𝕏

Task 55387983

Name HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_962_1
Workunit 26301044
Created 30 Jun 2024, 3:48:36 UTC
Sent 30 Jun 2024, 5:25:22 UTC
Report deadline 3 Jul 2024, 15:01:22 UTC
Received 3 Jul 2024, 2:40:28 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 213681
Run time 2 hours 49 min 46 sec
CPU time 2 hours 45 min 44 sec
Validate state Valid
Credit 60.38
Device peak FLOPS 3.69 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.16 MB
Peak swap size 6.22 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>8.0.3</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_962.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_962_1_r1746994747_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_962_1_r1746994747_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 105.713596
     * GNaL_b in INaL: 0.005430
     * Gto_b in Ito: 0.081435
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030911
     * GKs_b in IKs: 0.001893
     * GK1_b in IK1: 0.146838
     * Gncx_b in INaCa_i: 0.000971
     * Pnak_b in INaK: 67.911261
     * GKb_b in IKb: 0.003674
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.038959
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11762533, states[0] = -94.915011, states[40]= 0.000000
Saving checkpoint... 
Iteration: 24417868, states[0] = -94.973165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 36911247, states[0] = -94.951629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 49508455, states[0] = 24.244200, states[40]= 0.075621
Saving checkpoint... 
Iteration: 62099465, states[0] = -19.468727, states[40]= 0.001009
Saving checkpoint... 
Iteration: 74646216, states[0] = -66.463110, states[40]= 0.000002
Saving checkpoint... 
Iteration: 87097745, states[0] = -17.370097, states[40]= 0.001189
Saving checkpoint... 
Iteration: 99160922, states[0] = -86.708307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 111487083, states[0] = -94.931897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 124355928, states[0] = -94.893794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 136403816, states[0] = -94.911688, states[40]= 0.000000
Saving checkpoint... 
Iteration: 149405442, states[0] = -94.911500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 161380086, states[0] = -94.902297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 173933784, states[0] = -94.918327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 185755331, states[0] = -94.806700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 197825479, states[0] = -94.873680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 209896377, states[0] = -94.907327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 222178254, states[0] = -94.551478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 234657939, states[0] = -81.598583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 247167952, states[0] = -92.796903, states[40]= 0.000000
Saving checkpoint... 
Iteration: 259348428, states[0] = -94.886865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 270727767, states[0] = -94.763640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 283095842, states[0] = -15.146581, states[40]= 0.001447
Saving checkpoint... 
Iteration: 295545763, states[0] = 13.436826, states[40]= 0.005120
Saving checkpoint... 
Iteration: 307865242, states[0] = -94.894955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 320745673, states[0] = -94.792489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 332744454, states[0] = -94.790667, states[40]= 0.000000
Saving checkpoint... 
Iteration: 345122981, states[0] = -40.946491, states[40]= 0.000112
Saving checkpoint... 
Iteration: 357523767, states[0] = 20.684264, states[40]= 0.007714
Saving checkpoint... 
Iteration: 370014265, states[0] = 22.646876, states[40]= 0.021478
Saving checkpoint... 
Iteration: 382728879, states[0] = -94.765468, states[40]= 0.000000
Saving checkpoint... 
Iteration: 394793566, states[0] = -94.848430, states[40]= 0.000000
Saving checkpoint... 
Iteration: 407335352, states[0] = -94.879371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 420031067, states[0] = 18.616815, states[40]= 0.006065
Saving checkpoint... 
Iteration: 432680655, states[0] = -94.610177, states[40]= 0.000000
Saving checkpoint... 
Iteration: 444972123, states[0] = -94.924946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 457596948, states[0] = -16.179469, states[40]= 0.001317
Saving checkpoint... 
Iteration: 470095982, states[0] = -15.275488, states[40]= 0.001430
Saving checkpoint... 
Iteration: 482682075, states[0] = -94.631791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 494938781, states[0] = -94.918526, states[40]= 0.000000
Saving checkpoint... 
Iteration: 507278030, states[0] = -94.833101, states[40]= 0.000000
Saving checkpoint... 
Iteration: 519805038, states[0] = -94.858173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 532028307, states[0] = 19.452220, states[40]= 0.006492
Saving checkpoint... 
Iteration: 544216828, states[0] = -94.743249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 556549607, states[0] = 11.959475, states[40]= 0.005037
Saving checkpoint... 
Iteration: 568791580, states[0] = -94.846504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 581197143, states[0] = -94.702050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 593470155, states[0] = -94.924531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 605681462, states[0] = -94.623262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 617981569, states[0] = -94.926311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 629862487, states[0] = -94.893493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 642099964, states[0] = -19.020472, states[40]= 0.001041
Saving checkpoint... 
Iteration: 654338525, states[0] = -94.881087, states[40]= 0.000000
Saving checkpoint... 
Iteration: 666649293, states[0] = -69.208951, states[40]= 0.000001
Saving checkpoint... 
Iteration: 679314483, states[0] = -94.865353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 691908867, states[0] = -94.910688, states[40]= 0.000000
Saving checkpoint... 
Iteration: 704196632, states[0] = -94.700780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 716479729, states[0] = -94.925975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 728552579, states[0] = 10.791030, states[40]= 0.004989
Saving checkpoint... 
Iteration: 741099484, states[0] = -18.567303, states[40]= 0.001077
Saving checkpoint... 
Iteration: 753482436, states[0] = -94.926357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 766308012, states[0] = -94.860388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 778605174, states[0] = -23.935827, states[40]= 0.000758
Saving checkpoint... 
Iteration: 790880209, states[0] = -94.900887, states[40]= 0.000000
Saving checkpoint... 
Iteration: 803389768, states[0] = -94.904426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 815955377, states[0] = -94.921762, states[40]= 0.000000
Saving checkpoint... 
Iteration: 828106702, states[0] = -25.376206, states[40]= 0.000691
Saving checkpoint... 
Iteration: 841172342, states[0] = -94.075941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 853779138, states[0] = -94.834059, states[40]= 0.000000
Saving checkpoint... 
Iteration: 866264438, states[0] = -94.817392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 878478858, states[0] = -94.925744, states[40]= 0.000000
Saving checkpoint... 
Iteration: 890963566, states[0] = -94.923221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 903188730, states[0] = -94.678150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 914946551, states[0] = -94.919943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 927814951, states[0] = -94.865544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 939814549, states[0] = -94.865242, states[40]= 0.000000
Saving checkpoint... 
Iteration: 951881786, states[0] = -94.901396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 964260937, states[0] = -94.812980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 976531693, states[0] = 18.419494, states[40]= 0.005987
Saving checkpoint... 
Iteration: 988791048, states[0] = -94.845753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1001290204, states[0] = -94.844957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1013659076, states[0] = -83.349513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1026203773, states[0] = -94.716440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1038866918, states[0] = -94.895237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1051757378, states[0] = -94.808340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1064555474, states[0] = 9.627581, states[40]= 0.004947
Saving checkpoint... 
Iteration: 1075320276, states[0] = -94.869246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1088165913, states[0] = -91.574636, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1100805079, states[0] = -94.857851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1112734125, states[0] = -94.773918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1124487333, states[0] = -94.926837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1137124410, states[0] = -42.364017, states[40]= 0.000091
Saving checkpoint... 
Iteration: 1147744600, states[0] = -94.790377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1159861174, states[0] = -94.892562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1172522651, states[0] = 20.957177, states[40]= 0.008202
Saving checkpoint... 
Iteration: 1185186231, states[0] = -94.666540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1197551974, states[0] = 11.030991, states[40]= 0.004998
Saving checkpoint... 
Iteration: 1210122183, states[0] = -40.159489, states[40]= 0.000126
Saving checkpoint... 
Iteration: 1221820176, states[0] = -94.869087, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1233867823, states[0] = -94.895515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1246169022, states[0] = -93.242118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1258738356, states[0] = -94.780689, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1271394570, states[0] = -94.905804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1283891373, states[0] = -94.904697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1295948560, states[0] = -94.920124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1307777342, states[0] = -94.831878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1320403531, states[0] = -94.908685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1332636803, states[0] = -55.149757, states[40]= 0.000011
Saving checkpoint... 
Iteration: 1345466322, states[0] = -94.923425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1357851342, states[0] = -94.887641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1370117297, states[0] = -35.423581, states[40]= 0.000246
Saving checkpoint... 
Iteration: 1382273025, states[0] = -94.827111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1394119872, states[0] = -37.904628, states[40]= 0.000175
Saving checkpoint... 
Iteration: 1406409176, states[0] = -94.910344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1418816576, states[0] = -94.866422, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1430831077, states[0] = -94.876135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1443600094, states[0] = -19.142745, states[40]= 0.001031
Saving checkpoint... 
Iteration: 1454818142, states[0] = -94.867519, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1467263631, states[0] = -94.816034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1479536621, states[0] = 16.778248, states[40]= 0.005530
Saving checkpoint... 
Iteration: 1491464846, states[0] = -94.923080, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1503207629, states[0] = -95.070473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1515344107, states[0] = 11.528346, states[40]= 0.005888
Saving checkpoint... 
Iteration: 1527470273, states[0] = -95.011160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1539508875, states[0] = -95.111688, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1551392200, states[0] = -28.053995, states[40]= 0.000554
Saving checkpoint... 
Iteration: 1563841706, states[0] = -95.176516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1576223818, states[0] = 19.943521, states[40]= 0.008886
Saving checkpoint... 
Iteration: 1588546096, states[0] = 9.878193, states[40]= 0.005807
Saving checkpoint... 
Iteration: 1600758882, states[0] = -95.204900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1613163687, states[0] = -0.527959, states[40]= 0.004722
Saving checkpoint... 
Iteration: 1624432346, states[0] = -95.173723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1636815736, states[0] = 22.503650, states[40]= 0.018335
Saving checkpoint... 
Iteration: 1649379619, states[0] = -95.227663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1662195562, states[0] = -95.109603, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1674416898, states[0] = -56.846229, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1686883607, states[0] = -95.231521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1699370689, states[0] = -95.048527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1710864453, states[0] = -95.214157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1722659863, states[0] = 1.980501, states[40]= 0.005080
Saving checkpoint... 
Iteration: 1735241772, states[0] = 11.995216, states[40]= 0.006037
Saving checkpoint... 
Iteration: 1747310735, states[0] = -49.561737, states[40]= 0.000031
Saving checkpoint... 
Iteration: 1759965794, states[0] = -95.032332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1772003619, states[0] = -95.126647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1784072160, states[0] = -95.221666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1796670098, states[0] = -95.219723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1808709659, states[0] = -94.782306, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1821463575, states[0] = -94.965838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1832891045, states[0] = -94.935677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1844534915, states[0] = 17.109425, states[40]= 0.005656
Saving checkpoint... 
Iteration: 1856610984, states[0] = -30.250603, states[40]= 0.000456
Saving checkpoint... 
Iteration: 1868771435, states[0] = -94.836327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1881239874, states[0] = -94.790638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1893259424, states[0] = -94.816056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1905462728, states[0] = -94.926295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1917638085, states[0] = -56.688685, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1929578480, states[0] = -1.492485, states[40]= 0.004043
Saving checkpoint... 
Iteration: 1941806901, states[0] = -94.860127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1954242437, states[0] = -94.787548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1965179706, states[0] = -94.591535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1977422146, states[0] = -94.914043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1989421734, states[0] = -94.913784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2001960227, states[0] = -94.922138, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2014050621, states[0] = 11.561259, states[40]= 0.005020
Saving checkpoint... 
Iteration: 2026176056, states[0] = -94.451470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2038372894, states[0] = -94.897221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2050447735, states[0] = -94.919505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2063028183, states[0] = 19.488206, states[40]= 0.006515
Saving checkpoint... 
Iteration: 2075232308, states[0] = -94.770272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2087740756, states[0] = -94.783917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2099990225, states[0] = -94.926607, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.803759
 - CaMKt in component CaMK (millimolar): 0.006907
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.612617
 - nass in component intracellular_ions (millimolar): 6.612676
 - ki in component intracellular_ions (millimolar): 145.366336
 - kss in component intracellular_ions (millimolar): 145.366317
 - cansr in component intracellular_ions (millimolar): 1.307121
 - cajsr in component intracellular_ions (millimolar): 1.269176
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003655
 - hf in component INa (dimensionless): 0.878288
 - hs in component INa (dimensionless): 0.878283
 - j in component INa (dimensionless): 0.878252
 - hsp in component INa (dimensionless): 0.722609
 - jp in component INa (dimensionless): 0.878230
 - mL in component INaL (dimensionless): 0.000051
 - hL in component INaL (dimensionless): 0.706685
 - hLp in component INaL (dimensionless): 0.447125
 - a in component Ito (dimensionless): 0.000628
 - iF in component Ito (dimensionless): 0.999867
 - iS in component Ito (dimensionless): 0.619074
 - ap in component Ito (dimensionless): 0.000320
 - iFp in component Ito (dimensionless): 0.999867
 - iSp in component Ito (dimensionless): 0.693190
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.934385
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999883
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001586
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.337920
 - xs1 in component IKs (dimensionless): 0.242787
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997363
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
19:39:55 (21068): called boinc_finish(0)

</stderr_txt>
]]>


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