𝕏

Task 55356275

Name HuVeMOp_20240630011100300215_ORdGradInc_k_25-Pueyo_APDR-conf_609_1
Workunit 26285651
Created 29 Jun 2024, 23:12:39 UTC
Sent 30 Jun 2024, 0:48:41 UTC
Report deadline 3 Jul 2024, 10:24:41 UTC
Received 30 Jun 2024, 13:27:33 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 230980
Run time 8 hours 36 min 10 sec
CPU time 8 hours 36 min 10 sec
Validate state Valid
Credit 60.14
Device peak FLOPS 1.23 GFLOPS
Application version Human ventricular cell models optimization v0.02
aarch64-unknown-linux-gnu
Peak working set size 2.18 MB
Peak swap size 11.08 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>7.16.16</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630011100300215_ORdGradInc_k_25-Pueyo_APDR-conf_609.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630011100300215_ORdGradInc_k_25-Pueyo_APDR-conf_609_1_r622119428_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630011100300215_ORdGradInc_k_25-Pueyo_APDR-conf_609_1_r622119428_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 113.373448
     * GNaL_b in INaL: 0.004934
     * Gto_b in Ito: 0.096156
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032486
     * GKs_b in IKs: 0.001771
     * GK1_b in IK1: 0.180317
     * Gncx_b in INaCa_i: 0.000957
     * Pnak_b in INaK: 71.421979
     * GKb_b in IKb: 0.003713
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.043937
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12233902, states[0] = -95.152433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 24450624, states[0] = -95.232331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 37663405, states[0] = -94.848687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 49871812, states[0] = -95.185006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 62087233, states[0] = -10.633619, states[40]= 0.002197
Saving checkpoint... 
Iteration: 74376863, states[0] = -95.174807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 86571871, states[0] = 0.745999, states[40]= 0.004282
Saving checkpoint... 
Iteration: 98775252, states[0] = -95.114311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 110968020, states[0] = -95.187274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 123182167, states[0] = -94.978829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 135494747, states[0] = -95.188653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 147722469, states[0] = -95.049764, states[40]= 0.000000
Saving checkpoint... 
Iteration: 159917939, states[0] = -95.175802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 172142620, states[0] = -68.577013, states[40]= 0.000001
Saving checkpoint... 
Iteration: 184410571, states[0] = -95.173697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 196670637, states[0] = -94.926871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 208913709, states[0] = -95.174189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 221156044, states[0] = -91.217067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 233405723, states[0] = -95.172198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 245643835, states[0] = -70.338334, states[40]= 0.000001
Saving checkpoint... 
Iteration: 245749097, states[0] = -95.083166, states[40]= 0.000000
Saving checkpoint... 
Iteration: 257983334, states[0] = -95.185606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 270227157, states[0] = -95.055270, states[40]= 0.000000
Saving checkpoint... 
Iteration: 282471919, states[0] = -95.184137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 294719082, states[0] = -95.043318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 306968109, states[0] = -95.183598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 319202734, states[0] = -95.016152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 331392925, states[0] = -95.168737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 343637365, states[0] = -61.436915, states[40]= 0.000004
Saving checkpoint... 
Iteration: 355863920, states[0] = -95.159588, states[40]= 0.000000
Saving checkpoint... 
Iteration: 368080914, states[0] = -4.635896, states[40]= 0.003426
Saving checkpoint... 
Iteration: 380300137, states[0] = -95.127857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 392522189, states[0] = 19.564483, states[40]= 0.007964
Saving checkpoint... 
Iteration: 404765029, states[0] = -95.099593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 417011059, states[0] = 21.317473, states[40]= 0.042207
Saving checkpoint... 
Iteration: 429263536, states[0] = -95.098135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 441518624, states[0] = 20.217546, states[40]= 0.010883
Saving checkpoint... 
Iteration: 453773065, states[0] = -95.106949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 465978449, states[0] = -95.184829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 478181821, states[0] = -94.975238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 490436750, states[0] = -95.178493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 502674745, states[0] = -94.954906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 514922719, states[0] = -95.175741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 527145933, states[0] = -73.721629, states[40]= 0.000001
Saving checkpoint... 
Iteration: 539386509, states[0] = -95.166783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 551615277, states[0] = -36.953193, states[40]= 0.000189
Saving checkpoint... 
Iteration: 563814793, states[0] = -95.136863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 576031715, states[0] = 17.124962, states[40]= 0.005659
Saving checkpoint... 
Iteration: 588260473, states[0] = -95.095001, states[40]= 0.000000
Saving checkpoint... 
Iteration: 600477100, states[0] = -95.184572, states[40]= 0.000000
Saving checkpoint... 
Iteration: 612704654, states[0] = -95.019348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 624906741, states[0] = -95.172090, states[40]= 0.000000
Saving checkpoint... 
Iteration: 637103043, states[0] = -24.835994, states[40]= 0.000681
Saving checkpoint... 
Iteration: 649311927, states[0] = -95.135125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 661525954, states[0] = 18.711601, states[40]= 0.006604
Saving checkpoint... 
Iteration: 673755396, states[0] = -95.089707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 685999130, states[0] = -95.187018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 698191216, states[0] = -94.994360, states[40]= 0.000000
Saving checkpoint... 
Iteration: 710415480, states[0] = -95.174056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 722650418, states[0] = -82.021970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 734869972, states[0] = -95.161452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 747079346, states[0] = -3.534467, states[40]= 0.003635
Saving checkpoint... 
Iteration: 759276940, states[0] = -95.110097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 771507508, states[0] = 22.799696, states[40]= 0.097791
Saving checkpoint... 
Iteration: 783743731, states[0] = -95.076501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 795976076, states[0] = -95.184314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 808188676, states[0] = -94.989277, states[40]= 0.000000
Saving checkpoint... 
Iteration: 820382048, states[0] = -95.165273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 832601350, states[0] = -23.178659, states[40]= 0.000760
Saving checkpoint... 
Iteration: 844822213, states[0] = -95.140817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 857044591, states[0] = 12.751658, states[40]= 0.004928
Saving checkpoint... 
Iteration: 869245374, states[0] = -95.078392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 881440337, states[0] = -95.178880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 893671094, states[0] = -94.930751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 905897977, states[0] = -95.169705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 918145122, states[0] = -72.370991, states[40]= 0.000001
Saving checkpoint... 
Iteration: 930353222, states[0] = -95.155156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 942567962, states[0] = 3.019079, states[40]= 0.004494
Saving checkpoint... 
Iteration: 954817929, states[0] = -95.138392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 967060540, states[0] = 6.437221, states[40]= 0.004692
Saving checkpoint... 
Iteration: 979296859, states[0] = -95.125228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 991529545, states[0] = 17.758322, states[40]= 0.005929
Saving checkpoint... 
Iteration: 1003770840, states[0] = -95.104600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1016009267, states[0] = 21.810072, states[40]= 0.064661
Saving checkpoint... 
Iteration: 1028229717, states[0] = -95.058314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1040413784, states[0] = -95.173459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1052609724, states[0] = -31.407451, states[40]= 0.000381
Saving checkpoint... 
Iteration: 1064791064, states[0] = -95.121042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1076985687, states[0] = -95.185295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1089196786, states[0] = -95.004753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1101392863, states[0] = -95.168207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1113599984, states[0] = -21.842064, states[40]= 0.000830
Saving checkpoint... 
Iteration: 1125811339, states[0] = -95.134459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1138008915, states[0] = 21.952654, states[40]= 0.070355
Saving checkpoint... 
Iteration: 1150238121, states[0] = -95.069354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1162462375, states[0] = -95.182218, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1174685488, states[0] = -94.982582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1186895328, states[0] = -95.168818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1199092415, states[0] = -14.479248, states[40]= 0.001525
Saving checkpoint... 
Iteration: 1211310485, states[0] = -95.133889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1223528454, states[0] = 18.061184, states[40]= 0.006097
Saving checkpoint... 
Iteration: 1235743760, states[0] = -95.076237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1247935544, states[0] = -95.177772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1260145995, states[0] = -73.825495, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1272359637, states[0] = -95.157409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1284569087, states[0] = 2.456974, states[40]= 0.004447
Saving checkpoint... 
Iteration: 1296777775, states[0] = -95.110447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1308979162, states[0] = -95.184362, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1321167631, states[0] = -94.869641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1333429663, states[0] = -95.176600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1345780811, states[0] = -95.112926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1358439445, states[0] = -95.178407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1370971863, states[0] = -95.183390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1383264561, states[0] = -95.098495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1395542520, states[0] = 13.505622, states[40]= 0.004986
Saving checkpoint... 
Iteration: 1407823447, states[0] = -95.141105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1420105431, states[0] = -27.176970, states[40]= 0.000572
Saving checkpoint... 
Iteration: 1432382976, states[0] = -95.165149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1444659582, states[0] = -93.698769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1456934320, states[0] = -95.177407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1469215064, states[0] = -95.036230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1481497262, states[0] = -95.186301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1493773594, states[0] = -95.106726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1506019059, states[0] = 20.527075, states[40]= 0.012337
Saving checkpoint... 
Iteration: 1518243366, states[0] = -95.359065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1530482078, states[0] = -95.280282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1542707248, states[0] = -49.021350, states[40]= 0.000033
Saving checkpoint... 
Iteration: 1554932747, states[0] = 15.226464, states[40]= 0.006499
Saving checkpoint... 
Iteration: 1567158610, states[0] = -95.401056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1579381507, states[0] = -95.299127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1591610800, states[0] = -54.626864, states[40]= 0.000014
Saving checkpoint... 
Iteration: 1603834545, states[0] = 14.293294, states[40]= 0.006306
Saving checkpoint... 
Iteration: 1616045068, states[0] = -95.394759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1628252308, states[0] = -95.230236, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1640447892, states[0] = 7.690778, states[40]= 0.005502
Saving checkpoint... 
Iteration: 1652642145, states[0] = -95.392884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1664848804, states[0] = -95.210404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1677051260, states[0] = 5.822523, states[40]= 0.005354
Saving checkpoint... 
Iteration: 1689252557, states[0] = -95.403237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1701531294, states[0] = -95.381421, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1713732871, states[0] = -91.104957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1725935476, states[0] = 13.836254, states[40]= 0.006220
Saving checkpoint... 
Iteration: 1738137809, states[0] = -95.388710, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1750338456, states[0] = -94.555580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1762544774, states[0] = 9.319411, states[40]= 0.005640
Saving checkpoint... 
Iteration: 1774750084, states[0] = -95.401012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1786949335, states[0] = -95.214871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1799148630, states[0] = 7.276847, states[40]= 0.005470
Saving checkpoint... 
Iteration: 1811381592, states[0] = -95.206354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1823630233, states[0] = -55.926031, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1835874829, states[0] = -95.183748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1848107906, states[0] = -30.725133, states[40]= 0.000409
Saving checkpoint... 
Iteration: 1860335630, states[0] = -95.157262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1872552746, states[0] = 9.491517, states[40]= 0.004795
Saving checkpoint... 
Iteration: 1884788114, states[0] = -95.123314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1897014321, states[0] = 20.795105, states[40]= 0.020928
Saving checkpoint... 
Iteration: 1909233700, states[0] = -95.065562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1921481137, states[0] = -95.185828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1933719502, states[0] = -95.044017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1945971237, states[0] = -95.183688, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1958222515, states[0] = -95.047914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1970482609, states[0] = -95.184683, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1982737535, states[0] = -95.068283, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1994981830, states[0] = -95.184368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2007256533, states[0] = -95.090099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2019490716, states[0] = -95.185278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2031740278, states[0] = -95.071479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2043986802, states[0] = -95.184773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2056229071, states[0] = -95.056710, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2068469262, states[0] = -95.182545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2080710169, states[0] = -95.027781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2092948277, states[0] = -95.179385, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -95.062000
 - CaMKt in component CaMK (millimolar): 0.006952
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.533267
 - nass in component intracellular_ions (millimolar): 6.533327
 - ki in component intracellular_ions (millimolar): 145.444744
 - kss in component intracellular_ions (millimolar): 145.444724
 - cansr in component intracellular_ions (millimolar): 1.308432
 - cajsr in component intracellular_ions (millimolar): 1.270679
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003560
 - hf in component INa (dimensionless): 0.882752
 - hs in component INa (dimensionless): 0.882748
 - j in component INa (dimensionless): 0.882723
 - hsp in component INa (dimensionless): 0.731039
 - jp in component INa (dimensionless): 0.882707
 - mL in component INaL (dimensionless): 0.000048
 - hL in component INaL (dimensionless): 0.715298
 - hLp in component INaL (dimensionless): 0.460396
 - a in component Ito (dimensionless): 0.000617
 - iF in component Ito (dimensionless): 0.999873
 - iS in component Ito (dimensionless): 0.626579
 - ap in component Ito (dimensionless): 0.000314
 - iFp in component Ito (dimensionless): 0.999873
 - iSp in component Ito (dimensionless): 0.703002
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.939514
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999898
 - jca in component ICaL (dimensionless): 0.999979
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001577
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.319782
 - xs1 in component IKs (dimensionless): 0.235193
 - xs2 in component IKs (dimensionless): 0.000086
 - xk1 in component IK1 (dimensionless): 0.997295
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
13:26:36 (648048): called boinc_finish(0)

</stderr_txt>
]]>


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