𝕏

Task 55354662

Name HuVeMOp_20240626065019623306_ORdGradInc_k_24-Pueyo_APDR-conf_982_2
Workunit 26024927
Created 29 Jun 2024, 19:59:13 UTC
Sent 30 Jun 2024, 0:27:13 UTC
Report deadline 3 Jul 2024, 10:03:13 UTC
Received 30 Jun 2024, 20:13:30 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 190411
Run time 2 hours 49 min 29 sec
CPU time 2 hours 48 min 45 sec
Validate state Valid
Credit 57.77
Device peak FLOPS 2.89 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.64 MB
Peak swap size 6.20 MB
Peak disk usage 0.27 MB

Stderr output

<core_client_version>7.16.5</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626065019623306_ORdGradInc_k_24-Pueyo_APDR-conf_982.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626065019623306_ORdGradInc_k_24-Pueyo_APDR-conf_982_2_r591615390_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626065019623306_ORdGradInc_k_24-Pueyo_APDR-conf_982_2_r591615390_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 118.972417
     * GNaL_b in INaL: 0.006779
     * Gto_b in Ito: 0.075854
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033262
     * GKs_b in IKs: 0.001927
     * GK1_b in IK1: 0.143357
     * Gncx_b in INaCa_i: 0.000955
     * Pnak_b in INaK: 68.650372
     * GKb_b in IKb: 0.003968
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033192
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12593181, states[0] = -19.069217, states[40]= 0.001037
Saving checkpoint... 
Iteration: 25572491, states[0] = -0.668623, states[40]= 0.004296
Saving checkpoint... 
Iteration: 38426179, states[0] = -94.942757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 51266205, states[0] = -94.836639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 64011303, states[0] = 23.951244, states[40]= 0.040898
Saving checkpoint... 
Iteration: 76688514, states[0] = -94.686972, states[40]= 0.000000
Saving checkpoint... 
Iteration: 89677506, states[0] = -94.630387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 102425447, states[0] = -94.910757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 115267632, states[0] = -94.816596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 127997053, states[0] = -94.920754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 140922865, states[0] = -94.906353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 153718873, states[0] = -94.740881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 166468403, states[0] = -94.914832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 179164575, states[0] = -93.481473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 191766730, states[0] = -94.812068, states[40]= 0.000000
Saving checkpoint... 
Iteration: 204183621, states[0] = -94.659584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 217064269, states[0] = 4.908933, states[40]= 0.004867
Saving checkpoint... 
Iteration: 229786157, states[0] = -94.832440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 241979535, states[0] = -94.915777, states[40]= 0.000000
Saving checkpoint... 
Iteration: 254339862, states[0] = -94.872308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 266662827, states[0] = -92.812945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 278985178, states[0] = -94.916509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 290987560, states[0] = -94.916823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 303207421, states[0] = -94.717052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 315539944, states[0] = 15.279657, states[40]= 0.005597
Saving checkpoint... 
Iteration: 327804984, states[0] = -94.848751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 339884871, states[0] = -94.892781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 352106684, states[0] = -28.648145, states[40]= 0.000525
Saving checkpoint... 
Iteration: 364354497, states[0] = -94.879875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 376652222, states[0] = -80.978042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 388874513, states[0] = -94.888767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 401211022, states[0] = -94.724273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 413603515, states[0] = -25.563894, states[40]= 0.000674
Saving checkpoint... 
Iteration: 425770911, states[0] = -94.816325, states[40]= 0.000000
Saving checkpoint... 
Iteration: 438137536, states[0] = -61.302255, states[40]= 0.000004
Saving checkpoint... 
Iteration: 450370707, states[0] = -94.887167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 462585000, states[0] = -8.052732, states[40]= 0.002814
Saving checkpoint... 
Iteration: 474745718, states[0] = -94.784005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 486939879, states[0] = -94.908375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 499208009, states[0] = -94.718129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 511252244, states[0] = -94.793160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 523520689, states[0] = 21.636873, states[40]= 0.010086
Saving checkpoint... 
Iteration: 535830370, states[0] = -94.866477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 548116675, states[0] = -38.516915, states[40]= 0.000158
Saving checkpoint... 
Iteration: 559525117, states[0] = 20.412590, states[40]= 0.007758
Saving checkpoint... 
Iteration: 570952716, states[0] = -94.910953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 582606499, states[0] = -28.467550, states[40]= 0.000534
Saving checkpoint... 
Iteration: 594260992, states[0] = -94.804496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 605839287, states[0] = -94.871720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 617444611, states[0] = -94.909307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 629020752, states[0] = 21.620590, states[40]= 0.010035
Saving checkpoint... 
Iteration: 640613884, states[0] = -35.718614, states[40]= 0.000233
Saving checkpoint... 
Iteration: 652294377, states[0] = -94.839655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 663853704, states[0] = -94.879315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 675525825, states[0] = 20.201795, states[40]= 0.007534
Saving checkpoint... 
Iteration: 687214518, states[0] = -94.731001, states[40]= 0.000000
Saving checkpoint... 
Iteration: 698807826, states[0] = -94.850765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 710454969, states[0] = -94.911304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 722158592, states[0] = -89.745279, states[40]= 0.000000
Saving checkpoint... 
Iteration: 733555534, states[0] = 8.893697, states[40]= 0.005091
Saving checkpoint... 
Iteration: 745157507, states[0] = -88.548076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 756892557, states[0] = -94.895254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 768538537, states[0] = 15.819031, states[40]= 0.005686
Saving checkpoint... 
Iteration: 780105754, states[0] = -27.741780, states[40]= 0.000569
Saving checkpoint... 
Iteration: 791721757, states[0] = -94.744598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 804156618, states[0] = -87.445808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 815689565, states[0] = -94.677185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 827209340, states[0] = -94.720650, states[40]= 0.000000
Saving checkpoint... 
Iteration: 838682987, states[0] = -94.656300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 850281503, states[0] = -94.827370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 861950277, states[0] = -94.910316, states[40]= 0.000000
Saving checkpoint... 
Iteration: 873392807, states[0] = -94.895274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 884626919, states[0] = -49.363413, states[40]= 0.000031
Saving checkpoint... 
Iteration: 896164390, states[0] = -93.411704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 907721863, states[0] = -94.744727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 919122816, states[0] = -44.904375, states[40]= 0.000061
Saving checkpoint... 
Iteration: 930723177, states[0] = -94.747100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 942349875, states[0] = -94.877236, states[40]= 0.000000
Saving checkpoint... 
Iteration: 953919127, states[0] = -94.903132, states[40]= 0.000000
Saving checkpoint... 
Iteration: 965482400, states[0] = -94.915698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 977223944, states[0] = -94.748454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 989803544, states[0] = -94.847218, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1002286336, states[0] = -94.832043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1014321348, states[0] = -94.860372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1027174784, states[0] = -94.573395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1039952406, states[0] = -94.910632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1052515097, states[0] = 22.998969, states[40]= 0.019724
Saving checkpoint... 
Iteration: 1065223665, states[0] = -94.747903, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1077867296, states[0] = -94.885364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1090821474, states[0] = -94.860415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1103620765, states[0] = -42.730363, states[40]= 0.000085
Saving checkpoint... 
Iteration: 1116538573, states[0] = 15.805396, states[40]= 0.005683
Saving checkpoint... 
Iteration: 1129279890, states[0] = -94.825573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1141987428, states[0] = -94.916307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1154723899, states[0] = -94.748273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1167446168, states[0] = -94.909321, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1180175699, states[0] = -94.591412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1193125548, states[0] = -47.859373, states[40]= 0.000039
Saving checkpoint... 
Iteration: 1205816331, states[0] = -94.856787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1218593647, states[0] = -15.974406, states[40]= 0.001369
Saving checkpoint... 
Iteration: 1231555028, states[0] = 9.112939, states[40]= 0.005102
Saving checkpoint... 
Iteration: 1244353803, states[0] = -94.879039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1257403144, states[0] = -94.898400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1270497465, states[0] = -94.917549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1283460064, states[0] = -94.911919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1296560370, states[0] = 6.742213, states[40]= 0.004981
Saving checkpoint... 
Iteration: 1309350111, states[0] = -94.877151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1321863719, states[0] = -94.883654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1334637444, states[0] = -61.195004, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1347363248, states[0] = -94.883428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1360216393, states[0] = -94.734240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1373208387, states[0] = -94.718408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1385969922, states[0] = -94.913548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1398706709, states[0] = -94.714954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1411674564, states[0] = -94.568169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1424305819, states[0] = -94.848790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1437454302, states[0] = -94.910772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1450236986, states[0] = -94.770201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1462951953, states[0] = -94.910308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1475732191, states[0] = -94.762409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1488491988, states[0] = -94.916727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1501525054, states[0] = 20.032676, states[40]= 0.009237
Saving checkpoint... 
Iteration: 1514374911, states[0] = -95.172895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1527333437, states[0] = 16.021488, states[40]= 0.007073
Saving checkpoint... 
Iteration: 1540083261, states[0] = -95.061673, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1552710441, states[0] = -95.127303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1565670528, states[0] = -95.212959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1578473019, states[0] = -95.054341, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1591516136, states[0] = 22.737902, states[40]= 0.018428
Saving checkpoint... 
Iteration: 1604383606, states[0] = -95.232618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1617390577, states[0] = -29.901314, states[40]= 0.000461
Saving checkpoint... 
Iteration: 1630384006, states[0] = -95.088287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1643187475, states[0] = -26.500555, states[40]= 0.000630
Saving checkpoint... 
Iteration: 1656065698, states[0] = -3.620104, states[40]= 0.004216
Saving checkpoint... 
Iteration: 1668713224, states[0] = -56.756670, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1681704926, states[0] = -95.134348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1694974789, states[0] = -95.228155, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1708068424, states[0] = -95.049144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1720900138, states[0] = -40.783560, states[40]= 0.000117
Saving checkpoint... 
Iteration: 1733750109, states[0] = 6.874037, states[40]= 0.005737
Saving checkpoint... 
Iteration: 1746665968, states[0] = -3.861505, states[40]= 0.004163
Saving checkpoint... 
Iteration: 1759111733, states[0] = -95.147145, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1771629307, states[0] = -79.577055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1784241256, states[0] = -93.542303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1797152521, states[0] = -94.944939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1809870146, states[0] = -94.948809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1822860431, states[0] = -94.926705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1835355796, states[0] = -94.911116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1848159068, states[0] = -91.369176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1861009366, states[0] = 24.821075, states[40]= 0.062779
Saving checkpoint... 
Iteration: 1873671088, states[0] = -94.479565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1886382604, states[0] = -94.898069, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1899240846, states[0] = -94.780824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1912153503, states[0] = -83.270307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1925098098, states[0] = -20.403365, states[40]= 0.000951
Saving checkpoint... 
Iteration: 1938160683, states[0] = -91.631203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1951270534, states[0] = -94.816068, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1963904692, states[0] = -94.899163, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1976737400, states[0] = -94.771026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1989533122, states[0] = 17.804552, states[40]= 0.006171
Saving checkpoint... 
Iteration: 2002409212, states[0] = -94.899988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2015453539, states[0] = -94.910420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2028563057, states[0] = 5.490475, states[40]= 0.004906
Saving checkpoint... 
Iteration: 2041358132, states[0] = -94.880710, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2054255274, states[0] = -94.796356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2067508726, states[0] = 25.295682, states[40]= 0.072277
Saving checkpoint... 
Iteration: 2080575815, states[0] = -1.362619, states[40]= 0.004163
Saving checkpoint... 
Iteration: 2093876808, states[0] = -94.888698, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.793239
 - CaMKt in component CaMK (millimolar): 0.006772
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.634892
 - nass in component intracellular_ions (millimolar): 6.634952
 - ki in component intracellular_ions (millimolar): 145.344889
 - kss in component intracellular_ions (millimolar): 145.344869
 - cansr in component intracellular_ions (millimolar): 1.305834
 - cajsr in component intracellular_ions (millimolar): 1.268526
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003658
 - hf in component INa (dimensionless): 0.878103
 - hs in component INa (dimensionless): 0.878098
 - j in component INa (dimensionless): 0.878068
 - hsp in component INa (dimensionless): 0.722263
 - jp in component INa (dimensionless): 0.878047
 - mL in component INaL (dimensionless): 0.000051
 - hL in component INaL (dimensionless): 0.707642
 - hLp in component INaL (dimensionless): 0.450494
 - a in component Ito (dimensionless): 0.000628
 - iF in component Ito (dimensionless): 0.999867
 - iS in component Ito (dimensionless): 0.623872
 - ap in component Ito (dimensionless): 0.000320
 - iFp in component Ito (dimensionless): 0.999867
 - iSp in component Ito (dimensionless): 0.698736
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.936172
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999890
 - jca in component ICaL (dimensionless): 0.999980
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001589
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.341858
 - xs1 in component IKs (dimensionless): 0.236559
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997366
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
15:12:57 (18032): called boinc_finish(0)

</stderr_txt>
]]>


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