𝕏

Task 55387905

Name HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_954_0
Workunit 26301006
Created 30 Jun 2024, 3:48:31 UTC
Sent 30 Jun 2024, 5:27:07 UTC
Report deadline 3 Jul 2024, 15:03:07 UTC
Received 30 Jun 2024, 7:43:02 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 230332
Run time 2 hours 15 min 33 sec
CPU time 2 hours 13 min 30 sec
Validate state Valid
Credit 59.81
Device peak FLOPS 3.58 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 5.83 MB
Peak swap size 1.43 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_954.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_954_0_r264567615_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_954_0_r264567615_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 112.854157
     * GNaL_b in INaL: 0.005854
     * Gto_b in Ito: 0.086292
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.029909
     * GKs_b in IKs: 0.002025
     * GK1_b in IK1: 0.147138
     * Gncx_b in INaCa_i: 0.000972
     * Pnak_b in INaK: 74.258628
     * GKb_b in IKb: 0.003752
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.038462
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 17268065, states[0] = -94.800361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 34429325, states[0] = -94.845648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 51656609, states[0] = -75.884072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 68950422, states[0] = -94.812146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 86163506, states[0] = -84.138999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 103305648, states[0] = -94.736352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 120580126, states[0] = -1.668075, states[40]= 0.003965
Saving checkpoint... 
Iteration: 137758128, states[0] = -94.681903, states[40]= 0.000000
Saving checkpoint... 
Iteration: 154995868, states[0] = -94.801557, states[40]= 0.000000
Saving checkpoint... 
Iteration: 172317377, states[0] = -94.739358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 189493576, states[0] = -94.800314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 206771309, states[0] = -94.696103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 224010781, states[0] = 22.926917, states[40]= 0.045086
Saving checkpoint... 
Iteration: 241287928, states[0] = -94.713631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 258463966, states[0] = -94.795280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 275714802, states[0] = -94.608222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 292944231, states[0] = -94.791375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 310198888, states[0] = -94.574425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 327475681, states[0] = -94.797142, states[40]= 0.000000
Saving checkpoint... 
Iteration: 344615596, states[0] = -31.107751, states[40]= 0.000425
Saving checkpoint... 
Iteration: 361823011, states[0] = -94.742378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 379055667, states[0] = 9.800670, states[40]= 0.004891
Saving checkpoint... 
Iteration: 396285997, states[0] = -94.711520, states[40]= 0.000000
Saving checkpoint... 
Iteration: 413589417, states[0] = -7.920493, states[40]= 0.002736
Saving checkpoint... 
Iteration: 430801352, states[0] = -94.725702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 448088310, states[0] = -7.066337, states[40]= 0.002919
Saving checkpoint... 
Iteration: 465319438, states[0] = -94.739812, states[40]= 0.000000
Saving checkpoint... 
Iteration: 482625654, states[0] = -40.345308, states[40]= 0.000123
Saving checkpoint... 
Iteration: 499841024, states[0] = -94.753635, states[40]= 0.000000
Saving checkpoint... 
Iteration: 517132886, states[0] = -47.325503, states[40]= 0.000042
Saving checkpoint... 
Iteration: 534362608, states[0] = -94.764811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 551682571, states[0] = -94.413191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 568895761, states[0] = -94.778022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 586087881, states[0] = -6.742292, states[40]= 0.002988
Saving checkpoint... 
Iteration: 603334949, states[0] = -94.749970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 620541872, states[0] = 14.938998, states[40]= 0.005187
Saving checkpoint... 
Iteration: 637765625, states[0] = -94.688741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 654979648, states[0] = -94.797552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 672189099, states[0] = -94.534158, states[40]= 0.000000
Saving checkpoint... 
Iteration: 689480617, states[0] = -94.797677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 706727437, states[0] = -94.631576, states[40]= 0.000000
Saving checkpoint... 
Iteration: 723867955, states[0] = -94.767126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 741124445, states[0] = -39.211686, states[40]= 0.000146
Saving checkpoint... 
Iteration: 758361595, states[0] = -94.764201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 775585644, states[0] = -5.117942, states[40]= 0.003328
Saving checkpoint... 
Iteration: 792769308, states[0] = -94.693096, states[40]= 0.000000
Saving checkpoint... 
Iteration: 809958396, states[0] = -94.793873, states[40]= 0.000000
Saving checkpoint... 
Iteration: 827241158, states[0] = -94.654484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 844496306, states[0] = -94.799772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 861641670, states[0] = -56.141505, states[40]= 0.000010
Saving checkpoint... 
Iteration: 878842484, states[0] = -94.754240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 896123320, states[0] = -38.164524, states[40]= 0.000169
Saving checkpoint... 
Iteration: 913365306, states[0] = -94.765824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 930616827, states[0] = -32.222122, states[40]= 0.000374
Saving checkpoint... 
Iteration: 947865026, states[0] = -94.765676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 964966493, states[0] = -94.795234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 982288192, states[0] = -94.713335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 999547764, states[0] = 12.800497, states[40]= 0.005014
Saving checkpoint... 
Iteration: 1016788085, states[0] = -94.713209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1033961612, states[0] = -94.794329, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1051112540, states[0] = -28.346874, states[40]= 0.000561
Saving checkpoint... 
Iteration: 1068299387, states[0] = -94.723621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1085541277, states[0] = 15.149583, states[40]= 0.005212
Saving checkpoint... 
Iteration: 1102847393, states[0] = -94.756824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1120086239, states[0] = -5.539123, states[40]= 0.003241
Saving checkpoint... 
Iteration: 1137338369, states[0] = -94.751703, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1154581096, states[0] = -2.142588, states[40]= 0.003884
Saving checkpoint... 
Iteration: 1171789428, states[0] = -94.714420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1188981066, states[0] = -94.797445, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1206125086, states[0] = -39.811247, states[40]= 0.000133
Saving checkpoint... 
Iteration: 1223406735, states[0] = -94.781162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1240691523, states[0] = -94.549143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1257928317, states[0] = -94.787100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1275202080, states[0] = -94.581280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1292508912, states[0] = 23.608409, states[40]= 0.069237
Saving checkpoint... 
Iteration: 1309722571, states[0] = -94.622374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1326910623, states[0] = -94.782265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1344136687, states[0] = -51.108563, states[40]= 0.000023
Saving checkpoint... 
Iteration: 1361463402, states[0] = -94.794454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1378795123, states[0] = -94.719634, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1396024061, states[0] = 20.395892, states[40]= 0.007583
Saving checkpoint... 
Iteration: 1413311577, states[0] = -94.733412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1430503826, states[0] = 32.924374, states[40]= 0.144926
Saving checkpoint... 
Iteration: 1447763292, states[0] = -94.685346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1464973725, states[0] = -94.796139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1482200738, states[0] = -94.578109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1499361008, states[0] = -94.763478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1516391719, states[0] = -94.927223, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1533523346, states[0] = -95.006311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1550672801, states[0] = -95.080070, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1567861094, states[0] = 1.878344, states[40]= 0.005005
Saving checkpoint... 
Iteration: 1585049038, states[0] = -93.396611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1602176121, states[0] = -94.933121, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1619370923, states[0] = -95.092957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1636609232, states[0] = -44.761433, states[40]= 0.000065
Saving checkpoint... 
Iteration: 1653761785, states[0] = -94.861706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1670864737, states[0] = -94.890827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1687976176, states[0] = -94.936081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1705068781, states[0] = -94.912548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1722236227, states[0] = -95.054209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1739357822, states[0] = -95.081081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1756486394, states[0] = -95.108129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1773664701, states[0] = -0.660466, states[40]= 0.004650
Saving checkpoint... 
Iteration: 1790758433, states[0] = 3.308007, states[40]= 0.005173
Saving checkpoint... 
Iteration: 1807881951, states[0] = -94.831385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1825094350, states[0] = -13.685962, states[40]= 0.001657
Saving checkpoint... 
Iteration: 1842291078, states[0] = -94.738510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1859430609, states[0] = -94.800790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1876569493, states[0] = 3.811331, states[40]= 0.004604
Saving checkpoint... 
Iteration: 1893640032, states[0] = -54.770244, states[40]= 0.000012
Saving checkpoint... 
Iteration: 1910797990, states[0] = -94.724726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1927949074, states[0] = -94.793038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1945161222, states[0] = -79.625862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1962250751, states[0] = -94.668755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1979369081, states[0] = -94.767182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1996348484, states[0] = -94.757043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2013447748, states[0] = -94.791140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2030559288, states[0] = 8.362127, states[40]= 0.004842
Saving checkpoint... 
Iteration: 2047745744, states[0] = -94.660791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2064930823, states[0] = -94.787210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2082076587, states[0] = 0.437306, states[40]= 0.004261
Saving checkpoint... 
Iteration: 2099180287, states[0] = -94.294356, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.675323
 - CaMKt in component CaMK (millimolar): 0.006899
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.510864
 - nass in component intracellular_ions (millimolar): 6.510923
 - ki in component intracellular_ions (millimolar): 145.469199
 - kss in component intracellular_ions (millimolar): 145.469180
 - cansr in component intracellular_ions (millimolar): 1.302736
 - cajsr in component intracellular_ions (millimolar): 1.264479
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003702
 - hf in component INa (dimensionless): 0.876014
 - hs in component INa (dimensionless): 0.876009
 - j in component INa (dimensionless): 0.875977
 - hsp in component INa (dimensionless): 0.718359
 - jp in component INa (dimensionless): 0.875955
 - mL in component INaL (dimensionless): 0.000052
 - hL in component INaL (dimensionless): 0.702229
 - hLp in component INaL (dimensionless): 0.440318
 - a in component Ito (dimensionless): 0.000633
 - iF in component Ito (dimensionless): 0.999864
 - iS in component Ito (dimensionless): 0.614271
 - ap in component Ito (dimensionless): 0.000322
 - iFp in component Ito (dimensionless): 0.999864
 - iSp in component Ito (dimensionless): 0.687472
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.933371
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999876
 - jca in component ICaL (dimensionless): 0.999976
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001567
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.344475
 - xs1 in component IKs (dimensionless): 0.246667
 - xs2 in component IKs (dimensionless): 0.000090
 - xk1 in component IK1 (dimensionless): 0.997396
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
08:42:44 (8332): called boinc_finish(0)

</stderr_txt>
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