𝕏

Task 55357127

Name HuVeMOp_20240626114313200281_ORdGradInc_k_24-Pueyo_APDR-conf_172_2
Workunit 26035180
Created 29 Jun 2024, 23:13:44 UTC
Sent 30 Jun 2024, 0:46:44 UTC
Report deadline 3 Jul 2024, 10:22:44 UTC
Received 2 Jul 2024, 15:29:09 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 218836
Run time 1 hours 42 min 21 sec
CPU time 58 min 43 sec
Validate state Valid
Credit 63.07
Device peak FLOPS 5.93 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.70 MB
Peak swap size 5.29 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626114313200281_ORdGradInc_k_24-Pueyo_APDR-conf_172.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626114313200281_ORdGradInc_k_24-Pueyo_APDR-conf_172_2_r1057697305_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626114313200281_ORdGradInc_k_24-Pueyo_APDR-conf_172_2_r1057697305_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 102.993077
     * GNaL_b in INaL: 0.006349
     * Gto_b in Ito: 0.091030
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.031960
     * GKs_b in IKs: 0.001823
     * GK1_b in IK1: 0.149044
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 69.871190
     * GKb_b in IKb: 0.004048
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.035366
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 10593775, states[0] = -16.308975, states[40]= 0.001275
Saving checkpoint... 
Iteration: 24234679, states[0] = -95.011388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 38471353, states[0] = -95.134574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 52345110, states[0] = -95.078920, states[40]= 0.000000
Saving checkpoint... 
Iteration: 63102930, states[0] = -21.247473, states[40]= 0.000894
Saving checkpoint... 
Iteration: 76836835, states[0] = -95.059483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 90624781, states[0] = -41.242465, states[40]= 0.000110
Saving checkpoint... 
Iteration: 104422903, states[0] = -95.087065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 118269637, states[0] = -94.992615, states[40]= 0.000000
Saving checkpoint... 
Iteration: 127344296, states[0] = -95.053242, states[40]= 0.000000
Saving checkpoint... 
Iteration: 140902672, states[0] = -95.077172, states[40]= 0.000000
Saving checkpoint... 
Iteration: 154208796, states[0] = -94.891580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 167286478, states[0] = -95.007649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 180681691, states[0] = -94.782959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 194350324, states[0] = -95.053792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 205418173, states[0] = -95.079984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 218999475, states[0] = -95.095686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 228407971, states[0] = -95.076841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 241928429, states[0] = -95.082463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 255332696, states[0] = -95.043269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 268925949, states[0] = -95.081751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 282218720, states[0] = -94.910173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 295606262, states[0] = -23.318976, states[40]= 0.000792
Saving checkpoint... 
Iteration: 309035064, states[0] = 17.038289, states[40]= 0.005349
Saving checkpoint... 
Iteration: 322518153, states[0] = 21.141963, states[40]= 0.011316
Saving checkpoint... 
Iteration: 335951750, states[0] = -95.087584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 349495796, states[0] = -95.094900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 363097914, states[0] = -15.644147, states[40]= 0.001365
Saving checkpoint... 
Iteration: 376780107, states[0] = -95.000010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 386290720, states[0] = -95.010627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 399924364, states[0] = -95.081201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 409908330, states[0] = -95.076663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 423167457, states[0] = -92.201924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 436649641, states[0] = -67.894699, states[40]= 0.000001
Saving checkpoint... 
Iteration: 450122315, states[0] = -38.316525, states[40]= 0.000168
Saving checkpoint... 
Iteration: 459641463, states[0] = -58.307389, states[40]= 0.000007
Saving checkpoint... 
Iteration: 472961281, states[0] = -95.089337, states[40]= 0.000000
Saving checkpoint... 
Iteration: 486528908, states[0] = 18.851326, states[40]= 0.005996
Saving checkpoint... 
Iteration: 496471612, states[0] = -95.091151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 510138103, states[0] = -54.625143, states[40]= 0.000013
Saving checkpoint... 
Iteration: 523430703, states[0] = -95.082729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 536964954, states[0] = -95.089965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 550772204, states[0] = -94.991197, states[40]= 0.000000
Saving checkpoint... 
Iteration: 564389071, states[0] = -95.070141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 577594471, states[0] = -12.541838, states[40]= 0.001823
Saving checkpoint... 
Iteration: 590883468, states[0] = -95.068028, states[40]= 0.000000
Saving checkpoint... 
Iteration: 604429373, states[0] = -95.082344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 617884948, states[0] = -95.068574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 631305331, states[0] = -95.023336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 644801916, states[0] = -95.020485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 658236555, states[0] = -94.941867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 671844579, states[0] = -95.049916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 685324248, states[0] = -95.037406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 698693727, states[0] = -94.855172, states[40]= 0.000000
Saving checkpoint... 
Iteration: 712065756, states[0] = 5.547687, states[40]= 0.004663
Saving checkpoint... 
Iteration: 725676099, states[0] = -94.577153, states[40]= 0.000000
Saving checkpoint... 
Iteration: 739084489, states[0] = -4.575136, states[40]= 0.003427
Saving checkpoint... 
Iteration: 752525431, states[0] = 19.732455, states[40]= 0.006692
Saving checkpoint... 
Iteration: 766833948, states[0] = -95.043625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 780799178, states[0] = -95.018043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 794307336, states[0] = -95.024851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 807702874, states[0] = -94.876897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 820936486, states[0] = -95.083920, states[40]= 0.000000
Saving checkpoint... 
Iteration: 834407672, states[0] = -95.076176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 848314375, states[0] = -95.030265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 861858425, states[0] = -95.056997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 875503628, states[0] = 32.390355, states[40]= 0.156690
Saving checkpoint... 
Iteration: 889528260, states[0] = 19.024455, states[40]= 0.006099
Saving checkpoint... 
Iteration: 903295527, states[0] = -95.014724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 916937094, states[0] = -95.083998, states[40]= 0.000000
Saving checkpoint... 
Iteration: 930780727, states[0] = -95.000287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 944629107, states[0] = -45.086367, states[40]= 0.000061
Saving checkpoint... 
Iteration: 958084037, states[0] = -4.264310, states[40]= 0.003488
Saving checkpoint... 
Iteration: 971468211, states[0] = -95.090249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 985508655, states[0] = 22.812953, states[40]= 0.072939
Saving checkpoint... 
Iteration: 999365480, states[0] = -95.060226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1010967442, states[0] = -95.090088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1024377712, states[0] = -95.065465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1038023477, states[0] = 20.172361, states[40]= 0.007315
Saving checkpoint... 
Iteration: 1051545968, states[0] = 13.315479, states[40]= 0.004912
Saving checkpoint... 
Iteration: 1064934595, states[0] = -95.083310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1078542163, states[0] = 14.666898, states[40]= 0.005004
Saving checkpoint... 
Iteration: 1091937243, states[0] = -95.083915, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1105451880, states[0] = -95.087087, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1118917796, states[0] = -95.078942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1132115728, states[0] = -32.072158, states[40]= 0.000380
Saving checkpoint... 
Iteration: 1142704831, states[0] = -94.880965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1155951153, states[0] = -95.086905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1169552487, states[0] = 10.912460, states[40]= 0.004829
Saving checkpoint... 
Iteration: 1182846036, states[0] = -95.050377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1196342552, states[0] = -95.048425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1210463193, states[0] = -95.089194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1223938519, states[0] = -95.084121, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1237583492, states[0] = -3.895440, states[40]= 0.003559
Saving checkpoint... 
Iteration: 1251269953, states[0] = -94.988117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1265248712, states[0] = -94.960295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1278768531, states[0] = -94.986420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1292556485, states[0] = 9.376254, states[40]= 0.004794
Saving checkpoint... 
Iteration: 1306300008, states[0] = -95.018408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1319944672, states[0] = -95.085430, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1333796746, states[0] = -95.015528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1347188694, states[0] = -94.838385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1360505562, states[0] = 25.978980, states[40]= 0.141188
Saving checkpoint... 
Iteration: 1374214662, states[0] = -94.901374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1387704791, states[0] = -94.880711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1400992439, states[0] = -95.093732, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1414273914, states[0] = -94.992556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1423699220, states[0] = -94.868223, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1432993988, states[0] = -95.093924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1446531545, states[0] = 18.109897, states[40]= 0.005659
Saving checkpoint... 
Iteration: 1459801973, states[0] = -95.019984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1472982492, states[0] = -95.092239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1486569775, states[0] = 3.723487, states[40]= 0.004552
Saving checkpoint... 
Iteration: 1496060109, states[0] = 7.931029, states[40]= 0.004756
Saving checkpoint... 
Iteration: 1509470971, states[0] = -95.151095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1522871377, states[0] = -5.160149, states[40]= 0.003719
Saving checkpoint... 
Iteration: 1536286423, states[0] = -95.368108, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1549752911, states[0] = -95.345503, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1563192746, states[0] = -95.252978, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1576586752, states[0] = -22.026652, states[40]= 0.000889
Saving checkpoint... 
Iteration: 1589903674, states[0] = -95.283402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1603243691, states[0] = 10.797293, states[40]= 0.005735
Saving checkpoint... 
Iteration: 1616857885, states[0] = -95.139146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1630226270, states[0] = 18.350353, states[40]= 0.007580
Saving checkpoint... 
Iteration: 1643821996, states[0] = -62.656667, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1657344419, states[0] = -93.523529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1671164187, states[0] = -95.186095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1684637142, states[0] = -86.143851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1698113369, states[0] = -51.975186, states[40]= 0.000022
Saving checkpoint... 
Iteration: 1711621575, states[0] = -62.163676, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1725150808, states[0] = -94.902554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1738716999, states[0] = -95.313271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1747967917, states[0] = -95.200264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1761544534, states[0] = -95.354109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1774983807, states[0] = -95.244167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1788347286, states[0] = 8.956115, states[40]= 0.005586
Saving checkpoint... 
Iteration: 1801688214, states[0] = -94.911613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1811589498, states[0] = -11.006836, states[40]= 0.002153
Saving checkpoint... 
Iteration: 1825375184, states[0] = -95.104502, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1839108699, states[0] = -26.942681, states[40]= 0.000624
Saving checkpoint... 
Iteration: 1852518296, states[0] = 20.981196, states[40]= 0.011045
Saving checkpoint... 
Iteration: 1866172334, states[0] = -94.266948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1879658606, states[0] = -81.842313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1889161046, states[0] = -85.504271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1902829992, states[0] = -95.044582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1916100346, states[0] = -18.013522, states[40]= 0.001116
Saving checkpoint... 
Iteration: 1929490629, states[0] = -95.095021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1943095467, states[0] = -13.489407, states[40]= 0.001668
Saving checkpoint... 
Iteration: 1956381674, states[0] = -95.067253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1969812033, states[0] = -95.028290, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1983483834, states[0] = -95.092448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1997129281, states[0] = -45.281402, states[40]= 0.000060
Saving checkpoint... 
Iteration: 2010484792, states[0] = -95.092351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2023699387, states[0] = -94.868270, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2037130092, states[0] = -46.108201, states[40]= 0.000053
Saving checkpoint... 
Iteration: 2050578771, states[0] = -0.951995, states[40]= 0.004053
Saving checkpoint... 
Iteration: 2060043276, states[0] = 14.275568, states[40]= 0.004973
Saving checkpoint... 
Iteration: 2073375009, states[0] = -95.063620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2085733122, states[0] = -94.935117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2099170397, states[0] = -93.608952, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.970102
 - CaMKt in component CaMK (millimolar): 0.007088
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.533752
 - nass in component intracellular_ions (millimolar): 6.533814
 - ki in component intracellular_ions (millimolar): 145.442718
 - kss in component intracellular_ions (millimolar): 145.442697
 - cansr in component intracellular_ions (millimolar): 1.315222
 - cajsr in component intracellular_ions (millimolar): 1.276817
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003594
 - hf in component INa (dimensionless): 0.881180
 - hs in component INa (dimensionless): 0.881175
 - j in component INa (dimensionless): 0.881143
 - hsp in component INa (dimensionless): 0.728053
 - jp in component INa (dimensionless): 0.881122
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.710693
 - hLp in component INaL (dimensionless): 0.450973
 - a in component Ito (dimensionless): 0.000621
 - iF in component Ito (dimensionless): 0.999871
 - iS in component Ito (dimensionless): 0.618384
 - ap in component Ito (dimensionless): 0.000316
 - iFp in component Ito (dimensionless): 0.999871
 - iSp in component Ito (dimensionless): 0.692889
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.934615
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999881
 - jca in component ICaL (dimensionless): 0.999977
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001612
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.329261
 - xs1 in component IKs (dimensionless): 0.245128
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997319
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
10:29:01 (14276): called boinc_finish(0)

</stderr_txt>
]]>


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