𝕏

Task 55388147

Name HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_871_1
Workunit 26301126
Created 30 Jun 2024, 3:48:46 UTC
Sent 30 Jun 2024, 5:27:07 UTC
Report deadline 3 Jul 2024, 15:03:07 UTC
Received 30 Jun 2024, 10:00:52 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 230332
Run time 2 hours 17 min 42 sec
CPU time 2 hours 12 min 4 sec
Validate state Valid
Credit 61.69
Device peak FLOPS 3.58 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 5.83 MB
Peak swap size 1.52 MB
Peak disk usage 0.27 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_871.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_871_1_r1727299792_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_871_1_r1727299792_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 114.114144
     * GNaL_b in INaL: 0.005309
     * Gto_b in Ito: 0.090857
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.032496
     * GKs_b in IKs: 0.002107
     * GK1_b in IK1: 0.152036
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 73.121423
     * GKb_b in IKb: 0.003932
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.019118
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 17125163, states[0] = -52.510282, states[40]= 0.000017
Saving checkpoint... 
Iteration: 34364853, states[0] = -94.965113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 51600300, states[0] = -24.182923, states[40]= 0.000730
Saving checkpoint... 
Iteration: 68842100, states[0] = -94.920061, states[40]= 0.000000
Saving checkpoint... 
Iteration: 85992481, states[0] = -94.959017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 103174634, states[0] = -94.612965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 120469301, states[0] = -94.948935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 137716778, states[0] = -94.762464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 154947586, states[0] = -94.942473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 172163724, states[0] = -93.212094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 189378147, states[0] = -94.920931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 206634561, states[0] = -57.405852, states[40]= 0.000008
Saving checkpoint... 
Iteration: 223862028, states[0] = -94.913554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 241064738, states[0] = 4.311917, states[40]= 0.004678
Saving checkpoint... 
Iteration: 258205130, states[0] = -94.735953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 275453280, states[0] = -94.942346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 292703678, states[0] = -94.732699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 309964699, states[0] = -94.944476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 327204225, states[0] = -94.733869, states[40]= 0.000000
Saving checkpoint... 
Iteration: 344344633, states[0] = -94.904370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 361592851, states[0] = -15.584268, states[40]= 0.001399
Saving checkpoint... 
Iteration: 378890792, states[0] = -94.925192, states[40]= 0.000000
Saving checkpoint... 
Iteration: 396115961, states[0] = -37.968471, states[40]= 0.000171
Saving checkpoint... 
Iteration: 413370435, states[0] = -94.917084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 430612312, states[0] = -34.389203, states[40]= 0.000276
Saving checkpoint... 
Iteration: 447801958, states[0] = -94.874744, states[40]= 0.000000
Saving checkpoint... 
Iteration: 465043915, states[0] = 13.025934, states[40]= 0.005056
Saving checkpoint... 
Iteration: 482309142, states[0] = -94.880602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 499551525, states[0] = 10.057435, states[40]= 0.004915
Saving checkpoint... 
Iteration: 516793581, states[0] = -94.867281, states[40]= 0.000000
Saving checkpoint... 
Iteration: 533950266, states[0] = -94.941521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 551082925, states[0] = -6.715881, states[40]= 0.003055
Saving checkpoint... 
Iteration: 568300472, states[0] = -94.873390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 585521676, states[0] = 20.030854, states[40]= 0.008324
Saving checkpoint... 
Iteration: 602797667, states[0] = -94.870916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 619954614, states[0] = -94.942342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 637152516, states[0] = -80.611786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 654414234, states[0] = -94.932584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 671567124, states[0] = 3.148988, states[40]= 0.004594
Saving checkpoint... 
Iteration: 688763711, states[0] = -94.834964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 706043271, states[0] = 13.268825, states[40]= 0.005075
Saving checkpoint... 
Iteration: 723179516, states[0] = -94.660300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 740433572, states[0] = -94.937645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 757640997, states[0] = -64.634295, states[40]= 0.000002
Saving checkpoint... 
Iteration: 774875454, states[0] = -94.918974, states[40]= 0.000000
Saving checkpoint... 
Iteration: 792085153, states[0] = -8.545050, states[40]= 0.002661
Saving checkpoint... 
Iteration: 809290504, states[0] = -94.864195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 826554083, states[0] = 9.014688, states[40]= 0.004881
Saving checkpoint... 
Iteration: 843843960, states[0] = -94.903644, states[40]= 0.000000
Saving checkpoint... 
Iteration: 861041811, states[0] = 13.814566, states[40]= 0.005121
Saving checkpoint... 
Iteration: 878195409, states[0] = -94.713407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 895464814, states[0] = -94.944081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 912678913, states[0] = -94.655726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 929939677, states[0] = -94.938948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 947108560, states[0] = -30.747623, states[40]= 0.000424
Saving checkpoint... 
Iteration: 964377100, states[0] = -94.919523, states[40]= 0.000000
Saving checkpoint... 
Iteration: 981627260, states[0] = -49.555160, states[40]= 0.000029
Saving checkpoint... 
Iteration: 998926622, states[0] = -94.935732, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1016078602, states[0] = -3.516934, states[40]= 0.003706
Saving checkpoint... 
Iteration: 1033214683, states[0] = -94.755476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1050453769, states[0] = -94.941877, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1067624156, states[0] = -46.290386, states[40]= 0.000049
Saving checkpoint... 
Iteration: 1084866052, states[0] = -94.914667, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1102127666, states[0] = -49.985380, states[40]= 0.000027
Saving checkpoint... 
Iteration: 1119527316, states[0] = 18.626601, states[40]= 0.006401
Saving checkpoint... 
Iteration: 1136994123, states[0] = -94.948524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1154421601, states[0] = -94.934300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1171897927, states[0] = -94.927131, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1189290086, states[0] = -94.863533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1206742942, states[0] = -94.805669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1224157865, states[0] = -88.614085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1241580245, states[0] = -4.678153, states[40]= 0.003481
Saving checkpoint... 
Iteration: 1258987240, states[0] = -94.947471, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1276374049, states[0] = -94.918039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1293835247, states[0] = -94.898225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1311228016, states[0] = -94.780720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1327980848, states[0] = -94.946464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1344220383, states[0] = -94.766516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1360436676, states[0] = -94.937957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1376731875, states[0] = -94.787462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1393160922, states[0] = -91.631828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1409587742, states[0] = -10.809728, states[40]= 0.002191
Saving checkpoint... 
Iteration: 1425841383, states[0] = -94.901776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1442244511, states[0] = -94.807912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1458880123, states[0] = -94.920404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1474660319, states[0] = -91.154987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1490934250, states[0] = -94.937291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1507254499, states[0] = 5.017251, states[40]= 0.005278
Saving checkpoint... 
Iteration: 1523780243, states[0] = -17.426244, states[40]= 0.001311
Saving checkpoint... 
Iteration: 1539696082, states[0] = -35.770905, states[40]= 0.000231
Saving checkpoint... 
Iteration: 1555573158, states[0] = -10.810810, states[40]= 0.002471
Saving checkpoint... 
Iteration: 1571086720, states[0] = -95.238611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1587074482, states[0] = -12.596433, states[40]= 0.002097
Saving checkpoint... 
Iteration: 1602284154, states[0] = -95.242079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1616706867, states[0] = 25.476946, states[40]= 0.105641
Saving checkpoint... 
Iteration: 1631798883, states[0] = -40.061282, states[40]= 0.000129
Saving checkpoint... 
Iteration: 1646038256, states[0] = -95.195098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1660278276, states[0] = -16.990406, states[40]= 0.001375
Saving checkpoint... 
Iteration: 1674927764, states[0] = 17.280960, states[40]= 0.007387
Saving checkpoint... 
Iteration: 1689103458, states[0] = -45.414668, states[40]= 0.000059
Saving checkpoint... 
Iteration: 1704124652, states[0] = -72.463819, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1721229920, states[0] = -81.155348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1738733776, states[0] = -95.189426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1756011285, states[0] = -54.819840, states[40]= 0.000013
Saving checkpoint... 
Iteration: 1772786581, states[0] = -26.331493, states[40]= 0.000631
Saving checkpoint... 
Iteration: 1790011435, states[0] = -95.152996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1807670830, states[0] = -94.645472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1825338277, states[0] = -94.938471, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1842893733, states[0] = -94.948260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1860391781, states[0] = -94.938070, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1877630112, states[0] = -53.091048, states[40]= 0.000016
Saving checkpoint... 
Iteration: 1895065158, states[0] = 4.016590, states[40]= 0.004661
Saving checkpoint... 
Iteration: 1912756379, states[0] = -94.827388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1929981885, states[0] = -94.947818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1947744838, states[0] = -94.808999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1965082238, states[0] = -6.196784, states[40]= 0.003166
Saving checkpoint... 
Iteration: 1982530139, states[0] = 17.802150, states[40]= 0.005951
Saving checkpoint... 
Iteration: 2000275781, states[0] = -94.848401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2017817574, states[0] = -94.885992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2035409408, states[0] = -94.930215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2052981391, states[0] = -94.946030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2070573407, states[0] = -0.232079, states[40]= 0.004236
Saving checkpoint... 
Iteration: 2088076744, states[0] = -2.278768, states[40]= 0.003927
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.824465
 - CaMKt in component CaMK (millimolar): 0.007080
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.534158
 - nass in component intracellular_ions (millimolar): 6.534219
 - ki in component intracellular_ions (millimolar): 145.440776
 - kss in component intracellular_ions (millimolar): 145.440756
 - cansr in component intracellular_ions (millimolar): 1.321872
 - cajsr in component intracellular_ions (millimolar): 1.284102
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003647
 - hf in component INa (dimensionless): 0.878652
 - hs in component INa (dimensionless): 0.878646
 - j in component INa (dimensionless): 0.878614
 - hsp in component INa (dimensionless): 0.723289
 - jp in component INa (dimensionless): 0.878592
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.708327
 - hLp in component INaL (dimensionless): 0.451054
 - a in component Ito (dimensionless): 0.000627
 - iF in component Ito (dimensionless): 0.999868
 - iS in component Ito (dimensionless): 0.623958
 - ap in component Ito (dimensionless): 0.000319
 - iFp in component Ito (dimensionless): 0.999868
 - iSp in component Ito (dimensionless): 0.699483
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.939155
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999897
 - jca in component ICaL (dimensionless): 0.999980
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001637
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.328622
 - xs1 in component IKs (dimensionless): 0.234152
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997357
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
11:00:40 (8908): called boinc_finish(0)

</stderr_txt>
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