𝕏

Task 55356749

Name HuVeMOp_20240630011100300215_ORdGradInc_k_25-CLVPET-conf_113_1
Workunit 26285887
Created 29 Jun 2024, 23:13:16 UTC
Sent 30 Jun 2024, 0:42:49 UTC
Report deadline 3 Jul 2024, 3:35:37 UTC
Received 2 Jul 2024, 23:30:43 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 231343
Run time 59 min 7 sec
CPU time 47 min 45 sec
Validate state Valid
Credit 49.67
Device peak FLOPS 4.84 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.76 MB
Peak swap size 5.26 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630011100300215_ORdGradInc_k_25-CLVPET-conf_113.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630011100300215_ORdGradInc_k_25-CLVPET-conf_113_1_r953525516_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630011100300215_ORdGradInc_k_25-CLVPET-conf_113_1_r953525516_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 105.916579
     * GNaL_b in INaL: 0.006495
     * Gto_b in Ito: 0.095420
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031676
     * GKs_b in IKs: 0.001772
     * GK1_b in IK1: 0.178028
     * Gncx_b in INaCa_i: 0.000954
     * Pnak_b in INaK: 70.365165
     * GKb_b in IKb: 0.003771
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.021171
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 5451057, states[0] = -95.089356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 14954225, states[0] = -95.035229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 24258831, states[0] = -94.828516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 33704242, states[0] = -94.644698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 43072671, states[0] = 8.457088, states[40]= 0.004188
Saving checkpoint... 
Iteration: 52562249, states[0] = 13.224745, states[40]= 0.003393
Saving checkpoint... 
Iteration: 62009639, states[0] = 26.872271, states[40]= 0.057429
Saving checkpoint... 
Iteration: 71554511, states[0] = 16.393997, states[40]= 0.002740
Saving checkpoint... 
Iteration: 80905687, states[0] = -94.978705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 90506266, states[0] = 27.818028, states[40]= 0.178575
Saving checkpoint... 
Iteration: 100866484, states[0] = -94.954040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 110393407, states[0] = -94.971359, states[40]= 0.000000
Saving checkpoint... 
Iteration: 119734186, states[0] = -94.738479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 129205845, states[0] = -94.637795, states[40]= 0.000000
Saving checkpoint... 
Iteration: 138638448, states[0] = -46.396281, states[40]= 0.000174
Saving checkpoint... 
Iteration: 148099486, states[0] = -9.269919, states[40]= 0.002826
Saving checkpoint... 
Iteration: 157773346, states[0] = -94.835837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 167355885, states[0] = -94.944886, states[40]= 0.000000
Saving checkpoint... 
Iteration: 177085596, states[0] = 1.410796, states[40]= 0.004558
Saving checkpoint... 
Iteration: 186706002, states[0] = -94.637962, states[40]= 0.000000
Saving checkpoint... 
Iteration: 193310024, states[0] = -94.895972, states[40]= 0.000000
Saving checkpoint... 
Iteration: 202232633, states[0] = -94.732992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 211755915, states[0] = -94.797125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 221345482, states[0] = -94.935476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 230722946, states[0] = -94.701077, states[40]= 0.000000
Saving checkpoint... 
Iteration: 240030739, states[0] = 24.613879, states[40]= 0.001312
Saving checkpoint... 
Iteration: 249744834, states[0] = -94.768416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 259470764, states[0] = -95.000598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 269301886, states[0] = -94.884200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 278901265, states[0] = -94.974434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 288822065, states[0] = -94.910671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 298611848, states[0] = -20.971341, states[40]= 0.001317
Saving checkpoint... 
Iteration: 308204224, states[0] = -94.630143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 317780607, states[0] = -94.848960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 327472756, states[0] = -95.000804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 337007497, states[0] = 27.118345, states[40]= 0.118098
Saving checkpoint... 
Iteration: 346344100, states[0] = -94.933625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 355816213, states[0] = -94.903251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 365107704, states[0] = -17.037400, states[40]= 0.001518
Saving checkpoint... 
Iteration: 375154066, states[0] = -63.787206, states[40]= 0.000012
Saving checkpoint... 
Iteration: 384755909, states[0] = -94.796324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 394590952, states[0] = -2.224150, states[40]= 0.004241
Saving checkpoint... 
Iteration: 404275553, states[0] = -94.838994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 414189375, states[0] = -94.554157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 424108717, states[0] = -18.005026, states[40]= 0.001441
Saving checkpoint... 
Iteration: 433921607, states[0] = -94.983362, states[40]= 0.000000
Saving checkpoint... 
Iteration: 443484186, states[0] = -95.003014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 450776667, states[0] = -94.840947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 460394598, states[0] = -94.970032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 469538712, states[0] = 22.149749, states[40]= 0.001644
Saving checkpoint... 
Iteration: 478867960, states[0] = -94.952854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 488184479, states[0] = -94.481304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 497539261, states[0] = 21.966136, states[40]= 0.001674
Saving checkpoint... 
Iteration: 507125649, states[0] = -33.796381, states[40]= 0.000809
Saving checkpoint... 
Iteration: 516277709, states[0] = -94.842653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 526018730, states[0] = 27.015063, states[40]= 0.003442
Saving checkpoint... 
Iteration: 535677232, states[0] = -93.815951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 545460986, states[0] = -94.996690, states[40]= 0.000000
Saving checkpoint... 
Iteration: 555129080, states[0] = -37.045622, states[40]= 0.000578
Saving checkpoint... 
Iteration: 564605217, states[0] = -14.653163, states[40]= 0.001797
Saving checkpoint... 
Iteration: 574085318, states[0] = 1.588579, states[40]= 0.004564
Saving checkpoint... 
Iteration: 583687104, states[0] = -94.529389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 593682374, states[0] = -94.407096, states[40]= 0.000000
Saving checkpoint... 
Iteration: 603351535, states[0] = -94.939200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 612678299, states[0] = -94.024715, states[40]= 0.000000
Saving checkpoint... 
Iteration: 621995973, states[0] = -95.004712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 631400553, states[0] = -94.972513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 640687745, states[0] = -94.537032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 650087551, states[0] = 0.147037, states[40]= 0.004490
Saving checkpoint... 
Iteration: 659456681, states[0] = -94.994936, states[40]= 0.000000
Saving checkpoint... 
Iteration: 669435945, states[0] = -94.988011, states[40]= 0.000000
Saving checkpoint... 
Iteration: 679239482, states[0] = -94.751442, states[40]= 0.000000
Saving checkpoint... 
Iteration: 688930761, states[0] = -94.985966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 698822238, states[0] = -94.909071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 708259226, states[0] = -94.802780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 717912353, states[0] = -94.977990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 727368689, states[0] = -94.952297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 736809753, states[0] = -94.893179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 746185891, states[0] = -94.510128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 755467245, states[0] = -94.997499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 764865298, states[0] = -94.949623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 774405326, states[0] = -94.974340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 783535438, states[0] = 23.212944, states[40]= 0.001483
Saving checkpoint... 
Iteration: 792956202, states[0] = -94.994209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 802221229, states[0] = -94.692563, states[40]= 0.000000
Saving checkpoint... 
Iteration: 811764223, states[0] = -94.813671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 821133822, states[0] = -41.667768, states[40]= 0.000329
Saving checkpoint... 
Iteration: 830369702, states[0] = -94.952578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 839499229, states[0] = -95.004392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 849098922, states[0] = -8.749800, states[40]= 0.002943
Saving checkpoint... 
Iteration: 858197980, states[0] = -94.601085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 867411560, states[0] = -94.976963, states[40]= 0.000000
Saving checkpoint... 
Iteration: 876506167, states[0] = 27.914833, states[40]= 0.184474
Saving checkpoint... 
Iteration: 885669379, states[0] = -87.814033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 895270639, states[0] = -94.826984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 904785696, states[0] = -94.855501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 911766556, states[0] = -94.818317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 921375724, states[0] = -94.956384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 930878168, states[0] = -94.957976, states[40]= 0.000000
Saving checkpoint... 
Iteration: 940440464, states[0] = -94.988450, states[40]= 0.000000
Saving checkpoint... 
Iteration: 949956998, states[0] = -94.993759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 959108431, states[0] = -17.730163, states[40]= 0.001461
Saving checkpoint... 
Iteration: 968281520, states[0] = -94.847767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 977666013, states[0] = -82.079473, states[40]= 0.000001
Saving checkpoint... 
Iteration: 987165268, states[0] = -80.725203, states[40]= 0.000001
Saving checkpoint... 
Iteration: 996425804, states[0] = -94.982647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1005594430, states[0] = -4.899625, states[40]= 0.003786
Saving checkpoint... 
Iteration: 1015097908, states[0] = -7.844879, states[40]= 0.003149
Saving checkpoint... 
Iteration: 1024955430, states[0] = -94.992961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1034902583, states[0] = -94.971803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1044908554, states[0] = -94.974748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1054280832, states[0] = -94.846127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1063562771, states[0] = 13.059255, states[40]= 0.003439
Saving checkpoint... 
Iteration: 1073118954, states[0] = -27.569796, states[40]= 0.001216
Saving checkpoint... 
Iteration: 1082647243, states[0] = -55.840410, states[40]= 0.000042
Saving checkpoint... 
Iteration: 1092049640, states[0] = 18.277224, states[40]= 0.002359
Saving checkpoint... 
Iteration: 1101524226, states[0] = 26.196060, states[40]= 0.001436
Saving checkpoint... 
Iteration: 1110708920, states[0] = -94.645427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1120180705, states[0] = -94.302218, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1129582645, states[0] = 3.214889, states[40]= 0.004579
Saving checkpoint... 
Iteration: 1139084641, states[0] = 2.011131, states[40]= 0.004575
Saving checkpoint... 
Iteration: 1148264809, states[0] = -94.813475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1157503511, states[0] = 34.434434, states[40]= 0.425715
Saving checkpoint... 
Iteration: 1166842470, states[0] = -94.928483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1176066701, states[0] = 11.344330, states[40]= 0.003757
Saving checkpoint... 
Iteration: 1185158762, states[0] = -70.026206, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1191896230, states[0] = -94.967731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1201121410, states[0] = -29.842150, states[40]= 0.001096
Saving checkpoint... 
Iteration: 1210772167, states[0] = -94.828711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1220339031, states[0] = -94.924912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1229720765, states[0] = -94.689035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1239145201, states[0] = -53.588199, states[40]= 0.000060
Saving checkpoint... 
Iteration: 1248860015, states[0] = -94.943411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1258633473, states[0] = -41.318956, states[40]= 0.000344
Saving checkpoint... 
Iteration: 1268221943, states[0] = -94.692988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1274789048, states[0] = -94.859614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1283889703, states[0] = -94.963617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1293647041, states[0] = -55.614710, states[40]= 0.000044
Saving checkpoint... 
Iteration: 1303215853, states[0] = -94.670996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1312493398, states[0] = -95.001175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1319084995, states[0] = 1.792078, states[40]= 0.004570
Saving checkpoint... 
Iteration: 1328205969, states[0] = -94.632705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1334958873, states[0] = -94.992626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1344334968, states[0] = -94.920268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1353920171, states[0] = -94.978717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1363106850, states[0] = -16.215871, states[40]= 0.001600
Saving checkpoint... 
Iteration: 1372047247, states[0] = 19.160701, states[40]= 0.002183
Saving checkpoint... 
Iteration: 1381398697, states[0] = -94.968241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1390870323, states[0] = -94.950566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1399628544, states[0] = -36.530408, states[40]= 0.000612
Saving checkpoint... 
Iteration: 1408867749, states[0] = -94.948621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1418229542, states[0] = -94.717778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1427805790, states[0] = -94.884695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1437238237, states[0] = -94.744454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1446510034, states[0] = 26.902647, states[40]= 0.050264
Saving checkpoint... 
Iteration: 1455894249, states[0] = -94.965474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1465606149, states[0] = -15.543420, states[40]= 0.001678
Saving checkpoint... 
Iteration: 1475483789, states[0] = -94.998409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1485153884, states[0] = -63.553414, states[40]= 0.000012
Saving checkpoint... 
Iteration: 1494978070, states[0] = -94.996998, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1504625433, states[0] = -9.565642, states[40]= 0.004111
Saving checkpoint... 
Iteration: 1514589543, states[0] = -17.738308, states[40]= 0.002018
Saving checkpoint... 
Iteration: 1524347792, states[0] = -9.705847, states[40]= 0.002677
Saving checkpoint... 
Iteration: 1533839400, states[0] = -2.343064, states[40]= 0.004030
Saving checkpoint... 
Iteration: 1543337712, states[0] = -94.780680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1552825150, states[0] = 9.054825, states[40]= 0.003741
Saving checkpoint... 
Iteration: 1562310487, states[0] = -94.645970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1571472502, states[0] = -94.768692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1580906256, states[0] = -94.728078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1590295064, states[0] = -94.703715, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1599813153, states[0] = -94.529200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1609229268, states[0] = -94.694566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1618536519, states[0] = -94.635989, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1627626070, states[0] = -16.985558, states[40]= 0.001535
Saving checkpoint... 
Iteration: 1637005820, states[0] = -94.606600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1646355536, states[0] = -94.608738, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1655582954, states[0] = -94.600154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1664638319, states[0] = -94.593611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1673861936, states[0] = -94.599066, states[40]= 0.000000
Total time: 3360000.000000
State Variables:
 - v in component membrane (millivolt): -94.463754
 - CaMKt in component CaMK (millimolar): 0.001163
 - cass in component intracellular_ions (millimolar): 0.000088
 - nai in component intracellular_ions (millimolar): 6.369433
 - nass in component intracellular_ions (millimolar): 6.369521
 - ki in component intracellular_ions (millimolar): 145.518571
 - kss in component intracellular_ions (millimolar): 145.518559
 - cansr in component intracellular_ions (millimolar): 1.588946
 - cajsr in component intracellular_ions (millimolar): 1.589006
 - cai in component intracellular_ions (millimolar): 0.000091
 - m in component INa (dimensionless): 0.003782
 - hf in component INa (dimensionless): 0.872187
 - hs in component INa (dimensionless): 0.872187
 - j in component INa (dimensionless): 0.872188
 - hsp in component INa (dimensionless): 0.711301
 - jp in component INa (dimensionless): 0.872189
 - mL in component INaL (dimensionless): 0.000054
 - hL in component INaL (dimensionless): 0.717467
 - hLp in component INaL (dimensionless): 0.525886
 - a in component Ito (dimensionless): 0.000642
 - iF in component Ito (dimensionless): 0.999859
 - iS in component Ito (dimensionless): 0.997769
 - ap in component Ito (dimensionless): 0.000327
 - iFp in component Ito (dimensionless): 0.999859
 - iSp in component Ito (dimensionless): 0.999267
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998833
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003164
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.001735
 - xs1 in component IKs (dimensionless): 0.023306
 - xs2 in component IKs (dimensionless): 0.000092
 - xk1 in component IK1 (dimensionless): 0.997450
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
09:30:32 (4596): called boinc_finish(0)

</stderr_txt>
]]>


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