𝕏

Task 55352125

Name HuVeMOp_20240629202752950406_ORdGradInc_k_25-Schmidt_666-conf_680_0
Workunit 26284057
Created 29 Jun 2024, 18:35:03 UTC
Sent 30 Jun 2024, 0:06:17 UTC
Report deadline 3 Jul 2024, 0:06:21 UTC
Received 30 Jun 2024, 7:52:11 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 228779
Run time 1 hours 38 min 16 sec
CPU time 1 hours 32 min 50 sec
Validate state Valid
Credit 44.56
Device peak FLOPS 4.70 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.86 MB
Peak swap size 4.13 GB
Peak disk usage 0.23 MB

Stderr output

<core_client_version>7.16.21</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629202752950406_ORdGradInc_k_25-Schmidt_666-conf_680.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629202752950406_ORdGradInc_k_25-Schmidt_666-conf_680_0_r1400190580_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629202752950406_ORdGradInc_k_25-Schmidt_666-conf_680_0_r1400190580_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000150.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 92.160330
     * GNaL_b in INaL: 0.005669
     * Gto_b in Ito: 0.090578
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033277
     * GKs_b in IKs: 0.001857
     * GK1_b in IK1: 0.168682
     * Gncx_b in INaCa_i: 0.000971
     * Pnak_b in INaK: 70.122404
     * GKb_b in IKb: 0.003821
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029963
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 4500.000000
     * CL_0 in membrane: 666.700000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499741650.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 12996819, states[0] = -84.673127, states[40]= 0.000001
Saving checkpoint... 
Iteration: 25303636, states[0] = -84.615248, states[40]= 0.000001
Saving checkpoint... 
Iteration: 38334325, states[0] = -84.670222, states[40]= 0.000001
Saving checkpoint... 
Iteration: 50895548, states[0] = -84.361121, states[40]= 0.000000
Saving checkpoint... 
Iteration: 64012728, states[0] = 30.143487, states[40]= 0.074192
Saving checkpoint... 
Iteration: 76577345, states[0] = -84.433801, states[40]= 0.000001
Saving checkpoint... 
Iteration: 89308710, states[0] = -84.631818, states[40]= 0.000001
Saving checkpoint... 
Iteration: 102080996, states[0] = 2.892229, states[40]= 0.000108
Saving checkpoint... 
Iteration: 115575583, states[0] = -84.418424, states[40]= 0.000001
Saving checkpoint... 
Iteration: 127643056, states[0] = -84.630771, states[40]= 0.000001
Saving checkpoint... 
Iteration: 140064514, states[0] = 14.235464, states[40]= 0.000023
Saving checkpoint... 
Iteration: 152757820, states[0] = -3.208509, states[40]= 0.000161
Saving checkpoint... 
Iteration: 164860197, states[0] = -84.079787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 178119487, states[0] = -33.609888, states[40]= 0.000083
Saving checkpoint... 
Iteration: 190126800, states[0] = -41.063451, states[40]= 0.000046
Saving checkpoint... 
Iteration: 203154466, states[0] = -73.571470, states[40]= 0.000001
Saving checkpoint... 
Iteration: 215736755, states[0] = 13.229754, states[40]= 0.000027
Saving checkpoint... 
Iteration: 228310458, states[0] = -84.620067, states[40]= 0.000001
Saving checkpoint... 
Iteration: 241425465, states[0] = -0.275468, states[40]= 0.000138
Saving checkpoint... 
Iteration: 254129693, states[0] = -40.724195, states[40]= 0.000047
Saving checkpoint... 
Iteration: 266688326, states[0] = 29.646325, states[40]= 0.114259
Saving checkpoint... 
Iteration: 279588628, states[0] = -84.437576, states[40]= 0.000001
Saving checkpoint... 
Iteration: 292405277, states[0] = 14.334247, states[40]= 0.000022
Saving checkpoint... 
Iteration: 304505066, states[0] = -82.956989, states[40]= 0.000000
Saving checkpoint... 
Iteration: 317451176, states[0] = -23.863595, states[40]= 0.000102
Saving checkpoint... 
Iteration: 329484443, states[0] = -60.906176, states[40]= 0.000004
Saving checkpoint... 
Iteration: 341515422, states[0] = -83.796897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 354842357, states[0] = -83.232533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 367574493, states[0] = -84.342453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 380806865, states[0] = -45.354183, states[40]= 0.000029
Saving checkpoint... 
Iteration: 394724588, states[0] = 24.029447, states[40]= 0.000006
Saving checkpoint... 
Iteration: 408340533, states[0] = -84.655331, states[40]= 0.000001
Saving checkpoint... 
Iteration: 420908362, states[0] = -84.328990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 433861372, states[0] = -83.951202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 446460803, states[0] = -27.491835, states[40]= 0.000102
Saving checkpoint... 
Iteration: 461777485, states[0] = -7.335186, states[40]= 0.000167
Saving checkpoint... 
Iteration: 478626882, states[0] = -84.538211, states[40]= 0.000001
Saving checkpoint... 
Iteration: 493871067, states[0] = -84.020947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 493871068, states[0] = -84.020957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 506935518, states[0] = -84.441679, states[40]= 0.000001
Saving checkpoint... 
Iteration: 520046690, states[0] = 30.569505, states[40]= 0.001357
Saving checkpoint... 
Iteration: 532757991, states[0] = 10.113111, states[40]= 0.000044
Saving checkpoint... 
Iteration: 544909041, states[0] = -84.292890, states[40]= 0.000000
Saving checkpoint... 
Iteration: 557715867, states[0] = 30.423575, states[40]= 0.001085
Saving checkpoint... 
Iteration: 570068290, states[0] = 23.290395, states[40]= 0.000005
Saving checkpoint... 
Iteration: 583497112, states[0] = -60.853115, states[40]= 0.000004
Saving checkpoint... 
Iteration: 596013578, states[0] = -84.645847, states[40]= 0.000001
Saving checkpoint... 
Iteration: 608292037, states[0] = -84.509116, states[40]= 0.000001
Saving checkpoint... 
Iteration: 620721497, states[0] = 29.747616, states[40]= 0.000449
Saving checkpoint... 
Iteration: 633651519, states[0] = -84.581400, states[40]= 0.000001
Saving checkpoint... 
Iteration: 647181796, states[0] = -79.336809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 659960764, states[0] = -84.506063, states[40]= 0.000001
Saving checkpoint... 
Iteration: 672881984, states[0] = -84.035020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 685947238, states[0] = -84.449097, states[40]= 0.000001
Saving checkpoint... 
Iteration: 698485166, states[0] = -40.622254, states[40]= 0.000048
Saving checkpoint... 
Iteration: 712082406, states[0] = 19.883616, states[40]= 0.000008
Saving checkpoint... 
Iteration: 724413747, states[0] = 21.178249, states[40]= 0.000006
Saving checkpoint... 
Iteration: 737301999, states[0] = -84.517615, states[40]= 0.000001
Saving checkpoint... 
Iteration: 750410730, states[0] = 23.248696, states[40]= 0.000005
Saving checkpoint... 
Iteration: 763637466, states[0] = -84.519626, states[40]= 0.000001
Saving checkpoint... 
Iteration: 776827435, states[0] = -46.197135, states[40]= 0.000027
Saving checkpoint... 
Iteration: 789496454, states[0] = -48.121614, states[40]= 0.000021
Saving checkpoint... 
Iteration: 803111194, states[0] = 6.171298, states[40]= 0.000075
Saving checkpoint... 
Iteration: 815581827, states[0] = -84.237759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 828459272, states[0] = -4.121664, states[40]= 0.000164
Saving checkpoint... 
Iteration: 840747027, states[0] = 23.969741, states[40]= 0.000006
Saving checkpoint... 
Iteration: 853793154, states[0] = -3.455582, states[40]= 0.000161
Saving checkpoint... 
Iteration: 866482060, states[0] = -27.768133, states[40]= 0.000101
Saving checkpoint... 
Iteration: 879029763, states[0] = -84.642314, states[40]= 0.000001
Saving checkpoint... 
Iteration: 891968811, states[0] = -84.487809, states[40]= 0.000001
Saving checkpoint... 
Iteration: 905311807, states[0] = -84.518143, states[40]= 0.000001
Saving checkpoint... 
Iteration: 917771878, states[0] = 13.224259, states[40]= 0.000027
Saving checkpoint... 
Iteration: 931431077, states[0] = 17.646556, states[40]= 0.000012
Saving checkpoint... 
Iteration: 943360403, states[0] = -84.630614, states[40]= 0.000001
Saving checkpoint... 
Iteration: 956151176, states[0] = -25.447749, states[40]= 0.000102
Saving checkpoint... 
Iteration: 968887646, states[0] = -83.931265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 982062590, states[0] = 31.120807, states[40]= 0.017883
Saving checkpoint... 
Iteration: 995273996, states[0] = -84.335147, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1008229988, states[0] = -84.006789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1021043766, states[0] = -84.649968, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1033310762, states[0] = -84.489914, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1046781304, states[0] = 11.523836, states[40]= 0.000035
Saving checkpoint... 
Iteration: 1059003000, states[0] = -84.563185, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1072300062, states[0] = -84.440388, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1084852702, states[0] = -57.440546, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1097792770, states[0] = 6.060093, states[40]= 0.000076
Saving checkpoint... 
Iteration: 1110520176, states[0] = -56.884013, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1122406687, states[0] = 31.138319, states[40]= 0.004661
Saving checkpoint... 
Iteration: 1134218066, states[0] = -83.587766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1146812513, states[0] = -8.145639, states[40]= 0.000163
Saving checkpoint... 
Iteration: 1158410971, states[0] = 30.777678, states[40]= 0.001917
Saving checkpoint... 
Iteration: 1170135318, states[0] = 2.217630, states[40]= 0.000114
Saving checkpoint... 
Iteration: 1183191006, states[0] = -57.505844, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1195521762, states[0] = -53.786889, states[40]= 0.000011
Saving checkpoint... 
Iteration: 1209114643, states[0] = 16.053763, states[40]= 0.000016
Saving checkpoint... 
Iteration: 1221061882, states[0] = 31.778932, states[40]= 0.349391
Saving checkpoint... 
Iteration: 1234227886, states[0] = -83.807886, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1246749741, states[0] = 30.565793, states[40]= 0.001332
Saving checkpoint... 
Iteration: 1259888931, states[0] = -83.386559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1272544293, states[0] = -77.188289, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1284592982, states[0] = -84.136550, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1297163282, states[0] = -19.694735, states[40]= 0.000105
Saving checkpoint... 
Iteration: 1309525334, states[0] = -51.352683, states[40]= 0.000015
Saving checkpoint... 
Iteration: 1322736642, states[0] = 30.251976, states[40]= 0.554454
Saving checkpoint... 
Iteration: 1335157268, states[0] = -10.363805, states[40]= 0.000154
Saving checkpoint... 
Iteration: 1347831654, states[0] = -18.714003, states[40]= 0.000108
Saving checkpoint... 
Iteration: 1359860886, states[0] = -51.010666, states[40]= 0.000015
Saving checkpoint... 
Iteration: 1371678216, states[0] = -84.536341, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1385332185, states[0] = -84.494520, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1398679149, states[0] = -84.534448, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1411900278, states[0] = -83.683092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1425043005, states[0] = -84.603587, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1437786280, states[0] = 19.425050, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1450451976, states[0] = 20.231514, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1463600808, states[0] = -84.122947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1476692355, states[0] = -84.557605, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1489363866, states[0] = -84.567713, states[40]= 0.000001
Total time: 3000150.000000
State Variables:
 - v in component membrane (millivolt): -84.524809
 - CaMKt in component CaMK (millimolar): 0.039884
 - cass in component intracellular_ions (millimolar): 0.000103
 - nai in component intracellular_ions (millimolar): 6.884859
 - nass in component intracellular_ions (millimolar): 6.885015
 - ki in component intracellular_ions (millimolar): 144.766113
 - kss in component intracellular_ions (millimolar): 144.766085
 - cansr in component intracellular_ions (millimolar): 2.048101
 - cajsr in component intracellular_ions (millimolar): 1.789755
 - cai in component intracellular_ions (millimolar): 0.000104
 - m in component INa (dimensionless): 0.010284
 - hf in component INa (dimensionless): 0.571351
 - hs in component INa (dimensionless): 0.571200
 - j in component INa (dimensionless): 0.570379
 - hsp in component INa (dimensionless): 0.324454
 - jp in component INa (dimensionless): 0.569710
 - mL in component INaL (dimensionless): 0.000356
 - hL in component INaL (dimensionless): 0.347250
 - hLp in component INaL (dimensionless): 0.152175
 - a in component Ito (dimensionless): 0.001255
 - iF in component Ito (dimensionless): 0.999198
 - iS in component Ito (dimensionless): 0.369460
 - ap in component Ito (dimensionless): 0.000640
 - iFp in component Ito (dimensionless): 0.999198
 - iSp in component Ito (dimensionless): 0.404796
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.846632
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.996031
 - jca in component ICaL (dimensionless): 0.998217
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005828
 - xrf in component IKr (dimensionless): 0.000367
 - xrs in component IKr (dimensionless): 0.667788
 - xs1 in component IKs (dimensionless): 0.380483
 - xs2 in component IKs (dimensionless): 0.000282
 - xk1 in component IK1 (dimensionless): 0.996795
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
02:59:09 (92734): called boinc_finish(0)

</stderr_txt>
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