𝕏

Task 55370336

Name HuVeMOp_20240630012025727263_ORdGradInc_k_25-BASE_MID-conf_554_0
Workunit 26292670
Created 29 Jun 2024, 23:24:13 UTC
Sent 30 Jun 2024, 2:53:01 UTC
Report deadline 3 Jul 2024, 2:53:01 UTC
Received 30 Jun 2024, 13:54:22 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 226319
Run time 2 hours 40 min 51 sec
CPU time 2 hours 34 min 10 sec
Validate state Invalid
Credit 0.00
Device peak FLOPS 2.75 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.83 MB
Peak swap size 6.39 MB
Peak disk usage 0.33 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630012025727263_ORdGradInc_k_25-BASE_MID-conf_554.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630012025727263_ORdGradInc_k_25-BASE_MID-conf_554_0_r1068917652_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630012025727263_ORdGradInc_k_25-BASE_MID-conf_554_0_r1068917652_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 14
     * GNa in INa: 112.269982
     * GNaL_b in INaL: 0.006690
     * Gto_b in Ito: 0.081164
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030274
     * GKs_b in IKs: 0.001847
     * GK1_b in IK1: 0.157481
     * Gncx_b in INaCa_i: 0.000955
     * Pnak_b in INaK: 72.694179
     * GKb_b in IKb: 0.003764
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.048204
     * celltype in environment: 2.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 10120566, states[0] = 2.604314, states[40]= 0.000046
Saving checkpoint... 
Iteration: 19976664, states[0] = -86.946442, states[40]= 0.000002
Saving checkpoint... 
Iteration: 29906098, states[0] = -86.920446, states[40]= 0.000002
Saving checkpoint... 
Iteration: 39823838, states[0] = -86.811613, states[40]= 0.000001
Saving checkpoint... 
Iteration: 49765707, states[0] = -86.624814, states[40]= 0.000001
Saving checkpoint... 
Iteration: 59701585, states[0] = -78.161732, states[40]= 0.000002
Saving checkpoint... 
Iteration: 69586104, states[0] = 13.871272, states[40]= 0.000006
Saving checkpoint... 
Iteration: 79567566, states[0] = 21.429992, states[40]= 0.000001
Saving checkpoint... 
Iteration: 89443134, states[0] = -87.016414, states[40]= 0.000002
Saving checkpoint... 
Iteration: 99331388, states[0] = -86.883406, states[40]= 0.000001
Saving checkpoint... 
Iteration: 109228009, states[0] = -86.437840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 118500973, states[0] = 37.536332, states[40]= 1.350050
Saving checkpoint... 
Iteration: 128352017, states[0] = -86.929414, states[40]= 0.000002
Saving checkpoint... 
Iteration: 137859609, states[0] = -86.942712, states[40]= 0.000002
Saving checkpoint... 
Iteration: 147689038, states[0] = -65.862480, states[40]= 0.000013
Saving checkpoint... 
Iteration: 157588882, states[0] = 12.017672, states[40]= 0.000010
Saving checkpoint... 
Iteration: 167567264, states[0] = 21.209097, states[40]= 0.000001
Saving checkpoint... 
Iteration: 177542629, states[0] = 29.411372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 187134845, states[0] = -15.804765, states[40]= 0.000186
Saving checkpoint... 
Iteration: 197005399, states[0] = 21.816815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 206884447, states[0] = -86.976684, states[40]= 0.000002
Saving checkpoint... 
Iteration: 216791551, states[0] = -86.779326, states[40]= 0.000001
Saving checkpoint... 
Iteration: 226737769, states[0] = -86.511460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 236684279, states[0] = -60.128144, states[40]= 0.000028
Saving checkpoint... 
Iteration: 246591738, states[0] = 10.663769, states[40]= 0.000014
Saving checkpoint... 
Iteration: 256445426, states[0] = -87.026583, states[40]= 0.000002
Saving checkpoint... 
Iteration: 265854079, states[0] = -86.931488, states[40]= 0.000002
Saving checkpoint... 
Iteration: 275754351, states[0] = -86.610786, states[40]= 0.000001
Saving checkpoint... 
Iteration: 285658120, states[0] = -34.078761, states[40]= 0.000479
Saving checkpoint... 
Iteration: 295593210, states[0] = 9.978907, states[40]= 0.000017
Saving checkpoint... 
Iteration: 305226805, states[0] = -86.428852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 315123249, states[0] = -6.651578, states[40]= 0.000164
Saving checkpoint... 
Iteration: 325056695, states[0] = 25.109647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 334992442, states[0] = -87.044455, states[40]= 0.000002
Saving checkpoint... 
Iteration: 344209730, states[0] = -86.083248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 353685773, states[0] = -61.975248, states[40]= 0.000022
Saving checkpoint... 
Iteration: 363208053, states[0] = -85.916709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 372663183, states[0] = -38.492279, states[40]= 0.000351
Saving checkpoint... 
Iteration: 382181595, states[0] = -57.004525, states[40]= 0.000043
Saving checkpoint... 
Iteration: 391621423, states[0] = -5.346520, states[40]= 0.000155
Saving checkpoint... 
Iteration: 400909675, states[0] = -86.993373, states[40]= 0.000002
Saving checkpoint... 
Iteration: 410090203, states[0] = 11.370841, states[40]= 0.000012
Saving checkpoint... 
Iteration: 419268882, states[0] = -86.677497, states[40]= 0.000001
Saving checkpoint... 
Iteration: 428751253, states[0] = -86.585528, states[40]= 0.000001
Saving checkpoint... 
Iteration: 438139014, states[0] = -19.198579, states[40]= 0.000236
Saving checkpoint... 
Iteration: 447553690, states[0] = 26.132483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 457053219, states[0] = 26.288173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 466483908, states[0] = -87.034824, states[40]= 0.000002
Saving checkpoint... 
Iteration: 475760252, states[0] = -86.632266, states[40]= 0.000001
Saving checkpoint... 
Iteration: 485257111, states[0] = -86.615226, states[40]= 0.000001
Saving checkpoint... 
Iteration: 494773336, states[0] = -86.693812, states[40]= 0.000001
Saving checkpoint... 
Iteration: 504245466, states[0] = -86.547161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 513758529, states[0] = -86.621339, states[40]= 0.000001
Saving checkpoint... 
Iteration: 523139845, states[0] = -19.841808, states[40]= 0.000253
Saving checkpoint... 
Iteration: 532673398, states[0] = -48.256488, states[40]= 0.000129
Saving checkpoint... 
Iteration: 541798629, states[0] = -86.787190, states[40]= 0.000001
Saving checkpoint... 
Iteration: 551135797, states[0] = -16.619784, states[40]= 0.000192
Saving checkpoint... 
Iteration: 560668306, states[0] = -43.232437, states[40]= 0.000224
Saving checkpoint... 
Iteration: 570168450, states[0] = -43.369431, states[40]= 0.000221
Saving checkpoint... 
Iteration: 579632375, states[0] = -13.819178, states[40]= 0.000177
Saving checkpoint... 
Iteration: 589164260, states[0] = -39.448041, states[40]= 0.000322
Saving checkpoint... 
Iteration: 598679044, states[0] = -54.154991, states[40]= 0.000062
Saving checkpoint... 
Iteration: 608220279, states[0] = -86.356967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 617730299, states[0] = -86.439162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 627228900, states[0] = -86.428267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 636654220, states[0] = -30.833908, states[40]= 0.000540
Saving checkpoint... 
Iteration: 646146428, states[0] = -24.815663, states[40]= 0.000447
Saving checkpoint... 
Iteration: 655499494, states[0] = -87.030924, states[40]= 0.000002
Saving checkpoint... 
Iteration: 665019908, states[0] = 31.926576, states[40]= 0.000000
Saving checkpoint... 
Iteration: 674511758, states[0] = 29.291709, states[40]= -0.000000
Saving checkpoint... 
Iteration: 683478500, states[0] = -87.021922, states[40]= 0.000002
Saving checkpoint... 
Iteration: 692904678, states[0] = -86.974307, states[40]= 0.000002
Saving checkpoint... 
Iteration: 701973636, states[0] = -87.018961, states[40]= 0.000002
Saving checkpoint... 
Iteration: 711511479, states[0] = 29.119921, states[40]= 0.000000
Saving checkpoint... 
Iteration: 721004533, states[0] = 19.526802, states[40]= 0.000006
Saving checkpoint... 
Iteration: 730454160, states[0] = -87.008107, states[40]= 0.000002
Saving checkpoint... 
Iteration: 739950607, states[0] = -87.005679, states[40]= 0.000002
Saving checkpoint... 
Iteration: 749156480, states[0] = -32.671420, states[40]= 0.000510
Saving checkpoint... 
Iteration: 758513057, states[0] = 30.003140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 768039877, states[0] = 30.075560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 777538856, states[0] = 30.305141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 787057881, states[0] = 24.702966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 796518907, states[0] = 31.790504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 805995255, states[0] = -87.022083, states[40]= 0.000002
Saving checkpoint... 
Iteration: 815485804, states[0] = -87.018245, states[40]= 0.000002
Saving checkpoint... 
Iteration: 824434780, states[0] = -86.991755, states[40]= 0.000002
Saving checkpoint... 
Iteration: 833813465, states[0] = -86.816328, states[40]= 0.000001
Saving checkpoint... 
Iteration: 843241844, states[0] = -86.506976, states[40]= 0.000000
Saving checkpoint... 
Iteration: 852696913, states[0] = -78.214975, states[40]= 0.000002
Saving checkpoint... 
Iteration: 862132744, states[0] = -14.100728, states[40]= 0.000177
Saving checkpoint... 
Iteration: 871685224, states[0] = -61.212413, states[40]= 0.000024
Saving checkpoint... 
Iteration: 881211316, states[0] = -86.149002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 890658086, states[0] = -34.003399, states[40]= 0.000477
Saving checkpoint... 
Iteration: 900057422, states[0] = 24.866879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 909582096, states[0] = 15.019229, states[40]= 0.000005
Saving checkpoint... 
Iteration: 919110547, states[0] = 1.352233, states[40]= 0.000081
Saving checkpoint... 
Iteration: 928625657, states[0] = -8.411767, states[40]= 0.000170
Saving checkpoint... 
Iteration: 938094126, states[0] = 9.567032, states[40]= 0.000018
Saving checkpoint... 
Iteration: 947540810, states[0] = 29.860875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 957039826, states[0] = 30.091144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 965956437, states[0] = -86.997648, states[40]= 0.000002
Saving checkpoint... 
Iteration: 975167673, states[0] = -42.587912, states[40]= 0.000238
Saving checkpoint... 
Iteration: 984704008, states[0] = -84.877747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 994154042, states[0] = -30.662234, states[40]= 0.000540
Saving checkpoint... 
Iteration: 1003552371, states[0] = 26.575873, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1013034375, states[0] = 31.188333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1022501779, states[0] = 29.516015, states[40]= 1.858142
Saving checkpoint... 
Iteration: 1032005936, states[0] = 23.036291, states[40]= -0.000000
Saving checkpoint... 
Iteration: 1041295891, states[0] = -86.753024, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1050761965, states[0] = -86.611813, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1060257827, states[0] = -86.589802, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1069727581, states[0] = -86.395490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1079232204, states[0] = -86.429298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1088724932, states[0] = -86.373592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1098212281, states[0] = -86.179148, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1107100686, states[0] = 6.432626, states[40]= 0.000034
Saving checkpoint... 
Iteration: 1116485383, states[0] = -87.003170, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1125953068, states[0] = -86.987891, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1135423245, states[0] = -86.968061, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1144955484, states[0] = -86.988269, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1154442852, states[0] = -86.980570, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1163872461, states[0] = -86.914392, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1173404959, states[0] = -86.950680, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1182902126, states[0] = -86.947506, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1192309335, states[0] = -86.786898, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1201667690, states[0] = -42.581633, states[40]= 0.000238
Saving checkpoint... 
Iteration: 1211170223, states[0] = -45.022412, states[40]= 0.000184
Saving checkpoint... 
Iteration: 1220674311, states[0] = -49.109499, states[40]= 0.000116
Saving checkpoint... 
Iteration: 1230147107, states[0] = -25.281985, states[40]= 0.000462
Saving checkpoint... 
Iteration: 1239514320, states[0] = 30.572645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1248308299, states[0] = -86.781137, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1257558016, states[0] = 24.664554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1267011447, states[0] = 29.108704, states[40]= -0.000000
Saving checkpoint... 
Iteration: 1276486977, states[0] = -86.995847, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1285951724, states[0] = -86.979225, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1295468992, states[0] = -86.987475, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1304669131, states[0] = -43.951497, states[40]= 0.000206
Saving checkpoint... 
Iteration: 1314096728, states[0] = 8.348749, states[40]= 0.000023
Saving checkpoint... 
Iteration: 1323542941, states[0] = 29.340442, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1333077308, states[0] = 17.096008, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1342543929, states[0] = 29.082752, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1352045127, states[0] = 28.759507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1361535153, states[0] = 31.059109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1370945130, states[0] = -86.971211, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1380392933, states[0] = -86.928317, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1389280150, states[0] = -86.677385, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1398750509, states[0] = -86.531722, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1408209794, states[0] = -86.020175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1417715291, states[0] = -86.245871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1427187498, states[0] = -64.019390, states[40]= 0.000016
Saving checkpoint... 
Iteration: 1436674622, states[0] = -49.404127, states[40]= 0.000112
Saving checkpoint... 
Iteration: 1446143051, states[0] = -22.226991, states[40]= 0.000335
Saving checkpoint... 
Iteration: 1455313939, states[0] = -86.786421, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1464847069, states[0] = -86.859490, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1474314764, states[0] = -86.787669, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1483434718, states[0] = -86.959016, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1493840333, states[0] = -86.845333, states[40]= 0.000002
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.865165
 - CaMKt in component CaMK (millimolar): 0.024809
 - cass in component intracellular_ions (millimolar): 0.000092
 - nai in component intracellular_ions (millimolar): 7.915191
 - nass in component intracellular_ions (millimolar): 7.915339
 - ki in component intracellular_ions (millimolar): 143.531958
 - kss in component intracellular_ions (millimolar): 143.531920
 - cansr in component intracellular_ions (millimolar): 2.013427
 - cajsr in component intracellular_ions (millimolar): 1.945418
 - cai in component intracellular_ions (millimolar): 0.000095
 - m in component INa (dimensionless): 0.008131
 - hf in component INa (dimensionless): 0.661932
 - hs in component INa (dimensionless): 0.661901
 - j in component INa (dimensionless): 0.661725
 - hsp in component INa (dimensionless): 0.414047
 - jp in component INa (dimensionless): 0.661599
 - mL in component INaL (dimensionless): 0.000228
 - hL in component INaL (dimensionless): 0.456643
 - hLp in component INaL (dimensionless): 0.221123
 - a in component Ito (dimensionless): 0.001072
 - iF in component Ito (dimensionless): 0.999468
 - iS in component Ito (dimensionless): 0.528615
 - ap in component Ito (dimensionless): 0.000546
 - iFp in component Ito (dimensionless): 0.999468
 - iSp in component Ito (dimensionless): 0.571760
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.872554
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999569
 - jca in component ICaL (dimensionless): 0.999933
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003685
 - xrf in component IKr (dimensionless): 0.000010
 - xrs in component IKr (dimensionless): 0.514372
 - xs1 in component IKs (dimensionless): 0.340986
 - xs2 in component IKs (dimensionless): 0.000216
 - xk1 in component IK1 (dimensionless): 0.997016
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000002
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000002
05:53:54 (13588): called boinc_finish(0)

</stderr_txt>
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