𝕏

Task 55377796

Name HuVeMOp_20240630034552846528_ORdGradInc_k_25-Pueyo_APDR-conf_482_1
Workunit 26296120
Created 30 Jun 2024, 1:48:46 UTC
Sent 30 Jun 2024, 4:01:28 UTC
Report deadline 3 Jul 2024, 13:37:28 UTC
Received 30 Jun 2024, 8:13:23 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 232784
Run time 1 hours 6 min 2 sec
CPU time 50 min 9 sec
Validate state Valid
Credit 59.94
Device peak FLOPS 5.12 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.16 MB
Peak swap size 5.28 MB
Peak disk usage 0.18 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630034552846528_ORdGradInc_k_25-Pueyo_APDR-conf_482.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630034552846528_ORdGradInc_k_25-Pueyo_APDR-conf_482_1_r1389971422_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630034552846528_ORdGradInc_k_25-Pueyo_APDR-conf_482_1_r1389971422_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 98.762210
     * GNaL_b in INaL: 0.004629
     * Gto_b in Ito: 0.094086
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032884
     * GKs_b in IKs: 0.001959
     * GK1_b in IK1: 0.161335
     * Gncx_b in INaCa_i: 0.000956
     * Pnak_b in INaK: 69.789113
     * GKb_b in IKb: 0.003757
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.022536
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 15833725, states[0] = -95.110448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 31230184, states[0] = -94.971440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 47791858, states[0] = -95.027598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 63997961, states[0] = -95.096600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 80722156, states[0] = -94.920658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 98029602, states[0] = 17.706722, states[40]= 0.005662
Saving checkpoint... 
Iteration: 114727409, states[0] = -94.923482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 131479339, states[0] = -95.080063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 148712622, states[0] = -94.893864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 165018500, states[0] = 20.287918, states[40]= 0.010253
Saving checkpoint... 
Iteration: 181617214, states[0] = -39.355791, states[40]= 0.000142
Saving checkpoint... 
Iteration: 198930520, states[0] = -95.068781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 215696746, states[0] = -94.859106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 232413756, states[0] = -95.064259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 249748345, states[0] = -94.952089, states[40]= 0.000000
Saving checkpoint... 
Iteration: 266528066, states[0] = 18.203802, states[40]= 0.005876
Saving checkpoint... 
Iteration: 283312128, states[0] = -95.017015, states[40]= 0.000000
Saving checkpoint... 
Iteration: 300426845, states[0] = -95.067518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 317127156, states[0] = -49.655196, states[40]= 0.000029
Saving checkpoint... 
Iteration: 333859281, states[0] = -95.044424, states[40]= 0.000000
Saving checkpoint... 
Iteration: 351050566, states[0] = 10.437108, states[40]= 0.004805
Saving checkpoint... 
Iteration: 367857391, states[0] = -95.043516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 384667854, states[0] = -94.546427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 402131600, states[0] = -54.455097, states[40]= 0.000013
Saving checkpoint... 
Iteration: 418946626, states[0] = -95.071846, states[40]= 0.000000
Saving checkpoint... 
Iteration: 435751030, states[0] = -94.955544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 452937363, states[0] = -95.069843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 469721714, states[0] = -94.909429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 486617831, states[0] = -39.945389, states[40]= 0.000130
Saving checkpoint... 
Iteration: 503960182, states[0] = -95.074383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 520808303, states[0] = -95.013971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 537653733, states[0] = -84.555201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 555035928, states[0] = 15.801138, states[40]= 0.005156
Saving checkpoint... 
Iteration: 571748075, states[0] = -94.951389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 588627487, states[0] = -50.008500, states[40]= 0.000028
Saving checkpoint... 
Iteration: 606060777, states[0] = 6.193137, states[40]= 0.004707
Saving checkpoint... 
Iteration: 622893525, states[0] = -95.057676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 639795104, states[0] = -95.003236, states[40]= 0.000000
Saving checkpoint... 
Iteration: 657127361, states[0] = -49.873524, states[40]= 0.000028
Saving checkpoint... 
Iteration: 673871896, states[0] = -95.049631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 690978663, states[0] = -95.077298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 708050230, states[0] = 10.569004, states[40]= 0.004807
Saving checkpoint... 
Iteration: 724788610, states[0] = -94.997394, states[40]= 0.000000
Saving checkpoint... 
Iteration: 742169011, states[0] = -94.622255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 758855960, states[0] = -95.042534, states[40]= 0.000000
Saving checkpoint... 
Iteration: 775534781, states[0] = 16.180427, states[40]= 0.005222
Saving checkpoint... 
Iteration: 792875207, states[0] = -95.050872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 809577366, states[0] = -2.594401, states[40]= 0.003847
Saving checkpoint... 
Iteration: 826217300, states[0] = -94.900978, states[40]= 0.000000
Saving checkpoint... 
Iteration: 843449864, states[0] = -95.072168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 860150060, states[0] = -78.281527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 876838366, states[0] = -95.033336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 894069404, states[0] = 2.057387, states[40]= 0.004454
Saving checkpoint... 
Iteration: 910753446, states[0] = -94.958393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 927379025, states[0] = -95.052254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 944545218, states[0] = 12.486991, states[40]= 0.004863
Saving checkpoint... 
Iteration: 961262383, states[0] = -94.969592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 978020792, states[0] = 19.895787, states[40]= 0.008225
Saving checkpoint... 
Iteration: 995238547, states[0] = -94.937136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1011857049, states[0] = -95.042852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1028590811, states[0] = -13.550799, states[40]= 0.001688
Saving checkpoint... 
Iteration: 1045793853, states[0] = -95.001836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1062466677, states[0] = -95.075086, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1079195250, states[0] = -94.854848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1096334972, states[0] = -95.031224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1112999710, states[0] = -95.079866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1129702241, states[0] = -94.870281, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1146986153, states[0] = -95.078041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1163705275, states[0] = -94.876709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1180474753, states[0] = -95.076314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1197718014, states[0] = -94.902032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1214418964, states[0] = -95.064786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1231107613, states[0] = -29.845423, states[40]= 0.000466
Saving checkpoint... 
Iteration: 1248347797, states[0] = -95.038118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1265078956, states[0] = -3.668797, states[40]= 0.003655
Saving checkpoint... 
Iteration: 1281818684, states[0] = -95.020823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1299053978, states[0] = 9.074641, states[40]= 0.004779
Saving checkpoint... 
Iteration: 1315795575, states[0] = -95.003114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1332545689, states[0] = 12.310469, states[40]= 0.004856
Saving checkpoint... 
Iteration: 1349781178, states[0] = -94.989815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1366483788, states[0] = -95.077533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1383184473, states[0] = -94.828204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1400394940, states[0] = -95.057542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1417152521, states[0] = -82.492428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1433776544, states[0] = -94.985049, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1450972801, states[0] = -95.075794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1467584005, states[0] = -7.489091, states[40]= 0.002873
Saving checkpoint... 
Iteration: 1484316139, states[0] = -95.018910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1501604580, states[0] = -42.755854, states[40]= 0.000080
Saving checkpoint... 
Iteration: 1518244558, states[0] = -95.270981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1534767635, states[0] = -95.311817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1551781983, states[0] = -95.188798, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1568380660, states[0] = -95.340404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1584885217, states[0] = -95.347754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1601944990, states[0] = -95.310969, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1618439083, states[0] = -95.304917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1634968762, states[0] = -95.338039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1652018543, states[0] = -95.276546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1668605509, states[0] = 26.482234, states[40]= 0.135758
Saving checkpoint... 
Iteration: 1685322768, states[0] = -95.283561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1702393222, states[0] = -95.229837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1719064880, states[0] = -3.566796, states[40]= 0.004135
Saving checkpoint... 
Iteration: 1735659066, states[0] = -95.140267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1752658463, states[0] = 1.213015, states[40]= 0.004934
Saving checkpoint... 
Iteration: 1769242093, states[0] = -94.614876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1785720572, states[0] = -67.764254, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1802714276, states[0] = -94.951242, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1819350395, states[0] = -95.080294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1835966977, states[0] = -95.100486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1853001944, states[0] = 43.473435, states[40]= 0.104980
Saving checkpoint... 
Iteration: 1869657580, states[0] = -90.806207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1886216211, states[0] = -94.904153, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1903247175, states[0] = -94.952728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1919868115, states[0] = -95.049259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1936572726, states[0] = 0.205485, states[40]= 0.004258
Saving checkpoint... 
Iteration: 1953670302, states[0] = -94.683485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1970328262, states[0] = -95.026962, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1986891882, states[0] = -95.056311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2003871663, states[0] = -95.048626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2020406188, states[0] = -95.060631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2036965591, states[0] = -95.074147, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2054126981, states[0] = -49.468845, states[40]= 0.000030
Saving checkpoint... 
Iteration: 2070730397, states[0] = -94.923225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2087338374, states[0] = -95.032345, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.954953
 - CaMKt in component CaMK (millimolar): 0.007275
 - cass in component intracellular_ions (millimolar): 0.000075
 - nai in component intracellular_ions (millimolar): 6.564936
 - nass in component intracellular_ions (millimolar): 6.564998
 - ki in component intracellular_ions (millimolar): 145.406056
 - kss in component intracellular_ions (millimolar): 145.406036
 - cansr in component intracellular_ions (millimolar): 1.335425
 - cajsr in component intracellular_ions (millimolar): 1.297437
 - cai in component intracellular_ions (millimolar): 0.000076
 - m in component INa (dimensionless): 0.003599
 - hf in component INa (dimensionless): 0.880919
 - hs in component INa (dimensionless): 0.880914
 - j in component INa (dimensionless): 0.880884
 - hsp in component INa (dimensionless): 0.727561
 - jp in component INa (dimensionless): 0.880863
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.711996
 - hLp in component INaL (dimensionless): 0.455664
 - a in component Ito (dimensionless): 0.000621
 - iF in component Ito (dimensionless): 0.999871
 - iS in component Ito (dimensionless): 0.625293
 - ap in component Ito (dimensionless): 0.000316
 - iFp in component Ito (dimensionless): 0.999871
 - iSp in component Ito (dimensionless): 0.701435
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.939810
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999900
 - jca in component ICaL (dimensionless): 0.999980
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001693
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.314053
 - xs1 in component IKs (dimensionless): 0.233974
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997323
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
04:11:02 (18712): called boinc_finish(0)

</stderr_txt>
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