𝕏

Task 55370467

Name HuVeMOp_20240630012025727263_ORdGradInc_k_25-Pueyo_APDR-conf_262_1
Workunit 26292735
Created 29 Jun 2024, 23:24:18 UTC
Sent 30 Jun 2024, 2:58:32 UTC
Report deadline 3 Jul 2024, 12:34:32 UTC
Received 2 Jul 2024, 17:53:45 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 218836
Run time 1 hours 42 min 35 sec
CPU time 58 min 53 sec
Validate state Valid
Credit 61.91
Device peak FLOPS 5.93 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.72 MB
Peak swap size 5.30 MB
Peak disk usage 0.27 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630012025727263_ORdGradInc_k_25-Pueyo_APDR-conf_262.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630012025727263_ORdGradInc_k_25-Pueyo_APDR-conf_262_1_r1902041583_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630012025727263_ORdGradInc_k_25-Pueyo_APDR-conf_262_1_r1902041583_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 94.035573
     * GNaL_b in INaL: 0.004470
     * Gto_b in Ito: 0.091919
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032008
     * GKs_b in IKs: 0.002145
     * GK1_b in IK1: 0.168026
     * Gncx_b in INaCa_i: 0.000957
     * Pnak_b in INaK: 73.306473
     * GKb_b in IKb: 0.003931
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.043139
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11381669, states[0] = -95.089609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 24731739, states[0] = -94.938666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 38151973, states[0] = -85.703534, states[40]= 0.000000
Saving checkpoint... 
Iteration: 51687702, states[0] = -94.820254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 65103102, states[0] = -26.531240, states[40]= 0.000601
Saving checkpoint... 
Iteration: 75242233, states[0] = -94.900675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 88937910, states[0] = -95.008962, states[40]= 0.000000
Saving checkpoint... 
Iteration: 102390567, states[0] = -94.994647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 116035966, states[0] = 15.454409, states[40]= 0.005216
Saving checkpoint... 
Iteration: 129589344, states[0] = -12.582527, states[40]= 0.001826
Saving checkpoint... 
Iteration: 142987460, states[0] = -95.010051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 152418711, states[0] = -94.997861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 166063332, states[0] = 4.664601, states[40]= 0.004598
Saving checkpoint... 
Iteration: 179813649, states[0] = -94.955242, states[40]= 0.000000
Saving checkpoint... 
Iteration: 193373382, states[0] = -94.983834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 206908481, states[0] = -94.994350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 220300342, states[0] = -94.945777, states[40]= 0.000000
Saving checkpoint... 
Iteration: 233579265, states[0] = -4.206454, states[40]= 0.003507
Saving checkpoint... 
Iteration: 246982443, states[0] = -95.007817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 260576349, states[0] = -2.260672, states[40]= 0.003854
Saving checkpoint... 
Iteration: 274091191, states[0] = -14.176654, states[40]= 0.001568
Saving checkpoint... 
Iteration: 287383791, states[0] = -94.986965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 300798436, states[0] = -94.944175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 314354713, states[0] = -94.976121, states[40]= 0.000000
Saving checkpoint... 
Iteration: 323792441, states[0] = -94.939568, states[40]= 0.000000
Saving checkpoint... 
Iteration: 337232915, states[0] = -94.874867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 349638022, states[0] = -61.013503, states[40]= 0.000004
Saving checkpoint... 
Iteration: 363367603, states[0] = -94.981244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 373038516, states[0] = 14.611838, states[40]= 0.005083
Saving checkpoint... 
Iteration: 386312893, states[0] = -94.954078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 395993513, states[0] = -95.008984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 409495945, states[0] = -95.009250, states[40]= 0.000000
Saving checkpoint... 
Iteration: 423075636, states[0] = -1.811813, states[40]= 0.003926
Saving checkpoint... 
Iteration: 432401027, states[0] = -94.991979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 445755475, states[0] = -94.904058, states[40]= 0.000000
Saving checkpoint... 
Iteration: 459077600, states[0] = -3.069414, states[40]= 0.003716
Saving checkpoint... 
Iteration: 472913624, states[0] = -94.995212, states[40]= 0.000000
Saving checkpoint... 
Iteration: 486165756, states[0] = -94.282893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 499572242, states[0] = 0.187003, states[40]= 0.004206
Saving checkpoint... 
Iteration: 513150799, states[0] = -78.724563, states[40]= 0.000000
Saving checkpoint... 
Iteration: 526839052, states[0] = -94.968760, states[40]= 0.000000
Saving checkpoint... 
Iteration: 540539452, states[0] = 14.276846, states[40]= 0.005043
Saving checkpoint... 
Iteration: 553840519, states[0] = -94.969463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 567267037, states[0] = -94.916531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 580722421, states[0] = -94.858624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 590041886, states[0] = 13.390033, states[40]= 0.004956
Saving checkpoint... 
Iteration: 603934643, states[0] = -94.999775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 617563039, states[0] = 4.817294, states[40]= 0.004606
Saving checkpoint... 
Iteration: 631140077, states[0] = -63.411517, states[40]= 0.000003
Saving checkpoint... 
Iteration: 644505424, states[0] = 25.328205, states[40]= 0.144641
Saving checkpoint... 
Iteration: 657651831, states[0] = -80.525100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 671161996, states[0] = -93.254484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 684527486, states[0] = 18.155786, states[40]= 0.006113
Saving checkpoint... 
Iteration: 697797713, states[0] = -94.943342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 711061680, states[0] = 5.432982, states[40]= 0.004637
Saving checkpoint... 
Iteration: 724782482, states[0] = -94.931020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 738401409, states[0] = -94.991868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 752020579, states[0] = 19.809926, states[40]= 0.008623
Saving checkpoint... 
Iteration: 765392078, states[0] = -94.989182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 778794567, states[0] = -94.940898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 792335623, states[0] = -94.966845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 805778507, states[0] = -94.927424, states[40]= 0.000000
Saving checkpoint... 
Iteration: 819274255, states[0] = -94.923466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 832743081, states[0] = -94.888544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 846066523, states[0] = 3.170774, states[40]= 0.004499
Saving checkpoint... 
Iteration: 859361423, states[0] = -94.978496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 872866722, states[0] = -94.980551, states[40]= 0.000000
Saving checkpoint... 
Iteration: 886236330, states[0] = -94.879350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 899944777, states[0] = -95.001505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 913361684, states[0] = -94.978563, states[40]= 0.000000
Saving checkpoint... 
Iteration: 926768488, states[0] = -94.917750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 940147527, states[0] = -73.381362, states[40]= 0.000000
Saving checkpoint... 
Iteration: 950977674, states[0] = -95.006628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 964361762, states[0] = -94.978558, states[40]= 0.000000
Saving checkpoint... 
Iteration: 977844741, states[0] = -94.971186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 991229501, states[0] = -94.869355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1004559982, states[0] = 6.184476, states[40]= 0.004670
Saving checkpoint... 
Iteration: 1017989070, states[0] = -95.008025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1031492430, states[0] = -95.008412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1044907887, states[0] = -94.993372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1058318535, states[0] = -94.957123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1071734260, states[0] = -94.876284, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1082169648, states[0] = -94.620860, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1096168762, states[0] = -94.574867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1109752581, states[0] = -94.900203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1123455801, states[0] = -95.003257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1137246726, states[0] = -94.893015, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1150978067, states[0] = -95.006540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1164933719, states[0] = -94.999195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1178944620, states[0] = -95.001280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1192462970, states[0] = -95.004348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1206077908, states[0] = -3.273855, states[40]= 0.003680
Saving checkpoint... 
Iteration: 1219611960, states[0] = -34.056436, states[40]= 0.000276
Saving checkpoint... 
Iteration: 1233551969, states[0] = 9.523209, states[40]= 0.004774
Saving checkpoint... 
Iteration: 1247164908, states[0] = -94.138221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1260747326, states[0] = -94.893683, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1274359579, states[0] = -94.977462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1287993358, states[0] = -95.008339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1301401159, states[0] = -94.991404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1314822365, states[0] = -94.959221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1328470308, states[0] = -95.005342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1342012318, states[0] = 21.098837, states[40]= 0.030019
Saving checkpoint... 
Iteration: 1355769784, states[0] = -94.918745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1365225480, states[0] = -94.862925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1378773884, states[0] = -94.922719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1392189569, states[0] = -94.796801, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1405687839, states[0] = -94.793031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1419090040, states[0] = -13.099403, states[40]= 0.001737
Saving checkpoint... 
Iteration: 1432565254, states[0] = 3.783118, states[40]= 0.004543
Saving checkpoint... 
Iteration: 1446041940, states[0] = 13.370340, states[40]= 0.004955
Saving checkpoint... 
Iteration: 1459299032, states[0] = -94.943785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1472487978, states[0] = -95.007574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1486076848, states[0] = -2.577794, states[40]= 0.003801
Saving checkpoint... 
Iteration: 1499570675, states[0] = 1.046881, states[40]= 0.004305
Saving checkpoint... 
Iteration: 1512934213, states[0] = 14.715622, states[40]= 0.006273
Saving checkpoint... 
Iteration: 1526270599, states[0] = -95.083003, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1539684190, states[0] = -22.951117, states[40]= 0.000804
Saving checkpoint... 
Iteration: 1553647445, states[0] = -95.227997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1567946912, states[0] = -94.929432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1581649660, states[0] = 6.388182, states[40]= 0.005370
Saving checkpoint... 
Iteration: 1595326454, states[0] = -95.212679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1609095898, states[0] = -95.165519, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1622832726, states[0] = -87.660873, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1636180389, states[0] = -95.268781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1649488163, states[0] = -28.392057, states[40]= 0.000509
Saving checkpoint... 
Iteration: 1663087706, states[0] = -95.151200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1676382180, states[0] = -95.270646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1689919121, states[0] = 19.854454, states[40]= 0.011226
Saving checkpoint... 
Iteration: 1703568313, states[0] = -95.107569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1717194123, states[0] = -95.278808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1730320145, states[0] = -95.207089, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1743516241, states[0] = -95.201412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1756843941, states[0] = 9.373901, states[40]= 0.005616
Saving checkpoint... 
Iteration: 1770309669, states[0] = 22.430308, states[40]= 0.055931
Saving checkpoint... 
Iteration: 1783757424, states[0] = -95.250408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1793275614, states[0] = -95.125123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1806718000, states[0] = -94.896479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1820212897, states[0] = -94.877672, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1833525135, states[0] = 18.520896, states[40]= 0.006561
Saving checkpoint... 
Iteration: 1847284570, states[0] = -94.948584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1856493750, states[0] = -95.020363, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1869905188, states[0] = -95.000326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1883549527, states[0] = 10.395500, states[40]= 0.004803
Saving checkpoint... 
Iteration: 1896821595, states[0] = -94.962007, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1910252123, states[0] = -94.901543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1923942450, states[0] = -95.001926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1937385182, states[0] = -94.987261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1950794075, states[0] = -94.940367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1964135684, states[0] = -58.419893, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1977490727, states[0] = -95.007814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1990945138, states[0] = -95.000961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2004374203, states[0] = -94.982581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2017715198, states[0] = -94.845605, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2031193755, states[0] = -94.805103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2044728031, states[0] = -94.866366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2058220907, states[0] = -94.855089, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2071559727, states[0] = 6.295657, states[40]= 0.004675
Saving checkpoint... 
Iteration: 2085090610, states[0] = -13.630220, states[40]= 0.001652
Saving checkpoint... 
Iteration: 2098508182, states[0] = 22.242430, states[40]= 0.080240
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.884331
 - CaMKt in component CaMK (millimolar): 0.006973
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.513123
 - nass in component intracellular_ions (millimolar): 6.513182
 - ki in component intracellular_ions (millimolar): 145.463846
 - kss in component intracellular_ions (millimolar): 145.463828
 - cansr in component intracellular_ions (millimolar): 1.311284
 - cajsr in component intracellular_ions (millimolar): 1.273582
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003625
 - hf in component INa (dimensionless): 0.879696
 - hs in component INa (dimensionless): 0.879692
 - j in component INa (dimensionless): 0.879665
 - hsp in component INa (dimensionless): 0.725259
 - jp in component INa (dimensionless): 0.879647
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.710184
 - hLp in component INaL (dimensionless): 0.453659
 - a in component Ito (dimensionless): 0.000624
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.624694
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.700793
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.940504
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999900
 - jca in component ICaL (dimensionless): 0.999980
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001592
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.311439
 - xs1 in component IKs (dimensionless): 0.232819
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997342
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
12:53:37 (4948): called boinc_finish(0)

</stderr_txt>
]]>


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