𝕏

Task 55388258

Name HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_476_1
Workunit 26301181
Created 30 Jun 2024, 3:48:51 UTC
Sent 30 Jun 2024, 5:35:49 UTC
Report deadline 3 Jul 2024, 15:11:49 UTC
Received 3 Jul 2024, 17:34:10 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 213933
Run time 2 hours 44 min 34 sec
CPU time 2 hours 17 min 47 sec
Validate state Valid
Credit 65.15
Device peak FLOPS 3.66 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.32 MB
Peak swap size 5.40 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_476.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_476_1_r672803731_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_476_1_r672803731_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 101.008075
     * GNaL_b in INaL: 0.005120
     * Gto_b in Ito: 0.095600
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032702
     * GKs_b in IKs: 0.001805
     * GK1_b in IK1: 0.174463
     * Gncx_b in INaCa_i: 0.000962
     * Pnak_b in INaK: 74.101249
     * GKb_b in IKb: 0.003905
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.023913
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12169116, states[0] = -94.991865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 26178609, states[0] = -94.971675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 40513789, states[0] = 20.712770, states[40]= 0.021825
Saving checkpoint... 
Iteration: 54965793, states[0] = -95.174460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 69318533, states[0] = -95.116191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 83697287, states[0] = -94.961113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 98138077, states[0] = -60.286527, states[40]= 0.000005
Saving checkpoint... 
Iteration: 112547245, states[0] = 12.005460, states[40]= 0.004814
Saving checkpoint... 
Iteration: 127028695, states[0] = 18.197113, states[40]= 0.005797
Saving checkpoint... 
Iteration: 141520330, states[0] = 20.092238, states[40]= 0.008620
Saving checkpoint... 
Iteration: 155957680, states[0] = -95.151426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 170403181, states[0] = -95.138871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 184909953, states[0] = -95.140481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 198744035, states[0] = -95.031516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 212914532, states[0] = -95.141402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 226624325, states[0] = -44.524552, states[40]= 0.000066
Saving checkpoint... 
Iteration: 240462232, states[0] = -95.151149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 254353394, states[0] = -95.120185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 267626058, states[0] = -46.348051, states[40]= 0.000050
Saving checkpoint... 
Iteration: 281926016, states[0] = -95.143969, states[40]= 0.000000
Saving checkpoint... 
Iteration: 296232860, states[0] = -95.015208, states[40]= 0.000000
Saving checkpoint... 
Iteration: 310549808, states[0] = 11.113542, states[40]= 0.004788
Saving checkpoint... 
Iteration: 324430554, states[0] = -95.144942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 338715077, states[0] = -94.985813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 351636749, states[0] = -58.185361, states[40]= 0.000007
Saving checkpoint... 
Iteration: 365926263, states[0] = -95.143940, states[40]= 0.000000
Saving checkpoint... 
Iteration: 380327812, states[0] = -95.106921, states[40]= 0.000000
Saving checkpoint... 
Iteration: 394650929, states[0] = -78.181185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 408506288, states[0] = 23.868774, states[40]= 0.128116
Saving checkpoint... 
Iteration: 422828114, states[0] = -95.107063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 437191493, states[0] = -94.938823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 449160547, states[0] = -92.611976, states[40]= 0.000000
Saving checkpoint... 
Iteration: 463423100, states[0] = -95.143128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 477738171, states[0] = -95.022861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 491653100, states[0] = -82.203517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 505958436, states[0] = -95.150229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 519909434, states[0] = -95.139644, states[40]= 0.000000
Saving checkpoint... 
Iteration: 534323831, states[0] = -95.104457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 548610802, states[0] = -31.021144, states[40]= 0.000417
Saving checkpoint... 
Iteration: 562903614, states[0] = -95.138009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 577238180, states[0] = -95.022800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 591119353, states[0] = -39.412883, states[40]= 0.000141
Saving checkpoint... 
Iteration: 605250315, states[0] = -95.039099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 619408365, states[0] = -95.139281, states[40]= 0.000000
Saving checkpoint... 
Iteration: 633691549, states[0] = -94.938796, states[40]= 0.000000
Saving checkpoint... 
Iteration: 648047530, states[0] = 11.969742, states[40]= 0.004811
Saving checkpoint... 
Iteration: 662318532, states[0] = -95.101090, states[40]= 0.000000
Saving checkpoint... 
Iteration: 676677759, states[0] = -94.900799, states[40]= 0.000000
Saving checkpoint... 
Iteration: 691054739, states[0] = 9.199800, states[40]= 0.004752
Saving checkpoint... 
Iteration: 705383110, states[0] = -95.131515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 719698291, states[0] = -94.953051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 733978513, states[0] = -95.153189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 748301844, states[0] = -95.089537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 762625353, states[0] = -45.596940, states[40]= 0.000056
Saving checkpoint... 
Iteration: 776981188, states[0] = -95.153531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 791078454, states[0] = -2.337496, states[40]= 0.003855
Saving checkpoint... 
Iteration: 805313480, states[0] = -95.097703, states[40]= 0.000000
Saving checkpoint... 
Iteration: 819611761, states[0] = -31.948328, states[40]= 0.000376
Saving checkpoint... 
Iteration: 833786112, states[0] = -95.076744, states[40]= 0.000000
Saving checkpoint... 
Iteration: 848067254, states[0] = 3.791590, states[40]= 0.004553
Saving checkpoint... 
Iteration: 862329790, states[0] = -95.107693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 876592224, states[0] = -13.278572, states[40]= 0.001716
Saving checkpoint... 
Iteration: 890897160, states[0] = -95.135882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 905201409, states[0] = -94.959288, states[40]= 0.000000
Saving checkpoint... 
Iteration: 919549400, states[0] = 11.268412, states[40]= 0.004791
Saving checkpoint... 
Iteration: 933883145, states[0] = -95.131356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 948198482, states[0] = -94.953274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 961750575, states[0] = -95.039159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 975453723, states[0] = -95.149056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 989452746, states[0] = -95.148870, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1003465550, states[0] = -95.151034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1017806819, states[0] = -95.092961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1031405248, states[0] = -95.138117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1043475653, states[0] = -95.152547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1057808776, states[0] = -95.094309, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1072091829, states[0] = -12.913186, states[40]= 0.001776
Saving checkpoint... 
Iteration: 1086360618, states[0] = -95.122665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1100689040, states[0] = -94.932897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1114943236, states[0] = -95.146987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1129365923, states[0] = -95.124819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1143731373, states[0] = -95.012293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1158046796, states[0] = 12.242193, states[40]= 0.004820
Saving checkpoint... 
Iteration: 1171967656, states[0] = -95.151241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1186365896, states[0] = -95.124766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1200731298, states[0] = -95.012135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1214847926, states[0] = -95.116871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1226766899, states[0] = -95.057882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1240638431, states[0] = -60.161230, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1254867261, states[0] = -95.125260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1269220640, states[0] = -94.994841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1283593463, states[0] = -14.434368, states[40]= 0.001537
Saving checkpoint... 
Iteration: 1298002569, states[0] = 38.533275, states[40]= 0.133710
Saving checkpoint... 
Iteration: 1312369082, states[0] = -95.125933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1326577044, states[0] = -1.456619, states[40]= 0.003994
Saving checkpoint... 
Iteration: 1340825517, states[0] = -95.104859, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1355146642, states[0] = -71.036831, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1368645095, states[0] = -68.759471, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1383028129, states[0] = 18.380878, states[40]= 0.005884
Saving checkpoint... 
Iteration: 1397432692, states[0] = -95.144601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1411230150, states[0] = -95.010206, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1425479893, states[0] = -95.152867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1439786479, states[0] = -95.076610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1454173254, states[0] = -94.863466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1468456362, states[0] = -95.149153, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1482817415, states[0] = -95.099765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1495596116, states[0] = -16.946392, states[40]= 0.001221
Saving checkpoint... 
Iteration: 1508827483, states[0] = -71.817429, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1521505512, states[0] = -95.278488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1534858227, states[0] = 2.580627, states[40]= 0.005042
Saving checkpoint... 
Iteration: 1542731715, states[0] = -83.790876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1556500512, states[0] = -39.910541, states[40]= 0.000133
Saving checkpoint... 
Iteration: 1569602799, states[0] = 37.875804, states[40]= 0.116974
Saving checkpoint... 
Iteration: 1584095345, states[0] = -34.491005, states[40]= 0.000274
Saving checkpoint... 
Iteration: 1596835546, states[0] = -95.354374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1610804468, states[0] = -45.160560, states[40]= 0.000062
Saving checkpoint... 
Iteration: 1626005425, states[0] = 26.648184, states[40]= 0.135926
Saving checkpoint... 
Iteration: 1641362228, states[0] = -0.693235, states[40]= 0.004634
Saving checkpoint... 
Iteration: 1654243574, states[0] = 10.185112, states[40]= 0.005650
Saving checkpoint... 
Iteration: 1667911861, states[0] = -95.323430, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1678811296, states[0] = 21.933635, states[40]= 0.039605
Saving checkpoint... 
Iteration: 1691878520, states[0] = -95.258260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1705268309, states[0] = -5.562852, states[40]= 0.003671
Saving checkpoint... 
Iteration: 1718229283, states[0] = -81.230796, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1729875192, states[0] = -12.374683, states[40]= 0.002121
Saving checkpoint... 
Iteration: 1741577154, states[0] = -14.504497, states[40]= 0.001729
Saving checkpoint... 
Iteration: 1755732155, states[0] = -86.779948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1768537874, states[0] = 12.932195, states[40]= 0.005931
Saving checkpoint... 
Iteration: 1782072331, states[0] = -9.392269, states[40]= 0.002770
Saving checkpoint... 
Iteration: 1798151272, states[0] = -95.375057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1813710404, states[0] = -95.016666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1826686846, states[0] = -94.956868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1839402898, states[0] = -95.157236, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1851741788, states[0] = -95.041249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1864458701, states[0] = -95.158774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1877568144, states[0] = 3.188899, states[40]= 0.004516
Saving checkpoint... 
Iteration: 1890920554, states[0] = -95.145699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1903829591, states[0] = -95.109674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1916316333, states[0] = -95.100701, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1930574991, states[0] = -0.284194, states[40]= 0.004160
Saving checkpoint... 
Iteration: 1943658966, states[0] = -91.359201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1956541259, states[0] = 14.234147, states[40]= 0.004929
Saving checkpoint... 
Iteration: 1968555542, states[0] = 8.870771, states[40]= 0.004746
Saving checkpoint... 
Iteration: 1983369860, states[0] = -95.125936, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1996827310, states[0] = -95.105532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2010442214, states[0] = -95.146168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2024025560, states[0] = 19.026779, states[40]= 0.006373
Saving checkpoint... 
Iteration: 2036559289, states[0] = 7.342062, states[40]= 0.004711
Saving checkpoint... 
Iteration: 2049230774, states[0] = -95.010661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2062269095, states[0] = -95.059523, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2074869789, states[0] = -95.125587, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2088379902, states[0] = -95.129310, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -95.030745
 - CaMKt in component CaMK (millimolar): 0.007225
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.470609
 - nass in component intracellular_ions (millimolar): 6.470670
 - ki in component intracellular_ions (millimolar): 145.502457
 - kss in component intracellular_ions (millimolar): 145.502436
 - cansr in component intracellular_ions (millimolar): 1.327132
 - cajsr in component intracellular_ions (millimolar): 1.288920
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003572
 - hf in component INa (dimensionless): 0.882219
 - hs in component INa (dimensionless): 0.882215
 - j in component INa (dimensionless): 0.882186
 - hsp in component INa (dimensionless): 0.730025
 - jp in component INa (dimensionless): 0.882168
 - mL in component INaL (dimensionless): 0.000048
 - hL in component INaL (dimensionless): 0.713832
 - hLp in component INaL (dimensionless): 0.457491
 - a in component Ito (dimensionless): 0.000618
 - iF in component Ito (dimensionless): 0.999873
 - iS in component Ito (dimensionless): 0.624146
 - ap in component Ito (dimensionless): 0.000315
 - iFp in component Ito (dimensionless): 0.999873
 - iSp in component Ito (dimensionless): 0.700124
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.938342
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999895
 - jca in component ICaL (dimensionless): 0.999979
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001654
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.316443
 - xs1 in component IKs (dimensionless): 0.237747
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997303
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
19:33:41 (14940): called boinc_finish(0)

</stderr_txt>
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