𝕏

Task 55387952

Name HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_759_0
Workunit 26301029
Created 30 Jun 2024, 3:48:36 UTC
Sent 30 Jun 2024, 5:25:22 UTC
Report deadline 3 Jul 2024, 15:01:22 UTC
Received 2 Jul 2024, 23:16:13 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 213681
Run time 2 hours 51 min 32 sec
CPU time 2 hours 45 min 25 sec
Validate state Valid
Credit 64.29
Device peak FLOPS 3.69 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.12 MB
Peak swap size 6.22 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>8.0.3</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_759.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_759_0_r164499830_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_759_0_r164499830_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 95.660445
     * GNaL_b in INaL: 0.005206
     * Gto_b in Ito: 0.072969
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.029862
     * GKs_b in IKs: 0.001805
     * GK1_b in IK1: 0.171760
     * Gncx_b in INaCa_i: 0.000956
     * Pnak_b in INaK: 70.879840
     * GKb_b in IKb: 0.003822
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.023715
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 13657097, states[0] = -91.109224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 27364211, states[0] = -95.044650, states[40]= 0.000000
Saving checkpoint... 
Iteration: 41066422, states[0] = 4.229434, states[40]= 0.004788
Saving checkpoint... 
Iteration: 54326371, states[0] = -94.997479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 67959101, states[0] = -95.034199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 81350351, states[0] = -94.998110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 94754709, states[0] = -94.921885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 108381886, states[0] = -95.005500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 121906701, states[0] = -95.011702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 135651402, states[0] = -71.810514, states[40]= 0.000001
Saving checkpoint... 
Iteration: 149296162, states[0] = -94.957008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 162729340, states[0] = -94.881845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 176246278, states[0] = -94.905473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 189847119, states[0] = -94.987472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 203007903, states[0] = 25.818450, states[40]= 0.083202
Saving checkpoint... 
Iteration: 216570497, states[0] = 3.066028, states[40]= 0.004662
Saving checkpoint... 
Iteration: 229765619, states[0] = -94.927759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 243588469, states[0] = -8.258430, states[40]= 0.002732
Saving checkpoint... 
Iteration: 257311832, states[0] = -94.967062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 270586219, states[0] = -6.493610, states[40]= 0.003117
Saving checkpoint... 
Iteration: 284233290, states[0] = -94.886838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 297819553, states[0] = -94.971985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 311532294, states[0] = 18.601019, states[40]= 0.006025
Saving checkpoint... 
Iteration: 325234951, states[0] = -94.889225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 338861395, states[0] = -94.993345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 352523515, states[0] = 21.288088, states[40]= 0.007884
Saving checkpoint... 
Iteration: 366191551, states[0] = -94.812575, states[40]= 0.000000
Saving checkpoint... 
Iteration: 379885662, states[0] = -95.002342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 393304383, states[0] = -94.961737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 406544988, states[0] = 13.957712, states[40]= 0.005250
Saving checkpoint... 
Iteration: 420177217, states[0] = -94.734211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 433426167, states[0] = -95.013496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 446787053, states[0] = -94.948045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 459740666, states[0] = -94.897202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 473298218, states[0] = -94.957096, states[40]= 0.000000
Saving checkpoint... 
Iteration: 486862701, states[0] = -94.993788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 500372531, states[0] = -94.997637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 513887820, states[0] = -95.002965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 527583757, states[0] = -4.691744, states[40]= 0.003500
Saving checkpoint... 
Iteration: 541171616, states[0] = -94.458732, states[40]= 0.000000
Saving checkpoint... 
Iteration: 554810450, states[0] = -94.965887, states[40]= 0.000000
Saving checkpoint... 
Iteration: 568480131, states[0] = -95.023096, states[40]= 0.000000
Saving checkpoint... 
Iteration: 582061389, states[0] = 7.284414, states[40]= 0.004942
Saving checkpoint... 
Iteration: 595736859, states[0] = -94.891792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 609307369, states[0] = -94.963726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 622962534, states[0] = -95.020417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 636554240, states[0] = 10.288801, states[40]= 0.005064
Saving checkpoint... 
Iteration: 648927101, states[0] = -95.013574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 661680477, states[0] = -94.773479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 673698783, states[0] = -94.827088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 686661771, states[0] = -88.895657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 699515277, states[0] = 23.241288, states[40]= 0.017717
Saving checkpoint... 
Iteration: 711676184, states[0] = -94.711706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 723643289, states[0] = -61.068017, states[40]= 0.000004
Saving checkpoint... 
Iteration: 735895658, states[0] = -95.005281, states[40]= 0.000000
Saving checkpoint... 
Iteration: 748249483, states[0] = -94.908605, states[40]= 0.000000
Saving checkpoint... 
Iteration: 760437407, states[0] = -95.015725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 772934220, states[0] = -95.015053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 785790683, states[0] = -94.950893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 798137696, states[0] = -54.858557, states[40]= 0.000013
Saving checkpoint... 
Iteration: 809867292, states[0] = -94.995433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 822047369, states[0] = 13.031405, states[40]= 0.005189
Saving checkpoint... 
Iteration: 834307371, states[0] = -94.963587, states[40]= 0.000000
Saving checkpoint... 
Iteration: 847074548, states[0] = 0.972665, states[40]= 0.004441
Saving checkpoint... 
Iteration: 858905037, states[0] = -95.007917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 871639633, states[0] = -56.960556, states[40]= 0.000009
Saving checkpoint... 
Iteration: 884602103, states[0] = -20.414559, states[40]= 0.000966
Saving checkpoint... 
Iteration: 896301046, states[0] = -94.958973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 908913548, states[0] = -95.010151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 920942018, states[0] = -95.016552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 933310611, states[0] = -94.965760, states[40]= 0.000000
Saving checkpoint... 
Iteration: 945743462, states[0] = -94.900682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 958394755, states[0] = -95.004869, states[40]= 0.000000
Saving checkpoint... 
Iteration: 971009858, states[0] = 24.704793, states[40]= 0.053086
Saving checkpoint... 
Iteration: 983164999, states[0] = -92.261908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 995969083, states[0] = -95.021220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1009058789, states[0] = 8.399949, states[40]= 0.004991
Saving checkpoint... 
Iteration: 1021142563, states[0] = -60.233452, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1033819273, states[0] = -94.971334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1046559703, states[0] = 8.011204, states[40]= 0.004975
Saving checkpoint... 
Iteration: 1059539741, states[0] = 15.950351, states[40]= 0.005454
Saving checkpoint... 
Iteration: 1071889937, states[0] = -95.003298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1084371415, states[0] = -94.996853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1096897997, states[0] = -95.005755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1108794399, states[0] = -94.953711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1120757396, states[0] = -94.917927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1132743541, states[0] = -94.900670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1145216839, states[0] = -94.860032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1157322069, states[0] = -94.972977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1170223280, states[0] = -94.870762, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1182809173, states[0] = -94.964621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1195220773, states[0] = -94.866636, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1207065995, states[0] = 5.224033, states[40]= 0.004828
Saving checkpoint... 
Iteration: 1219510072, states[0] = 24.618125, states[40]= 0.050540
Saving checkpoint... 
Iteration: 1231785357, states[0] = -94.946086, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1243555404, states[0] = 9.812161, states[40]= 0.005046
Saving checkpoint... 
Iteration: 1255922598, states[0] = -95.012157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1268450053, states[0] = -95.017860, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1280658587, states[0] = -83.739799, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1293111297, states[0] = -28.891036, states[40]= 0.000546
Saving checkpoint... 
Iteration: 1304890471, states[0] = -95.003322, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1316857424, states[0] = -94.991047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1328138517, states[0] = -55.744194, states[40]= 0.000011
Saving checkpoint... 
Iteration: 1340268827, states[0] = -94.930305, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1353076764, states[0] = -0.260000, states[40]= 0.004280
Saving checkpoint... 
Iteration: 1365712509, states[0] = -94.852329, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1378454663, states[0] = -95.018617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1390361449, states[0] = -94.992707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1403111688, states[0] = -29.252533, states[40]= 0.000527
Saving checkpoint... 
Iteration: 1415324704, states[0] = -94.974394, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1427885760, states[0] = -95.001720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1441097272, states[0] = -15.959536, states[40]= 0.001362
Saving checkpoint... 
Iteration: 1455075326, states[0] = 0.547723, states[40]= 0.004388
Saving checkpoint... 
Iteration: 1469599150, states[0] = -17.688211, states[40]= 0.001176
Saving checkpoint... 
Iteration: 1484058600, states[0] = 8.480021, states[40]= 0.004994
Saving checkpoint... 
Iteration: 1498188241, states[0] = -94.804333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1513208242, states[0] = 26.713273, states[40]= 0.073153
Saving checkpoint... 
Iteration: 1527727317, states[0] = -66.228992, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1542174292, states[0] = -95.100926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1556574485, states[0] = -95.107453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1571018790, states[0] = -95.195783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1585533380, states[0] = 16.403531, states[40]= 0.006849
Saving checkpoint... 
Iteration: 1599895902, states[0] = -95.277319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1613428440, states[0] = 18.534873, states[40]= 0.007601
Saving checkpoint... 
Iteration: 1626618370, states[0] = 22.335951, states[40]= 0.013096
Saving checkpoint... 
Iteration: 1636447233, states[0] = -95.238001, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1647197899, states[0] = -95.166988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1647606003, states[0] = 29.086679, states[40]= 0.112398
Saving checkpoint... 
Iteration: 1657765207, states[0] = -95.256129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1662617909, states[0] = 22.482163, states[40]= 0.013742
Saving checkpoint... 
Iteration: 1673157038, states[0] = 4.097563, states[40]= 0.005385
Saving checkpoint... 
Iteration: 1673772382, states[0] = -7.014804, states[40]= 0.003388
Saving checkpoint... 
Iteration: 1683768114, states[0] = -95.102160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1691694099, states[0] = -95.278589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1703026288, states[0] = -95.213076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1710938501, states[0] = 13.936029, states[40]= 0.006369
Saving checkpoint... 
Iteration: 1723549067, states[0] = 8.563824, states[40]= 0.005779
Saving checkpoint... 
Iteration: 1728380576, states[0] = -15.213096, states[40]= 0.001637
Saving checkpoint... 
Iteration: 1738393568, states[0] = -95.159194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1748875434, states[0] = -95.120269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1756581014, states[0] = -15.678679, states[40]= 0.001566
Saving checkpoint... 
Iteration: 1767999501, states[0] = -35.375629, states[40]= 0.000258
Saving checkpoint... 
Iteration: 1774879531, states[0] = -14.112709, states[40]= 0.001819
Saving checkpoint... 
Iteration: 1785860512, states[0] = -95.252132, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1798030911, states[0] = -74.621260, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1808738972, states[0] = -94.932923, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1817666510, states[0] = -94.190076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1827813452, states[0] = -94.993190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1837235275, states[0] = -94.908986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1845187980, states[0] = -94.819738, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1854886929, states[0] = -95.013750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1866294587, states[0] = -94.961975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1878807298, states[0] = -94.968806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1888461473, states[0] = -95.023867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1899978731, states[0] = -95.025207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1910384450, states[0] = -95.003287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1922352401, states[0] = -94.990061, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1933501886, states[0] = 45.367875, states[40]= 0.089474
Saving checkpoint... 
Iteration: 1944918955, states[0] = -95.011663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1956456244, states[0] = -95.019093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1965616727, states[0] = -33.965882, states[40]= 0.000311
Saving checkpoint... 
Iteration: 1978500727, states[0] = 41.529386, states[40]= 0.008951
Saving checkpoint... 
Iteration: 1988361352, states[0] = -94.992483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1999907444, states[0] = -95.007984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2011752673, states[0] = -94.911829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2023476714, states[0] = -95.021742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2034266539, states[0] = -94.927491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2045546818, states[0] = 13.246247, states[40]= 0.005202
Saving checkpoint... 
Iteration: 2057228648, states[0] = -94.878675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2069047324, states[0] = 13.048878, states[40]= 0.005190
Saving checkpoint... 
Iteration: 2081286403, states[0] = -94.946425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2092964122, states[0] = -95.019716, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.900479
 - CaMKt in component CaMK (millimolar): 0.007008
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.546024
 - nass in component intracellular_ions (millimolar): 6.546082
 - ki in component intracellular_ions (millimolar): 145.430828
 - kss in component intracellular_ions (millimolar): 145.430810
 - cansr in component intracellular_ions (millimolar): 1.316179
 - cajsr in component intracellular_ions (millimolar): 1.278126
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003619
 - hf in component INa (dimensionless): 0.879977
 - hs in component INa (dimensionless): 0.879972
 - j in component INa (dimensionless): 0.879944
 - hsp in component INa (dimensionless): 0.725786
 - jp in component INa (dimensionless): 0.879925
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.709431
 - hLp in component INaL (dimensionless): 0.450647
 - a in component Ito (dimensionless): 0.000624
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.619200
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.693498
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.932959
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999878
 - jca in component ICaL (dimensionless): 0.999977
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001626
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.337504
 - xs1 in component IKs (dimensionless): 0.244184
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997338
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
16:15:33 (1856): called boinc_finish(0)

</stderr_txt>
]]>


CoMBA Research Group Logo
University San Jorge Logo

©2024 Universidad San Jorge