𝕏

Task 55353629

Name HuVeMOp_20240629202752950406_ORdGradInc_k_25-Pueyo_APDR-conf_794_1
Workunit 26284808
Created 29 Jun 2024, 18:35:57 UTC
Sent 30 Jun 2024, 0:17:03 UTC
Report deadline 3 Jul 2024, 9:53:03 UTC
Received 30 Jun 2024, 8:59:59 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 225163
Run time 2 hours 19 min 25 sec
CPU time 1 hours 41 min 44 sec
Validate state Valid
Credit 60.23
Device peak FLOPS 4.48 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.85 MB
Peak swap size 32.07 GB
Peak disk usage 0.27 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629202752950406_ORdGradInc_k_25-Pueyo_APDR-conf_794.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629202752950406_ORdGradInc_k_25-Pueyo_APDR-conf_794_1_r1370099719_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629202752950406_ORdGradInc_k_25-Pueyo_APDR-conf_794_1_r1370099719_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 92.398874
     * GNaL_b in INaL: 0.005091
     * Gto_b in Ito: 0.087765
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.030420
     * GKs_b in IKs: 0.001956
     * GK1_b in IK1: 0.176838
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 70.017564
     * GKb_b in IKb: 0.003742
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.027420
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 22783942, states[0] = -95.044639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 44863284, states[0] = -95.066221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 62816702, states[0] = -95.032007, states[40]= 0.000000
Saving checkpoint... 
Iteration: 87640987, states[0] = -57.585667, states[40]= 0.000008
Saving checkpoint... 
Iteration: 109739116, states[0] = -94.945898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 131906370, states[0] = -95.058393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 156441179, states[0] = -95.065615, states[40]= 0.000000
Saving checkpoint... 
Iteration: 181010157, states[0] = 22.606763, states[40]= 0.049084
Saving checkpoint... 
Iteration: 203793273, states[0] = -95.001187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 227014324, states[0] = 21.986665, states[40]= 0.019520
Saving checkpoint... 
Iteration: 253694406, states[0] = -94.864362, states[40]= 0.000000
Saving checkpoint... 
Iteration: 272442351, states[0] = -95.064913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 292306870, states[0] = -95.011236, states[40]= 0.000000
Saving checkpoint... 
Iteration: 317626691, states[0] = -42.106329, states[40]= 0.000100
Saving checkpoint... 
Iteration: 342615493, states[0] = -31.489193, states[40]= 0.000418
Saving checkpoint... 
Iteration: 363750565, states[0] = -94.957415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 388971820, states[0] = -95.069879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 411347276, states[0] = -95.034761, states[40]= 0.000000
Saving checkpoint... 
Iteration: 436306268, states[0] = -95.010686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 459697462, states[0] = -94.870460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 482199852, states[0] = -94.875252, states[40]= 0.000000
Saving checkpoint... 
Iteration: 507037119, states[0] = 16.654629, states[40]= 0.005142
Saving checkpoint... 
Iteration: 531396741, states[0] = -95.053536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 557004752, states[0] = 27.893332, states[40]= 0.160685
Saving checkpoint... 
Iteration: 581236515, states[0] = -94.938296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 606161087, states[0] = -86.473627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 627853184, states[0] = -95.037345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 652683548, states[0] = -94.834946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 678423286, states[0] = -95.060484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 703205987, states[0] = -94.887044, states[40]= 0.000000
Saving checkpoint... 
Iteration: 726034736, states[0] = 17.426664, states[40]= 0.005279
Saving checkpoint... 
Iteration: 750451185, states[0] = -95.066204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 777780334, states[0] = -94.989319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 802570331, states[0] = 3.673457, states[40]= 0.004556
Saving checkpoint... 
Iteration: 825413955, states[0] = -95.058091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 847415611, states[0] = -95.058495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 874322472, states[0] = -95.021035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 899421439, states[0] = -95.059886, states[40]= 0.000000
Saving checkpoint... 
Iteration: 923682624, states[0] = -94.830341, states[40]= 0.000000
Saving checkpoint... 
Iteration: 949118371, states[0] = -34.163880, states[40]= 0.000304
Saving checkpoint... 
Iteration: 973760917, states[0] = -94.969295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 997771236, states[0] = -94.980333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1022517259, states[0] = 21.612317, states[40]= 0.012097
Saving checkpoint... 
Iteration: 1047455436, states[0] = -95.066743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1070713377, states[0] = -94.900453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1095239586, states[0] = -94.942293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1116213850, states[0] = -94.901268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1140791041, states[0] = -94.998444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1165009450, states[0] = 22.799926, states[40]= 0.058368
Saving checkpoint... 
Iteration: 1190312111, states[0] = -95.014178, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1215607958, states[0] = -24.552458, states[40]= 0.000750
Saving checkpoint... 
Iteration: 1239845395, states[0] = -95.033246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1264248446, states[0] = -94.954061, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1288068561, states[0] = 4.501556, states[40]= 0.004611
Saving checkpoint... 
Iteration: 1312095261, states[0] = -12.949202, states[40]= 0.001761
Saving checkpoint... 
Iteration: 1337019777, states[0] = 21.218504, states[40]= 0.009106
Saving checkpoint... 
Iteration: 1362028353, states[0] = 19.306674, states[40]= 0.005920
Saving checkpoint... 
Iteration: 1387162860, states[0] = -89.213850, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1413248813, states[0] = -94.954421, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1437104862, states[0] = -21.713708, states[40]= 0.000880
Saving checkpoint... 
Iteration: 1460290685, states[0] = -94.997913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1482743781, states[0] = -94.947772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1503920124, states[0] = 21.305161, states[40]= 0.010753
Saving checkpoint... 
Iteration: 1525435242, states[0] = -95.237298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1549648331, states[0] = -94.688093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1571602380, states[0] = -95.209027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1598295900, states[0] = -95.200768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1616731047, states[0] = 16.986631, states[40]= 0.006570
Saving checkpoint... 
Iteration: 1642580486, states[0] = -14.671405, states[40]= 0.001699
Saving checkpoint... 
Iteration: 1665274492, states[0] = -95.304573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1689002632, states[0] = 38.899174, states[40]= 0.116287
Saving checkpoint... 
Iteration: 1717809965, states[0] = 23.404628, states[40]= 0.051843
Saving checkpoint... 
Iteration: 1737623046, states[0] = 19.913711, states[40]= 0.008367
Saving checkpoint... 
Iteration: 1759956417, states[0] = -95.093357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1787170019, states[0] = -4.632620, states[40]= 0.003889
Saving checkpoint... 
Iteration: 1809600497, states[0] = -20.727169, states[40]= 0.000954
Saving checkpoint... 
Iteration: 1832989154, states[0] = -95.093835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1854235495, states[0] = -94.948271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1876229337, states[0] = -94.933044, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1900847560, states[0] = -95.036830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1924600693, states[0] = -17.983013, states[40]= 0.001126
Saving checkpoint... 
Iteration: 1946611255, states[0] = -27.632647, states[40]= 0.000606
Saving checkpoint... 
Iteration: 1971505382, states[0] = 26.397178, states[40]= 0.146942
Saving checkpoint... 
Iteration: 1995781195, states[0] = -94.989341, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2020183980, states[0] = -94.835785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2048016498, states[0] = 21.716587, states[40]= 0.013480
Saving checkpoint... 
Iteration: 2071613286, states[0] = -29.449658, states[40]= 0.000516
Saving checkpoint... 
Iteration: 2094366214, states[0] = -95.041742, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.948157
 - CaMKt in component CaMK (millimolar): 0.007260
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.583072
 - nass in component intracellular_ions (millimolar): 6.583132
 - ki in component intracellular_ions (millimolar): 145.390569
 - kss in component intracellular_ions (millimolar): 145.390550
 - cansr in component intracellular_ions (millimolar): 1.325422
 - cajsr in component intracellular_ions (millimolar): 1.286815
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003602
 - hf in component INa (dimensionless): 0.880802
 - hs in component INa (dimensionless): 0.880797
 - j in component INa (dimensionless): 0.880769
 - hsp in component INa (dimensionless): 0.727342
 - jp in component INa (dimensionless): 0.880750
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.710419
 - hLp in component INaL (dimensionless): 0.451297
 - a in component Ito (dimensionless): 0.000622
 - iF in component Ito (dimensionless): 0.999871
 - iS in component Ito (dimensionless): 0.618196
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999871
 - iSp in component Ito (dimensionless): 0.692733
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.933684
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999880
 - jca in component ICaL (dimensionless): 0.999976
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001645
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.325060
 - xs1 in component IKs (dimensionless): 0.246223
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997325
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
03:59:49 (54952): called boinc_finish(0)

</stderr_txt>
]]>