𝕏

Task 55387972

Name HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_861_0
Workunit 26301039
Created 30 Jun 2024, 3:48:36 UTC
Sent 30 Jun 2024, 5:25:22 UTC
Report deadline 3 Jul 2024, 15:01:22 UTC
Received 3 Jul 2024, 0:21:19 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 213681
Run time 2 hours 58 min 31 sec
CPU time 2 hours 45 min 14 sec
Validate state Valid
Credit 62.55
Device peak FLOPS 3.69 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.13 MB
Peak swap size 6.21 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>8.0.3</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_861.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_861_0_r1509003268_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_861_0_r1509003268_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 101.056598
     * GNaL_b in INaL: 0.005823
     * Gto_b in Ito: 0.085541
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031055
     * GKs_b in IKs: 0.001803
     * GK1_b in IK1: 0.148691
     * Gncx_b in INaCa_i: 0.000978
     * Pnak_b in INaK: 70.274706
     * GKb_b in IKb: 0.003847
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.050726
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12914258, states[0] = -94.869667, states[40]= 0.000000
Saving checkpoint... 
Iteration: 24878738, states[0] = -94.827114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 37240633, states[0] = -94.696972, states[40]= 0.000000
Saving checkpoint... 
Iteration: 49434338, states[0] = -94.811108, states[40]= 0.000000
Saving checkpoint... 
Iteration: 61711425, states[0] = -94.625352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 74205928, states[0] = -94.608634, states[40]= 0.000000
Saving checkpoint... 
Iteration: 86725656, states[0] = -94.641338, states[40]= 0.000000
Saving checkpoint... 
Iteration: 99537917, states[0] = 16.101775, states[40]= 0.005291
Saving checkpoint... 
Iteration: 111862091, states[0] = -94.765481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 123835209, states[0] = -94.750688, states[40]= 0.000000
Saving checkpoint... 
Iteration: 136412688, states[0] = -94.780982, states[40]= 0.000000
Saving checkpoint... 
Iteration: 149407000, states[0] = -94.778763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 161862048, states[0] = -94.762266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 174535534, states[0] = 16.966849, states[40]= 0.005451
Saving checkpoint... 
Iteration: 186694051, states[0] = -94.569909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 199157474, states[0] = -77.119392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 211690983, states[0] = -94.559946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 224061880, states[0] = 7.066271, states[40]= 0.004735
Saving checkpoint... 
Iteration: 236883853, states[0] = -94.770063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 249453336, states[0] = -94.788127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 262048876, states[0] = 12.200615, states[40]= 0.004920
Saving checkpoint... 
Iteration: 274182239, states[0] = -94.476928, states[40]= 0.000000
Saving checkpoint... 
Iteration: 286467864, states[0] = -94.790541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 299146143, states[0] = -62.765050, states[40]= 0.000003
Saving checkpoint... 
Iteration: 312061788, states[0] = 7.107176, states[40]= 0.004737
Saving checkpoint... 
Iteration: 323504833, states[0] = 28.388771, states[40]= 0.145600
Saving checkpoint... 
Iteration: 335801547, states[0] = -94.724691, states[40]= 0.000000
Saving checkpoint... 
Iteration: 347806594, states[0] = -94.728649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 360164460, states[0] = -87.499131, states[40]= 0.000000
Saving checkpoint... 
Iteration: 372457066, states[0] = -94.788656, states[40]= 0.000000
Saving checkpoint... 
Iteration: 384904450, states[0] = -94.776545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 397408190, states[0] = -94.777613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 410161199, states[0] = -82.791243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 422184985, states[0] = -94.520658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 434644966, states[0] = -61.477076, states[40]= 0.000004
Saving checkpoint... 
Iteration: 446787674, states[0] = -94.712600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 458592335, states[0] = -10.948631, states[40]= 0.002099
Saving checkpoint... 
Iteration: 470639335, states[0] = -55.522529, states[40]= 0.000010
Saving checkpoint... 
Iteration: 482843461, states[0] = -94.752151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 495376619, states[0] = -94.767130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 507108795, states[0] = -25.951322, states[40]= 0.000656
Saving checkpoint... 
Iteration: 518871363, states[0] = -94.765051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 530433962, states[0] = -94.783984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 542124973, states[0] = -41.044574, states[40]= 0.000107
Saving checkpoint... 
Iteration: 554663923, states[0] = -86.786332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 567221259, states[0] = -94.624475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 579611130, states[0] = -28.098229, states[40]= 0.000553
Saving checkpoint... 
Iteration: 592006351, states[0] = 25.400437, states[40]= 0.116928
Saving checkpoint... 
Iteration: 604384826, states[0] = -94.770085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 616560193, states[0] = 7.769969, states[40]= 0.004763
Saving checkpoint... 
Iteration: 628843837, states[0] = -94.752260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 641518883, states[0] = 21.398319, states[40]= 0.010795
Saving checkpoint... 
Iteration: 653762272, states[0] = -94.685486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 666207964, states[0] = -94.599462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 677640040, states[0] = -56.255751, states[40]= 0.000009
Saving checkpoint... 
Iteration: 689014305, states[0] = 22.133039, states[40]= 0.020862
Saving checkpoint... 
Iteration: 701489299, states[0] = -94.793341, states[40]= 0.000000
Saving checkpoint... 
Iteration: 714124948, states[0] = -41.020327, states[40]= 0.000108
Saving checkpoint... 
Iteration: 726039031, states[0] = 15.783160, states[40]= 0.005229
Saving checkpoint... 
Iteration: 738578548, states[0] = -1.005432, states[40]= 0.004025
Saving checkpoint... 
Iteration: 751119828, states[0] = -36.156087, states[40]= 0.000217
Saving checkpoint... 
Iteration: 763953832, states[0] = -94.787834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 776762809, states[0] = -94.686057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 789261652, states[0] = -94.684652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 801551255, states[0] = 11.300898, states[40]= 0.004882
Saving checkpoint... 
Iteration: 815206198, states[0] = -94.595877, states[40]= 0.000000
Saving checkpoint... 
Iteration: 829564536, states[0] = 5.935133, states[40]= 0.004682
Saving checkpoint... 
Iteration: 844124979, states[0] = -41.050185, states[40]= 0.000107
Saving checkpoint... 
Iteration: 858597447, states[0] = -15.514165, states[40]= 0.001370
Saving checkpoint... 
Iteration: 873044384, states[0] = 13.867018, states[40]= 0.005020
Saving checkpoint... 
Iteration: 887878488, states[0] = -94.767599, states[40]= 0.000000
Saving checkpoint... 
Iteration: 902424667, states[0] = -94.781611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 916936454, states[0] = -94.784292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 931446090, states[0] = -94.786266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 945963779, states[0] = -94.789452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 960396445, states[0] = -94.773755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 974521675, states[0] = 20.848583, states[40]= 0.008487
Saving checkpoint... 
Iteration: 987883311, states[0] = -94.769310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1000989312, states[0] = -94.793160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1005966581, states[0] = -94.789873, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1016723573, states[0] = -94.628293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1023982631, states[0] = -94.792256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1031068175, states[0] = 4.310481, states[40]= 0.004585
Saving checkpoint... 
Iteration: 1031715198, states[0] = -94.613107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1039525270, states[0] = 20.011802, states[40]= 0.006995
Saving checkpoint... 
Iteration: 1052289999, states[0] = -94.714364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1063809434, states[0] = -94.730350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1075121357, states[0] = -37.593715, states[40]= 0.000177
Saving checkpoint... 
Iteration: 1086777556, states[0] = -94.702296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1096994658, states[0] = -94.793772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1107260858, states[0] = -94.683488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1118772331, states[0] = -94.696739, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1129688743, states[0] = -94.549276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1142455639, states[0] = -94.787930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1151789171, states[0] = -94.713548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1164394719, states[0] = -94.773080, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1176303440, states[0] = -94.725682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1186702810, states[0] = -94.588803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1197898227, states[0] = -94.774169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1209248212, states[0] = -94.666891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1220903897, states[0] = -94.775871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1232066436, states[0] = 5.098333, states[40]= 0.004636
Saving checkpoint... 
Iteration: 1243700825, states[0] = -94.584635, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1256041697, states[0] = 14.840747, states[40]= 0.005109
Saving checkpoint... 
Iteration: 1268772371, states[0] = -94.696690, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1279206950, states[0] = -94.597084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1291099710, states[0] = -17.591941, states[40]= 0.001143
Saving checkpoint... 
Iteration: 1302139281, states[0] = -55.465776, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1314422078, states[0] = -94.780727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1323855458, states[0] = -94.757627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1335857032, states[0] = -94.758355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1348214981, states[0] = -94.612506, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1360100659, states[0] = -18.466372, states[40]= 0.001066
Saving checkpoint... 
Iteration: 1370797797, states[0] = -94.720969, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1383145062, states[0] = -61.580363, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1395496984, states[0] = -94.793871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1408177192, states[0] = -94.243853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1419223956, states[0] = -94.628716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1431833177, states[0] = -94.745838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1443707144, states[0] = -94.597367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1455889513, states[0] = -94.771185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1466264731, states[0] = -94.687919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1476593014, states[0] = -11.537358, states[40]= 0.001989
Saving checkpoint... 
Iteration: 1489683299, states[0] = -94.496584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1502283004, states[0] = -94.889961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1514419436, states[0] = 21.379553, states[40]= 0.011820
Saving checkpoint... 
Iteration: 1524837568, states[0] = -95.013179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1537269234, states[0] = -3.763729, states[40]= 0.004020
Saving checkpoint... 
Iteration: 1549181840, states[0] = -95.079412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1561097767, states[0] = -94.972505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1573203790, states[0] = 33.436292, states[40]= 0.122689
Saving checkpoint... 
Iteration: 1586068486, states[0] = -95.079900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1598789133, states[0] = -24.410095, states[40]= 0.000736
Saving checkpoint... 
Iteration: 1610737591, states[0] = 13.906903, states[40]= 0.006162
Saving checkpoint... 
Iteration: 1623448271, states[0] = -93.862267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1635971632, states[0] = -6.501794, states[40]= 0.003419
Saving checkpoint... 
Iteration: 1647631138, states[0] = 16.748663, states[40]= 0.006838
Saving checkpoint... 
Iteration: 1660042471, states[0] = -90.408616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1672080284, states[0] = -94.945197, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1684454576, states[0] = -95.070790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1696965553, states[0] = -94.901621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1708924643, states[0] = -64.429686, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1721147660, states[0] = 8.955001, states[40]= 0.005604
Saving checkpoint... 
Iteration: 1733338650, states[0] = -95.051875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1745951047, states[0] = -95.066990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1758185473, states[0] = -94.957699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1770357660, states[0] = 3.472689, states[40]= 0.005146
Saving checkpoint... 
Iteration: 1782613439, states[0] = 22.625575, states[40]= 0.026150
Saving checkpoint... 
Iteration: 1795206440, states[0] = 26.452499, states[40]= 0.106303
Saving checkpoint... 
Iteration: 1807926153, states[0] = -94.840057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1819601116, states[0] = -21.058944, states[40]= 0.000898
Saving checkpoint... 
Iteration: 1832312156, states[0] = -94.762745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1845004406, states[0] = 29.614760, states[40]= 0.151578
Saving checkpoint... 
Iteration: 1857794527, states[0] = -94.732408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1869908659, states[0] = -94.786844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1882364930, states[0] = -94.768427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1894407533, states[0] = -94.781294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1906660037, states[0] = -81.328926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1919216238, states[0] = -94.616803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1931778974, states[0] = -94.704785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1944150141, states[0] = -67.415523, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1956829177, states[0] = -94.743828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1969158615, states[0] = -78.855165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1980738606, states[0] = -94.652705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1993184912, states[0] = -94.519188, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2005383883, states[0] = -94.769016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2017954754, states[0] = -94.787303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2030394708, states[0] = -94.772577, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2042684516, states[0] = -94.514078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2055344531, states[0] = -94.751737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2067713724, states[0] = -94.609670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2079665644, states[0] = -88.937335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2092240760, states[0] = -94.655534, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.669626
 - CaMKt in component CaMK (millimolar): 0.006829
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.625155
 - nass in component intracellular_ions (millimolar): 6.625212
 - ki in component intracellular_ions (millimolar): 145.356439
 - kss in component intracellular_ions (millimolar): 145.356421
 - cansr in component intracellular_ions (millimolar): 1.294871
 - cajsr in component intracellular_ions (millimolar): 1.256813
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003704
 - hf in component INa (dimensionless): 0.875913
 - hs in component INa (dimensionless): 0.875908
 - j in component INa (dimensionless): 0.875878
 - hsp in component INa (dimensionless): 0.718172
 - jp in component INa (dimensionless): 0.875857
 - mL in component INaL (dimensionless): 0.000052
 - hL in component INaL (dimensionless): 0.702655
 - hLp in component INaL (dimensionless): 0.441787
 - a in component Ito (dimensionless): 0.000633
 - iF in component Ito (dimensionless): 0.999864
 - iS in component Ito (dimensionless): 0.616123
 - ap in component Ito (dimensionless): 0.000323
 - iFp in component Ito (dimensionless): 0.999864
 - iSp in component Ito (dimensionless): 0.689715
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.934354
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999881
 - jca in component ICaL (dimensionless): 0.999977
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001524
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.335255
 - xs1 in component IKs (dimensionless): 0.244725
 - xs2 in component IKs (dimensionless): 0.000090
 - xk1 in component IK1 (dimensionless): 0.997398
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
17:20:44 (14564): called boinc_finish(0)

</stderr_txt>
]]>


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