𝕏

Task 55387902

Name HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_754_1
Workunit 26301004
Created 30 Jun 2024, 3:48:31 UTC
Sent 30 Jun 2024, 5:25:22 UTC
Report deadline 3 Jul 2024, 15:01:22 UTC
Received 3 Jul 2024, 1:09:57 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 213681
Run time 2 hours 55 min 44 sec
CPU time 2 hours 45 min
Validate state Valid
Credit 63.92
Device peak FLOPS 3.69 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.13 MB
Peak swap size 6.22 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>8.0.3</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_754.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_754_1_r144055508_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_754_1_r144055508_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 96.537639
     * GNaL_b in INaL: 0.005229
     * Gto_b in Ito: 0.094739
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.032407
     * GKs_b in IKs: 0.002086
     * GK1_b in IK1: 0.178983
     * Gncx_b in INaCa_i: 0.000956
     * Pnak_b in INaK: 67.474657
     * GKb_b in IKb: 0.003930
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.023707
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12140729, states[0] = -66.848426, states[40]= 0.000002
Saving checkpoint... 
Iteration: 23961181, states[0] = -95.113124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 36417236, states[0] = -95.092582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48605189, states[0] = -26.546213, states[40]= 0.000639
Saving checkpoint... 
Iteration: 61266102, states[0] = -94.998624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 73580855, states[0] = -4.484702, states[40]= 0.003487
Saving checkpoint... 
Iteration: 86312933, states[0] = -95.032303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 98983727, states[0] = -95.086072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 111215057, states[0] = -94.920312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 123884698, states[0] = -95.062950, states[40]= 0.000000
Saving checkpoint... 
Iteration: 135933445, states[0] = -95.075405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 148452092, states[0] = -95.078654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 160406101, states[0] = -95.068278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 173218744, states[0] = -94.924634, states[40]= 0.000000
Saving checkpoint... 
Iteration: 185453109, states[0] = -95.078292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 198507641, states[0] = 22.406697, states[40]= 0.093839
Saving checkpoint... 
Iteration: 210801128, states[0] = -95.019293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 223360156, states[0] = -95.052262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 235899783, states[0] = -95.065971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 249001949, states[0] = 42.952653, states[40]= 0.108781
Saving checkpoint... 
Iteration: 261811766, states[0] = -95.026590, states[40]= 0.000000
Saving checkpoint... 
Iteration: 274185318, states[0] = -94.858360, states[40]= 0.000000
Saving checkpoint... 
Iteration: 286797565, states[0] = -95.016446, states[40]= 0.000000
Saving checkpoint... 
Iteration: 299221608, states[0] = -94.928945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 311239046, states[0] = -94.955366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 322759385, states[0] = -94.980822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 334283581, states[0] = -95.004934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 346781864, states[0] = -95.003400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 359724649, states[0] = -94.933832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 372009428, states[0] = 21.601171, states[40]= 0.059745
Saving checkpoint... 
Iteration: 384019685, states[0] = 20.119921, states[40]= 0.008818
Saving checkpoint... 
Iteration: 395984359, states[0] = -95.082617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 408305899, states[0] = -95.022439, states[40]= 0.000000
Saving checkpoint... 
Iteration: 421169849, states[0] = -94.704470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 433504023, states[0] = 29.246103, states[40]= 0.180478
Saving checkpoint... 
Iteration: 446167204, states[0] = -94.520944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 459797109, states[0] = -95.015943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 474228113, states[0] = -94.939193, states[40]= 0.000000
Saving checkpoint... 
Iteration: 488696119, states[0] = -94.881541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 503212168, states[0] = -94.912479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 517674379, states[0] = -94.809464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 532494388, states[0] = -95.083761, states[40]= 0.000000
Saving checkpoint... 
Iteration: 546982338, states[0] = -95.082226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 561529333, states[0] = 17.933616, states[40]= 0.005585
Saving checkpoint... 
Iteration: 575959475, states[0] = -95.078796, states[40]= 0.000000
Saving checkpoint... 
Iteration: 590551812, states[0] = 10.188754, states[40]= 0.004759
Saving checkpoint... 
Iteration: 604905413, states[0] = -95.067184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 619020442, states[0] = 19.989364, states[40]= 0.008240
Saving checkpoint... 
Iteration: 632203805, states[0] = -94.896747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 644501989, states[0] = 42.619591, states[40]= 0.111533
Saving checkpoint... 
Iteration: 648005441, states[0] = 25.069450, states[40]= 0.153257
Saving checkpoint... 
Iteration: 659931023, states[0] = -95.073348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 671842359, states[0] = -95.043756, states[40]= 0.000000
Saving checkpoint... 
Iteration: 682895280, states[0] = -95.064229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 694782153, states[0] = -95.003373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 707594569, states[0] = -15.656890, states[40]= 0.001379
Saving checkpoint... 
Iteration: 719414748, states[0] = -95.069526, states[40]= 0.000000
Saving checkpoint... 
Iteration: 731216054, states[0] = -94.919172, states[40]= 0.000000
Saving checkpoint... 
Iteration: 742732795, states[0] = -94.946056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 754922357, states[0] = -95.071332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 766529860, states[0] = 17.785648, states[40]= 0.005525
Saving checkpoint... 
Iteration: 778393415, states[0] = -95.063589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 790807776, states[0] = -95.023434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 803039710, states[0] = 14.644203, states[40]= 0.004925
Saving checkpoint... 
Iteration: 813526459, states[0] = 18.694422, states[40]= 0.006010
Saving checkpoint... 
Iteration: 826010053, states[0] = 21.439054, states[40]= 0.051013
Saving checkpoint... 
Iteration: 837957016, states[0] = -95.078173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 850660732, states[0] = -92.311423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 863541852, states[0] = 13.890198, states[40]= 0.004869
Saving checkpoint... 
Iteration: 875634567, states[0] = -54.947534, states[40]= 0.000013
Saving checkpoint... 
Iteration: 887777730, states[0] = -94.999181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 899278825, states[0] = -95.000187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 911277279, states[0] = -94.998740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 922794607, states[0] = -95.013622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 934434771, states[0] = -95.073917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 947045846, states[0] = 12.443441, states[40]= 0.004803
Saving checkpoint... 
Iteration: 958637031, states[0] = -57.720768, states[40]= 0.000008
Saving checkpoint... 
Iteration: 971441334, states[0] = -95.075210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 983996624, states[0] = -95.083659, states[40]= 0.000000
Saving checkpoint... 
Iteration: 995982498, states[0] = -95.081883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1008183256, states[0] = -94.852654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1020618789, states[0] = -38.501758, states[40]= 0.000166
Saving checkpoint... 
Iteration: 1033419859, states[0] = -95.070518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1046204872, states[0] = -94.898463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1058152140, states[0] = -79.145054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1070779439, states[0] = -95.000612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1083129659, states[0] = -49.604438, states[40]= 0.000031
Saving checkpoint... 
Iteration: 1095375924, states[0] = -95.057553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1107467870, states[0] = -95.079701, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1120463990, states[0] = -95.079086, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1133117297, states[0] = -37.053781, states[40]= 0.000203
Saving checkpoint... 
Iteration: 1145695743, states[0] = -94.880231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1158616332, states[0] = -36.124283, states[40]= 0.000230
Saving checkpoint... 
Iteration: 1171283192, states[0] = -95.003906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1183822877, states[0] = -95.032789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1196476260, states[0] = -95.080863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1208579593, states[0] = -3.325068, states[40]= 0.003700
Saving checkpoint... 
Iteration: 1221130391, states[0] = -50.388558, states[40]= 0.000027
Saving checkpoint... 
Iteration: 1233416639, states[0] = -95.069577, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1246170021, states[0] = -94.711022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1258835676, states[0] = -95.039881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1270913469, states[0] = -95.068757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1283255817, states[0] = -94.975942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1295165431, states[0] = -94.270086, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1307372401, states[0] = -95.056098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1319818155, states[0] = -95.029806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1332486797, states[0] = -95.082173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1344618468, states[0] = -38.188798, states[40]= 0.000173
Saving checkpoint... 
Iteration: 1357129248, states[0] = -49.165723, states[40]= 0.000033
Saving checkpoint... 
Iteration: 1369638322, states[0] = -59.208568, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1382003773, states[0] = 30.346431, states[40]= 0.180576
Saving checkpoint... 
Iteration: 1394693112, states[0] = -94.874559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1407004318, states[0] = 28.113045, states[40]= 0.177900
Saving checkpoint... 
Iteration: 1419457087, states[0] = -95.077713, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1431825231, states[0] = -95.033971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1444172336, states[0] = -94.778323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1456874516, states[0] = -95.056752, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1469374672, states[0] = -95.056799, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1481658361, states[0] = -89.914391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1493875487, states[0] = -95.057073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1505904423, states[0] = -95.188821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1518306791, states[0] = 24.456666, states[40]= 0.106885
Saving checkpoint... 
Iteration: 1530667170, states[0] = -3.861041, states[40]= 0.004048
Saving checkpoint... 
Iteration: 1542867135, states[0] = -95.293534, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1555161282, states[0] = -95.293810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1567649828, states[0] = -95.062913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1579695958, states[0] = -95.212237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1592359883, states[0] = -95.300546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1604393657, states[0] = -95.327929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1616130773, states[0] = 15.923909, states[40]= 0.006429
Saving checkpoint... 
Iteration: 1628590070, states[0] = -95.204896, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1640901895, states[0] = -95.227662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1653376738, states[0] = -14.250330, states[40]= 0.001778
Saving checkpoint... 
Iteration: 1666388152, states[0] = -95.201707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1678964056, states[0] = -95.145024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1690891900, states[0] = -30.838489, states[40]= 0.000426
Saving checkpoint... 
Iteration: 1703602827, states[0] = -95.229872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1716209719, states[0] = -95.241531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1728781048, states[0] = -95.186670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1741689310, states[0] = -95.204293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1754301112, states[0] = -95.226854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1766137293, states[0] = 13.035213, states[40]= 0.005910
Saving checkpoint... 
Iteration: 1778861017, states[0] = -95.136624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1791292224, states[0] = -95.329129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1804065162, states[0] = 3.101759, states[40]= 0.004624
Saving checkpoint... 
Iteration: 1816330259, states[0] = -95.072910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1828524677, states[0] = 18.808038, states[40]= 0.006300
Saving checkpoint... 
Iteration: 1840777543, states[0] = -95.016955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1852481898, states[0] = -95.094222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1865079517, states[0] = -3.646796, states[40]= 0.003649
Saving checkpoint... 
Iteration: 1876025022, states[0] = 18.963245, states[40]= 0.006298
Saving checkpoint... 
Iteration: 1886923792, states[0] = -95.075443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1898575492, states[0] = -0.879284, states[40]= 0.004098
Saving checkpoint... 
Iteration: 1911257864, states[0] = -94.980098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1924059685, states[0] = 6.964484, states[40]= 0.004704
Saving checkpoint... 
Iteration: 1935805412, states[0] = -95.021922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1947342468, states[0] = -95.043509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1959875258, states[0] = -95.057097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1972426032, states[0] = -95.071496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1985242118, states[0] = -94.958383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1997751901, states[0] = -94.970803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2010588059, states[0] = -9.795962, states[40]= 0.002371
Saving checkpoint... 
Iteration: 2023256358, states[0] = -94.975979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2035810875, states[0] = -95.024508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2047994767, states[0] = -95.082541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2060423355, states[0] = -95.070454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2072400514, states[0] = -95.064570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2083960692, states[0] = -95.077709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2096603795, states[0] = -24.295726, states[40]= 0.000745
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.958948
 - CaMKt in component CaMK (millimolar): 0.007404
 - cass in component intracellular_ions (millimolar): 0.000075
 - nai in component intracellular_ions (millimolar): 6.689706
 - nass in component intracellular_ions (millimolar): 6.689767
 - ki in component intracellular_ions (millimolar): 145.279570
 - kss in component intracellular_ions (millimolar): 145.279550
 - cansr in component intracellular_ions (millimolar): 1.341669
 - cajsr in component intracellular_ions (millimolar): 1.303415
 - cai in component intracellular_ions (millimolar): 0.000076
 - m in component INa (dimensionless): 0.003598
 - hf in component INa (dimensionless): 0.880988
 - hs in component INa (dimensionless): 0.880983
 - j in component INa (dimensionless): 0.880956
 - hsp in component INa (dimensionless): 0.727694
 - jp in component INa (dimensionless): 0.880937
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.711866
 - hLp in component INaL (dimensionless): 0.455106
 - a in component Ito (dimensionless): 0.000621
 - iF in component Ito (dimensionless): 0.999871
 - iS in component Ito (dimensionless): 0.623254
 - ap in component Ito (dimensionless): 0.000316
 - iFp in component Ito (dimensionless): 0.999871
 - iSp in component Ito (dimensionless): 0.699183
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.938702
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999895
 - jca in component ICaL (dimensionless): 0.999979
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001712
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.312879
 - xs1 in component IKs (dimensionless): 0.237022
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997322
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
18:09:25 (14820): called boinc_finish(0)

</stderr_txt>
]]>


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