𝕏

Task 55381765

Name HuVeMOp_20240630034910519118_ORdGradInc_k_25-Drouin_EPI_5000-conf_332_0
Workunit 26298104
Created 30 Jun 2024, 1:51:00 UTC
Sent 30 Jun 2024, 4:32:17 UTC
Report deadline 3 Jul 2024, 4:32:17 UTC
Received 1 Jul 2024, 18:25:52 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241050
Run time 3 hours 4 min 19 sec
CPU time 1 hours 30 min 43 sec
Validate state Valid
Credit 42.94
Device peak FLOPS 6.58 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.38 MB
Peak swap size 3.69 MB
Peak disk usage 0.04 MB

Stderr output

<core_client_version>7.16.16</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630034910519118_ORdGradInc_k_25-Drouin_EPI_5000-conf_332.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630034910519118_ORdGradInc_k_25-Drouin_EPI_5000-conf_332_0_r668653010_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630034910519118_ORdGradInc_k_25-Drouin_EPI_5000-conf_332_0_r668653010_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 112.238903
     * GNaL_b in INaL: 0.005054
     * Gto_b in Ito: 0.077176
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.030016
     * GKs_b in IKs: 0.001942
     * GK1_b in IK1: 0.176435
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 66.052043
     * GKb_b in IKb: 0.003836
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.019665
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 600.000000
     * CL_0 in membrane: 5000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 7793295, states[0] = -94.303301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 16056828, states[0] = -94.402197, states[40]= 0.000000
Saving checkpoint... 
Iteration: 24152215, states[0] = -94.359149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 31782701, states[0] = -94.341282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 39908079, states[0] = -94.325888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48092583, states[0] = -94.353442, states[40]= 0.000000
Saving checkpoint... 
Iteration: 56333891, states[0] = -94.337161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 64689921, states[0] = -94.323910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 72733556, states[0] = -93.872971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 81096645, states[0] = -94.348905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 88853150, states[0] = -94.342881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 96822872, states[0] = -94.335116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 104749187, states[0] = -94.331446, states[40]= 0.000000
Saving checkpoint... 
Iteration: 112234880, states[0] = -94.332723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 120404687, states[0] = -94.303785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 127103255, states[0] = -94.335832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 135917635, states[0] = -94.363902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 144114543, states[0] = -94.344331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 152649914, states[0] = -39.898377, states[40]= 0.000333
Saving checkpoint... 
Iteration: 160581565, states[0] = -94.366935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 167742666, states[0] = -93.934613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 175538791, states[0] = -94.361852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 183768366, states[0] = -94.353932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 192505430, states[0] = 15.917792, states[40]= 0.571738
Saving checkpoint... 
Iteration: 200757727, states[0] = -94.371259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 209325950, states[0] = -94.342432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 218768724, states[0] = -94.354200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 225927027, states[0] = -94.365823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 233149514, states[0] = -94.371610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 242474502, states[0] = -94.335536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 250575248, states[0] = -94.367119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 258185591, states[0] = -94.372007, states[40]= 0.000000
Saving checkpoint... 
Iteration: 265089184, states[0] = 10.854365, states[40]= 0.000028
Saving checkpoint... 
Iteration: 273083104, states[0] = -94.367763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 282441881, states[0] = -94.335557, states[40]= 0.000000
Saving checkpoint... 
Iteration: 291106080, states[0] = -94.359001, states[40]= 0.000000
Saving checkpoint... 
Iteration: 300201653, states[0] = -93.653128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 308903517, states[0] = -94.350170, states[40]= 0.000000
Saving checkpoint... 
Iteration: 318558566, states[0] = -94.360444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 328217478, states[0] = -94.371383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 338650033, states[0] = -94.357150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 346630333, states[0] = -94.344980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 355681960, states[0] = -94.371252, states[40]= 0.000000
Saving checkpoint... 
Iteration: 363859144, states[0] = -94.350826, states[40]= 0.000000
Saving checkpoint... 
Iteration: 372685118, states[0] = -86.270575, states[40]= 0.000001
Saving checkpoint... 
Iteration: 381307718, states[0] = -94.352044, states[40]= 0.000000
Saving checkpoint... 
Iteration: 389342914, states[0] = -94.341075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 398395916, states[0] = -94.365763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 405525188, states[0] = -94.358501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 414876561, states[0] = -94.334960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 424413832, states[0] = -94.339766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 432761315, states[0] = -94.019869, states[40]= 0.000000
Saving checkpoint... 
Iteration: 441643202, states[0] = -94.343910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 450809940, states[0] = -94.368263, states[40]= 0.000000
Saving checkpoint... 
Iteration: 459150291, states[0] = -94.343624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 466868383, states[0] = -94.340022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 475118557, states[0] = -8.402079, states[40]= 0.000299
Saving checkpoint... 
Iteration: 485520130, states[0] = -94.356750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 494480335, states[0] = -94.338278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 502096253, states[0] = -94.336845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 510083804, states[0] = 13.476186, states[40]= 0.000015
Saving checkpoint... 
Iteration: 519188184, states[0] = -94.342413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 527145101, states[0] = -94.336098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 535580603, states[0] = -94.365294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 544435597, states[0] = -94.338412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 553752957, states[0] = -94.352073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 561240743, states[0] = -94.352366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 570342872, states[0] = -94.234541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 578124929, states[0] = -94.367963, states[40]= 0.000000
Saving checkpoint... 
Iteration: 586291348, states[0] = -94.350686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 593932094, states[0] = -94.346989, states[40]= 0.000000
Saving checkpoint... 
Iteration: 602061464, states[0] = -94.336350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 611173368, states[0] = -94.353998, states[40]= 0.000000
Saving checkpoint... 
Iteration: 620193989, states[0] = -93.159530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 627615377, states[0] = -5.602430, states[40]= 0.000281
Saving checkpoint... 
Iteration: 635315648, states[0] = -94.183400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 643969408, states[0] = -94.345680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 651966408, states[0] = -94.337058, states[40]= 0.000000
Saving checkpoint... 
Iteration: 659987615, states[0] = -94.331941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 668026418, states[0] = -94.356424, states[40]= 0.000000
Saving checkpoint... 
Iteration: 677068012, states[0] = -94.335609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 684320961, states[0] = -94.338789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 692412531, states[0] = -94.332213, states[40]= 0.000000
Saving checkpoint... 
Iteration: 700503182, states[0] = -94.350846, states[40]= 0.000000
Saving checkpoint... 
Iteration: 708126063, states[0] = -94.366863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 717415200, states[0] = -94.331971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 725775087, states[0] = -94.366817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 732983495, states[0] = -94.344795, states[40]= 0.000000
Saving checkpoint... 
Iteration: 740658108, states[0] = -94.367569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 747799059, states[0] = -94.142686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 756132401, states[0] = -94.354050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 766114667, states[0] = -94.354557, states[40]= 0.000000
Saving checkpoint... 
Iteration: 773838610, states[0] = -94.347738, states[40]= 0.000000
Saving checkpoint... 
Iteration: 781521704, states[0] = -94.343311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 789661944, states[0] = -94.333595, states[40]= 0.000000
Saving checkpoint... 
Iteration: 797288391, states[0] = -94.332317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 805518046, states[0] = -94.353468, states[40]= 0.000000
Saving checkpoint... 
Iteration: 813155753, states[0] = -94.366881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 820742617, states[0] = -94.366689, states[40]= 0.000000
Saving checkpoint... 
Iteration: 828557248, states[0] = -94.356001, states[40]= 0.000000
Saving checkpoint... 
Iteration: 836818163, states[0] = -94.337478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 844886049, states[0] = -94.331069, states[40]= 0.000000
Saving checkpoint... 
Iteration: 852302005, states[0] = -94.331708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 859773521, states[0] = -94.331896, states[40]= 0.000000
Saving checkpoint... 
Iteration: 867123343, states[0] = -94.333312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 876392785, states[0] = -94.345439, states[40]= 0.000000
Saving checkpoint... 
Iteration: 885143425, states[0] = -33.205984, states[40]= 0.000505
Saving checkpoint... 
Iteration: 893124976, states[0] = -94.365178, states[40]= 0.000000
Saving checkpoint... 
Iteration: 901396602, states[0] = -94.345123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 908441876, states[0] = -94.359541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 916847333, states[0] = -94.336335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 924764146, states[0] = -94.331405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 932925749, states[0] = -94.316410, states[40]= 0.000000
Saving checkpoint... 
Iteration: 940805445, states[0] = -94.364065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 948490517, states[0] = -94.357370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 956611209, states[0] = -94.339947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 965717218, states[0] = -94.365766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 975226466, states[0] = -93.838619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 983083011, states[0] = -94.361562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 992000770, states[0] = -94.333610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1000395225, states[0] = -94.293122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1008867687, states[0] = -94.344897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1017308426, states[0] = -94.330188, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1025481835, states[0] = -94.341655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1033180581, states[0] = -94.365260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1042834435, states[0] = -94.216322, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1050574728, states[0] = -94.360149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1058015811, states[0] = -94.350738, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1065537902, states[0] = -94.355018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1075812553, states[0] = -94.362652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1083875510, states[0] = -94.344033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1091178844, states[0] = -94.349570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1099034432, states[0] = -94.340226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1106711898, states[0] = -94.336792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1114207417, states[0] = -94.336802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1122617436, states[0] = -7.381654, states[40]= 0.000295
Saving checkpoint... 
Iteration: 1130664692, states[0] = -94.364232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1138316791, states[0] = -94.361966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1146782772, states[0] = -94.335274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1154593938, states[0] = -94.331081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1161901030, states[0] = -94.333400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1170267036, states[0] = -94.036068, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1178583401, states[0] = -94.351979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1187232173, states[0] = -94.329374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1196168099, states[0] = -94.348983, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1204824943, states[0] = -94.328381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1212936059, states[0] = -94.320014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1221703295, states[0] = -94.335919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1229666083, states[0] = -94.329648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1237705620, states[0] = -93.693895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1245356520, states[0] = -94.248499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1253127251, states[0] = -94.362093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1261125109, states[0] = -94.349820, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1268579823, states[0] = -94.351306, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1276583174, states[0] = -94.337656, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1284362423, states[0] = -94.332856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1291351312, states[0] = -94.342817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1298688858, states[0] = -94.347415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1306753076, states[0] = -94.334331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1316179839, states[0] = -94.347545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1324160985, states[0] = -94.335759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1332288222, states[0] = -94.327571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1340388985, states[0] = -94.284438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1349542329, states[0] = -94.329939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1356713646, states[0] = -94.334544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1364229386, states[0] = -94.334212, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1372339256, states[0] = -94.326772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1379070911, states[0] = -94.336992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1386614295, states[0] = -94.336074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1395429318, states[0] = -94.314494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1403215974, states[0] = -94.361907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1411489724, states[0] = -94.338420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1420998461, states[0] = -94.352891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1428538195, states[0] = -94.351371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1436513556, states[0] = -94.337677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1444928063, states[0] = -94.325415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1452555542, states[0] = 24.095406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1460365488, states[0] = -94.258123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1469058919, states[0] = -94.336437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1477505546, states[0] = 16.096571, states[40]= 0.541927
Saving checkpoint... 
Iteration: 1484783201, states[0] = -94.326262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1492877292, states[0] = -94.271347, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.200372
 - CaMKt in component CaMK (millimolar): 0.001709
 - cass in component intracellular_ions (millimolar): 0.000101
 - nai in component intracellular_ions (millimolar): 7.214545
 - nass in component intracellular_ions (millimolar): 7.214681
 - ki in component intracellular_ions (millimolar): 144.488525
 - kss in component intracellular_ions (millimolar): 144.488512
 - cansr in component intracellular_ions (millimolar): 2.398555
 - cajsr in component intracellular_ions (millimolar): 2.398889
 - cai in component intracellular_ions (millimolar): 0.000106
 - m in component INa (dimensionless): 0.003884
 - hf in component INa (dimensionless): 0.867285
 - hs in component INa (dimensionless): 0.867285
 - j in component INa (dimensionless): 0.867287
 - hsp in component INa (dimensionless): 0.702334
 - jp in component INa (dimensionless): 0.867288
 - mL in component INaL (dimensionless): 0.000057
 - hL in component INaL (dimensionless): 0.710290
 - hLp in component INaL (dimensionless): 0.517161
 - a in component Ito (dimensionless): 0.000654
 - iF in component Ito (dimensionless): 0.999853
 - iS in component Ito (dimensionless): 0.999853
 - ap in component Ito (dimensionless): 0.000333
 - iFp in component Ito (dimensionless): 0.999853
 - iSp in component Ito (dimensionless): 0.999853
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998778
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005339
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.001768
 - xs1 in component IKs (dimensionless): 0.023765
 - xs2 in component IKs (dimensionless): 0.000095
 - xk1 in component IK1 (dimensionless): 0.997515
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
19:18:00 (30761): called boinc_finish(0)

</stderr_txt>
]]>


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