𝕏

Task 55370630

Name HuVeMOp_20240630012025727263_ORdGradInc_k_25-Pueyo_APDR-conf_868_0
Workunit 26292817
Created 29 Jun 2024, 23:24:23 UTC
Sent 30 Jun 2024, 2:55:05 UTC
Report deadline 3 Jul 2024, 12:31:05 UTC
Received 30 Jun 2024, 10:07:28 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 229534
Run time 2 hours 14 min 10 sec
CPU time 2 hours 12 min 59 sec
Validate state Valid
Credit 59.86
Device peak FLOPS 4.00 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.85 MB
Peak swap size 6.38 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630012025727263_ORdGradInc_k_25-Pueyo_APDR-conf_868.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630012025727263_ORdGradInc_k_25-Pueyo_APDR-conf_868_0_r390297955_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630012025727263_ORdGradInc_k_25-Pueyo_APDR-conf_868_0_r390297955_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 93.088233
     * GNaL_b in INaL: 0.005655
     * Gto_b in Ito: 0.099910
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.033017
     * GKs_b in IKs: 0.002040
     * GK1_b in IK1: 0.146970
     * Gncx_b in INaCa_i: 0.000979
     * Pnak_b in INaK: 70.493240
     * GKb_b in IKb: 0.003749
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.034428
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 16734505, states[0] = -94.872712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 33420446, states[0] = -94.978927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 50656649, states[0] = -80.586789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 67980388, states[0] = -94.960671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 84961539, states[0] = -94.950841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 102065679, states[0] = 5.506503, states[40]= 0.004553
Saving checkpoint... 
Iteration: 119274343, states[0] = -94.843269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 136555637, states[0] = 9.696173, states[40]= 0.004630
Saving checkpoint... 
Iteration: 153591929, states[0] = -10.717164, states[40]= 0.002142
Saving checkpoint... 
Iteration: 170871869, states[0] = -94.914478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 188111180, states[0] = -28.617247, states[40]= 0.000537
Saving checkpoint... 
Iteration: 205381311, states[0] = -94.918046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 222687843, states[0] = -94.670024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 239451283, states[0] = -94.938991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 256685815, states[0] = -94.657517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 273950958, states[0] = -94.938830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 291157188, states[0] = -78.987810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 307945930, states[0] = -94.937678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 324491147, states[0] = -94.945905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 341630472, states[0] = -47.468504, states[40]= 0.000043
Saving checkpoint... 
Iteration: 358871775, states[0] = -94.913524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 376056919, states[0] = 9.230787, states[40]= 0.004627
Saving checkpoint... 
Iteration: 393095645, states[0] = -14.015680, states[40]= 0.001574
Saving checkpoint... 
Iteration: 410228453, states[0] = -94.769543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 426225358, states[0] = -94.763567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 442949572, states[0] = -94.938360, states[40]= 0.000000
Saving checkpoint... 
Iteration: 459993220, states[0] = -94.946087, states[40]= 0.000000
Saving checkpoint... 
Iteration: 477137349, states[0] = -54.692433, states[40]= 0.000013
Saving checkpoint... 
Iteration: 494119080, states[0] = -36.099562, states[40]= 0.000228
Saving checkpoint... 
Iteration: 511174715, states[0] = -94.264518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 528335196, states[0] = -94.893518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 545161472, states[0] = -85.568277, states[40]= 0.000000
Saving checkpoint... 
Iteration: 562251773, states[0] = -94.809015, states[40]= 0.000000
Saving checkpoint... 
Iteration: 579488064, states[0] = -94.945236, states[40]= 0.000000
Saving checkpoint... 
Iteration: 596495900, states[0] = -94.946354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 612950231, states[0] = -94.938365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 629564492, states[0] = 6.128636, states[40]= 0.004572
Saving checkpoint... 
Iteration: 646642122, states[0] = -59.819001, states[40]= 0.000005
Saving checkpoint... 
Iteration: 663421695, states[0] = -94.931269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 680523304, states[0] = 19.833562, states[40]= 0.006609
Saving checkpoint... 
Iteration: 697722432, states[0] = -94.757551, states[40]= 0.000000
Saving checkpoint... 
Iteration: 714956812, states[0] = -94.939657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 732222113, states[0] = -94.756882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 749492405, states[0] = -94.945737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 766437282, states[0] = -94.935274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 783534437, states[0] = 17.074967, states[40]= 0.004978
Saving checkpoint... 
Iteration: 800795460, states[0] = -94.861824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 817909973, states[0] = -94.927649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 835208903, states[0] = -94.728680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 852495482, states[0] = -94.946090, states[40]= 0.000000
Saving checkpoint... 
Iteration: 869751016, states[0] = -94.807621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 887015919, states[0] = 20.800891, states[40]= 0.014055
Saving checkpoint... 
Iteration: 903893192, states[0] = -94.921851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 920847778, states[0] = -94.900844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 938108000, states[0] = -25.604181, states[40]= 0.000677
Saving checkpoint... 
Iteration: 955265456, states[0] = -94.827927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 972492959, states[0] = -94.945637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 989806152, states[0] = -94.871410, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1007089233, states[0] = -8.374280, states[40]= 0.002614
Saving checkpoint... 
Iteration: 1024196526, states[0] = -94.698991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1041297421, states[0] = -94.863496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1058539038, states[0] = 15.636557, states[40]= 0.004781
Saving checkpoint... 
Iteration: 1075811517, states[0] = -94.875845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1093061614, states[0] = 7.345852, states[40]= 0.004604
Saving checkpoint... 
Iteration: 1110112015, states[0] = -29.382802, states[40]= 0.000501
Saving checkpoint... 
Iteration: 1127144662, states[0] = -62.627931, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1144233522, states[0] = -94.778344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1161513126, states[0] = 20.973402, states[40]= 0.024188
Saving checkpoint... 
Iteration: 1178793573, states[0] = -94.859687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1196049700, states[0] = 11.943985, states[40]= 0.004638
Saving checkpoint... 
Iteration: 1213371760, states[0] = -94.912825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1230658044, states[0] = -80.310344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1247568985, states[0] = 4.110807, states[40]= 0.004483
Saving checkpoint... 
Iteration: 1264207171, states[0] = -94.724419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1281492784, states[0] = -94.945363, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1298788572, states[0] = -94.854562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1316052541, states[0] = 10.899103, states[40]= 0.004633
Saving checkpoint... 
Iteration: 1333320473, states[0] = -94.882636, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1350572177, states[0] = 2.568656, states[40]= 0.004379
Saving checkpoint... 
Iteration: 1367863683, states[0] = -94.908897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1385169707, states[0] = -93.148895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1402441481, states[0] = -94.935764, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1419698993, states[0] = -94.704959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1436953068, states[0] = -94.938305, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1454227514, states[0] = -94.766904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1471546307, states[0] = 13.158840, states[40]= 0.004654
Saving checkpoint... 
Iteration: 1488842114, states[0] = -94.897062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1505548564, states[0] = -93.546467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1522752713, states[0] = -95.176665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1539984262, states[0] = -19.213404, states[40]= 0.001103
Saving checkpoint... 
Iteration: 1557224408, states[0] = -95.164844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1574423557, states[0] = 19.075424, states[40]= 0.007679
Saving checkpoint... 
Iteration: 1591590715, states[0] = -27.148000, states[40]= 0.000595
Saving checkpoint... 
Iteration: 1608794982, states[0] = -95.118004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1626009303, states[0] = 22.178151, states[40]= 0.060810
Saving checkpoint... 
Iteration: 1643237418, states[0] = -86.756788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1660214354, states[0] = 21.147426, states[40]= 0.020253
Saving checkpoint... 
Iteration: 1677436374, states[0] = -85.193127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1694635290, states[0] = -95.197034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1711582315, states[0] = -18.145131, states[40]= 0.001214
Saving checkpoint... 
Iteration: 1728833192, states[0] = -95.193925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1745728055, states[0] = 17.500129, states[40]= 0.006592
Saving checkpoint... 
Iteration: 1762818674, states[0] = 20.306305, states[40]= 0.010884
Saving checkpoint... 
Iteration: 1779974915, states[0] = -10.223961, states[40]= 0.002553
Saving checkpoint... 
Iteration: 1797104187, states[0] = -42.217125, states[40]= 0.000097
Saving checkpoint... 
Iteration: 1814279837, states[0] = -94.900196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1831507793, states[0] = 21.740291, states[40]= 0.089788
Saving checkpoint... 
Iteration: 1848726271, states[0] = -94.785561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1865780869, states[0] = -94.858535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1883001796, states[0] = 43.366925, states[40]= 0.097563
Saving checkpoint... 
Iteration: 1900023954, states[0] = 19.673312, states[40]= 0.006391
Saving checkpoint... 
Iteration: 1917223334, states[0] = -94.761084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1934434533, states[0] = -94.935221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1951655598, states[0] = -76.658848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1968729230, states[0] = -94.770277, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1985841414, states[0] = -94.896519, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2002882429, states[0] = -94.916921, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2020072267, states[0] = 2.521176, states[40]= 0.004375
Saving checkpoint... 
Iteration: 2037233600, states[0] = -94.777761, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2054421416, states[0] = -94.930038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2071665128, states[0] = -90.108890, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2088897925, states[0] = -94.922544, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.821513
 - CaMKt in component CaMK (millimolar): 0.007340
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.579870
 - nass in component intracellular_ions (millimolar): 6.579932
 - ki in component intracellular_ions (millimolar): 145.392346
 - kss in component intracellular_ions (millimolar): 145.392326
 - cansr in component intracellular_ions (millimolar): 1.328419
 - cajsr in component intracellular_ions (millimolar): 1.289702
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003648
 - hf in component INa (dimensionless): 0.878600
 - hs in component INa (dimensionless): 0.878594
 - j in component INa (dimensionless): 0.878561
 - hsp in component INa (dimensionless): 0.723191
 - jp in component INa (dimensionless): 0.878538
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.706864
 - hLp in component INaL (dimensionless): 0.446835
 - a in component Ito (dimensionless): 0.000627
 - iF in component Ito (dimensionless): 0.999868
 - iS in component Ito (dimensionless): 0.618138
 - ap in component Ito (dimensionless): 0.000319
 - iFp in component Ito (dimensionless): 0.999868
 - iSp in component Ito (dimensionless): 0.692576
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935861
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999887
 - jca in component ICaL (dimensionless): 0.999977
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001650
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.317607
 - xs1 in component IKs (dimensionless): 0.244028
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997358
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
02:59:57 (1688): called boinc_finish(0)

</stderr_txt>
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