𝕏

Task 55364708

Name HuVeMOp_20240630012025727263_ORdGradInc_k_25-Pueyo_APDR-conf_908_1
Workunit 26289859
Created 29 Jun 2024, 23:21:02 UTC
Sent 30 Jun 2024, 2:00:32 UTC
Report deadline 3 Jul 2024, 11:36:32 UTC
Received 30 Jun 2024, 4:31:57 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241023
Run time 2 hours 27 min 24 sec
CPU time 2 hours 25 min 16 sec
Validate state Valid
Credit 59.94
Device peak FLOPS 1.00 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.25 MB
Peak swap size 3.82 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630012025727263_ORdGradInc_k_25-Pueyo_APDR-conf_908.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630012025727263_ORdGradInc_k_25-Pueyo_APDR-conf_908_1_r27054324_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630012025727263_ORdGradInc_k_25-Pueyo_APDR-conf_908_1_r27054324_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 112.974420
     * GNaL_b in INaL: 0.006312
     * Gto_b in Ito: 0.085005
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.031094
     * GKs_b in IKs: 0.001872
     * GK1_b in IK1: 0.154699
     * Gncx_b in INaCa_i: 0.000976
     * Pnak_b in INaK: 66.561455
     * GKb_b in IKb: 0.003722
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.028762
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 15427705, states[0] = -95.048285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 30649464, states[0] = -70.101076, states[40]= 0.000001
Saving checkpoint... 
Iteration: 45450281, states[0] = -95.014407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 60786987, states[0] = -94.926960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 76184661, states[0] = -94.738686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 91545335, states[0] = 14.022757, states[40]= 0.005094
Saving checkpoint... 
Iteration: 106863787, states[0] = -94.968492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 122217062, states[0] = -94.816152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 137359562, states[0] = -94.964302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 152741509, states[0] = -94.857171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 168092374, states[0] = -10.253860, states[40]= 0.002286
Saving checkpoint... 
Iteration: 183390815, states[0] = -94.976007, states[40]= 0.000000
Saving checkpoint... 
Iteration: 198864595, states[0] = -94.965303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 214371114, states[0] = -94.968067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 229750198, states[0] = -94.869056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 245149499, states[0] = -66.959845, states[40]= 0.000002
Saving checkpoint... 
Iteration: 260174721, states[0] = -94.368602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 275154896, states[0] = -74.328255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 289926707, states[0] = -94.986347, states[40]= 0.000000
Saving checkpoint... 
Iteration: 304302766, states[0] = -94.926538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 318499456, states[0] = -94.999693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 332783475, states[0] = -94.908838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 347592386, states[0] = -10.233502, states[40]= 0.002290
Saving checkpoint... 
Iteration: 362197170, states[0] = -94.771841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 377032445, states[0] = 18.503323, states[40]= 0.005797
Saving checkpoint... 
Iteration: 391598681, states[0] = -15.839460, states[40]= 0.001365
Saving checkpoint... 
Iteration: 406392655, states[0] = -94.976090, states[40]= 0.000000
Saving checkpoint... 
Iteration: 421227203, states[0] = -94.832268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 436019737, states[0] = 21.710176, states[40]= 0.009977
Saving checkpoint... 
Iteration: 450331570, states[0] = -94.947222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 464508268, states[0] = 24.332841, states[40]= 0.080870
Saving checkpoint... 
Iteration: 478828785, states[0] = -94.945440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 492904906, states[0] = -94.980065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 507088546, states[0] = -7.102981, states[40]= 0.002955
Saving checkpoint... 
Iteration: 521346315, states[0] = -94.955751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 535626171, states[0] = -41.543790, states[40]= 0.000110
Saving checkpoint... 
Iteration: 549886840, states[0] = -94.973913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 564028583, states[0] = 19.633565, states[40]= 0.006309
Saving checkpoint... 
Iteration: 578187126, states[0] = -94.741029, states[40]= 0.000000
Saving checkpoint... 
Iteration: 592689942, states[0] = -94.752335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 607508205, states[0] = 24.373374, states[40]= 0.082060
Saving checkpoint... 
Iteration: 622589418, states[0] = -7.787531, states[40]= 0.002807
Saving checkpoint... 
Iteration: 637397143, states[0] = -94.977469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 652610590, states[0] = -26.809180, states[40]= 0.000655
Saving checkpoint... 
Iteration: 667558859, states[0] = 8.905752, states[40]= 0.004905
Saving checkpoint... 
Iteration: 682404090, states[0] = -94.979687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 697294594, states[0] = -94.919197, states[40]= 0.000000
Saving checkpoint... 
Iteration: 711935383, states[0] = -94.988164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 726876998, states[0] = -94.970002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 741463524, states[0] = -94.993932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 756213160, states[0] = -94.805590, states[40]= 0.000000
Saving checkpoint... 
Iteration: 771285338, states[0] = -94.910405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 786338819, states[0] = -94.951371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 801256239, states[0] = -94.876862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 816076824, states[0] = 0.556196, states[40]= 0.004334
Saving checkpoint... 
Iteration: 831125206, states[0] = -40.591447, states[40]= 0.000127
Saving checkpoint... 
Iteration: 846070355, states[0] = 3.862879, states[40]= 0.004658
Saving checkpoint... 
Iteration: 860887063, states[0] = -94.973791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 875530341, states[0] = 19.133443, states[40]= 0.006045
Saving checkpoint... 
Iteration: 890420602, states[0] = -94.984341, states[40]= 0.000000
Saving checkpoint... 
Iteration: 904890962, states[0] = -94.975168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 919356761, states[0] = -94.960868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 933838615, states[0] = -94.951155, states[40]= 0.000000
Saving checkpoint... 
Iteration: 948457246, states[0] = -94.992634, states[40]= 0.000000
Saving checkpoint... 
Iteration: 963060896, states[0] = 8.066691, states[40]= 0.004878
Saving checkpoint... 
Iteration: 977758496, states[0] = -94.879717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 992661244, states[0] = -84.514924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1007972569, states[0] = -94.995317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1023187033, states[0] = -94.740276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1038177706, states[0] = -94.581854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1052580927, states[0] = -1.825939, states[40]= 0.003992
Saving checkpoint... 
Iteration: 1067221415, states[0] = -94.821320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1081728080, states[0] = -94.833379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1096342475, states[0] = -94.953257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1110861011, states[0] = -94.962781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1125220610, states[0] = -94.819776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1140088452, states[0] = -7.029867, states[40]= 0.002971
Saving checkpoint... 
Iteration: 1154688594, states[0] = -94.747065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1169161266, states[0] = -84.549642, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1183669043, states[0] = -92.914679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1197723300, states[0] = -94.824720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1211773909, states[0] = -94.898121, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1225525048, states[0] = 20.557436, states[40]= 0.007103
Saving checkpoint... 
Iteration: 1239948568, states[0] = -94.990720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1254464025, states[0] = -94.993687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1269121893, states[0] = -37.380102, states[40]= 0.000201
Saving checkpoint... 
Iteration: 1284004463, states[0] = 30.604189, states[40]= 0.156457
Saving checkpoint... 
Iteration: 1299021926, states[0] = 21.271159, states[40]= 0.008384
Saving checkpoint... 
Iteration: 1314202798, states[0] = -94.783732, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1329309120, states[0] = -94.930962, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1344245466, states[0] = -94.861348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1358954785, states[0] = -94.991891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1373851060, states[0] = -94.957702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1388991056, states[0] = -94.997867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1403400686, states[0] = -94.978132, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1418034163, states[0] = 17.966394, states[40]= 0.005635
Saving checkpoint... 
Iteration: 1432568094, states[0] = 4.923260, states[40]= 0.004730
Saving checkpoint... 
Iteration: 1447328553, states[0] = -94.944656, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1462204516, states[0] = -94.787314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1476775237, states[0] = -94.899414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1491714755, states[0] = -94.808267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1506641096, states[0] = 13.569116, states[40]= 0.006027
Saving checkpoint... 
Iteration: 1521542653, states[0] = -95.200373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1536270366, states[0] = -95.245174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1551093396, states[0] = -27.469248, states[40]= 0.000608
Saving checkpoint... 
Iteration: 1565827275, states[0] = -67.301511, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1580739430, states[0] = 13.596509, states[40]= 0.006167
Saving checkpoint... 
Iteration: 1595467967, states[0] = -2.742754, states[40]= 0.004338
Saving checkpoint... 
Iteration: 1609849721, states[0] = 8.437020, states[40]= 0.005672
Saving checkpoint... 
Iteration: 1624037356, states[0] = -84.496905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1638256983, states[0] = -95.256574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1652538833, states[0] = -87.012490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1666952741, states[0] = -94.876908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1681471921, states[0] = -95.272418, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1696228999, states[0] = 18.079730, states[40]= 0.007295
Saving checkpoint... 
Iteration: 1711076199, states[0] = -95.114927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1725812414, states[0] = -95.194374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1740651424, states[0] = 7.492319, states[40]= 0.005604
Saving checkpoint... 
Iteration: 1755449029, states[0] = -94.509006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1770446435, states[0] = -93.883646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1784715251, states[0] = 22.633911, states[40]= 0.019583
Saving checkpoint... 
Iteration: 1799391432, states[0] = -95.288968, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1814501563, states[0] = 48.776448, states[40]= 0.071865
Saving checkpoint... 
Iteration: 1829485459, states[0] = -95.029433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1844514564, states[0] = 22.424380, states[40]= 0.020088
Saving checkpoint... 
Iteration: 1859595328, states[0] = -13.493399, states[40]= 0.001701
Saving checkpoint... 
Iteration: 1874399204, states[0] = -94.986248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1889524602, states[0] = 20.608334, states[40]= 0.007230
Saving checkpoint... 
Iteration: 1904336104, states[0] = -94.952776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1918930957, states[0] = -94.988745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1933901583, states[0] = -94.979634, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1948969440, states[0] = -94.995169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1964000794, states[0] = 46.397954, states[40]= 0.013029
Saving checkpoint... 
Iteration: 1979047520, states[0] = 13.296708, states[40]= 0.005047
Saving checkpoint... 
Iteration: 1994010137, states[0] = 23.482987, states[40]= 0.052073
Saving checkpoint... 
Iteration: 2009181921, states[0] = -94.695732, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2024041250, states[0] = 15.577810, states[40]= 0.005216
Saving checkpoint... 
Iteration: 2039013617, states[0] = 22.728831, states[40]= 0.024231
Saving checkpoint... 
Iteration: 2053921783, states[0] = -94.983889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2068673828, states[0] = -94.258966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2083580174, states[0] = -1.368395, states[40]= 0.004065
Saving checkpoint... 
Iteration: 2098608929, states[0] = -25.277779, states[40]= 0.000727
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.874421
 - CaMKt in component CaMK (millimolar): 0.007165
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.677285
 - nass in component intracellular_ions (millimolar): 6.677346
 - ki in component intracellular_ions (millimolar): 145.297813
 - kss in component intracellular_ions (millimolar): 145.297794
 - cansr in component intracellular_ions (millimolar): 1.322945
 - cajsr in component intracellular_ions (millimolar): 1.284482
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003629
 - hf in component INa (dimensionless): 0.879524
 - hs in component INa (dimensionless): 0.879519
 - j in component INa (dimensionless): 0.879487
 - hsp in component INa (dimensionless): 0.724930
 - jp in component INa (dimensionless): 0.879466
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.708151
 - hLp in component INaL (dimensionless): 0.448103
 - a in component Ito (dimensionless): 0.000625
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.617211
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.691084
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.932348
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999875
 - jca in component ICaL (dimensionless): 0.999976
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001647
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.341431
 - xs1 in component IKs (dimensionless): 0.247492
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997344
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
06:31:45 (589986): called boinc_finish(0)

</stderr_txt>
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