𝕏

Task 55385857

Name HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_517_0
Workunit 26299983
Created 30 Jun 2024, 3:46:48 UTC
Sent 30 Jun 2024, 5:12:25 UTC
Report deadline 3 Jul 2024, 14:48:25 UTC
Received 30 Jun 2024, 14:06:32 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 227241
Run time 2 hours 56 min 23 sec
CPU time 2 hours 53 min
Validate state Valid
Credit 58.64
Device peak FLOPS 2.94 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.19 MB
Peak swap size 6.22 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_517.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_517_0_r1180501899_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054548873570_ORdGradInc_k_25-Pueyo_APDR-conf_517_0_r1180501899_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 90.565225
     * GNaL_b in INaL: 0.006006
     * Gto_b in Ito: 0.076147
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.030635
     * GKs_b in IKs: 0.001798
     * GK1_b in IK1: 0.174860
     * Gncx_b in INaCa_i: 0.000954
     * Pnak_b in INaK: 67.809169
     * GKb_b in IKb: 0.003885
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.044972
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11996235, states[0] = -95.088230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 24468664, states[0] = -95.061608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 38046194, states[0] = 13.104609, states[40]= 0.005095
Saving checkpoint... 
Iteration: 51696631, states[0] = -94.855802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 65366678, states[0] = -95.009126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 79022020, states[0] = 21.378393, states[40]= 0.008296
Saving checkpoint... 
Iteration: 92707509, states[0] = -94.862954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 106063073, states[0] = 6.706241, states[40]= 0.004821
Saving checkpoint... 
Iteration: 119487546, states[0] = -95.026293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 132894151, states[0] = -95.008157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 146381443, states[0] = -95.003875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 159813085, states[0] = -94.973131, states[40]= 0.000000
Saving checkpoint... 
Iteration: 173274059, states[0] = -94.943745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 186310301, states[0] = -94.971006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 199280284, states[0] = -94.948925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 210825966, states[0] = -94.979913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 223386269, states[0] = -95.004365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 236817325, states[0] = -94.974969, states[40]= 0.000000
Saving checkpoint... 
Iteration: 250152202, states[0] = -71.601034, states[40]= 0.000001
Saving checkpoint... 
Iteration: 263628506, states[0] = -44.021701, states[40]= 0.000073
Saving checkpoint... 
Iteration: 277088517, states[0] = -7.548654, states[40]= 0.002838
Saving checkpoint... 
Iteration: 290468391, states[0] = -95.021451, states[40]= 0.000000
Saving checkpoint... 
Iteration: 303602966, states[0] = -20.183583, states[40]= 0.000967
Saving checkpoint... 
Iteration: 317087885, states[0] = -7.059873, states[40]= 0.002943
Saving checkpoint... 
Iteration: 330581578, states[0] = -2.661988, states[40]= 0.003827
Saving checkpoint... 
Iteration: 344045915, states[0] = 13.663659, states[40]= 0.005096
Saving checkpoint... 
Iteration: 357003749, states[0] = 33.120007, states[40]= 0.152402
Saving checkpoint... 
Iteration: 370019915, states[0] = 21.943629, states[40]= 0.009737
Saving checkpoint... 
Iteration: 383459132, states[0] = -95.020028, states[40]= 0.000000
Saving checkpoint... 
Iteration: 396798060, states[0] = -94.962376, states[40]= 0.000000
Saving checkpoint... 
Iteration: 409403180, states[0] = -95.008834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 422870604, states[0] = -94.999050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 436359493, states[0] = -94.994955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 449826655, states[0] = -94.979967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 463211092, states[0] = -94.863625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 476624811, states[0] = -40.370893, states[40]= 0.000125
Saving checkpoint... 
Iteration: 489219217, states[0] = -94.876709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 501655750, states[0] = -77.436315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 514789783, states[0] = -94.956182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 528092992, states[0] = -11.224503, states[40]= 0.002078
Saving checkpoint... 
Iteration: 541567518, states[0] = 4.809959, states[40]= 0.004711
Saving checkpoint... 
Iteration: 555046469, states[0] = 13.453630, states[40]= 0.005083
Saving checkpoint... 
Iteration: 567644378, states[0] = -61.200308, states[40]= 0.000004
Saving checkpoint... 
Iteration: 581124849, states[0] = -40.407688, states[40]= 0.000125
Saving checkpoint... 
Iteration: 594392725, states[0] = -95.005901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 607879002, states[0] = -95.001748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 621242970, states[0] = -94.909841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 634739496, states[0] = -94.905438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 646308157, states[0] = -94.969023, states[40]= 0.000000
Saving checkpoint... 
Iteration: 657998716, states[0] = -95.024880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 669596678, states[0] = -14.471658, states[40]= 0.001533
Saving checkpoint... 
Iteration: 681148979, states[0] = -66.986481, states[40]= 0.000002
Saving checkpoint... 
Iteration: 692756591, states[0] = -94.925613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 704673064, states[0] = -94.577621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 718064376, states[0] = 6.220515, states[40]= 0.004794
Saving checkpoint... 
Iteration: 727225123, states[0] = -94.885524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 738372313, states[0] = -94.999443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 750731087, states[0] = -94.894082, states[40]= 0.000000
Saving checkpoint... 
Iteration: 763118396, states[0] = -34.296107, states[40]= 0.000292
Saving checkpoint... 
Iteration: 775479068, states[0] = -95.022547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 787818645, states[0] = -94.975312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 800198526, states[0] = -94.841532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 812464818, states[0] = -95.020600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 824892300, states[0] = -95.005636, states[40]= 0.000000
Saving checkpoint... 
Iteration: 837364184, states[0] = -94.996482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 849778000, states[0] = -94.946322, states[40]= 0.000000
Saving checkpoint... 
Iteration: 861242504, states[0] = -94.909109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 874526836, states[0] = 20.197833, states[40]= 0.006681
Saving checkpoint... 
Iteration: 886880627, states[0] = -95.002092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 899048419, states[0] = 12.709254, states[40]= 0.005044
Saving checkpoint... 
Iteration: 912208498, states[0] = -94.858980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 924932973, states[0] = -95.015180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 938138576, states[0] = -54.609861, states[40]= 0.000013
Saving checkpoint... 
Iteration: 951335704, states[0] = -94.984268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 963601540, states[0] = -18.882790, states[40]= 0.001056
Saving checkpoint... 
Iteration: 976624486, states[0] = -40.055810, states[40]= 0.000131
Saving checkpoint... 
Iteration: 989816986, states[0] = -94.974220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1002780661, states[0] = -94.948507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1015127871, states[0] = -43.382045, states[40]= 0.000080
Saving checkpoint... 
Iteration: 1028251238, states[0] = -94.919445, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1041417703, states[0] = -95.011920, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1054624639, states[0] = -40.203832, states[40]= 0.000128
Saving checkpoint... 
Iteration: 1067831845, states[0] = -94.982276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1080243589, states[0] = -94.910319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1093355019, states[0] = -94.992771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1106611553, states[0] = -28.001071, states[40]= 0.000582
Saving checkpoint... 
Iteration: 1119832490, states[0] = -94.982569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1133062290, states[0] = 7.125075, states[40]= 0.004837
Saving checkpoint... 
Iteration: 1146195520, states[0] = -94.835789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1159382557, states[0] = -95.002528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1172205400, states[0] = -94.853498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1185405974, states[0] = -95.009054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1198605676, states[0] = -22.649496, states[40]= 0.000835
Saving checkpoint... 
Iteration: 1211095512, states[0] = -13.429662, states[40]= 0.001691
Saving checkpoint... 
Iteration: 1223832762, states[0] = -94.982641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1236476545, states[0] = -95.021936, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1249192617, states[0] = -94.830213, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1261639517, states[0] = -55.646304, states[40]= 0.000011
Saving checkpoint... 
Iteration: 1274238308, states[0] = -94.903497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1286468000, states[0] = -95.020756, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1298988915, states[0] = -95.023404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1312028945, states[0] = 19.578663, states[40]= 0.006288
Saving checkpoint... 
Iteration: 1325226788, states[0] = -94.887589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1338394109, states[0] = -95.005823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1351522929, states[0] = 21.241085, states[40]= 0.007887
Saving checkpoint... 
Iteration: 1364698279, states[0] = -94.840727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1377604241, states[0] = -21.343547, states[40]= 0.000900
Saving checkpoint... 
Iteration: 1390799576, states[0] = -94.962817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1403994857, states[0] = -95.024002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1416567585, states[0] = 4.779387, states[40]= 0.004709
Saving checkpoint... 
Iteration: 1429741154, states[0] = -94.907053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1434873942, states[0] = -94.999561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1447284613, states[0] = -94.951504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1460411217, states[0] = -95.010160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1473406353, states[0] = -95.008968, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1486505440, states[0] = 28.078314, states[40]= 0.134828
Saving checkpoint... 
Iteration: 1499674271, states[0] = -94.651477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1512791393, states[0] = -95.124755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1525619845, states[0] = -55.943416, states[40]= 0.000011
Saving checkpoint... 
Iteration: 1538531062, states[0] = -72.404747, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1551453639, states[0] = -94.999025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1564359075, states[0] = -95.073782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1576424558, states[0] = -95.207699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1589306429, states[0] = -95.183525, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1602220206, states[0] = -95.205065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1615122913, states[0] = -95.209527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1628018340, states[0] = -95.203874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1640925862, states[0] = -95.214262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1653744461, states[0] = -93.906785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1666552283, states[0] = 6.814660, states[40]= 0.005530
Saving checkpoint... 
Iteration: 1679445691, states[0] = 10.277554, states[40]= 0.005811
Saving checkpoint... 
Iteration: 1692316698, states[0] = 22.465481, states[40]= 0.015400
Saving checkpoint... 
Iteration: 1705203440, states[0] = 35.523979, states[40]= 0.124761
Saving checkpoint... 
Iteration: 1717253184, states[0] = 6.315655, states[40]= 0.005491
Saving checkpoint... 
Iteration: 1730161813, states[0] = 1.212803, states[40]= 0.004970
Saving checkpoint... 
Iteration: 1743062885, states[0] = 0.513270, states[40]= 0.004873
Saving checkpoint... 
Iteration: 1755915167, states[0] = 22.918136, states[40]= 0.019104
Saving checkpoint... 
Iteration: 1768817400, states[0] = 22.251960, states[40]= 0.014130
Saving checkpoint... 
Iteration: 1781732367, states[0] = 16.626983, states[40]= 0.006783
Saving checkpoint... 
Iteration: 1794640446, states[0] = 12.878284, states[40]= 0.006086
Saving checkpoint... 
Iteration: 1807539534, states[0] = 15.325452, states[40]= 0.005292
Saving checkpoint... 
Iteration: 1820457488, states[0] = -95.050183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1833362622, states[0] = -95.017203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1846206463, states[0] = -94.870260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1859105749, states[0] = -23.391762, states[40]= 0.000800
Saving checkpoint... 
Iteration: 1871948910, states[0] = -95.024563, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1884760340, states[0] = -94.933797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1897863777, states[0] = -94.998981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1911019183, states[0] = 22.077054, states[40]= 0.010406
Saving checkpoint... 
Iteration: 1924198245, states[0] = -94.841845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1937789835, states[0] = -94.956337, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1951067922, states[0] = 4.605055, states[40]= 0.004698
Saving checkpoint... 
Iteration: 1963223364, states[0] = -94.882584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1976866611, states[0] = -94.996940, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1990498813, states[0] = -95.024227, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2004097921, states[0] = -15.600948, states[40]= 0.001382
Saving checkpoint... 
Iteration: 2017711099, states[0] = -94.862704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2031354205, states[0] = -94.991864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2045013342, states[0] = 23.222926, states[40]= 0.024478
Saving checkpoint... 
Iteration: 2058606618, states[0] = -23.507889, states[40]= 0.000795
Saving checkpoint... 
Iteration: 2072260032, states[0] = -94.928368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2085489397, states[0] = -95.022923, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2099136646, states[0] = -52.510802, states[40]= 0.000019
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.899938
 - CaMKt in component CaMK (millimolar): 0.006958
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.650293
 - nass in component intracellular_ions (millimolar): 6.650351
 - ki in component intracellular_ions (millimolar): 145.328023
 - kss in component intracellular_ions (millimolar): 145.328005
 - cansr in component intracellular_ions (millimolar): 1.308994
 - cajsr in component intracellular_ions (millimolar): 1.270874
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003619
 - hf in component INa (dimensionless): 0.879968
 - hs in component INa (dimensionless): 0.879963
 - j in component INa (dimensionless): 0.879938
 - hsp in component INa (dimensionless): 0.725771
 - jp in component INa (dimensionless): 0.879920
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.709327
 - hLp in component INaL (dimensionless): 0.450340
 - a in component Ito (dimensionless): 0.000624
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.618207
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.692477
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.932673
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999876
 - jca in component ICaL (dimensionless): 0.999976
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001592
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.332071
 - xs1 in component IKs (dimensionless): 0.246060
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997338
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
08:05:19 (8336): called boinc_finish(0)

</stderr_txt>
]]>


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