𝕏

Task 55388521

Name HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_989_0
Workunit 26301313
Created 30 Jun 2024, 3:49:01 UTC
Sent 30 Jun 2024, 5:28:29 UTC
Report deadline 3 Jul 2024, 15:04:29 UTC
Received 3 Jul 2024, 6:10:51 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 213681
Run time 2 hours 45 min 13 sec
CPU time 2 hours 45 min 13 sec
Validate state Valid
Credit 59.71
Device peak FLOPS 3.69 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.16 MB
Peak swap size 6.21 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>8.0.3</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_989.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_989_0_r1763174282_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_989_0_r1763174282_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 102.566938
     * GNaL_b in INaL: 0.006504
     * Gto_b in Ito: 0.074805
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.030940
     * GKs_b in IKs: 0.001870
     * GK1_b in IK1: 0.156901
     * Gncx_b in INaCa_i: 0.000955
     * Pnak_b in INaK: 67.051710
     * GKb_b in IKb: 0.003897
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.026328
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11614510, states[0] = -34.860060, states[40]= 0.000258
Saving checkpoint... 
Iteration: 24393377, states[0] = -95.065947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 36466967, states[0] = -95.067172, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48805825, states[0] = -94.994114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 61022292, states[0] = 21.538798, states[40]= 0.008531
Saving checkpoint... 
Iteration: 73291982, states[0] = -94.970769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 85352981, states[0] = -95.007554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 97808372, states[0] = -94.978225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 110251666, states[0] = -94.919639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 123055431, states[0] = 10.091731, states[40]= 0.005050
Saving checkpoint... 
Iteration: 134338817, states[0] = -94.994168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 147086398, states[0] = -5.953863, states[40]= 0.003226
Saving checkpoint... 
Iteration: 160054110, states[0] = 10.656979, states[40]= 0.005069
Saving checkpoint... 
Iteration: 171808627, states[0] = -94.973432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 183946777, states[0] = -95.030115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 196387595, states[0] = -95.014087, states[40]= 0.000000
Saving checkpoint... 
Iteration: 208922166, states[0] = -95.024288, states[40]= 0.000000
Saving checkpoint... 
Iteration: 220665561, states[0] = -91.185165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 232550800, states[0] = 11.985738, states[40]= 0.005123
Saving checkpoint... 
Iteration: 244887676, states[0] = -95.013835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 257031729, states[0] = 18.962961, states[40]= 0.006132
Saving checkpoint... 
Iteration: 269147801, states[0] = -65.485409, states[40]= 0.000002
Saving checkpoint... 
Iteration: 281108531, states[0] = -25.310949, states[40]= 0.000725
Saving checkpoint... 
Iteration: 293040435, states[0] = 15.934921, states[40]= 0.005434
Saving checkpoint... 
Iteration: 304901622, states[0] = -95.018286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 317365402, states[0] = -95.005087, states[40]= 0.000000
Saving checkpoint... 
Iteration: 329362261, states[0] = -95.003707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 341471214, states[0] = -95.033952, states[40]= 0.000000
Saving checkpoint... 
Iteration: 353906791, states[0] = -95.019790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 366252756, states[0] = -94.916938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 378194479, states[0] = -94.816026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 390442212, states[0] = -95.028574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 402993994, states[0] = -95.037202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 415806027, states[0] = -94.970647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 427794059, states[0] = -94.960946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 439974188, states[0] = -95.034359, states[40]= 0.000000
Saving checkpoint... 
Iteration: 451383445, states[0] = -95.012123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 463550920, states[0] = 11.940643, states[40]= 0.005121
Saving checkpoint... 
Iteration: 476458116, states[0] = -95.031630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 489198039, states[0] = -94.823778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 500721340, states[0] = -94.868851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 513359098, states[0] = -95.002169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 525734289, states[0] = -94.890384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 537726547, states[0] = -94.877801, states[40]= 0.000000
Saving checkpoint... 
Iteration: 549508407, states[0] = 25.463572, states[40]= 0.075296
Saving checkpoint... 
Iteration: 561470176, states[0] = -95.033648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 573471601, states[0] = -95.033870, states[40]= 0.000000
Saving checkpoint... 
Iteration: 585933439, states[0] = -95.026535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 598555939, states[0] = 9.934581, states[40]= 0.005041
Saving checkpoint... 
Iteration: 610619000, states[0] = -34.990425, states[40]= 0.000274
Saving checkpoint... 
Iteration: 623112836, states[0] = -29.263348, states[40]= 0.000530
Saving checkpoint... 
Iteration: 634333143, states[0] = -94.988667, states[40]= 0.000000
Saving checkpoint... 
Iteration: 646997685, states[0] = -95.037525, states[40]= 0.000000
Saving checkpoint... 
Iteration: 658480348, states[0] = -95.035162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 670198074, states[0] = -94.823743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 682188605, states[0] = -94.800237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 694660227, states[0] = -84.080301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 706751427, states[0] = -94.914985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 719063136, states[0] = 6.906151, states[40]= 0.004914
Saving checkpoint... 
Iteration: 731031454, states[0] = 19.052863, states[40]= 0.006167
Saving checkpoint... 
Iteration: 743119969, states[0] = -35.903014, states[40]= 0.000242
Saving checkpoint... 
Iteration: 755480836, states[0] = -95.035176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 767427614, states[0] = -95.025063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 779588016, states[0] = -7.118411, states[40]= 0.002971
Saving checkpoint... 
Iteration: 791964978, states[0] = -95.032647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 802594799, states[0] = -12.786685, states[40]= 0.001821
Saving checkpoint... 
Iteration: 813551105, states[0] = 11.867947, states[40]= 0.005118
Saving checkpoint... 
Iteration: 823113375, states[0] = -29.760271, states[40]= 0.000505
Saving checkpoint... 
Iteration: 835028425, states[0] = 20.000123, states[40]= 0.006634
Saving checkpoint... 
Iteration: 846817290, states[0] = -94.978518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 859754360, states[0] = -94.918715, states[40]= 0.000000
Saving checkpoint... 
Iteration: 871849654, states[0] = -94.997449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 884042097, states[0] = 15.321414, states[40]= 0.005359
Saving checkpoint... 
Iteration: 896455801, states[0] = -95.030954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 908726245, states[0] = -94.877068, states[40]= 0.000000
Saving checkpoint... 
Iteration: 921444676, states[0] = -95.028768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 933982472, states[0] = -95.035308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 946287125, states[0] = -94.954463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 958701134, states[0] = -94.829968, states[40]= 0.000000
Saving checkpoint... 
Iteration: 971018702, states[0] = 22.537483, states[40]= 0.011498
Saving checkpoint... 
Iteration: 983664512, states[0] = -90.133648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 996172916, states[0] = -94.316741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1007690719, states[0] = -94.806356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1019892090, states[0] = -95.014793, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1032348193, states[0] = -94.996619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1044338409, states[0] = -94.991423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1056068739, states[0] = 4.364002, states[40]= 0.004758
Saving checkpoint... 
Iteration: 1068066264, states[0] = 5.511802, states[40]= 0.004836
Saving checkpoint... 
Iteration: 1079413804, states[0] = -95.021333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1089874594, states[0] = -95.008395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1101689872, states[0] = -94.803909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1114509401, states[0] = 24.902504, states[40]= 0.060058
Saving checkpoint... 
Iteration: 1125546880, states[0] = 13.510546, states[40]= 0.005205
Saving checkpoint... 
Iteration: 1136615746, states[0] = -31.953559, states[40]= 0.000399
Saving checkpoint... 
Iteration: 1148636417, states[0] = -52.543789, states[40]= 0.000019
Saving checkpoint... 
Iteration: 1160251120, states[0] = -94.914305, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1172295051, states[0] = -94.961347, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1184125042, states[0] = -40.780315, states[40]= 0.000121
Saving checkpoint... 
Iteration: 1196270882, states[0] = -94.938048, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1207703590, states[0] = -94.834825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1220099054, states[0] = -16.627963, states[40]= 0.001281
Saving checkpoint... 
Iteration: 1231654566, states[0] = -74.774150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1244071602, states[0] = 2.976678, states[40]= 0.004643
Saving checkpoint... 
Iteration: 1256472002, states[0] = -95.033526, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1268859620, states[0] = -95.001954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1281407355, states[0] = -95.019395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1293495916, states[0] = -95.036916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1306085074, states[0] = -4.941045, states[40]= 0.003439
Saving checkpoint... 
Iteration: 1318167200, states[0] = -92.417461, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1330477941, states[0] = -95.034402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1342801798, states[0] = -94.966797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1354744743, states[0] = -94.905452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1366420365, states[0] = -95.022901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1378844339, states[0] = -94.994426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1390661372, states[0] = -85.919869, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1402224841, states[0] = -94.874386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1414976712, states[0] = -95.034165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1427457285, states[0] = -95.030910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1439721272, states[0] = -94.868166, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1451218401, states[0] = -94.863033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1463726275, states[0] = -94.876785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1475363143, states[0] = -95.003403, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1487045095, states[0] = 14.193124, states[40]= 0.005253
Saving checkpoint... 
Iteration: 1498735876, states[0] = -94.892265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1511108973, states[0] = 26.215684, states[40]= 0.063960
Saving checkpoint... 
Iteration: 1523514107, states[0] = -49.050125, states[40]= 0.000035
Saving checkpoint... 
Iteration: 1535801325, states[0] = -35.490720, states[40]= 0.000255
Saving checkpoint... 
Iteration: 1548364991, states[0] = -0.442922, states[40]= 0.004778
Saving checkpoint... 
Iteration: 1560854480, states[0] = -95.275992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1573478383, states[0] = -95.302455, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1585216938, states[0] = 22.789909, states[40]= 0.015731
Saving checkpoint... 
Iteration: 1597772501, states[0] = -95.301587, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1610383226, states[0] = -95.311741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1622543321, states[0] = -92.525898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1633444492, states[0] = -95.275101, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1645532441, states[0] = 16.786458, states[40]= 0.007008
Saving checkpoint... 
Iteration: 1658128711, states[0] = 18.395907, states[40]= 0.007615
Saving checkpoint... 
Iteration: 1670582961, states[0] = -95.170681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1683511053, states[0] = -95.227545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1696092940, states[0] = -95.192955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1708595433, states[0] = -30.591861, states[40]= 0.000452
Saving checkpoint... 
Iteration: 1720474069, states[0] = -95.306438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1732317351, states[0] = -55.374352, states[40]= 0.000013
Saving checkpoint... 
Iteration: 1744776029, states[0] = -95.308146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1756978814, states[0] = -95.161103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1768930044, states[0] = -72.545805, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1781105125, states[0] = 31.017983, states[40]= 0.123521
Saving checkpoint... 
Iteration: 1792120527, states[0] = -95.243287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1804732202, states[0] = -94.937790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1817077511, states[0] = -1.560972, states[40]= 0.004141
Saving checkpoint... 
Iteration: 1829584654, states[0] = -5.885213, states[40]= 0.003272
Saving checkpoint... 
Iteration: 1841870586, states[0] = -95.028129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1854361101, states[0] = -95.017498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1866765489, states[0] = -94.942403, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1879464787, states[0] = -95.039322, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1892826978, states[0] = -94.989226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1905913653, states[0] = -95.024222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1919198352, states[0] = -94.825943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1932746712, states[0] = -94.909457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1946031070, states[0] = 19.163403, states[40]= 0.006216
Saving checkpoint... 
Iteration: 1958975907, states[0] = -95.034430, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1971350391, states[0] = -94.997644, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1984727704, states[0] = -94.879189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1998365989, states[0] = -95.004518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2012722140, states[0] = -94.869461, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2027147869, states[0] = -65.573922, states[40]= 0.000002
Saving checkpoint... 
Iteration: 2041476503, states[0] = -95.033778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2055827136, states[0] = -94.984194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2070225532, states[0] = -94.875140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2084595931, states[0] = -13.796834, states[40]= 0.001656
Saving checkpoint... 
Iteration: 2098993066, states[0] = -95.036028, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.912779
 - CaMKt in component CaMK (millimolar): 0.006977
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.628167
 - nass in component intracellular_ions (millimolar): 6.628227
 - ki in component intracellular_ions (millimolar): 145.349368
 - kss in component intracellular_ions (millimolar): 145.349348
 - cansr in component intracellular_ions (millimolar): 1.314249
 - cajsr in component intracellular_ions (millimolar): 1.276168
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003615
 - hf in component INa (dimensionless): 0.880190
 - hs in component INa (dimensionless): 0.880185
 - j in component INa (dimensionless): 0.880155
 - hsp in component INa (dimensionless): 0.726186
 - jp in component INa (dimensionless): 0.880135
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.709348
 - hLp in component INaL (dimensionless): 0.449774
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.617992
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.691954
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.931896
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999874
 - jca in component ICaL (dimensionless): 0.999976
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001620
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.341746
 - xs1 in component IKs (dimensionless): 0.246627
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997334
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
23:10:16 (20000): called boinc_finish(0)

</stderr_txt>
]]>


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