𝕏

Task 55352244

Name HuVeMOp_20240629202752950406_ORdGradInc_k_25-Pueyo_APDR-conf_382_1
Workunit 26284116
Created 29 Jun 2024, 18:35:09 UTC
Sent 30 Jun 2024, 0:06:17 UTC
Report deadline 3 Jul 2024, 9:42:17 UTC
Received 30 Jun 2024, 5:41:25 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 228779
Run time 2 hours 18 min 58 sec
CPU time 2 hours 10 min 43 sec
Validate state Valid
Credit 62.06
Device peak FLOPS 4.70 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 2.14 MB
Peak swap size 4.13 GB
Peak disk usage 0.30 MB

Stderr output

<core_client_version>7.16.21</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629202752950406_ORdGradInc_k_25-Pueyo_APDR-conf_382.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629202752950406_ORdGradInc_k_25-Pueyo_APDR-conf_382_1_r112561029_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629202752950406_ORdGradInc_k_25-Pueyo_APDR-conf_382_1_r112561029_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 107.560311
     * GNaL_b in INaL: 0.006016
     * Gto_b in Ito: 0.081627
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030788
     * GKs_b in IKs: 0.001856
     * GK1_b in IK1: 0.162867
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 70.257745
     * GKb_b in IKb: 0.003674
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.019072
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 13176044, states[0] = -94.710088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 25870871, states[0] = -94.937341, states[40]= 0.000000
Saving checkpoint... 
Iteration: 38835269, states[0] = -94.902896, states[40]= 0.000000
Saving checkpoint... 
Iteration: 51909402, states[0] = -94.923419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 64616500, states[0] = -33.498722, states[40]= 0.000339
Saving checkpoint... 
Iteration: 77215025, states[0] = -94.745719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 90051296, states[0] = 11.613494, states[40]= 0.005042
Saving checkpoint... 
Iteration: 102491028, states[0] = -94.923995, states[40]= 0.000000
Saving checkpoint... 
Iteration: 114844443, states[0] = -94.880083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 128469586, states[0] = -94.918377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 141288603, states[0] = -94.838530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 154266241, states[0] = -94.814717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 167296274, states[0] = -94.844612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 180515125, states[0] = 22.663337, states[40]= 0.018148
Saving checkpoint... 
Iteration: 193087123, states[0] = -6.495798, states[40]= 0.003112
Saving checkpoint... 
Iteration: 206319447, states[0] = -94.861951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 218985454, states[0] = -94.918824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 231621265, states[0] = -37.117630, states[40]= 0.000211
Saving checkpoint... 
Iteration: 244601322, states[0] = -18.779915, states[40]= 0.001085
Saving checkpoint... 
Iteration: 257955049, states[0] = -94.913693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 270503055, states[0] = 37.593046, states[40]= 0.142431
Saving checkpoint... 
Iteration: 283344031, states[0] = -94.876661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 296403370, states[0] = -94.901051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 308227161, states[0] = -94.757810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 321215466, states[0] = -94.736684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 334306061, states[0] = -94.851870, states[40]= 0.000000
Saving checkpoint... 
Iteration: 346999372, states[0] = -94.920448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 359421873, states[0] = -94.906213, states[40]= 0.000000
Saving checkpoint... 
Iteration: 372961327, states[0] = -94.914726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 385752639, states[0] = -94.796554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 397164969, states[0] = -90.140658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 410343004, states[0] = -94.875999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 422805386, states[0] = -94.851277, states[40]= 0.000000
Saving checkpoint... 
Iteration: 435849862, states[0] = -94.879591, states[40]= 0.000000
Saving checkpoint... 
Iteration: 448820848, states[0] = -94.862531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 460709292, states[0] = -94.724616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 473017602, states[0] = 22.228883, states[40]= 0.012554
Saving checkpoint... 
Iteration: 486472714, states[0] = -94.916577, states[40]= 0.000000
Saving checkpoint... 
Iteration: 499586360, states[0] = -5.911848, states[40]= 0.003238
Saving checkpoint... 
Iteration: 511910582, states[0] = -94.903033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 524252969, states[0] = -94.796900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 536169638, states[0] = -93.370560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 548982898, states[0] = -94.918092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 562220413, states[0] = -94.745700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 574296026, states[0] = -94.843460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 587557127, states[0] = 9.410564, states[40]= 0.004971
Saving checkpoint... 
Iteration: 599777781, states[0] = -94.826147, states[40]= 0.000000
Saving checkpoint... 
Iteration: 613723948, states[0] = -94.752001, states[40]= 0.000000
Saving checkpoint... 
Iteration: 626291763, states[0] = -94.839664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 638936585, states[0] = -94.909573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 651586319, states[0] = -5.881469, states[40]= 0.003244
Saving checkpoint... 
Iteration: 664371215, states[0] = -94.889269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 677324422, states[0] = -94.864746, states[40]= 0.000000
Saving checkpoint... 
Iteration: 689451876, states[0] = -94.912747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 702651171, states[0] = -69.155533, states[40]= 0.000001
Saving checkpoint... 
Iteration: 715294391, states[0] = -94.841941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 728097040, states[0] = -14.866743, states[40]= 0.001503
Saving checkpoint... 
Iteration: 740894077, states[0] = -94.897758, states[40]= 0.000000
Saving checkpoint... 
Iteration: 753840492, states[0] = -94.874385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 766619329, states[0] = -35.296502, states[40]= 0.000270
Saving checkpoint... 
Iteration: 779284352, states[0] = -94.832625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 792205941, states[0] = -94.717675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 805590351, states[0] = -9.034254, states[40]= 0.002560
Saving checkpoint... 
Iteration: 818200064, states[0] = -94.705502, states[40]= 0.000000
Saving checkpoint... 
Iteration: 831169335, states[0] = -93.252494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 844405542, states[0] = -94.901329, states[40]= 0.000000
Saving checkpoint... 
Iteration: 856815806, states[0] = -94.858768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 869542231, states[0] = 15.131428, states[40]= 0.005231
Saving checkpoint... 
Iteration: 883211394, states[0] = -94.728464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 895394582, states[0] = -94.897823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 907941043, states[0] = -94.910376, states[40]= 0.000000
Saving checkpoint... 
Iteration: 920713061, states[0] = -94.731674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 934126607, states[0] = -42.241398, states[40]= 0.000101
Saving checkpoint... 
Iteration: 947228508, states[0] = -94.759664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 960123623, states[0] = -39.349815, states[40]= 0.000154
Saving checkpoint... 
Iteration: 972709752, states[0] = -94.725179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 985261808, states[0] = -94.807882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 997892438, states[0] = -94.897032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1011339096, states[0] = -94.873429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1024173760, states[0] = -94.281073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1037319855, states[0] = -94.861461, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1050220715, states[0] = -94.745919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1063152264, states[0] = -70.641855, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1075348161, states[0] = -94.878287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1087574261, states[0] = 1.607196, states[40]= 0.004496
Saving checkpoint... 
Iteration: 1099834111, states[0] = -94.870485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1112222765, states[0] = -94.749565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1124875543, states[0] = -94.890721, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1136731398, states[0] = -94.764368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1149645351, states[0] = -61.996558, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1162067438, states[0] = 4.961534, states[40]= 0.004779
Saving checkpoint... 
Iteration: 1175118986, states[0] = -34.976520, states[40]= 0.000282
Saving checkpoint... 
Iteration: 1187006086, states[0] = 26.952228, states[40]= 0.128109
Saving checkpoint... 
Iteration: 1200210084, states[0] = -94.725680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1212566397, states[0] = 5.438827, states[40]= 0.004807
Saving checkpoint... 
Iteration: 1225407673, states[0] = -94.901707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1238013902, states[0] = 22.881391, states[40]= 0.022681
Saving checkpoint... 
Iteration: 1249476017, states[0] = -94.916586, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1262805456, states[0] = -94.850766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1274954540, states[0] = -94.912868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1287833643, states[0] = -94.870080, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1299938135, states[0] = -94.909476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1312612229, states[0] = -28.744674, states[40]= 0.000567
Saving checkpoint... 
Iteration: 1325237026, states[0] = -94.773282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1338209317, states[0] = -94.724071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1351300013, states[0] = -94.846311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1363832698, states[0] = -94.869464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1376310097, states[0] = -94.854253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1389545269, states[0] = 14.013449, states[40]= 0.005144
Saving checkpoint... 
Iteration: 1401543590, states[0] = 14.634928, states[40]= 0.005189
Saving checkpoint... 
Iteration: 1414654936, states[0] = -74.538442, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1426795658, states[0] = -94.842567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1439574721, states[0] = 1.364048, states[40]= 0.004469
Saving checkpoint... 
Iteration: 1452306206, states[0] = -94.851225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1465639508, states[0] = -55.537053, states[40]= 0.000012
Saving checkpoint... 
Iteration: 1478731456, states[0] = -94.764232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1491651981, states[0] = -70.250683, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1504632778, states[0] = -70.497422, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1517131121, states[0] = 17.733535, states[40]= 0.007043
Saving checkpoint... 
Iteration: 1529751050, states[0] = 8.131933, states[40]= 0.005658
Saving checkpoint... 
Iteration: 1542702073, states[0] = -36.496013, states[40]= 0.000228
Saving checkpoint... 
Iteration: 1555557922, states[0] = 4.024710, states[40]= 0.005344
Saving checkpoint... 
Iteration: 1567513031, states[0] = 23.535856, states[40]= 0.028671
Saving checkpoint... 
Iteration: 1580074904, states[0] = -95.173226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1592434423, states[0] = 15.859739, states[40]= 0.006617
Saving checkpoint... 
Iteration: 1604990118, states[0] = -95.188606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1617942073, states[0] = 12.250232, states[40]= 0.006058
Saving checkpoint... 
Iteration: 1630468175, states[0] = -95.171526, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1642584014, states[0] = -18.359267, states[40]= 0.001227
Saving checkpoint... 
Iteration: 1654718341, states[0] = -95.109558, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1667736894, states[0] = 14.693794, states[40]= 0.006397
Saving checkpoint... 
Iteration: 1680625093, states[0] = 19.647149, states[40]= 0.008282
Saving checkpoint... 
Iteration: 1692684737, states[0] = -19.155686, states[40]= 0.001147
Saving checkpoint... 
Iteration: 1705188086, states[0] = -95.189353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1717546012, states[0] = 10.265065, states[40]= 0.005868
Saving checkpoint... 
Iteration: 1730768802, states[0] = -3.638928, states[40]= 0.004178
Saving checkpoint... 
Iteration: 1743228962, states[0] = -95.126295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1755454517, states[0] = -94.882398, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1768082869, states[0] = -95.039580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1781244628, states[0] = -93.099737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1794216779, states[0] = -95.107356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1807227842, states[0] = -94.803264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1820205416, states[0] = -94.751286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1832816759, states[0] = -94.884490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1845222206, states[0] = -94.766209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1857745229, states[0] = -94.797750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1870561932, states[0] = 7.234863, states[40]= 0.004903
Saving checkpoint... 
Iteration: 1882305554, states[0] = -94.856351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1895155112, states[0] = -75.289440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1907128822, states[0] = -44.630019, states[40]= 0.000070
Saving checkpoint... 
Iteration: 1919541191, states[0] = 15.478910, states[40]= 0.005269
Saving checkpoint... 
Iteration: 1932019440, states[0] = 21.865277, states[40]= 0.010228
Saving checkpoint... 
Iteration: 1944960454, states[0] = -94.914385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1957639545, states[0] = -55.625514, states[40]= 0.000012
Saving checkpoint... 
Iteration: 1970213116, states[0] = -94.731463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1982783715, states[0] = -94.831444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1995117947, states[0] = -34.023028, states[40]= 0.000318
Saving checkpoint... 
Iteration: 2007581434, states[0] = -2.533904, states[40]= 0.003907
Saving checkpoint... 
Iteration: 2019599411, states[0] = -17.031178, states[40]= 0.001243
Saving checkpoint... 
Iteration: 2032187776, states[0] = -94.674017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2045542959, states[0] = 14.865711, states[40]= 0.005208
Saving checkpoint... 
Iteration: 2058311474, states[0] = -94.854796, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2070802499, states[0] = -94.847829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2082624464, states[0] = -40.157816, states[40]= 0.000137
Saving checkpoint... 
Iteration: 2095918504, states[0] = -94.904114, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.795175
 - CaMKt in component CaMK (millimolar): 0.007218
 - cass in component intracellular_ions (millimolar): 0.000075
 - nai in component intracellular_ions (millimolar): 6.624420
 - nass in component intracellular_ions (millimolar): 6.624480
 - ki in component intracellular_ions (millimolar): 145.349107
 - kss in component intracellular_ions (millimolar): 145.349088
 - cansr in component intracellular_ions (millimolar): 1.329655
 - cajsr in component intracellular_ions (millimolar): 1.291253
 - cai in component intracellular_ions (millimolar): 0.000076
 - m in component INa (dimensionless): 0.003658
 - hf in component INa (dimensionless): 0.878137
 - hs in component INa (dimensionless): 0.878132
 - j in component INa (dimensionless): 0.878101
 - hsp in component INa (dimensionless): 0.722326
 - jp in component INa (dimensionless): 0.878080
 - mL in component INaL (dimensionless): 0.000051
 - hL in component INaL (dimensionless): 0.706200
 - hLp in component INaL (dimensionless): 0.446208
 - a in component Ito (dimensionless): 0.000628
 - iF in component Ito (dimensionless): 0.999867
 - iS in component Ito (dimensionless): 0.617053
 - ap in component Ito (dimensionless): 0.000320
 - iFp in component Ito (dimensionless): 0.999867
 - iSp in component Ito (dimensionless): 0.690876
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.932649
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999876
 - jca in component ICaL (dimensionless): 0.999976
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001680
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.341357
 - xs1 in component IKs (dimensionless): 0.246223
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997365
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
00:48:53 (91394): called boinc_finish(0)

</stderr_txt>
]]>


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