𝕏

Task 55387901

Name HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_754_0
Workunit 26301004
Created 30 Jun 2024, 3:48:31 UTC
Sent 30 Jun 2024, 5:27:07 UTC
Report deadline 3 Jul 2024, 15:03:07 UTC
Received 30 Jun 2024, 7:43:02 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 230332
Run time 2 hours 15 min 38 sec
CPU time 2 hours 13 min 33 sec
Validate state Initial
Credit 0.00
Device peak FLOPS 3.58 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 5.83 MB
Peak swap size 1.43 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_754.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_754_0_r408867899_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_754_0_r408867899_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 96.537639
     * GNaL_b in INaL: 0.005229
     * Gto_b in Ito: 0.094739
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.032407
     * GKs_b in IKs: 0.002086
     * GK1_b in IK1: 0.178983
     * Gncx_b in INaCa_i: 0.000956
     * Pnak_b in INaK: 67.474657
     * GKb_b in IKb: 0.003930
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.023707
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 17219664, states[0] = -94.975548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 34333142, states[0] = -95.063235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 51579495, states[0] = -3.807466, states[40]= 0.003621
Saving checkpoint... 
Iteration: 68813382, states[0] = -95.035898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 86061475, states[0] = 6.115605, states[40]= 0.004680
Saving checkpoint... 
Iteration: 103258409, states[0] = -94.982858, states[40]= 0.000000
Saving checkpoint... 
Iteration: 120377909, states[0] = -95.060814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 137598397, states[0] = -19.307609, states[40]= 0.001019
Saving checkpoint... 
Iteration: 154830734, states[0] = -95.038768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 172108585, states[0] = -28.809843, states[40]= 0.000534
Saving checkpoint... 
Iteration: 189291524, states[0] = -95.011994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 206453028, states[0] = -95.078140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 223672514, states[0] = -94.783008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 240966391, states[0] = -95.080228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 258159460, states[0] = -91.185677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 275442802, states[0] = -95.076079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 292676635, states[0] = -94.828302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 309905451, states[0] = -95.067441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 327141660, states[0] = -63.223557, states[40]= 0.000003
Saving checkpoint... 
Iteration: 344295416, states[0] = -95.014730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 361590206, states[0] = -11.667516, states[40]= 0.002004
Saving checkpoint... 
Iteration: 378812448, states[0] = -95.026918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 396049580, states[0] = 11.045990, states[40]= 0.004771
Saving checkpoint... 
Iteration: 413186568, states[0] = -94.861131, states[40]= 0.000000
Saving checkpoint... 
Iteration: 430403732, states[0] = -95.066865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 447636562, states[0] = -57.187290, states[40]= 0.000009
Saving checkpoint... 
Iteration: 464842808, states[0] = -95.044144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 482045303, states[0] = 12.642882, states[40]= 0.004810
Saving checkpoint... 
Iteration: 499267360, states[0] = -94.989293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 516430603, states[0] = -95.073374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 533629079, states[0] = -48.986553, states[40]= 0.000034
Saving checkpoint... 
Iteration: 550848559, states[0] = -95.046817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 568012743, states[0] = 21.019235, states[40]= 0.026774
Saving checkpoint... 
Iteration: 585230380, states[0] = -94.942573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 602383624, states[0] = -95.060614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 619632790, states[0] = -52.989411, states[40]= 0.000018
Saving checkpoint... 
Iteration: 636883993, states[0] = -95.060709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 654135806, states[0] = -56.332688, states[40]= 0.000010
Saving checkpoint... 
Iteration: 671389204, states[0] = -95.062370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 688660155, states[0] = -91.841703, states[40]= 0.000000
Saving checkpoint... 
Iteration: 705904375, states[0] = -95.066818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 723105890, states[0] = -26.256749, states[40]= 0.000655
Saving checkpoint... 
Iteration: 740369832, states[0] = -95.055596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 757625760, states[0] = -45.501592, states[40]= 0.000059
Saving checkpoint... 
Iteration: 774872051, states[0] = -95.056401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 792053285, states[0] = 9.613092, states[40]= 0.004751
Saving checkpoint... 
Iteration: 809252228, states[0] = -94.972059, states[40]= 0.000000
Saving checkpoint... 
Iteration: 826517069, states[0] = 20.513408, states[40]= 0.012018
Saving checkpoint... 
Iteration: 843755308, states[0] = -94.975704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 860992157, states[0] = -95.083226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 878181257, states[0] = -94.847215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 895427270, states[0] = -95.072336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 912675595, states[0] = -94.820472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 929908475, states[0] = -95.067742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 947157645, states[0] = -88.943517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 964247114, states[0] = -94.965569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 981449070, states[0] = -95.076661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 998713465, states[0] = -94.914397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1015928160, states[0] = -95.072436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1033144236, states[0] = -66.558065, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1050327075, states[0] = -95.035343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1067539460, states[0] = 14.731026, states[40]= 0.004932
Saving checkpoint... 
Iteration: 1084809384, states[0] = -95.024294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1102066108, states[0] = 4.139364, states[40]= 0.004587
Saving checkpoint... 
Iteration: 1119300167, states[0] = -95.017716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1136529771, states[0] = 17.810913, states[40]= 0.005535
Saving checkpoint... 
Iteration: 1153808000, states[0] = -95.023293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1171091183, states[0] = -12.543859, states[40]= 0.001846
Saving checkpoint... 
Iteration: 1188257281, states[0] = -94.977716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1205464363, states[0] = -95.079076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1222683335, states[0] = -94.852682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1239860635, states[0] = -95.051548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1257104682, states[0] = -25.125626, states[40]= 0.000707
Saving checkpoint... 
Iteration: 1274300480, states[0] = -95.017822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1291523579, states[0] = 19.368958, states[40]= 0.006725
Saving checkpoint... 
Iteration: 1308655924, states[0] = -86.185321, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1325902825, states[0] = -95.065886, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1343065857, states[0] = 4.257179, states[40]= 0.004594
Saving checkpoint... 
Iteration: 1360252771, states[0] = -94.972265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1377509457, states[0] = 21.592884, states[40]= 0.059307
Saving checkpoint... 
Iteration: 1394831086, states[0] = -95.037307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1412040055, states[0] = 14.524177, states[40]= 0.004914
Saving checkpoint... 
Iteration: 1429247670, states[0] = -94.965898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1446492296, states[0] = -95.082768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1463763687, states[0] = -94.984624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1481059235, states[0] = 7.192191, states[40]= 0.004709
Saving checkpoint... 
Iteration: 1498286153, states[0] = -95.006214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1515289993, states[0] = -95.289922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1532405359, states[0] = 26.646412, states[40]= 0.138948
Saving checkpoint... 
Iteration: 1549511554, states[0] = 21.838838, states[40]= 0.036627
Saving checkpoint... 
Iteration: 1566682926, states[0] = -20.592390, states[40]= 0.000999
Saving checkpoint... 
Iteration: 1583785098, states[0] = -23.161427, states[40]= 0.000819
Saving checkpoint... 
Iteration: 1600957631, states[0] = -95.123455, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1618124028, states[0] = -95.261646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1635210271, states[0] = -95.241701, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1652375107, states[0] = -95.316485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1669459625, states[0] = -95.303417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1686624236, states[0] = 18.376599, states[40]= 0.007653
Saving checkpoint... 
Iteration: 1703806830, states[0] = -47.693600, states[40]= 0.000044
Saving checkpoint... 
Iteration: 1720922589, states[0] = -68.338576, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1737921483, states[0] = 19.263076, states[40]= 0.008830
Saving checkpoint... 
Iteration: 1755063480, states[0] = -1.866736, states[40]= 0.004456
Saving checkpoint... 
Iteration: 1772221562, states[0] = -66.780891, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1789282471, states[0] = -20.545226, states[40]= 0.001003
Saving checkpoint... 
Iteration: 1806433269, states[0] = -95.118622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1823598288, states[0] = -21.121385, states[40]= 0.000906
Saving checkpoint... 
Iteration: 1840791640, states[0] = -95.029183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1857947509, states[0] = -95.086812, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1875090853, states[0] = -12.642621, states[40]= 0.001832
Saving checkpoint... 
Iteration: 1892091200, states[0] = -12.800752, states[40]= 0.001804
Saving checkpoint... 
Iteration: 1909257214, states[0] = -94.979498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1926483590, states[0] = -95.082690, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1943601794, states[0] = -22.480921, states[40]= 0.000830
Saving checkpoint... 
Iteration: 1960660276, states[0] = -91.982335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1977813286, states[0] = -95.026423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1994863796, states[0] = -95.052346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2011996299, states[0] = -95.082831, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2029137569, states[0] = -58.342953, states[40]= 0.000007
Saving checkpoint... 
Iteration: 2046296339, states[0] = -95.014024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2063445486, states[0] = -95.075068, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2080577084, states[0] = -1.717453, states[40]= 0.003971
Saving checkpoint... 
Iteration: 2097733440, states[0] = -94.945830, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.958948
 - CaMKt in component CaMK (millimolar): 0.007404
 - cass in component intracellular_ions (millimolar): 0.000075
 - nai in component intracellular_ions (millimolar): 6.689706
 - nass in component intracellular_ions (millimolar): 6.689767
 - ki in component intracellular_ions (millimolar): 145.279570
 - kss in component intracellular_ions (millimolar): 145.279550
 - cansr in component intracellular_ions (millimolar): 1.341669
 - cajsr in component intracellular_ions (millimolar): 1.303415
 - cai in component intracellular_ions (millimolar): 0.000076
 - m in component INa (dimensionless): 0.003598
 - hf in component INa (dimensionless): 0.880988
 - hs in component INa (dimensionless): 0.880983
 - j in component INa (dimensionless): 0.880956
 - hsp in component INa (dimensionless): 0.727694
 - jp in component INa (dimensionless): 0.880937
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.711866
 - hLp in component INaL (dimensionless): 0.455106
 - a in component Ito (dimensionless): 0.000621
 - iF in component Ito (dimensionless): 0.999871
 - iS in component Ito (dimensionless): 0.623254
 - ap in component Ito (dimensionless): 0.000316
 - iFp in component Ito (dimensionless): 0.999871
 - iSp in component Ito (dimensionless): 0.699183
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.938702
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999895
 - jca in component ICaL (dimensionless): 0.999979
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001712
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.312879
 - xs1 in component IKs (dimensionless): 0.237022
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997322
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
08:42:49 (16316): called boinc_finish(0)

</stderr_txt>
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