𝕏

Task 55381792

Name HuVeMOp_20240630034910519118_ORdGradInc_k_25-Pueyo_APDR-conf_32_1
Workunit 26298117
Created 30 Jun 2024, 1:51:00 UTC
Sent 30 Jun 2024, 4:33:17 UTC
Report deadline 3 Jul 2024, 14:09:17 UTC
Received 30 Jun 2024, 21:39:27 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 220836
Run time 53 min 46 sec
CPU time 46 min 22 sec
Validate state Valid
Credit 56.98
Device peak FLOPS 5.24 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 2.70 MB
Peak swap size 391.88 GB
Peak disk usage 0.52 MB

Stderr output

<core_client_version>7.20.4</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630034910519118_ORdGradInc_k_25-Pueyo_APDR-conf_32.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630034910519118_ORdGradInc_k_25-Pueyo_APDR-conf_32_1_r1668645087_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630034910519118_ORdGradInc_k_25-Pueyo_APDR-conf_32_1_r1668645087_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 104.514765
     * GNaL_b in INaL: 0.004920
     * Gto_b in Ito: 0.079691
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030103
     * GKs_b in IKs: 0.002009
     * GK1_b in IK1: 0.148226
     * Gncx_b in INaCa_i: 0.000972
     * Pnak_b in INaK: 68.135713
     * GKb_b in IKb: 0.003736
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.022508
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 4335789, states[0] = -94.982710, states[40]= 0.000000
Saving checkpoint... 
Iteration: 8233084, states[0] = -94.860857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 12207435, states[0] = -94.793748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 15682617, states[0] = -94.715544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 19923668, states[0] = -94.956768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 24347135, states[0] = -94.917129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 28970880, states[0] = -94.948711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 32548238, states[0] = 11.546941, states[40]= 0.005111
Saving checkpoint... 
Iteration: 37624753, states[0] = -45.189047, states[40]= 0.000060
Saving checkpoint... 
Iteration: 41287352, states[0] = -94.847024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 46071078, states[0] = 1.531889, states[40]= 0.004509
Saving checkpoint... 
Iteration: 50263242, states[0] = -94.811386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 54357626, states[0] = -94.886128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 58848795, states[0] = -94.878592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 62926581, states[0] = -94.906413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 66981220, states[0] = -94.915682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 71683788, states[0] = -94.631059, states[40]= 0.000000
Saving checkpoint... 
Iteration: 75008457, states[0] = 24.414183, states[40]= 0.075604
Saving checkpoint... 
Iteration: 79079221, states[0] = -2.759234, states[40]= 0.003873
Saving checkpoint... 
Iteration: 82919733, states[0] = -94.896573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 86995595, states[0] = -94.910737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 91562112, states[0] = 6.313976, states[40]= 0.004865
Saving checkpoint... 
Iteration: 95629014, states[0] = -47.620346, states[40]= 0.000041
Saving checkpoint... 
Iteration: 100124454, states[0] = -43.044567, states[40]= 0.000083
Saving checkpoint... 
Iteration: 104993353, states[0] = -94.906788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 108191998, states[0] = -94.658015, states[40]= 0.000000
Saving checkpoint... 
Iteration: 112956807, states[0] = -94.899536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 117862259, states[0] = -94.868753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 122893759, states[0] = -94.881390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 127459050, states[0] = -94.898525, states[40]= 0.000000
Saving checkpoint... 
Iteration: 131207680, states[0] = -94.692724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 136502327, states[0] = 42.583986, states[40]= 0.107432
Saving checkpoint... 
Iteration: 141574958, states[0] = 0.079872, states[40]= 0.004311
Saving checkpoint... 
Iteration: 145261575, states[0] = -94.784078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 150278876, states[0] = -94.804527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 153689252, states[0] = -94.645073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 158476568, states[0] = -94.900008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 162164567, states[0] = -90.082711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 167389627, states[0] = -94.877551, states[40]= 0.000000
Saving checkpoint... 
Iteration: 171231726, states[0] = -94.737810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 175479895, states[0] = -94.900095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 180186893, states[0] = -94.633715, states[40]= 0.000000
Saving checkpoint... 
Iteration: 184563590, states[0] = 5.789404, states[40]= 0.004831
Saving checkpoint... 
Iteration: 188944913, states[0] = -94.893221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 192392100, states[0] = -94.877989, states[40]= 0.000000
Saving checkpoint... 
Iteration: 197045836, states[0] = 13.109129, states[40]= 0.005162
Saving checkpoint... 
Iteration: 201953539, states[0] = -94.894908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 206296711, states[0] = -94.821162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 210443175, states[0] = -94.892596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 213519753, states[0] = 21.504643, states[40]= 0.010152
Saving checkpoint... 
Iteration: 217583306, states[0] = -5.199912, states[40]= 0.003387
Saving checkpoint... 
Iteration: 220353249, states[0] = -94.860651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 225326860, states[0] = -94.844831, states[40]= 0.000000
Saving checkpoint... 
Iteration: 229272347, states[0] = -94.795771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 233791315, states[0] = -94.815916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 239118799, states[0] = -37.259886, states[40]= 0.000194
Saving checkpoint... 
Iteration: 243376709, states[0] = -94.871593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 246327825, states[0] = -94.845392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 251110551, states[0] = -29.521155, states[40]= 0.000501
Saving checkpoint... 
Iteration: 255089151, states[0] = -9.812611, states[40]= 0.002395
Saving checkpoint... 
Iteration: 259472366, states[0] = -94.898148, states[40]= 0.000000
Saving checkpoint... 
Iteration: 263888945, states[0] = -94.876397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 269056213, states[0] = 8.979060, states[40]= 0.004974
Saving checkpoint... 
Iteration: 273511767, states[0] = 23.173874, states[40]= 0.035411
Saving checkpoint... 
Iteration: 278023193, states[0] = 20.687992, states[40]= 0.007953
Saving checkpoint... 
Iteration: 282360843, states[0] = -94.864298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 287105853, states[0] = -25.142934, states[40]= 0.000714
Saving checkpoint... 
Iteration: 291477073, states[0] = -94.898881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 296421392, states[0] = -94.886840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 299674291, states[0] = -94.241906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 303033071, states[0] = 17.754807, states[40]= 0.005869
Saving checkpoint... 
Iteration: 306280517, states[0] = -94.804747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 310939809, states[0] = -94.891513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 315705890, states[0] = -94.686184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 319920965, states[0] = -94.886696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 323455067, states[0] = -94.894821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 326708951, states[0] = -94.692741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 330309588, states[0] = -94.831837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 334919613, states[0] = -94.886304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 338925205, states[0] = -94.887835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 342732676, states[0] = -94.738543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 346996711, states[0] = -94.901773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 349169209, states[0] = -93.119231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 352632630, states[0] = -50.836536, states[40]= 0.000024
Saving checkpoint... 
Iteration: 356213022, states[0] = -94.701224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 359860669, states[0] = -94.864134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 363998318, states[0] = -94.901978, states[40]= 0.000000
Saving checkpoint... 
Iteration: 368184695, states[0] = -94.618564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 372724840, states[0] = -94.724407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 377351657, states[0] = -94.859513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 381135361, states[0] = -53.613787, states[40]= 0.000015
Saving checkpoint... 
Iteration: 384388678, states[0] = -94.876166, states[40]= 0.000000
Saving checkpoint... 
Iteration: 387783835, states[0] = -94.808190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 391420059, states[0] = -94.886387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 393993209, states[0] = -94.901253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 397799153, states[0] = -94.822949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 401905823, states[0] = -94.882110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 406108820, states[0] = -27.903487, states[40]= 0.000581
Saving checkpoint... 
Iteration: 411269327, states[0] = -94.791917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 416145956, states[0] = -64.839650, states[40]= 0.000002
Saving checkpoint... 
Iteration: 420074572, states[0] = 0.344496, states[40]= 0.004344
Saving checkpoint... 
Iteration: 424207442, states[0] = -94.689451, states[40]= 0.000000
Saving checkpoint... 
Iteration: 428624455, states[0] = -42.687934, states[40]= 0.000088
Saving checkpoint... 
Iteration: 432787086, states[0] = -94.811488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 436221999, states[0] = -94.718997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 440363319, states[0] = -94.865361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 444800967, states[0] = -94.824522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 448375810, states[0] = -94.870982, states[40]= 0.000000
Saving checkpoint... 
Iteration: 452232563, states[0] = -94.738271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 457214297, states[0] = -94.703766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 461623105, states[0] = -41.375469, states[40]= 0.000107
Saving checkpoint... 
Iteration: 465291439, states[0] = -94.815754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 469598565, states[0] = -18.347824, states[40]= 0.001109
Saving checkpoint... 
Iteration: 474454125, states[0] = -94.894524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 478921007, states[0] = -94.886596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 483590877, states[0] = -11.304502, states[40]= 0.002096
Saving checkpoint... 
Iteration: 488538682, states[0] = 15.796556, states[40]= 0.005442
Saving checkpoint... 
Iteration: 492156438, states[0] = -78.581063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 497285399, states[0] = -94.809733, states[40]= 0.000000
Saving checkpoint... 
Iteration: 501275852, states[0] = -94.799468, states[40]= 0.000000
Saving checkpoint... 
Iteration: 506561660, states[0] = 6.658649, states[40]= 0.004876
Saving checkpoint... 
Iteration: 510702740, states[0] = -94.679121, states[40]= 0.000000
Saving checkpoint... 
Iteration: 514529493, states[0] = 18.906705, states[40]= 0.006318
Saving checkpoint... 
Iteration: 519185627, states[0] = -94.625225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 523188832, states[0] = -94.641710, states[40]= 0.000000
Saving checkpoint... 
Iteration: 527916756, states[0] = -94.885359, states[40]= 0.000000
Saving checkpoint... 
Iteration: 532228554, states[0] = -94.731119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 535563800, states[0] = 5.705160, states[40]= 0.004826
Saving checkpoint... 
Iteration: 540155591, states[0] = -77.303461, states[40]= 0.000000
Saving checkpoint... 
Iteration: 543872237, states[0] = -94.869379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 548054524, states[0] = 9.674830, states[40]= 0.005000
Saving checkpoint... 
Iteration: 551201306, states[0] = -94.675876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 555745432, states[0] = -94.759243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 558560866, states[0] = 7.005831, states[40]= 0.004893
Saving checkpoint... 
Iteration: 562640019, states[0] = -58.418001, states[40]= 0.000007
Saving checkpoint... 
Iteration: 566305843, states[0] = -94.828612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 570129096, states[0] = -47.276913, states[40]= 0.000043
Saving checkpoint... 
Iteration: 573380067, states[0] = -94.872673, states[40]= 0.000000
Saving checkpoint... 
Iteration: 578256311, states[0] = -94.775040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 582188723, states[0] = -94.641229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 586887412, states[0] = -94.875557, states[40]= 0.000000
Saving checkpoint... 
Iteration: 590866905, states[0] = -94.866950, states[40]= 0.000000
Saving checkpoint... 
Iteration: 594055742, states[0] = 9.174756, states[40]= 0.004981
Saving checkpoint... 
Iteration: 598407893, states[0] = -94.882641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 601834587, states[0] = -94.849469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 604322196, states[0] = -94.841183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 607422577, states[0] = -94.886948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 611261504, states[0] = -94.781977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 614782657, states[0] = -94.806812, states[40]= 0.000000
Saving checkpoint... 
Iteration: 619355206, states[0] = -94.861220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 623946987, states[0] = -94.892921, states[40]= 0.000000
Saving checkpoint... 
Iteration: 627300625, states[0] = -94.824106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 631497034, states[0] = -94.901632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 635700816, states[0] = -94.674711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 639199056, states[0] = -94.670661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 643482055, states[0] = -94.899434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 646784706, states[0] = -94.808927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 650457983, states[0] = -94.895186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 654548839, states[0] = 11.948094, states[40]= 0.005094
Saving checkpoint... 
Iteration: 658519812, states[0] = 21.493547, states[40]= 0.010099
Saving checkpoint... 
Iteration: 662991680, states[0] = -94.900865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 667073769, states[0] = 0.787566, states[40]= 0.004400
Saving checkpoint... 
Iteration: 672079374, states[0] = -2.516835, states[40]= 0.003907
Saving checkpoint... 
Iteration: 677029940, states[0] = 18.767800, states[40]= 0.006251
Saving checkpoint... 
Iteration: 681292819, states[0] = -94.816937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 685119243, states[0] = -37.674364, states[40]= 0.000183
Saving checkpoint... 
Iteration: 689745131, states[0] = -94.758696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 694167506, states[0] = -92.302229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 698077538, states[0] = -1.375884, states[40]= 0.004098
Saving checkpoint... 
Iteration: 701907076, states[0] = -94.882318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 706410708, states[0] = -94.883446, states[40]= 0.000000
Saving checkpoint... 
Iteration: 710463301, states[0] = -94.896170, states[40]= 0.000000
Saving checkpoint... 
Iteration: 714278535, states[0] = -94.802318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 718086414, states[0] = -7.553589, states[40]= 0.002880
Saving checkpoint... 
Iteration: 722101605, states[0] = -21.185137, states[40]= 0.000909
Saving checkpoint... 
Iteration: 726796854, states[0] = -94.820666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 730207998, states[0] = -94.690446, states[40]= 0.000000
Saving checkpoint... 
Iteration: 734100344, states[0] = -20.008554, states[40]= 0.000982
Saving checkpoint... 
Iteration: 738477317, states[0] = -94.898613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 742001278, states[0] = 49.118975, states[40]= 0.046854
Saving checkpoint... 
Iteration: 746523160, states[0] = 20.696806, states[40]= 0.007968
Saving checkpoint... 
Iteration: 751392325, states[0] = -94.877280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 755522873, states[0] = 20.769320, states[40]= 0.008096
Saving checkpoint... 
Iteration: 758810619, states[0] = -94.832382, states[40]= 0.000000
Saving checkpoint... 
Iteration: 763556400, states[0] = 8.902408, states[40]= 0.004971
Saving checkpoint... 
Iteration: 768835966, states[0] = -94.850225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 773895946, states[0] = -94.878560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 778729860, states[0] = -94.733304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 782196892, states[0] = -94.665429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 787379142, states[0] = -94.872159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 790657171, states[0] = -79.704354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 794574503, states[0] = 0.383057, states[40]= 0.004349
Saving checkpoint... 
Iteration: 798076949, states[0] = -1.022788, states[40]= 0.004152
Saving checkpoint... 
Iteration: 803120209, states[0] = -38.593304, states[40]= 0.000161
Saving checkpoint... 
Iteration: 807002353, states[0] = 42.396752, states[40]= 0.108399
Saving checkpoint... 
Iteration: 810624143, states[0] = -42.383387, states[40]= 0.000092
Saving checkpoint... 
Iteration: 814720692, states[0] = -94.716241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 819568537, states[0] = 3.483259, states[40]= 0.004673
Saving checkpoint... 
Iteration: 823245859, states[0] = -94.759727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 827560681, states[0] = 7.086310, states[40]= 0.004897
Saving checkpoint... 
Iteration: 831113850, states[0] = -32.597639, states[40]= 0.000358
Saving checkpoint... 
Iteration: 835997526, states[0] = -94.901570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 839717129, states[0] = -94.709229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 843596360, states[0] = -16.293043, states[40]= 0.001317
Saving checkpoint... 
Iteration: 847774135, states[0] = -94.797294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 850868081, states[0] = -94.867325, states[40]= 0.000000
Saving checkpoint... 
Iteration: 854669603, states[0] = -93.265480, states[40]= 0.000000
Saving checkpoint... 
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Iteration: 1368038504, states[0] = 15.861194, states[40]= 0.005452
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Iteration: 1431832287, states[0] = -94.847481, states[40]= 0.000000
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Iteration: 1441726442, states[0] = -94.726692, states[40]= 0.000000
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Iteration: 1445438078, states[0] = -94.890375, states[40]= 0.000000
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Iteration: 1452808312, states[0] = -94.830086, states[40]= 0.000000
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Iteration: 1463956311, states[0] = -94.894341, states[40]= 0.000000
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Iteration: 1467077427, states[0] = -1.308600, states[40]= 0.004108
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Iteration: 1470786740, states[0] = -94.810480, states[40]= 0.000000
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Iteration: 1475222312, states[0] = -94.718933, states[40]= 0.000000
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Iteration: 1489097247, states[0] = -17.117925, states[40]= 0.001226
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Iteration: 1492491587, states[0] = -94.900328, states[40]= 0.000000
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Iteration: 1496731582, states[0] = -94.735893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1500358623, states[0] = 4.425963, states[40]= 0.005210
Saving checkpoint... 
Iteration: 1504756286, states[0] = -95.110548, states[40]= 0.000000
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Iteration: 1509595137, states[0] = -95.152258, states[40]= 0.000000
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Iteration: 1512873571, states[0] = -95.138070, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1517805604, states[0] = -41.292970, states[40]= 0.000109
Saving checkpoint... 
Iteration: 1520749724, states[0] = 8.297482, states[40]= 0.005667
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Iteration: 1525719012, states[0] = -95.081998, states[40]= 0.000000
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Iteration: 1529225984, states[0] = -65.547488, states[40]= 0.000002
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Iteration: 1532965114, states[0] = -95.151435, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1538174584, states[0] = -9.352100, states[40]= 0.002800
Saving checkpoint... 
Iteration: 1542383770, states[0] = -19.095482, states[40]= 0.001138
Saving checkpoint... 
Iteration: 1546875072, states[0] = -10.062297, states[40]= 0.002637
Saving checkpoint... 
Iteration: 1550486844, states[0] = -22.631218, states[40]= 0.000861
Saving checkpoint... 
Iteration: 1553236704, states[0] = -82.943704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1556402796, states[0] = 40.248798, states[40]= 0.100080
Saving checkpoint... 
Iteration: 1561277035, states[0] = -12.339887, states[40]= 0.002146
Saving checkpoint... 
Iteration: 1564147107, states[0] = -95.148843, states[40]= 0.000000
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Iteration: 1568085146, states[0] = -95.189627, states[40]= 0.000000
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Iteration: 1572510096, states[0] = -95.093596, states[40]= 0.000000
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Iteration: 1576402181, states[0] = -95.078895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1578623355, states[0] = 19.995628, states[40]= 0.009111
Saving checkpoint... 
Iteration: 1581773575, states[0] = -95.011141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1584935265, states[0] = 14.991511, states[40]= 0.006577
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Iteration: 1589271738, states[0] = -95.007165, states[40]= 0.000000
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Iteration: 1593281772, states[0] = -95.192146, states[40]= 0.000000
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Iteration: 1597767490, states[0] = -95.179307, states[40]= 0.000000
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Iteration: 1600950705, states[0] = -94.591762, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1604741650, states[0] = 11.878752, states[40]= 0.006083
Saving checkpoint... 
Iteration: 1608339376, states[0] = 12.996153, states[40]= 0.006233
Saving checkpoint... 
Iteration: 1611145981, states[0] = -93.593961, states[40]= 0.000000
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Iteration: 1615405089, states[0] = -95.090278, states[40]= 0.000000
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Iteration: 1620271962, states[0] = -95.185696, states[40]= 0.000000
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Iteration: 1624741466, states[0] = -95.151044, states[40]= 0.000000
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Iteration: 1629216009, states[0] = -95.111720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1631405285, states[0] = 29.796633, states[40]= 0.124243
Saving checkpoint... 
Iteration: 1635745970, states[0] = -93.619476, states[40]= 0.000000
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Iteration: 1639896171, states[0] = -33.404052, states[40]= 0.000320
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Iteration: 1642737941, states[0] = -95.146917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1647275235, states[0] = -95.189877, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1651529492, states[0] = 17.502535, states[40]= 0.007339
Saving checkpoint... 
Iteration: 1655511444, states[0] = -50.318179, states[40]= 0.000028
Saving checkpoint... 
Iteration: 1659558423, states[0] = -95.172946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1662931165, states[0] = 16.780392, states[40]= 0.007068
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Iteration: 1666360120, states[0] = -94.957581, states[40]= 0.000000
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Iteration: 1669499379, states[0] = -95.210135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1674014384, states[0] = 22.888550, states[40]= 0.022599
Saving checkpoint... 
Iteration: 1678163701, states[0] = -95.178908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1681612011, states[0] = -50.987948, states[40]= 0.000025
Saving checkpoint... 
Iteration: 1684853075, states[0] = 5.768622, states[40]= 0.005510
Saving checkpoint... 
Iteration: 1689350648, states[0] = 7.126248, states[40]= 0.005627
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Iteration: 1694024812, states[0] = -95.127876, states[40]= 0.000000
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Iteration: 1698789618, states[0] = -95.058622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1702880265, states[0] = -16.282279, states[40]= 0.001473
Saving checkpoint... 
Iteration: 1707098374, states[0] = -35.818724, states[40]= 0.000236
Saving checkpoint... 
Iteration: 1711591480, states[0] = -28.406108, states[40]= 0.000543
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Iteration: 1716196231, states[0] = -95.073739, states[40]= 0.000000
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Iteration: 1719146816, states[0] = -93.916285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1722611866, states[0] = 23.718847, states[40]= 0.035993
Saving checkpoint... 
Iteration: 1726485725, states[0] = -95.199812, states[40]= 0.000000
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Iteration: 1730257451, states[0] = -94.924602, states[40]= 0.000000
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Iteration: 1734121131, states[0] = -61.687520, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1738051204, states[0] = -94.661528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1742143301, states[0] = 11.006183, states[40]= 0.005987
Saving checkpoint... 
Iteration: 1745406455, states[0] = 27.569647, states[40]= 0.107004
Saving checkpoint... 
Iteration: 1748893984, states[0] = -95.068768, states[40]= 0.000000
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Iteration: 1752830907, states[0] = -95.137513, states[40]= 0.000000
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Iteration: 1756425977, states[0] = -95.129857, states[40]= 0.000000
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Iteration: 1760603206, states[0] = -95.088581, states[40]= 0.000000
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Iteration: 1764486106, states[0] = -95.050291, states[40]= 0.000000
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Iteration: 1766942726, states[0] = -95.154258, states[40]= 0.000000
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Iteration: 1770828300, states[0] = -95.133514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1774136021, states[0] = -95.145024, states[40]= 0.000000
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Iteration: 1778047891, states[0] = -95.160916, states[40]= 0.000000
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Iteration: 1783032260, states[0] = -77.034621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1784987869, states[0] = -95.201589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1788714422, states[0] = -53.781013, states[40]= 0.000016
Saving checkpoint... 
Iteration: 1791720864, states[0] = -61.366445, states[40]= 0.000004
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Iteration: 1795474203, states[0] = -95.189592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1799128272, states[0] = 18.006247, states[40]= 0.007573
Saving checkpoint... 
Iteration: 1802961199, states[0] = -94.960719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1807454995, states[0] = -94.952065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1812084687, states[0] = -8.439074, states[40]= 0.002746
Saving checkpoint... 
Iteration: 1815702099, states[0] = -94.722814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1819322778, states[0] = -94.884573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1824169235, states[0] = -93.926466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1829184489, states[0] = -94.658893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1833266830, states[0] = -94.818225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1837723030, states[0] = -94.746950, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1842283239, states[0] = -94.830047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1846794026, states[0] = -94.837867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1850836895, states[0] = -94.868286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1855756523, states[0] = -94.790505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1860386701, states[0] = -94.888220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1864946193, states[0] = -94.903984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1869763261, states[0] = -94.794093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1872999667, states[0] = -94.910719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1875978289, states[0] = -94.906783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1879543451, states[0] = 13.920699, states[40]= 0.005234
Saving checkpoint... 
Iteration: 1882422587, states[0] = -94.893391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1886921963, states[0] = -94.892330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1891648259, states[0] = -67.959154, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1895093664, states[0] = -14.045427, states[40]= 0.001622
Saving checkpoint... 
Iteration: 1897887505, states[0] = -94.879396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1900213026, states[0] = -94.704681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1903193655, states[0] = -94.660571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1907381868, states[0] = -94.876073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1912263973, states[0] = -94.787432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1916384423, states[0] = -94.876268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1920513807, states[0] = 22.701016, states[40]= 0.023279
Saving checkpoint... 
Iteration: 1924094116, states[0] = -14.324571, states[40]= 0.001579
Saving checkpoint... 
Iteration: 1927659218, states[0] = -83.090009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1932406920, states[0] = -94.883180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1936273781, states[0] = -94.797725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1941020156, states[0] = 21.405860, states[40]= 0.009793
Saving checkpoint... 
Iteration: 1945958970, states[0] = -94.895690, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1950315847, states[0] = -94.836678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1953849664, states[0] = -94.858333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1958738340, states[0] = -94.747869, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1962529913, states[0] = 18.768941, states[40]= 0.006254
Saving checkpoint... 
Iteration: 1966899918, states[0] = -94.879772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1971114624, states[0] = -33.352417, states[40]= 0.000327
Saving checkpoint... 
Iteration: 1976059666, states[0] = 7.515926, states[40]= 0.004916
Saving checkpoint... 
Iteration: 1980479443, states[0] = -94.898562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1985024419, states[0] = 20.366212, states[40]= 0.007484
Saving checkpoint... 
Iteration: 1990278442, states[0] = -94.801691, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1994709867, states[0] = -94.693852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1999514276, states[0] = 22.620820, states[40]= 0.021338
Saving checkpoint... 
Iteration: 2003661443, states[0] = -86.215911, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2007601114, states[0] = -20.736483, states[40]= 0.000936
Saving checkpoint... 
Iteration: 2012084983, states[0] = -6.444791, states[40]= 0.003121
Saving checkpoint... 
Iteration: 2016840106, states[0] = -94.852059, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2021706117, states[0] = -94.685661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2026421879, states[0] = -94.885926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2029475496, states[0] = -94.897553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2032146752, states[0] = -65.753844, states[40]= 0.000002
Saving checkpoint... 
Iteration: 2035300443, states[0] = -94.823094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2038329914, states[0] = -94.845585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2040919223, states[0] = -94.885135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2043656178, states[0] = -78.190405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2048448950, states[0] = -94.892457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2051409778, states[0] = -94.882316, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2053928680, states[0] = -94.887662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2055839714, states[0] = -94.851695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2060439176, states[0] = -94.890238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2063621093, states[0] = -39.439359, states[40]= 0.000142
Saving checkpoint... 
Iteration: 2067337244, states[0] = -94.850177, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2071825985, states[0] = -94.842875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2076357178, states[0] = -94.861283, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2080889845, states[0] = -94.875501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2085032358, states[0] = 17.991520, states[40]= 0.005945
Saving checkpoint... 
Iteration: 2089470208, states[0] = -94.896520, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2094054398, states[0] = 9.726371, states[40]= 0.005002
Saving checkpoint... 
Iteration: 2098821148, states[0] = -94.839452, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.776941
 - CaMKt in component CaMK (millimolar): 0.006991
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.610464
 - nass in component intracellular_ions (millimolar): 6.610524
 - ki in component intracellular_ions (millimolar): 145.366332
 - kss in component intracellular_ions (millimolar): 145.366313
 - cansr in component intracellular_ions (millimolar): 1.316218
 - cajsr in component intracellular_ions (millimolar): 1.278300
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003664
 - hf in component INa (dimensionless): 0.877816
 - hs in component INa (dimensionless): 0.877811
 - j in component INa (dimensionless): 0.877777
 - hsp in component INa (dimensionless): 0.721723
 - jp in component INa (dimensionless): 0.877755
 - mL in component INaL (dimensionless): 0.000051
 - hL in component INaL (dimensionless): 0.705857
 - hLp in component INaL (dimensionless): 0.446018
 - a in component Ito (dimensionless): 0.000629
 - iF in component Ito (dimensionless): 0.999867
 - iS in component Ito (dimensionless): 0.618920
 - ap in component Ito (dimensionless): 0.000320
 - iFp in component Ito (dimensionless): 0.999867
 - iSp in component Ito (dimensionless): 0.693096
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935197
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999884
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001626
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.337943
 - xs1 in component IKs (dimensionless): 0.240893
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997370
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
07:13:49 (98048): called boinc_finish(0)


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630034910519118_ORdGradInc_k_25-Pueyo_APDR-conf_32.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630034910519118_ORdGradInc_k_25-Pueyo_APDR-conf_32_1_r1668645087_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630034910519118_ORdGradInc_k_25-Pueyo_APDR-conf_32_1_r1668645087_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 104.514765
     * GNaL_b in INaL: 0.004920
     * Gto_b in Ito: 0.079691
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030103
     * GKs_b in IKs: 0.002009
     * GK1_b in IK1: 0.148226
     * Gncx_b in INaCa_i: 0.000972
     * Pnak_b in INaK: 68.135713
     * GKb_b in IKb: 0.003736
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.022508
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 2098821148
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.839452 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading resultsTime...
Loading resultsAPD90...
Loading resultsAPD75...
Loading resultsAPD50...
Loading resultsAPD25...
Loading resultsAPD10...
Loading resultsTriangulation...
Loading resultsMaxV...
Loading resultsMinV...
Loading resultsMaxDiffV...
Loading resultsMinDiffV...
Copy resultsTime...
Copy resultsAPD90...
Copy resultsAPD75...
Copy resultsAPD50...
Copy resultsAPD25...
Copy resultsAPD10...
Copy resultsTriangulation...
Copy resultsMaxV...
Copy resultsMinV...
Copy resultsMaxDiffV...
Copy resultsMinDiffV...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.776941
 - CaMKt in component CaMK (millimolar): 0.006991
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.610464
 - nass in component intracellular_ions (millimolar): 6.610524
 - ki in component intracellular_ions (millimolar): 145.366332
 - kss in component intracellular_ions (millimolar): 145.366313
 - cansr in component intracellular_ions (millimolar): 1.316218
 - cajsr in component intracellular_ions (millimolar): 1.278300
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003664
 - hf in component INa (dimensionless): 0.877816
 - hs in component INa (dimensionless): 0.877811
 - j in component INa (dimensionless): 0.877777
 - hsp in component INa (dimensionless): 0.721723
 - jp in component INa (dimensionless): 0.877755
 - mL in component INaL (dimensionless): 0.000051
 - hL in component INaL (dimensionless): 0.705857
 - hLp in component INaL (dimensionless): 0.446018
 - a in component Ito (dimensionless): 0.000629
 - iF in component Ito (dimensionless): 0.999867
 - iS in component Ito (dimensionless): 0.618920
 - ap in component Ito (dimensionless): 0.000320
 - iFp in component Ito (dimensionless): 0.999867
 - iSp in component Ito (dimensionless): 0.693096
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935197
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999884
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001626
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.337943
 - xs1 in component IKs (dimensionless): 0.240893
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997370
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
07:16:55 (7552): called boinc_finish(0)

</stderr_txt>
]]>


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