𝕏

Task 55387741

Name HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_841_0
Workunit 26300924
Created 30 Jun 2024, 3:48:26 UTC
Sent 30 Jun 2024, 5:28:51 UTC
Report deadline 3 Jul 2024, 15:04:51 UTC
Received 30 Jun 2024, 23:07:13 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 240173
Run time 1 hours 36 min 2 sec
CPU time 1 hours 17 min 52 sec
Validate state Valid
Credit 60.48
Device peak FLOPS 1.00 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.37 MB
Peak swap size 6.45 MB
Peak disk usage 0.33 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>
-----------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_841.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_841_0_r647235538_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_841_0_r647235538_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 110.992410
     * GNaL_b in INaL: 0.006092
     * Gto_b in Ito: 0.082576
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.030135
     * GKs_b in IKs: 0.001875
     * GK1_b in IK1: 0.147675
     * Gncx_b in INaCa_i: 0.000971
     * Pnak_b in INaK: 73.941364
     * GKb_b in IKb: 0.003670
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.054390
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 23609234
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -29.149953 (After loading)
 - states[40]: 0.000488 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 37193073, states[0] = -94.848108, states[40]= 0.000000
Saving checkpoint... 
Iteration: 50986013, states[0] = -95.045417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 65560913, states[0] = 7.805496, states[40]= 0.004827
Saving checkpoint... 
Iteration: 80589253, states[0] = -7.442550, states[40]= 0.002820
Saving checkpoint... 
Iteration: 95088795, states[0] = -6.871000, states[40]= 0.002937
Saving checkpoint... 
Iteration: 110675318, states[0] = -94.202003, states[40]= 0.000000
Saving checkpoint... 
Iteration: 125458472, states[0] = -95.006274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 139919984, states[0] = -94.996766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 153979455, states[0] = -95.007147, states[40]= 0.000000
Saving checkpoint... 
Iteration: 169528214, states[0] = 19.829050, states[40]= 0.006693
Saving checkpoint... 
Iteration: 183211878, states[0] = -94.825408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 198021695, states[0] = 21.451647, states[40]= 0.009136
Saving checkpoint... 
Iteration: 211201391, states[0] = -94.804425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 224694451, states[0] = -94.788133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 239721836, states[0] = -94.842701, states[40]= 0.000000
Saving checkpoint... 
Iteration: 251609772, states[0] = -24.977436, states[40]= 0.000701
Saving checkpoint... 
Iteration: 259055553, states[0] = 10.367396, states[40]= 0.004908
Saving checkpoint... 
Iteration: 268530519, states[0] = 19.178726, states[40]= 0.006274


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_841.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_841_0_r647235538_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_841_0_r647235538_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 110.992410
     * GNaL_b in INaL: 0.006092
     * Gto_b in Ito: 0.082576
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.030135
     * GKs_b in IKs: 0.001875
     * GK1_b in IK1: 0.147675
     * Gncx_b in INaCa_i: 0.000971
     * Pnak_b in INaK: 73.941364
     * GKb_b in IKb: 0.003670
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.054390
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 268530519
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: 19.178726 (After loading)
 - states[40]: 0.006274 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_841.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_841_0_r647235538_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_841_0_r647235538_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 110.992410
     * GNaL_b in INaL: 0.006092
     * Gto_b in Ito: 0.082576
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.030135
     * GKs_b in IKs: 0.001875
     * GK1_b in IK1: 0.147675
     * Gncx_b in INaCa_i: 0.000971
     * Pnak_b in INaK: 73.941364
     * GKb_b in IKb: 0.003670
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.054390
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 268530519
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: 19.178726 (After loading)
 - states[40]: 0.006274 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_841.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_841_0_r647235538_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_841_0_r647235538_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 110.992410
     * GNaL_b in INaL: 0.006092
     * Gto_b in Ito: 0.082576
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.030135
     * GKs_b in IKs: 0.001875
     * GK1_b in IK1: 0.147675
     * Gncx_b in INaCa_i: 0.000971
     * Pnak_b in INaK: 73.941364
     * GKb_b in IKb: 0.003670
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.054390
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 268530519
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: 19.178726 (After loading)
 - states[40]: 0.006274 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_841.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_841_0_r647235538_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_841_0_r647235538_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 110.992410
     * GNaL_b in INaL: 0.006092
     * Gto_b in Ito: 0.082576
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.030135
     * GKs_b in IKs: 0.001875
     * GK1_b in IK1: 0.147675
     * Gncx_b in INaCa_i: 0.000971
     * Pnak_b in INaK: 73.941364
     * GKb_b in IKb: 0.003670
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.054390
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 268530519
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: 19.178726 (After loading)
 - states[40]: 0.006274 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_841.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_841_0_r647235538_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_841_0_r647235538_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 110.992410
     * GNaL_b in INaL: 0.006092
     * Gto_b in Ito: 0.082576
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.030135
     * GKs_b in IKs: 0.001875
     * GK1_b in IK1: 0.147675
     * Gncx_b in INaCa_i: 0.000971
     * Pnak_b in INaK: 73.941364
     * GKb_b in IKb: 0.003670
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.054390
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 268530519
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: 19.178726 (After loading)
 - states[40]: 0.006274 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 284237193, states[0] = -94.867487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 299368219, states[0] = -94.977305, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_841.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_841_0_r647235538_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_841_0_r647235538_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 110.992410
     * GNaL_b in INaL: 0.006092
     * Gto_b in Ito: 0.082576
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.030135
     * GKs_b in IKs: 0.001875
     * GK1_b in IK1: 0.147675
     * Gncx_b in INaCa_i: 0.000971
     * Pnak_b in INaK: 73.941364
     * GKb_b in IKb: 0.003670
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.054390
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 299368219
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.977305 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 314800356, states[0] = -94.938049, states[40]= 0.000000
Saving checkpoint... 
Iteration: 328975300, states[0] = -95.004637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 340137796, states[0] = -52.204591, states[40]= 0.000018
Saving checkpoint... 
Iteration: 354113050, states[0] = -27.997054, states[40]= 0.000558
Saving checkpoint... 
Iteration: 369573160, states[0] = 2.857509, states[40]= 0.004485
Saving checkpoint... 
Iteration: 383894399, states[0] = -94.986668, states[40]= 0.000000
Saving checkpoint... 
Iteration: 399135808, states[0] = -50.119848, states[40]= 0.000026
Saving checkpoint... 
Iteration: 412980030, states[0] = -95.005265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 417706060, states[0] = -94.813359, states[40]= 0.000000
Saving checkpoint... 
Iteration: 427499042, states[0] = -95.007704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 439911094, states[0] = -94.991535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 451408663, states[0] = -94.990863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 462892097, states[0] = -94.985888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 474462173, states[0] = -95.002490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 486100298, states[0] = -16.254719, states[40]= 0.001277
Saving checkpoint... 
Iteration: 498084333, states[0] = -3.360239, states[40]= 0.003633
Saving checkpoint... 
Iteration: 510125569, states[0] = -39.777870, states[40]= 0.000128
Saving checkpoint... 
Iteration: 515181894, states[0] = -94.665961, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_841.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_841_0_r647235538_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_841_0_r647235538_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 110.992410
     * GNaL_b in INaL: 0.006092
     * Gto_b in Ito: 0.082576
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.030135
     * GKs_b in IKs: 0.001875
     * GK1_b in IK1: 0.147675
     * Gncx_b in INaCa_i: 0.000971
     * Pnak_b in INaK: 73.941364
     * GKb_b in IKb: 0.003670
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.054390
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 515181894
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.665961 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_841.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_841_0_r647235538_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_841_0_r647235538_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 110.992410
     * GNaL_b in INaL: 0.006092
     * Gto_b in Ito: 0.082576
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.030135
     * GKs_b in IKs: 0.001875
     * GK1_b in IK1: 0.147675
     * Gncx_b in INaCa_i: 0.000971
     * Pnak_b in INaK: 73.941364
     * GKb_b in IKb: 0.003670
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.054390
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 515181894
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.665961 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_841.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_841_0_r647235538_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_841_0_r647235538_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 110.992410
     * GNaL_b in INaL: 0.006092
     * Gto_b in Ito: 0.082576
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.030135
     * GKs_b in IKs: 0.001875
     * GK1_b in IK1: 0.147675
     * Gncx_b in INaCa_i: 0.000971
     * Pnak_b in INaK: 73.941364
     * GKb_b in IKb: 0.003670
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.054390
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 515181894
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.665961 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_841.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_841_0_r647235538_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_841_0_r647235538_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 110.992410
     * GNaL_b in INaL: 0.006092
     * Gto_b in Ito: 0.082576
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.030135
     * GKs_b in IKs: 0.001875
     * GK1_b in IK1: 0.147675
     * Gncx_b in INaCa_i: 0.000971
     * Pnak_b in INaK: 73.941364
     * GKb_b in IKb: 0.003670
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.054390
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 515181894
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.665961 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_841.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_841_0_r647235538_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_841_0_r647235538_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 110.992410
     * GNaL_b in INaL: 0.006092
     * Gto_b in Ito: 0.082576
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.030135
     * GKs_b in IKs: 0.001875
     * GK1_b in IK1: 0.147675
     * Gncx_b in INaCa_i: 0.000971
     * Pnak_b in INaK: 73.941364
     * GKb_b in IKb: 0.003670
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.054390
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 515181894
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.665961 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_841.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_841_0_r647235538_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_841_0_r647235538_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 110.992410
     * GNaL_b in INaL: 0.006092
     * Gto_b in Ito: 0.082576
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.030135
     * GKs_b in IKs: 0.001875
     * GK1_b in IK1: 0.147675
     * Gncx_b in INaCa_i: 0.000971
     * Pnak_b in INaK: 73.941364
     * GKb_b in IKb: 0.003670
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.054390
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 515181894
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.665961 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_841.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_841_0_r647235538_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_841_0_r647235538_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 110.992410
     * GNaL_b in INaL: 0.006092
     * Gto_b in Ito: 0.082576
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.030135
     * GKs_b in IKs: 0.001875
     * GK1_b in IK1: 0.147675
     * Gncx_b in INaCa_i: 0.000971
     * Pnak_b in INaK: 73.941364
     * GKb_b in IKb: 0.003670
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.054390
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 515181894
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.665961 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_841.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_841_0_r647235538_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_841_0_r647235538_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 110.992410
     * GNaL_b in INaL: 0.006092
     * Gto_b in Ito: 0.082576
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.030135
     * GKs_b in IKs: 0.001875
     * GK1_b in IK1: 0.147675
     * Gncx_b in INaCa_i: 0.000971
     * Pnak_b in INaK: 73.941364
     * GKb_b in IKb: 0.003670
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.054390
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 515181894
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.665961 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_841.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_841_0_r647235538_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_841_0_r647235538_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 110.992410
     * GNaL_b in INaL: 0.006092
     * Gto_b in Ito: 0.082576
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.030135
     * GKs_b in IKs: 0.001875
     * GK1_b in IK1: 0.147675
     * Gncx_b in INaCa_i: 0.000971
     * Pnak_b in INaK: 73.941364
     * GKb_b in IKb: 0.003670
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.054390
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 515181894
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.665961 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 527671569, states[0] = -92.995075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 540953845, states[0] = -95.001007, states[40]= 0.000000
Saving checkpoint... 
Iteration: 553963426, states[0] = -95.002657, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_841.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_841_0_r647235538_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_841_0_r647235538_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 110.992410
     * GNaL_b in INaL: 0.006092
     * Gto_b in Ito: 0.082576
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.030135
     * GKs_b in IKs: 0.001875
     * GK1_b in IK1: 0.147675
     * Gncx_b in INaCa_i: 0.000971
     * Pnak_b in INaK: 73.941364
     * GKb_b in IKb: 0.003670
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.054390
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 553963426
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -95.002657 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 555514854, states[0] = 22.733622, states[40]= 0.020281
Saving checkpoint... 
Iteration: 573265281, states[0] = -94.904331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 594455119, states[0] = -95.001209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 614866664, states[0] = -94.976478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 635278297, states[0] = -94.918183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 656229421, states[0] = -94.855072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 675195335, states[0] = -94.790039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 678076586, states[0] = 1.134694, states[40]= 0.004307
Saving checkpoint... 
Iteration: 682090024, states[0] = -7.405296, states[40]= 0.002816
Saving checkpoint... 
Iteration: 686134168, states[0] = -48.414178, states[40]= 0.000034
Saving checkpoint... 
Iteration: 690678575, states[0] = -94.503840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 695156900, states[0] = -74.602445, states[40]= 0.000000
Saving checkpoint... 
Iteration: 699624976, states[0] = -39.203515, states[40]= 0.000140
Saving checkpoint... 
Iteration: 703146694, states[0] = -61.799468, states[40]= 0.000003
Saving checkpoint... 
Iteration: 707543942, states[0] = 14.703792, states[40]= 0.005167
Saving checkpoint... 
Iteration: 711966630, states[0] = -95.003096, states[40]= 0.000000
Saving checkpoint... 
Iteration: 715954738, states[0] = -95.001078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 720051039, states[0] = 12.089335, states[40]= 0.004981
Saving checkpoint... 
Iteration: 724471883, states[0] = -95.003910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 728936063, states[0] = -94.997409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 732394874, states[0] = -94.986637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 735080173, states[0] = -0.825560, states[40]= 0.004052
Saving checkpoint... 
Iteration: 741096812, states[0] = -13.100788, states[40]= 0.001711
Saving checkpoint... 
Iteration: 759995997, states[0] = -95.007170, states[40]= 0.000000
Saving checkpoint... 
Iteration: 779066299, states[0] = 5.992523, states[40]= 0.004714
Saving checkpoint... 
Iteration: 797701514, states[0] = -94.804027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 816558966, states[0] = 9.029434, states[40]= 0.004856
Saving checkpoint... 
Iteration: 835251006, states[0] = -94.886679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 853943242, states[0] = -94.998830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 872996564, states[0] = -95.007180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 885085572, states[0] = -4.180088, states[40]= 0.003479
Saving checkpoint... 
Iteration: 896213629, states[0] = -94.827502, states[40]= 0.000000
Saving checkpoint... 
Iteration: 915003883, states[0] = 33.407504, states[40]= 0.131148
Saving checkpoint... 
Iteration: 934401962, states[0] = -94.988697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 953286491, states[0] = -94.925853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 972499522, states[0] = -95.007479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 991790581, states[0] = -94.929505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1000863405, states[0] = -94.974911, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1015606121, states[0] = -21.610587, states[40]= 0.000860
Saving checkpoint... 
Iteration: 1034982589, states[0] = -95.005300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1053812071, states[0] = -94.946442, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1061799875, states[0] = -94.937263, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1071932457, states[0] = -94.996448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1088498735, states[0] = -95.007327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1092611707, states[0] = -26.755667, states[40]= 0.000618
Saving checkpoint... 
Iteration: 1105273233, states[0] = -94.912758, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1109489277, states[0] = -95.006152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1122474041, states[0] = -95.004031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1141851357, states[0] = -94.969387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1160636884, states[0] = -51.245240, states[40]= 0.000021
Saving checkpoint... 
Iteration: 1179791324, states[0] = -94.930058, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1182144353, states[0] = -59.212321, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1185969539, states[0] = -95.003312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1189696042, states[0] = -94.791577, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1193792970, states[0] = -94.931475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1197755703, states[0] = -94.892539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1201457654, states[0] = -95.001344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1205626165, states[0] = -40.357259, states[40]= 0.000118
Saving checkpoint... 
Iteration: 1209648663, states[0] = -64.038324, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1213156983, states[0] = -74.722022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1217019890, states[0] = 21.829930, states[40]= 0.010577
Saving checkpoint... 
Iteration: 1221002276, states[0] = 43.827188, states[40]= 0.083073
Saving checkpoint... 
Iteration: 1223644355, states[0] = -59.214472, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1225281486, states[0] = -94.921006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1228078317, states[0] = 0.211422, states[40]= 0.004194
Saving checkpoint... 
Iteration: 1230947437, states[0] = -94.999458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1232947371, states[0] = -94.999444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1234982245, states[0] = -95.005150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1236005555, states[0] = 28.048349, states[40]= 0.126431
Saving checkpoint... 
Iteration: 1238888608, states[0] = -94.984338, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1241481572, states[0] = -95.005054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1244494803, states[0] = -95.006776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1247515314, states[0] = 22.655513, states[40]= 0.018792
Saving checkpoint... 
Iteration: 1255763919, states[0] = -94.902415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1268816384, states[0] = -94.949315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1281506646, states[0] = 26.216242, states[40]= 0.107659
Saving checkpoint... 
Iteration: 1293650758, states[0] = -66.510914, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1306717487, states[0] = -94.834319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1310496560, states[0] = -95.006955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1313320783, states[0] = -94.952205, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1318511813, states[0] = 23.310494, states[40]= 0.036259
Saving checkpoint... 
Iteration: 1322240772, states[0] = -94.872223, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1327288358, states[0] = -94.927355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1338213843, states[0] = -94.827668, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1344525837, states[0] = 20.476042, states[40]= 0.007292
Saving checkpoint... 
Iteration: 1348257406, states[0] = -94.894583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1351399174, states[0] = -94.987649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1361652238, states[0] = -68.330453, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1372920949, states[0] = -94.993602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1378329031, states[0] = -94.957302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1384570914, states[0] = 3.924309, states[40]= 0.004575
Saving checkpoint... 
Iteration: 1392535967, states[0] = 17.469436, states[40]= 0.005634
Saving checkpoint... 
Iteration: 1398075069, states[0] = 1.913588, states[40]= 0.004393
Saving checkpoint... 
Iteration: 1401363282, states[0] = -94.974652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1404862139, states[0] = -94.974159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1408264658, states[0] = -94.903187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1414026371, states[0] = 20.337730, states[40]= 0.007139
Saving checkpoint... 
Iteration: 1419225453, states[0] = -94.848117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1437582192, states[0] = -2.016005, states[40]= 0.003867
Saving checkpoint... 
Iteration: 1456224480, states[0] = -94.846454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1474748739, states[0] = -94.883326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1483687514, states[0] = -94.756052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1494848430, states[0] = -94.967782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1513021665, states[0] = -55.737146, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1531568773, states[0] = -2.125153, states[40]= 0.004335
Saving checkpoint... 
Iteration: 1549238734, states[0] = 14.168294, states[40]= 0.006250
Saving checkpoint... 
Iteration: 1567405116, states[0] = -95.204783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1585850392, states[0] = 8.283502, states[40]= 0.005578
Saving checkpoint... 
Iteration: 1604521985, states[0] = -59.436331, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1622330099, states[0] = -95.253059, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1640574584, states[0] = -95.147952, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1659174238, states[0] = -95.147456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1678168835, states[0] = -95.298123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1697089644, states[0] = -95.315100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1715801696, states[0] = -36.215434, states[40]= 0.000214
Saving checkpoint... 
Iteration: 1734458317, states[0] = -95.041541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1753376709, states[0] = -95.154214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1772375757, states[0] = -95.304352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1791303341, states[0] = 37.438768, states[40]= 0.096072
Saving checkpoint... 
Iteration: 1809805727, states[0] = -94.998316, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1827722934, states[0] = -94.879644, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1846367627, states[0] = -94.996900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1865208717, states[0] = -94.829775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1883841633, states[0] = -94.970911, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1902202863, states[0] = -94.810222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1905308893, states[0] = -94.947324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1909661021, states[0] = -81.265675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1927099873, states[0] = -15.960309, states[40]= 0.001312
Saving checkpoint... 
Iteration: 1945960427, states[0] = -95.002492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1964180344, states[0] = -94.609638, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_841.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_841_0_r647235538_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_841_0_r647235538_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 110.992410
     * GNaL_b in INaL: 0.006092
     * Gto_b in Ito: 0.082576
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.030135
     * GKs_b in IKs: 0.001875
     * GK1_b in IK1: 0.147675
     * Gncx_b in INaCa_i: 0.000971
     * Pnak_b in INaK: 73.941364
     * GKb_b in IKb: 0.003670
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.054390
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1964180344
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.609638 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading resultsTime...
Loading resultsAPD90...
Loading resultsAPD75...
Loading resultsAPD50...
Loading resultsAPD25...
Loading resultsAPD10...
Loading resultsTriangulation...
Loading resultsMaxV...
Loading resultsMinV...
Loading resultsMaxDiffV...
Loading resultsMinDiffV...
Copy resultsTime...
Copy resultsAPD90...
Copy resultsAPD75...
Copy resultsAPD50...
Copy resultsAPD25...
Copy resultsAPD10...
Copy resultsTriangulation...
Copy resultsMaxV...
Copy resultsMinV...
Copy resultsMaxDiffV...
Copy resultsMinDiffV...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1966882689, states[0] = -94.982475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1970365976, states[0] = -94.975990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1980035432, states[0] = 17.640655, states[40]= 0.005682
Saving checkpoint... 
Iteration: 1991135135, states[0] = -49.436332, states[40]= 0.000029
Saving checkpoint... 
Iteration: 1994810121, states[0] = -94.944786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1997770972, states[0] = -94.910096, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2000634816, states[0] = -49.099912, states[40]= 0.000030
Saving checkpoint... 
Iteration: 2003399191, states[0] = -94.987481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2006236978, states[0] = -94.866379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2009106063, states[0] = -21.565580, states[40]= 0.000862
Saving checkpoint... 
Iteration: 2011712161, states[0] = -94.824316, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2014154764, states[0] = -71.627177, states[40]= 0.000001
Saving checkpoint... 
Iteration: 2017282109, states[0] = -94.921292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2020374802, states[0] = -94.979073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2023661768, states[0] = -82.108837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2026205001, states[0] = -94.810503, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2029003397, states[0] = 35.905683, states[40]= 0.122027
Saving checkpoint... 
Iteration: 2032262275, states[0] = -94.900144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2035463831, states[0] = -95.002000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2038816408, states[0] = -94.948965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2041903437, states[0] = -94.988584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2045243584, states[0] = -94.875916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2048242911, states[0] = -94.874951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2051358046, states[0] = -94.972032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2054482972, states[0] = -95.004833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2057460052, states[0] = -95.001318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2060439917, states[0] = -94.997531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2063794444, states[0] = -94.932275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2067094760, states[0] = -11.299675, states[40]= 0.002026
Saving checkpoint... 
Iteration: 2069955043, states[0] = -95.000424, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2073112879, states[0] = -27.839217, states[40]= 0.000565
Saving checkpoint... 
Iteration: 2076540051, states[0] = 16.083110, states[40]= 0.005347
Saving checkpoint... 
Iteration: 2079687339, states[0] = -94.754349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2082912761, states[0] = -94.991115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2086044766, states[0] = 14.405832, states[40]= 0.005138
Saving checkpoint... 
Iteration: 2089410190, states[0] = -94.990415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2092630263, states[0] = -44.420845, states[40]= 0.000064
Saving checkpoint... 
Iteration: 2095908594, states[0] = -94.989970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2098548341, states[0] = 13.095433, states[40]= 0.005037
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.882801
 - CaMKt in component CaMK (millimolar): 0.006595
 - cass in component intracellular_ions (millimolar): 0.000072
 - nai in component intracellular_ions (millimolar): 6.419571
 - nass in component intracellular_ions (millimolar): 6.419629
 - ki in component intracellular_ions (millimolar): 145.566116
 - kss in component intracellular_ions (millimolar): 145.566097
 - cansr in component intracellular_ions (millimolar): 1.280358
 - cajsr in component intracellular_ions (millimolar): 1.242320
 - cai in component intracellular_ions (millimolar): 0.000073
 - m in component INa (dimensionless): 0.003625
 - hf in component INa (dimensionless): 0.879670
 - hs in component INa (dimensionless): 0.879665
 - j in component INa (dimensionless): 0.879636
 - hsp in component INa (dimensionless): 0.725207
 - jp in component INa (dimensionless): 0.879616
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.707922
 - hLp in component INaL (dimensionless): 0.446954
 - a in component Ito (dimensionless): 0.000624
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.615628
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.689051
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.931448
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999871
 - jca in component ICaL (dimensionless): 0.999975
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001484
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.344901
 - xs1 in component IKs (dimensionless): 0.249867
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997342
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
19:07:03 (14924): called boinc_finish(0)

</stderr_txt>
]]>