922, states[0] = -95.241846, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1527361364, states[0] = 0.162652, states[40]= 0.004858
Saving checkpoint... 
Iteration: 1538999191, states[0] = -95.352388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1551183823, states[0] = -95.224089, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1562684325, states[0] = -95.353790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1574333146, states[0] = -95.309814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1586257847, states[0] = -95.172353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1598150475, states[0] = 6.464851, states[40]= 0.005648
Saving checkpoint... 
Iteration: 1610144846, states[0] = 9.634332, states[40]= 0.005989
Saving checkpoint... 
Iteration: 1622230213, states[0] = -87.890924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1631201981, states[0] = -45.001795, states[40]= 0.000059
Saving checkpoint... 
Iteration: 1643511595, states[0] = -57.442291, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1655826724, states[0] = -81.611670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1667565223, states[0] = -95.196065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1679551677, states[0] = -95.153528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1691446444, states[0] = 8.716381, states[40]= 0.005888
Saving checkpoint... 
Iteration: 1703632376, states[0] = -95.315333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1715453326, states[0] = 4.691790, states[40]= 0.005469
Saving checkpoint... 
Iteration: 1727489999, states[0] = -30.846535, states[40]= 0.000397
Saving checkpoint... 
Iteration: 1739769722, states[0] = -7.932468, states[40]= 0.003170
Saving checkpoint... 
Iteration: 1751705912, states[0] = 29.645249, states[40]= 0.105922
Saving checkpoint... 
Iteration: 1763430014, states[0] = 17.077747, states[40]= 0.007637
Saving checkpoint... 
Iteration: 1775902930, states[0] = -95.273467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1787801706, states[0] = -44.726587, states[40]= 0.000062
Saving checkpoint... 
Iteration: 1799428407, states[0] = 17.798204, states[40]= 0.007992
Saving checkpoint... 
Iteration: 1811745022, states[0] = -95.029235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1823152223, states[0] = -91.851819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1834930611, states[0] = -95.113575, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1846733231, states[0] = -94.986188, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1859093989, states[0] = -18.322924, states[40]= 0.001102
Saving checkpoint... 
Iteration: 1870630787, states[0] = -57.546833, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1882401732, states[0] = -95.088535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1894187033, states[0] = -94.892877, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1903359329, states[0] = -95.071804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1914951119, states[0] = -95.095595, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1926762428, states[0] = -95.005781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1938595706, states[0] = -19.397033, states[40]= 0.001006
Saving checkpoint... 
Iteration: 1950666540, states[0] = -94.771581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1962795538, states[0] = -95.033912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1972120907, states[0] = -45.432992, states[40]= 0.000053
Saving checkpoint... 
Iteration: 1984096903, states[0] = -20.552361, states[40]= 0.000919
Saving checkpoint... 
Iteration: 1996501922, states[0] = 47.685339, states[40]= 0.067682
Saving checkpoint... 
Iteration: 2008157772, states[0] = -93.567783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2020253730, states[0] = -94.994792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2032295570, states[0] = -95.033423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2044163898, states[0] = -94.660012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2055672949, states[0] = -94.849913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2067152504, states[0] = -89.336486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2078867027, states[0] = -95.071559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2090909259, states[0] = -95.084553, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.975870
 - CaMKt in component CaMK (millimolar): 0.006484
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.518504
 - nass in component intracellular_ions (millimolar): 6.518563
 - ki in component intracellular_ions (millimolar): 145.465741
 - kss in component intracellular_ions (millimolar): 145.465721
 - cansr in component intracellular_ions (millimolar): 1.287159
 - cajsr in component intracellular_ions (millimolar): 1.250256
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003592
 - hf in component INa (dimensionless): 0.881279
 - hs in component INa (dimensionless): 0.881275
 - j in component INa (dimensionless): 0.881248
 - hsp in component INa (dimensionless): 0.728246
 - jp in component INa (dimensionless): 0.881230
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.713558
 - hLp in component INaL (dimensionless): 0.459416
 - a in component Ito (dimensionless): 0.000620
 - iF in component Ito (dimensionless): 0.999871
 - iS in component Ito (dimensionless): 0.628428
 - ap in component Ito (dimensionless): 0.000316
 - iFp in component Ito (dimensionless): 0.999871
 - iSp in component Ito (dimensionless): 0.704430
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.937399
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999895
 - jca in component ICaL (dimensionless): 0.999980
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001519
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.334083
 - xs1 in component IKs (dimensionless): 0.233748
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997318
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
02:59:21 (2812): called boinc_finish(0)

</stderr_txt>
]]>


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