𝕏

Task 55387981

Name HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_862_1
Workunit 26301043
Created 30 Jun 2024, 3:48:36 UTC
Sent 30 Jun 2024, 5:25:22 UTC
Report deadline 3 Jul 2024, 15:01:22 UTC
Received 3 Jul 2024, 3:31:09 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 213681
Run time 2 hours 45 min 33 sec
CPU time 2 hours 45 min 33 sec
Validate state Valid
Credit 62.03
Device peak FLOPS 3.69 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.16 MB
Peak swap size 6.22 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>8.0.3</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_862.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_862_1_r1182506623_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_862_1_r1182506623_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 93.340253
     * GNaL_b in INaL: 0.005807
     * Gto_b in Ito: 0.097462
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.029748
     * GKs_b in IKs: 0.001829
     * GK1_b in IK1: 0.153324
     * Gncx_b in INaCa_i: 0.000971
     * Pnak_b in INaK: 70.032737
     * GKb_b in IKb: 0.003822
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.021504
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12462069, states[0] = -94.934214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 25157027, states[0] = -70.421957, states[40]= 0.000001
Saving checkpoint... 
Iteration: 37694379, states[0] = -94.626025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 49777985, states[0] = -94.771365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 62293061, states[0] = -94.780073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 74658496, states[0] = -68.976332, states[40]= 0.000001
Saving checkpoint... 
Iteration: 87200581, states[0] = -94.618038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 99780351, states[0] = -94.755235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 112439251, states[0] = -94.845890, states[40]= 0.000000
Saving checkpoint... 
Iteration: 125118624, states[0] = -29.841167, states[40]= 0.000540
Saving checkpoint... 
Iteration: 137622387, states[0] = -33.045963, states[40]= 0.000379
Saving checkpoint... 
Iteration: 150156074, states[0] = -65.365036, states[40]= 0.000002
Saving checkpoint... 
Iteration: 162607709, states[0] = -20.433477, states[40]= 0.000980
Saving checkpoint... 
Iteration: 175394839, states[0] = -94.829151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 187482166, states[0] = -94.851341, states[40]= 0.000000
Saving checkpoint... 
Iteration: 200030793, states[0] = 18.571393, states[40]= 0.005241
Saving checkpoint... 
Iteration: 212805798, states[0] = -94.775857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 224769655, states[0] = -94.736889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 237683288, states[0] = -94.161591, states[40]= 0.000000
Saving checkpoint... 
Iteration: 249883178, states[0] = -94.823960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 262133148, states[0] = -42.514562, states[40]= 0.000101
Saving checkpoint... 
Iteration: 274707731, states[0] = -94.628128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 287195428, states[0] = -94.588628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 298763503, states[0] = -94.728544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 311086094, states[0] = -3.338354, states[40]= 0.003622
Saving checkpoint... 
Iteration: 322654286, states[0] = -63.309949, states[40]= 0.000003
Saving checkpoint... 
Iteration: 335259254, states[0] = -94.722558, states[40]= 0.000000
Saving checkpoint... 
Iteration: 348245140, states[0] = -94.700884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 360976009, states[0] = -94.849760, states[40]= 0.000000
Saving checkpoint... 
Iteration: 373880811, states[0] = -94.822791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 384798892, states[0] = -94.769152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 396937697, states[0] = -94.841652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 409651484, states[0] = -60.350508, states[40]= 0.000005
Saving checkpoint... 
Iteration: 422228448, states[0] = -94.671128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 434424883, states[0] = -94.838202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 446845210, states[0] = -94.804537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 459140073, states[0] = -49.040763, states[40]= 0.000037
Saving checkpoint... 
Iteration: 471358344, states[0] = -94.811962, states[40]= 0.000000
Saving checkpoint... 
Iteration: 484582212, states[0] = -1.033109, states[40]= 0.003993
Saving checkpoint... 
Iteration: 496920795, states[0] = -94.836969, states[40]= 0.000000
Saving checkpoint... 
Iteration: 509436167, states[0] = -94.841170, states[40]= 0.000000
Saving checkpoint... 
Iteration: 521770085, states[0] = -94.737059, states[40]= 0.000000
Saving checkpoint... 
Iteration: 533870615, states[0] = -94.818063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 546266020, states[0] = -94.731723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 558384116, states[0] = -94.824031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 571293837, states[0] = -94.764037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 583723809, states[0] = -94.661937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 594984986, states[0] = -94.851067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 607587332, states[0] = -4.128629, states[40]= 0.003476
Saving checkpoint... 
Iteration: 619604730, states[0] = -17.838447, states[40]= 0.001148
Saving checkpoint... 
Iteration: 631904769, states[0] = -94.831767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 644211155, states[0] = -94.635460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 656297961, states[0] = -94.768028, states[40]= 0.000000
Saving checkpoint... 
Iteration: 668504051, states[0] = 28.697359, states[40]= 0.182749
Saving checkpoint... 
Iteration: 680538998, states[0] = 16.221617, states[40]= 0.004792
Saving checkpoint... 
Iteration: 693105297, states[0] = -18.325550, states[40]= 0.001110
Saving checkpoint... 
Iteration: 705779989, states[0] = -94.748969, states[40]= 0.000000
Saving checkpoint... 
Iteration: 717915652, states[0] = -94.835233, states[40]= 0.000000
Saving checkpoint... 
Iteration: 729266756, states[0] = -94.732547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 742232657, states[0] = -94.678772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 754764183, states[0] = -94.729072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 766758030, states[0] = -94.720429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 779439432, states[0] = -94.841763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 791807408, states[0] = -94.776606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 804319858, states[0] = -94.786863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 815759527, states[0] = -94.722537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 828130438, states[0] = -40.045325, states[40]= 0.000146
Saving checkpoint... 
Iteration: 840188618, states[0] = -94.495978, states[40]= 0.000000
Saving checkpoint... 
Iteration: 852746478, states[0] = -94.702640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 864957857, states[0] = -94.845871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 877420535, states[0] = -94.836573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 889095448, states[0] = -10.034205, states[40]= 0.002267
Saving checkpoint... 
Iteration: 901241203, states[0] = -94.693818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 913601134, states[0] = -14.756015, states[40]= 0.001475
Saving checkpoint... 
Iteration: 925464521, states[0] = -94.847162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 937394586, states[0] = -94.827856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 949154799, states[0] = -63.865800, states[40]= 0.000003
Saving checkpoint... 
Iteration: 960837138, states[0] = -94.799035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 972751199, states[0] = -94.710024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 985231614, states[0] = -94.676632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 997680166, states[0] = -93.572867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1009854038, states[0] = -94.809172, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1021797536, states[0] = -94.767310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1034528538, states[0] = 19.133168, states[40]= 0.005483
Saving checkpoint... 
Iteration: 1046280358, states[0] = -94.749109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1058572468, states[0] = 3.858455, states[40]= 0.004488
Saving checkpoint... 
Iteration: 1071005273, states[0] = 25.136605, states[40]= 0.158422
Saving checkpoint... 
Iteration: 1083058975, states[0] = 9.374459, states[40]= 0.004661
Saving checkpoint... 
Iteration: 1095799475, states[0] = -94.769108, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1108294964, states[0] = -94.764712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1120796452, states[0] = -94.766170, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1133035423, states[0] = 17.298815, states[40]= 0.004930
Saving checkpoint... 
Iteration: 1145223345, states[0] = -94.660537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1157467163, states[0] = -94.847476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1169687932, states[0] = -94.474560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1181911480, states[0] = -94.833530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1194044339, states[0] = 14.505910, states[40]= 0.004690
Saving checkpoint... 
Iteration: 1206407971, states[0] = -94.832364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1218649344, states[0] = -58.162080, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1231051833, states[0] = 11.954257, states[40]= 0.004661
Saving checkpoint... 
Iteration: 1242388276, states[0] = -94.825152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1254463493, states[0] = -94.846684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1267199775, states[0] = -94.606418, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1278823606, states[0] = -94.789314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1290639872, states[0] = -48.846630, states[40]= 0.000038
Saving checkpoint... 
Iteration: 1302350591, states[0] = -94.806983, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1314945136, states[0] = -94.842686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1326577758, states[0] = 1.335587, states[40]= 0.004281
Saving checkpoint... 
Iteration: 1338997928, states[0] = -94.852396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1350697900, states[0] = -94.599598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1363194018, states[0] = -94.578240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1375252793, states[0] = -94.712134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1387676995, states[0] = -92.240461, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1399317396, states[0] = -94.784432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1411288349, states[0] = -94.757654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1423869405, states[0] = -94.816741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1435999513, states[0] = -94.852538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1447947084, states[0] = -94.843027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1459770126, states[0] = -94.736321, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1472056199, states[0] = 10.397867, states[40]= 0.004663
Saving checkpoint... 
Iteration: 1484493434, states[0] = -94.851624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1496373168, states[0] = -94.818447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1508692346, states[0] = -95.090663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1520550661, states[0] = -90.854557, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1532265560, states[0] = -94.850115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1543348295, states[0] = -89.653111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1555474132, states[0] = -95.115268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1566528326, states[0] = -95.059947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1578679352, states[0] = -10.846468, states[40]= 0.002412
Saving checkpoint... 
Iteration: 1591332119, states[0] = -66.668648, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1603322686, states[0] = -55.569936, states[40]= 0.000013
Saving checkpoint... 
Iteration: 1615742470, states[0] = -95.089460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1628104271, states[0] = 29.256965, states[40]= 0.157800
Saving checkpoint... 
Iteration: 1638918851, states[0] = 20.710879, states[40]= 0.010657
Saving checkpoint... 
Iteration: 1650950017, states[0] = 8.595400, states[40]= 0.005405
Saving checkpoint... 
Iteration: 1663366604, states[0] = -94.906333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1675726577, states[0] = -95.066502, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1687937552, states[0] = -74.620550, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1700665007, states[0] = -95.119406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1712863381, states[0] = -94.864998, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1725395103, states[0] = -26.837472, states[40]= 0.000664
Saving checkpoint... 
Iteration: 1737180938, states[0] = -94.966970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1749316533, states[0] = 21.182819, states[40]= 0.014130
Saving checkpoint... 
Iteration: 1761398335, states[0] = -30.065976, states[40]= 0.000502
Saving checkpoint... 
Iteration: 1773948907, states[0] = 9.127093, states[40]= 0.005429
Saving checkpoint... 
Iteration: 1784971162, states[0] = -95.125981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1797317124, states[0] = 21.068245, states[40]= 0.013027
Saving checkpoint... 
Iteration: 1809423837, states[0] = -94.890771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1821563894, states[0] = 6.748954, states[40]= 0.004649
Saving checkpoint... 
Iteration: 1833380943, states[0] = -94.850490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1846223573, states[0] = -94.680488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1858563188, states[0] = 7.522340, states[40]= 0.004644
Saving checkpoint... 
Iteration: 1871428227, states[0] = -94.847203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1883841527, states[0] = -94.807476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1896246835, states[0] = -94.706820, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1907543595, states[0] = 14.710158, states[40]= 0.004698
Saving checkpoint... 
Iteration: 1919651000, states[0] = -59.997653, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1932363334, states[0] = -94.814780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1944342664, states[0] = -94.802720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1956658996, states[0] = -68.740424, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1969717839, states[0] = -94.649050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1982164293, states[0] = -75.755107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1994325424, states[0] = -94.790222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2006829169, states[0] = -94.792830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2019218202, states[0] = -94.649365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2031741629, states[0] = -94.693590, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2044301036, states[0] = -94.769756, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2057013241, states[0] = 21.325569, states[40]= 0.023502
Saving checkpoint... 
Iteration: 2068714420, states[0] = -94.641269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2080777274, states[0] = -94.744561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2092899831, states[0] = -94.828745, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.727855
 - CaMKt in component CaMK (millimolar): 0.007603
 - cass in component intracellular_ions (millimolar): 0.000075
 - nai in component intracellular_ions (millimolar): 6.622435
 - nass in component intracellular_ions (millimolar): 6.622496
 - ki in component intracellular_ions (millimolar): 145.346373
 - kss in component intracellular_ions (millimolar): 145.346355
 - cansr in component intracellular_ions (millimolar): 1.343237
 - cajsr in component intracellular_ions (millimolar): 1.303752
 - cai in component intracellular_ions (millimolar): 0.000076
 - m in component INa (dimensionless): 0.003683
 - hf in component INa (dimensionless): 0.876949
 - hs in component INa (dimensionless): 0.876943
 - j in component INa (dimensionless): 0.876907
 - hsp in component INa (dimensionless): 0.720099
 - jp in component INa (dimensionless): 0.876884
 - mL in component INaL (dimensionless): 0.000051
 - hL in component INaL (dimensionless): 0.702124
 - hLp in component INaL (dimensionless): 0.437745
 - a in component Ito (dimensionless): 0.000631
 - iF in component Ito (dimensionless): 0.999866
 - iS in component Ito (dimensionless): 0.608833
 - ap in component Ito (dimensionless): 0.000321
 - iFp in component Ito (dimensionless): 0.999866
 - iSp in component Ito (dimensionless): 0.681530
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.931438
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999867
 - jca in component ICaL (dimensionless): 0.999973
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001714
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.330929
 - xs1 in component IKs (dimensionless): 0.253922
 - xs2 in component IKs (dimensionless): 0.000090
 - xk1 in component IK1 (dimensionless): 0.997383
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
20:30:34 (14144): called boinc_finish(0)

</stderr_txt>
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