𝕏

Task 55368120

Name HuVeMOp_20240630012025727263_ORdGradInc_k_25-Drouin_ENDO_5000-conf_431_0
Workunit 26291562
Created 29 Jun 2024, 23:22:55 UTC
Sent 30 Jun 2024, 2:34:27 UTC
Report deadline 3 Jul 2024, 2:34:27 UTC
Received 1 Jul 2024, 16:28:39 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241050
Run time 3 hours 2 min 11 sec
CPU time 1 hours 29 min 41 sec
Validate state Valid
Credit 45.20
Device peak FLOPS 6.58 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.38 MB
Peak swap size 3.69 MB
Peak disk usage 0.04 MB

Stderr output

<core_client_version>7.16.16</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630012025727263_ORdGradInc_k_25-Drouin_ENDO_5000-conf_431.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630012025727263_ORdGradInc_k_25-Drouin_ENDO_5000-conf_431_0_r156501087_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630012025727263_ORdGradInc_k_25-Drouin_ENDO_5000-conf_431_0_r156501087_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 108.889707
     * GNaL_b in INaL: 0.005803
     * Gto_b in Ito: 0.081799
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033055
     * GKs_b in IKs: 0.001890
     * GK1_b in IK1: 0.176353
     * Gncx_b in INaCa_i: 0.000957
     * Pnak_b in INaK: 72.518232
     * GKb_b in IKb: 0.003811
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.052736
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 600.000000
     * CL_0 in membrane: 5000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 9736355, states[0] = -94.198920, states[40]= 0.000000
Saving checkpoint... 
Iteration: 17562874, states[0] = 19.346813, states[40]= 0.001792
Saving checkpoint... 
Iteration: 25849523, states[0] = -94.122327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 33332321, states[0] = -94.104963, states[40]= 0.000000
Saving checkpoint... 
Iteration: 41828294, states[0] = -94.069611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 50512760, states[0] = -94.058869, states[40]= 0.000000
Saving checkpoint... 
Iteration: 58621001, states[0] = -94.076027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 67283872, states[0] = -94.051914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 75126070, states[0] = -15.767964, states[40]= 0.001753
Saving checkpoint... 
Iteration: 83531609, states[0] = -94.074908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 91772639, states[0] = -94.055687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 100030976, states[0] = 29.932812, states[40]= 0.000209
Saving checkpoint... 
Iteration: 108351319, states[0] = -94.078902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 116890124, states[0] = -94.052949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 124991365, states[0] = -94.046386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 132471492, states[0] = -94.046412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 139895404, states[0] = -94.046930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 147715738, states[0] = -93.263217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 156093416, states[0] = -94.070820, states[40]= 0.000000
Saving checkpoint... 
Iteration: 164507096, states[0] = -94.050728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 172154341, states[0] = -94.048954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 180471217, states[0] = -94.031646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 188565044, states[0] = -94.071554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 197082200, states[0] = -94.049641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 204707744, states[0] = -94.048239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 212500655, states[0] = 41.628620, states[40]= 0.052071
Saving checkpoint... 
Iteration: 219962817, states[0] = -94.045885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 228572299, states[0] = -94.071175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 236573276, states[0] = -94.057478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 244838727, states[0] = -94.046868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 252943640, states[0] = -94.015196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 261071745, states[0] = -94.071116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 268659791, states[0] = -94.068232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 277813011, states[0] = -93.839899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 286093056, states[0] = -94.070361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 295457495, states[0] = -94.023783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 303759565, states[0] = -94.065111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 312092726, states[0] = -94.049238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 320650849, states[0] = -94.074561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 330377118, states[0] = -93.952956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 338042591, states[0] = -94.057845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 346803459, states[0] = -94.053091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 354678344, states[0] = -94.048214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 362168575, states[0] = -94.048304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 369910987, states[0] = -94.045998, states[40]= 0.000000
Saving checkpoint... 
Iteration: 379313394, states[0] = -94.052876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 387177374, states[0] = -94.048165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 395190557, states[0] = -70.286337, states[40]= 0.000008
Saving checkpoint... 
Iteration: 402914479, states[0] = -93.992460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 410463804, states[0] = -94.027160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 418040163, states[0] = -94.057066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 426743748, states[0] = -94.053924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 434985121, states[0] = -94.045283, states[40]= 0.000000
Saving checkpoint... 
Iteration: 441758215, states[0] = -94.053654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 450799584, states[0] = -94.078107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 458588608, states[0] = -94.070193, states[40]= 0.000000
Saving checkpoint... 
Iteration: 466592763, states[0] = -94.056643, states[40]= 0.000000
Saving checkpoint... 
Iteration: 474464317, states[0] = -94.050532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 482041846, states[0] = -94.049533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 491116708, states[0] = -94.069212, states[40]= 0.000000
Saving checkpoint... 
Iteration: 498855631, states[0] = -94.062083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 506907050, states[0] = -94.051256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 516494507, states[0] = -94.058651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 524055295, states[0] = -94.057312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 531825871, states[0] = -94.052408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 540385099, states[0] = -93.962284, states[40]= 0.000000
Saving checkpoint... 
Iteration: 548429091, states[0] = -94.075177, states[40]= 0.000000
Saving checkpoint... 
Iteration: 556218271, states[0] = -94.065887, states[40]= 0.000000
Saving checkpoint... 
Iteration: 564330083, states[0] = -94.052285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 573632179, states[0] = -94.068562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 582313678, states[0] = -94.046470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 589769366, states[0] = -94.046874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 598144195, states[0] = -94.073525, states[40]= 0.000000
Saving checkpoint... 
Iteration: 606777374, states[0] = -94.053043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 615185557, states[0] = -65.002189, states[40]= 0.000020
Saving checkpoint... 
Iteration: 622751929, states[0] = -93.639294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 630563988, states[0] = -94.062294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 638702763, states[0] = -94.066214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 646997493, states[0] = -94.049791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 656449068, states[0] = -94.059454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 665057421, states[0] = 21.802342, states[40]= 0.000715
Saving checkpoint... 
Iteration: 674162270, states[0] = -94.054926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 682541308, states[0] = 27.180464, states[40]= 0.000297
Saving checkpoint... 
Iteration: 690652847, states[0] = -94.074050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 699858975, states[0] = -94.045852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 709402039, states[0] = -94.050964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 718828278, states[0] = -94.062424, states[40]= 0.000000
Saving checkpoint... 
Iteration: 726011500, states[0] = -94.072265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 734512618, states[0] = -94.049443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 742289185, states[0] = -94.046412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 750166830, states[0] = -48.545225, states[40]= 0.000271
Saving checkpoint... 
Iteration: 759282023, states[0] = -94.052694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 767455911, states[0] = -94.044917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 775667470, states[0] = -94.074897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 783724384, states[0] = -94.065295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 792881745, states[0] = -93.957842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 801156173, states[0] = -94.067384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 809239939, states[0] = -94.053304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 816687656, states[0] = -94.054206, states[40]= 0.000000
Saving checkpoint... 
Iteration: 825001236, states[0] = 49.961630, states[40]= 0.441943
Saving checkpoint... 
Iteration: 832463396, states[0] = -94.044741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 840788662, states[0] = -94.077488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 848783251, states[0] = -94.063448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 857135572, states[0] = -94.047774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 864884756, states[0] = -94.045332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 872813184, states[0] = -93.839225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 879982395, states[0] = -94.044506, states[40]= 0.000000
Saving checkpoint... 
Iteration: 888818520, states[0] = -94.062387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 899339653, states[0] = -94.051539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 906384048, states[0] = -94.060614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 914972906, states[0] = -94.044518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 923454437, states[0] = -94.073741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 930851345, states[0] = -94.076475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 938701320, states[0] = -94.065721, states[40]= 0.000000
Saving checkpoint... 
Iteration: 946114657, states[0] = -94.068466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 954453564, states[0] = -94.049815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 963743736, states[0] = -94.064393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 972399131, states[0] = -94.045017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 980496063, states[0] = -94.041476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 988687866, states[0] = -94.066049, states[40]= 0.000000
Saving checkpoint... 
Iteration: 997667683, states[0] = -49.262539, states[40]= 0.000245
Saving checkpoint... 
Iteration: 1004795632, states[0] = -94.045881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1011849647, states[0] = -94.051187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1020738436, states[0] = -94.076982, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1028793354, states[0] = -94.062839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1036983429, states[0] = -94.049273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1044496740, states[0] = -94.049089, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1052630144, states[0] = -19.076364, states[40]= 0.001695
Saving checkpoint... 
Iteration: 1060056331, states[0] = 22.192608, states[40]= 0.000675
Saving checkpoint... 
Iteration: 1068345991, states[0] = -94.076335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1077159948, states[0] = -94.047114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1085080250, states[0] = 12.883347, states[40]= 0.002111
Saving checkpoint... 
Iteration: 1093813430, states[0] = -94.062161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1101650427, states[0] = -94.054383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1110477358, states[0] = -94.032927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1119269862, states[0] = -94.052248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1127084014, states[0] = -94.047875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1134772889, states[0] = -94.045864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1142972016, states[0] = -94.030209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1151107683, states[0] = -94.068327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1158944996, states[0] = -94.058652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1167036920, states[0] = -94.048366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1175750891, states[0] = -94.076846, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1183521932, states[0] = -94.071104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1190958723, states[0] = -94.073130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1199605312, states[0] = -94.047500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1207437864, states[0] = -94.044274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1215740350, states[0] = -94.076660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1225552044, states[0] = -94.058587, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1234334217, states[0] = -94.051022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1242603082, states[0] = 1.670628, states[40]= 0.003864
Saving checkpoint... 
Iteration: 1251215975, states[0] = -94.064713, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1260013478, states[0] = 31.493882, states[40]= 0.017453
Saving checkpoint... 
Iteration: 1268854247, states[0] = -94.060742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1277480509, states[0] = -94.043809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1285944727, states[0] = -94.073391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1294569416, states[0] = -94.047747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1303718499, states[0] = -94.064543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1312813716, states[0] = -93.839695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1320930884, states[0] = -94.073744, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1329705900, states[0] = -94.046179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1338346961, states[0] = -94.075834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1346674444, states[0] = -94.053498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1355383086, states[0] = -93.958440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1364444475, states[0] = -94.049203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1372775488, states[0] = -93.728908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1380774431, states[0] = -94.076568, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1389916285, states[0] = -94.044125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1398538749, states[0] = -94.070163, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1406584924, states[0] = -94.055119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1415793812, states[0] = -94.076428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1424231389, states[0] = -94.052348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1432489888, states[0] = -94.043458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1440468039, states[0] = -94.027607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1448878994, states[0] = -94.059773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1457859328, states[0] = -93.926356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1465894643, states[0] = -94.074500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1473701225, states[0] = -94.064767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1484112668, states[0] = -94.054425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1493293946, states[0] = -94.076289, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.919234
 - CaMKt in component CaMK (millimolar): 0.001558
 - cass in component intracellular_ions (millimolar): 0.000101
 - nai in component intracellular_ions (millimolar): 6.680799
 - nass in component intracellular_ions (millimolar): 6.680921
 - ki in component intracellular_ions (millimolar): 145.183873
 - kss in component intracellular_ions (millimolar): 145.183863
 - cansr in component intracellular_ions (millimolar): 1.824185
 - cajsr in component intracellular_ions (millimolar): 1.824046
 - cai in component intracellular_ions (millimolar): 0.000105
 - m in component INa (dimensionless): 0.003996
 - hf in component INa (dimensionless): 0.861877
 - hs in component INa (dimensionless): 0.861877
 - j in component INa (dimensionless): 0.861879
 - hsp in component INa (dimensionless): 0.692587
 - jp in component INa (dimensionless): 0.861880
 - mL in component INaL (dimensionless): 0.000060
 - hL in component INaL (dimensionless): 0.702505
 - hLp in component INaL (dimensionless): 0.507774
 - a in component Ito (dimensionless): 0.000666
 - iF in component Ito (dimensionless): 0.999845
 - iS in component Ito (dimensionless): 0.997634
 - ap in component Ito (dimensionless): 0.000339
 - iFp in component Ito (dimensionless): 0.999845
 - iSp in component Ito (dimensionless): 0.999190
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998739
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005318
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.002076
 - xs1 in component IKs (dimensionless): 0.023819
 - xs2 in component IKs (dimensionless): 0.000098
 - xk1 in component IK1 (dimensionless): 0.997583
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
16:51:47 (29620): called boinc_finish(0)

</stderr_txt>
]]>


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