𝕏

Task 55388103

Name HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_769_1
Workunit 26301104
Created 30 Jun 2024, 3:48:46 UTC
Sent 30 Jun 2024, 5:27:07 UTC
Report deadline 3 Jul 2024, 15:03:07 UTC
Received 30 Jun 2024, 9:20:58 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 230332
Run time 2 hours 16 min 35 sec
CPU time 2 hours 13 min 36 sec
Validate state Valid
Credit 60.16
Device peak FLOPS 3.58 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 5.83 MB
Peak swap size 1.52 MB
Peak disk usage 0.27 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_769.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_769_1_r493176979_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_769_1_r493176979_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 94.900548
     * GNaL_b in INaL: 0.004453
     * Gto_b in Ito: 0.099587
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032559
     * GKs_b in IKs: 0.001868
     * GK1_b in IK1: 0.161336
     * Gncx_b in INaCa_i: 0.000977
     * Pnak_b in INaK: 67.303405
     * GKb_b in IKb: 0.003691
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.028869
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 16932736, states[0] = -95.057103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 34111132, states[0] = -32.926717, states[40]= 0.000326
Saving checkpoint... 
Iteration: 51334775, states[0] = -94.981234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 68445057, states[0] = -95.013607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 85644913, states[0] = -67.023992, states[40]= 0.000001
Saving checkpoint... 
Iteration: 102816308, states[0] = -94.954925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 119967551, states[0] = -95.009160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 137126159, states[0] = -46.075804, states[40]= 0.000051
Saving checkpoint... 
Iteration: 154288774, states[0] = -94.929574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 171485177, states[0] = -95.009937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 188654589, states[0] = -80.755313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 205750022, states[0] = -94.885012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 222907799, states[0] = -94.993345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 240075886, states[0] = -0.784048, states[40]= 0.004035
Saving checkpoint... 
Iteration: 257224040, states[0] = -94.844067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 274429835, states[0] = -94.999028, states[40]= 0.000000
Saving checkpoint... 
Iteration: 291615303, states[0] = -35.201573, states[40]= 0.000248
Saving checkpoint... 
Iteration: 308873335, states[0] = -94.981287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 326091157, states[0] = -12.242750, states[40]= 0.001869
Saving checkpoint... 
Iteration: 343285230, states[0] = -94.925183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 360496050, states[0] = -95.010705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 377645340, states[0] = -66.990945, states[40]= 0.000001
Saving checkpoint... 
Iteration: 394765509, states[0] = -94.904275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 411880133, states[0] = -94.983851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 429030241, states[0] = 17.480383, states[40]= 0.005391
Saving checkpoint... 
Iteration: 446235819, states[0] = -94.863659, states[40]= 0.000000
Saving checkpoint... 
Iteration: 463293232, states[0] = -94.932423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 480494631, states[0] = -95.010426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 497470517, states[0] = -95.006893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 514645355, states[0] = -67.009526, states[40]= 0.000001
Saving checkpoint... 
Iteration: 531851411, states[0] = -94.971273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 548964378, states[0] = -95.005822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 566144262, states[0] = -65.652805, states[40]= 0.000002
Saving checkpoint... 
Iteration: 583359690, states[0] = -94.975186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 600713594, states[0] = -94.824239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 617755866, states[0] = -94.892250, states[40]= 0.000000
Saving checkpoint... 
Iteration: 634996555, states[0] = -95.010552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 652192748, states[0] = -94.779678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 669364644, states[0] = -94.977339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 686469151, states[0] = -95.006520, states[40]= 0.000000
Saving checkpoint... 
Iteration: 703646490, states[0] = -68.465006, states[40]= 0.000001
Saving checkpoint... 
Iteration: 720865216, states[0] = -94.977549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 738066451, states[0] = 4.103009, states[40]= 0.004496
Saving checkpoint... 
Iteration: 755233044, states[0] = -94.858957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 772478578, states[0] = -95.007943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 789650065, states[0] = -73.440613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 806852904, states[0] = -94.971792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 823981549, states[0] = -95.008346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 841169123, states[0] = -94.284314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 858324552, states[0] = -94.955782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 875540766, states[0] = 14.176080, states[40]= 0.004792
Saving checkpoint... 
Iteration: 892731766, states[0] = -94.856753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 909942456, states[0] = -95.001336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 927128473, states[0] = -48.363858, states[40]= 0.000035
Saving checkpoint... 
Iteration: 944300971, states[0] = -94.938597, states[40]= 0.000000
Saving checkpoint... 
Iteration: 961497529, states[0] = -95.010419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 978691185, states[0] = -94.775682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 995942498, states[0] = -95.001277, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1013206852, states[0] = -94.810334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1030394949, states[0] = -94.988596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1047617657, states[0] = -37.485046, states[40]= 0.000182
Saving checkpoint... 
Iteration: 1064814269, states[0] = -94.948644, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1081913917, states[0] = -94.994281, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1099061746, states[0] = 6.198361, states[40]= 0.004588
Saving checkpoint... 
Iteration: 1116261718, states[0] = -94.899186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1133441033, states[0] = -95.000857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1150499904, states[0] = -95.010567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1167597016, states[0] = -17.728176, states[40]= 0.001128
Saving checkpoint... 
Iteration: 1184734603, states[0] = -94.861136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1201904692, states[0] = -94.991528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1219059840, states[0] = 7.003092, states[40]= 0.004610
Saving checkpoint... 
Iteration: 1236304037, states[0] = -94.940826, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1253448909, states[0] = -95.002393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1270647687, states[0] = -70.058893, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1287883280, states[0] = -94.984334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1305046487, states[0] = 12.157735, states[40]= 0.004693
Saving checkpoint... 
Iteration: 1322135909, states[0] = -56.199601, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1339336478, states[0] = -94.962658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1356541181, states[0] = 14.033358, states[40]= 0.004782
Saving checkpoint... 
Iteration: 1373655427, states[0] = -82.138493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1390830482, states[0] = -94.959075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1407976502, states[0] = -95.007126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1425093934, states[0] = -14.811645, states[40]= 0.001466
Saving checkpoint... 
Iteration: 1442283672, states[0] = -94.922811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1459510799, states[0] = 20.730035, states[40]= 0.042155
Saving checkpoint... 
Iteration: 1476701966, states[0] = -94.799655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1493845238, states[0] = -94.967355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1511017978, states[0] = -95.156346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1528079290, states[0] = -95.094789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1545157284, states[0] = -95.036227, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1562269297, states[0] = -95.089540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1579337201, states[0] = -90.700421, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1596511490, states[0] = -95.191505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1613621362, states[0] = -95.209520, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1630663985, states[0] = -95.083920, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1647759533, states[0] = -95.068568, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1664907209, states[0] = -95.187078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1682043322, states[0] = -95.241989, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1699264619, states[0] = -2.616473, states[40]= 0.004249
Saving checkpoint... 
Iteration: 1716647373, states[0] = 8.073688, states[40]= 0.005386
Saving checkpoint... 
Iteration: 1733928608, states[0] = -95.222462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1751285496, states[0] = -95.142095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1768559201, states[0] = 1.237055, states[40]= 0.004840
Saving checkpoint... 
Iteration: 1785840547, states[0] = -95.238644, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1802986741, states[0] = -95.069812, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1820281246, states[0] = -94.960256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1837581043, states[0] = -4.983251, states[40]= 0.003342
Saving checkpoint... 
Iteration: 1854861597, states[0] = -94.990040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1872090915, states[0] = -12.475848, states[40]= 0.001832
Saving checkpoint... 
Iteration: 1889335045, states[0] = -94.966837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1906622040, states[0] = -42.014599, states[40]= 0.000094
Saving checkpoint... 
Iteration: 1922827428, states[0] = -94.958781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1939434094, states[0] = -94.999890, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1955251055, states[0] = -94.885578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1971371326, states[0] = -94.979582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1987707172, states[0] = -94.810472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2004242335, states[0] = -94.872539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2020575935, states[0] = -0.813302, states[40]= 0.004031
Saving checkpoint... 
Iteration: 2036769075, states[0] = -94.907069, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2052601277, states[0] = -21.790634, states[40]= 0.000840
Saving checkpoint... 
Iteration: 2068969085, states[0] = -95.005375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2085457760, states[0] = -95.003376, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.885644
 - CaMKt in component CaMK (millimolar): 0.007243
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.662199
 - nass in component intracellular_ions (millimolar): 6.662260
 - ki in component intracellular_ions (millimolar): 145.310691
 - kss in component intracellular_ions (millimolar): 145.310671
 - cansr in component intracellular_ions (millimolar): 1.326031
 - cajsr in component intracellular_ions (millimolar): 1.287793
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003624
 - hf in component INa (dimensionless): 0.879719
 - hs in component INa (dimensionless): 0.879714
 - j in component INa (dimensionless): 0.879683
 - hsp in component INa (dimensionless): 0.725298
 - jp in component INa (dimensionless): 0.879663
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.709510
 - hLp in component INaL (dimensionless): 0.451585
 - a in component Ito (dimensionless): 0.000624
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.622078
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.697616
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.939295
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999897
 - jca in component ICaL (dimensionless): 0.999979
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001640
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.310008
 - xs1 in component IKs (dimensionless): 0.237380
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997341
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
10:20:47 (11588): called boinc_finish(0)

</stderr_txt>
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