𝕏

Task 55387877

Name HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_53_0
Workunit 26300992
Created 30 Jun 2024, 3:48:31 UTC
Sent 30 Jun 2024, 5:25:22 UTC
Report deadline 3 Jul 2024, 15:01:22 UTC
Received 2 Jul 2024, 7:33:44 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 213681
Run time 2 hours 43 min 53 sec
CPU time 2 hours 37 min 45 sec
Validate state Initial
Credit 0.00
Device peak FLOPS 3.69 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.41 MB
Peak swap size 6.20 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>8.0.3</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_53.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_53_0_r848179491_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_53_0_r848179491_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 114.034541
     * GNaL_b in INaL: 0.005954
     * Gto_b in Ito: 0.074521
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033672
     * GKs_b in IKs: 0.002122
     * GK1_b in IK1: 0.170026
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 72.748732
     * GKb_b in IKb: 0.003908
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.028727
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 16224261, states[0] = -95.004895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 32020302, states[0] = 20.945737, states[40]= 0.010438
Saving checkpoint... 
Iteration: 48509796, states[0] = 24.344024, states[40]= 0.056620
Saving checkpoint... 
Iteration: 64895522, states[0] = -95.059807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 81291741, states[0] = -95.004103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 97740970, states[0] = -94.950004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 114106019, states[0] = -31.567420, states[40]= 0.000370
Saving checkpoint... 
Iteration: 130506429, states[0] = 27.608002, states[40]= 0.112886
Saving checkpoint... 
Iteration: 146944499, states[0] = -95.056174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 161757956, states[0] = -94.964642, states[40]= 0.000000
Saving checkpoint... 
Iteration: 173548980, states[0] = 10.861268, states[40]= 0.005249
Saving checkpoint... 
Iteration: 186165899, states[0] = -94.759252, states[40]= 0.000000
Saving checkpoint... 
Iteration: 199027017, states[0] = 19.386806, states[40]= 0.007303
Saving checkpoint... 
Iteration: 211582589, states[0] = -8.252816, states[40]= 0.002788
Saving checkpoint... 
Iteration: 223602229, states[0] = -27.508158, states[40]= 0.000554
Saving checkpoint... 
Iteration: 236032849, states[0] = 17.365276, states[40]= 0.006266
Saving checkpoint... 
Iteration: 248383377, states[0] = -95.040214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 260192361, states[0] = -94.865391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 272599746, states[0] = -24.999352, states[40]= 0.000675
Saving checkpoint... 
Iteration: 285215363, states[0] = -94.906856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 298191231, states[0] = -94.863110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 311523618, states[0] = 20.450883, states[40]= 0.008450
Saving checkpoint... 
Iteration: 323870572, states[0] = -95.035849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 335761917, states[0] = -94.967819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 348394738, states[0] = -95.043479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 360156745, states[0] = -93.753005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 372789151, states[0] = -94.992188, states[40]= 0.000000
Saving checkpoint... 
Iteration: 385323625, states[0] = -95.014894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 396948445, states[0] = -95.055383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 409398893, states[0] = -95.044594, states[40]= 0.000000
Saving checkpoint... 
Iteration: 422239146, states[0] = -94.941477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 434909179, states[0] = -95.047242, states[40]= 0.000000
Saving checkpoint... 
Iteration: 446695586, states[0] = -94.871513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 459330317, states[0] = -95.018440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 471542575, states[0] = 13.561803, states[40]= 0.005489
Saving checkpoint... 
Iteration: 484136939, states[0] = -66.456745, states[40]= 0.000002
Saving checkpoint... 
Iteration: 496862795, states[0] = -95.032897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 508351059, states[0] = -95.028169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 520968704, states[0] = -95.058480, states[40]= 0.000000
Saving checkpoint... 
Iteration: 533961969, states[0] = -95.057487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 545955821, states[0] = -95.056525, states[40]= 0.000000
Saving checkpoint... 
Iteration: 557588111, states[0] = -13.352971, states[40]= 0.001766
Saving checkpoint... 
Iteration: 569878285, states[0] = -95.038342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 582176931, states[0] = -94.832442, states[40]= 0.000000
Saving checkpoint... 
Iteration: 594803657, states[0] = -95.002575, states[40]= 0.000000
Saving checkpoint... 
Iteration: 607444890, states[0] = -95.054651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 619465640, states[0] = -95.057987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 631652027, states[0] = -90.638973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 643622535, states[0] = -48.906663, states[40]= 0.000031
Saving checkpoint... 
Iteration: 655684812, states[0] = -94.849924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 667472927, states[0] = -95.058990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 679661858, states[0] = -94.602853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 691541373, states[0] = 14.053326, states[40]= 0.005551
Saving checkpoint... 
Iteration: 704429746, states[0] = -95.051718, states[40]= 0.000000
Saving checkpoint... 
Iteration: 716630380, states[0] = -58.089998, states[40]= 0.000007
Saving checkpoint... 
Iteration: 728187092, states[0] = -94.854562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 740636241, states[0] = -65.508536, states[40]= 0.000002
Saving checkpoint... 
Iteration: 753150721, states[0] = -89.036303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 765723833, states[0] = -94.919876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 778417761, states[0] = -95.049094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 790733793, states[0] = -94.934163, states[40]= 0.000000
Saving checkpoint... 
Iteration: 803125381, states[0] = -52.179529, states[40]= 0.000018
Saving checkpoint... 
Iteration: 815477042, states[0] = -95.059461, states[40]= 0.000000
Saving checkpoint... 
Iteration: 828086545, states[0] = -11.846691, states[40]= 0.002038
Saving checkpoint... 
Iteration: 839659185, states[0] = -94.319966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 852602382, states[0] = -27.653327, states[40]= 0.000547
Saving checkpoint... 
Iteration: 865442568, states[0] = -95.054098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 877772535, states[0] = -94.977844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 889421744, states[0] = -95.049926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 901868267, states[0] = -95.034711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 914484818, states[0] = -95.060392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 926804716, states[0] = -95.003108, states[40]= 0.000000
Saving checkpoint... 
Iteration: 939220854, states[0] = -94.915228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 950816257, states[0] = -95.010363, states[40]= 0.000000
Saving checkpoint... 
Iteration: 963449878, states[0] = -95.055325, states[40]= 0.000000
Saving checkpoint... 
Iteration: 975983896, states[0] = -95.060246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 989183862, states[0] = -94.847769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1001157952, states[0] = -94.085261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1013400439, states[0] = -95.044688, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1025780546, states[0] = -94.984845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1038110246, states[0] = -35.640421, states[40]= 0.000223
Saving checkpoint... 
Iteration: 1050559008, states[0] = 6.380435, states[40]= 0.004988
Saving checkpoint... 
Iteration: 1063881402, states[0] = -95.039090, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1077398607, states[0] = -95.044160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1090905655, states[0] = -95.046009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1104603802, states[0] = -29.086569, states[40]= 0.000480
Saving checkpoint... 
Iteration: 1118190964, states[0] = -94.862126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1131900000, states[0] = -95.044508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1145475503, states[0] = -95.059083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1159117720, states[0] = -43.532603, states[40]= 0.000072
Saving checkpoint... 
Iteration: 1173223662, states[0] = -94.919400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1187747016, states[0] = -94.950853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1201681077, states[0] = -94.841725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1216221261, states[0] = -94.915709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1230748646, states[0] = -94.952761, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1245284332, states[0] = -94.987880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1259373784, states[0] = -95.036463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1273869362, states[0] = -95.034906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1288386679, states[0] = -95.040615, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1302984806, states[0] = -95.060184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1317535384, states[0] = 16.418757, states[40]= 0.005989
Saving checkpoint... 
Iteration: 1332819661, states[0] = -95.012151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1348158660, states[0] = -94.230484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1363274615, states[0] = -94.979479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1378449046, states[0] = -95.054963, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1393163638, states[0] = -94.694463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1408430651, states[0] = -95.051528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1423742983, states[0] = -94.945810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1439003357, states[0] = 37.443630, states[40]= 0.124973
Saving checkpoint... 
Iteration: 1454371436, states[0] = -95.035545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1469546110, states[0] = 12.092366, states[40]= 0.005342
Saving checkpoint... 
Iteration: 1484790993, states[0] = -94.993014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1500180403, states[0] = -95.094651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1515452615, states[0] = -95.078914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1530678917, states[0] = -17.965243, states[40]= 0.001260
Saving checkpoint... 
Iteration: 1545545874, states[0] = -95.272919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1560595126, states[0] = -95.318282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1575888091, states[0] = -95.317709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1591119980, states[0] = -95.254746, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1605663153, states[0] = -2.872896, states[40]= 0.004368
Saving checkpoint... 
Iteration: 1620855907, states[0] = -95.297287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1636156565, states[0] = -95.298410, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1651421591, states[0] = -95.259996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1666799306, states[0] = -95.330160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1682043487, states[0] = -95.286229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1697315611, states[0] = -95.252104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1712664340, states[0] = -95.305885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1727780572, states[0] = -21.280455, states[40]= 0.000942
Saving checkpoint... 
Iteration: 1742804719, states[0] = -49.903501, states[40]= 0.000028
Saving checkpoint... 
Iteration: 1757899863, states[0] = -95.227662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1773991882, states[0] = -34.335022, states[40]= 0.000266
Saving checkpoint... 
Iteration: 1790010592, states[0] = -95.244793, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1806096384, states[0] = -25.142613, states[40]= 0.000687
Saving checkpoint... 
Iteration: 1821567750, states[0] = 0.949833, states[40]= 0.004558
Saving checkpoint... 
Iteration: 1837778648, states[0] = -95.004127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1853866995, states[0] = -95.046795, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1869972599, states[0] = -95.066308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1886010221, states[0] = 24.288359, states[40]= 0.051581
Saving checkpoint... 
Iteration: 1902129390, states[0] = -57.161698, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1918257406, states[0] = -94.964114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1934291719, states[0] = -94.994466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1949955819, states[0] = -95.056469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1965245623, states[0] = -94.949194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1980455776, states[0] = -95.056008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1995686797, states[0] = -94.853431, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2010930194, states[0] = -95.051192, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2025706431, states[0] = -94.890740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2040889367, states[0] = -95.041029, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2056136719, states[0] = -66.157273, states[40]= 0.000002
Saving checkpoint... 
Iteration: 2071414919, states[0] = -95.047729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2086640369, states[0] = -71.433755, states[40]= 0.000001
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.937326
 - CaMKt in component CaMK (millimolar): 0.006572
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.537721
 - nass in component intracellular_ions (millimolar): 6.537781
 - ki in component intracellular_ions (millimolar): 145.444299
 - kss in component intracellular_ions (millimolar): 145.444280
 - cansr in component intracellular_ions (millimolar): 1.296341
 - cajsr in component intracellular_ions (millimolar): 1.259539
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003606
 - hf in component INa (dimensionless): 0.880615
 - hs in component INa (dimensionless): 0.880611
 - j in component INa (dimensionless): 0.880585
 - hsp in component INa (dimensionless): 0.726991
 - jp in component INa (dimensionless): 0.880567
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.712910
 - hLp in component INaL (dimensionless): 0.459420
 - a in component Ito (dimensionless): 0.000622
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.629880
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.706302
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.938978
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999899
 - jca in component ICaL (dimensionless): 0.999981
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001558
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.332160
 - xs1 in component IKs (dimensionless): 0.229914
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997328
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
00:12:41 (19136): called boinc_finish(0)

</stderr_txt>
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