𝕏

Task 55352123

Name HuVeMOp_20240629202752950406_ORdGradInc_k_25-Schmidt_575-conf_580_0
Workunit 26284056
Created 29 Jun 2024, 18:35:03 UTC
Sent 30 Jun 2024, 0:06:17 UTC
Report deadline 3 Jul 2024, 0:06:27 UTC
Received 30 Jun 2024, 5:41:25 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 228779
Run time 1 hours 39 min 26 sec
CPU time 1 hours 33 min 5 sec
Validate state Valid
Credit 44.98
Device peak FLOPS 4.70 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.83 MB
Peak swap size 4.13 GB
Peak disk usage 0.20 MB

Stderr output

<core_client_version>7.16.21</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629202752950406_ORdGradInc_k_25-Schmidt_575-conf_580.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629202752950406_ORdGradInc_k_25-Schmidt_575-conf_580_0_r1229027556_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629202752950406_ORdGradInc_k_25-Schmidt_575-conf_580_0_r1229027556_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000350.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 116.832825
     * GNaL_b in INaL: 0.005586
     * Gto_b in Ito: 0.083761
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031330
     * GKs_b in IKs: 0.001933
     * GK1_b in IK1: 0.146477
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 71.484204
     * GKb_b in IKb: 0.003688
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.050080
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 5218.000000
     * CL_0 in membrane: 575.000000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499887500.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 13168232, states[0] = -84.583417, states[40]= 0.000001
Saving checkpoint... 
Iteration: 25724077, states[0] = -64.225260, states[40]= 0.000008
Saving checkpoint... 
Iteration: 38467591, states[0] = -84.543955, states[40]= 0.000001
Saving checkpoint... 
Iteration: 51112839, states[0] = -84.522662, states[40]= 0.000001
Saving checkpoint... 
Iteration: 64262691, states[0] = -79.934633, states[40]= 0.000001
Saving checkpoint... 
Iteration: 77870366, states[0] = -84.625466, states[40]= 0.000001
Saving checkpoint... 
Iteration: 90515327, states[0] = -84.604703, states[40]= 0.000001
Saving checkpoint... 
Iteration: 103457301, states[0] = -84.625031, states[40]= 0.000001
Saving checkpoint... 
Iteration: 116792176, states[0] = 7.907769, states[40]= 0.000179
Saving checkpoint... 
Iteration: 129242848, states[0] = -82.628641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 141882170, states[0] = -74.832788, states[40]= 0.000001
Saving checkpoint... 
Iteration: 154835785, states[0] = -83.620651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 167165716, states[0] = -55.272935, states[40]= 0.000024
Saving checkpoint... 
Iteration: 179274595, states[0] = -83.734033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 191827329, states[0] = 9.363661, states[40]= 0.000146
Saving checkpoint... 
Iteration: 202639834, states[0] = -84.602440, states[40]= 0.000001
Saving checkpoint... 
Iteration: 214887191, states[0] = -51.347187, states[40]= 0.000039
Saving checkpoint... 
Iteration: 227677452, states[0] = -84.698616, states[40]= 0.000001
Saving checkpoint... 
Iteration: 240258957, states[0] = -84.333985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 253467240, states[0] = -84.182342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 265602829, states[0] = -84.603090, states[40]= 0.000001
Saving checkpoint... 
Iteration: 278398960, states[0] = -22.341628, states[40]= 0.000283
Saving checkpoint... 
Iteration: 290900441, states[0] = -84.591460, states[40]= 0.000001
Saving checkpoint... 
Iteration: 303622013, states[0] = 30.504800, states[40]= 0.000887
Saving checkpoint... 
Iteration: 315400748, states[0] = 31.665478, states[40]= 0.019869
Saving checkpoint... 
Iteration: 327346056, states[0] = -84.066083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 339820503, states[0] = -84.747570, states[40]= 0.000001
Saving checkpoint... 
Iteration: 352605541, states[0] = -57.896772, states[40]= 0.000017
Saving checkpoint... 
Iteration: 366050570, states[0] = 10.437517, states[40]= 0.000125
Saving checkpoint... 
Iteration: 378586441, states[0] = -84.582082, states[40]= 0.000001
Saving checkpoint... 
Iteration: 391934588, states[0] = 4.660336, states[40]= 0.000263
Saving checkpoint... 
Iteration: 405126873, states[0] = 23.286247, states[40]= 0.000013
Saving checkpoint... 
Iteration: 418268401, states[0] = -84.612687, states[40]= 0.000001
Saving checkpoint... 
Iteration: 431408289, states[0] = -83.289839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 443968627, states[0] = 6.968283, states[40]= 0.000201
Saving checkpoint... 
Iteration: 456980887, states[0] = -73.318539, states[40]= 0.000002
Saving checkpoint... 
Iteration: 469459908, states[0] = -84.675442, states[40]= 0.000001
Saving checkpoint... 
Iteration: 482113128, states[0] = -84.686026, states[40]= 0.000001
Saving checkpoint... 
Iteration: 495052666, states[0] = -84.692355, states[40]= 0.000001
Saving checkpoint... 
Iteration: 507408472, states[0] = -84.669426, states[40]= 0.000001
Saving checkpoint... 
Iteration: 520263321, states[0] = -84.130736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 532811353, states[0] = 3.428306, states[40]= 0.000299
Saving checkpoint... 
Iteration: 545749063, states[0] = 3.278568, states[40]= 0.000304
Saving checkpoint... 
Iteration: 558328316, states[0] = 33.749626, states[40]= 0.659888
Saving checkpoint... 
Iteration: 571639162, states[0] = -10.580425, states[40]= 0.000438
Saving checkpoint... 
Iteration: 584376510, states[0] = -84.137360, states[40]= 0.000000
Saving checkpoint... 
Iteration: 597289834, states[0] = -81.404345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 610576011, states[0] = -84.447820, states[40]= 0.000001
Saving checkpoint... 
Iteration: 623130044, states[0] = -43.417386, states[40]= 0.000097
Saving checkpoint... 
Iteration: 635529986, states[0] = -82.501374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 648000131, states[0] = -84.680039, states[40]= 0.000001
Saving checkpoint... 
Iteration: 660377900, states[0] = -84.725811, states[40]= 0.000001
Saving checkpoint... 
Iteration: 672796468, states[0] = 19.714203, states[40]= 0.000024
Saving checkpoint... 
Iteration: 685658820, states[0] = -84.665992, states[40]= 0.000001
Saving checkpoint... 
Iteration: 698280283, states[0] = -84.543044, states[40]= 0.000001
Saving checkpoint... 
Iteration: 711101500, states[0] = -39.483312, states[40]= 0.000144
Saving checkpoint... 
Iteration: 724376398, states[0] = -83.832425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 737306948, states[0] = -83.021390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 750220507, states[0] = -60.707568, states[40]= 0.000011
Saving checkpoint... 
Iteration: 763115583, states[0] = -12.244841, states[40]= 0.000407
Saving checkpoint... 
Iteration: 774966619, states[0] = -82.190887, states[40]= 0.000000
Saving checkpoint... 
Iteration: 787811177, states[0] = 11.573873, states[40]= 0.000105
Saving checkpoint... 
Iteration: 800756056, states[0] = 7.019664, states[40]= 0.000199
Saving checkpoint... 
Iteration: 814324391, states[0] = -50.987272, states[40]= 0.000041
Saving checkpoint... 
Iteration: 826400507, states[0] = -52.225303, states[40]= 0.000035
Saving checkpoint... 
Iteration: 838899818, states[0] = -84.674003, states[40]= 0.000001
Saving checkpoint... 
Iteration: 851546932, states[0] = -84.663798, states[40]= 0.000001
Saving checkpoint... 
Iteration: 864565980, states[0] = 15.965481, states[40]= 0.000050
Saving checkpoint... 
Iteration: 877726097, states[0] = -84.715183, states[40]= 0.000001
Saving checkpoint... 
Iteration: 890194528, states[0] = -16.999734, states[40]= 0.000323
Saving checkpoint... 
Iteration: 902724576, states[0] = -84.671522, states[40]= 0.000001
Saving checkpoint... 
Iteration: 915616049, states[0] = -84.455934, states[40]= 0.000001
Saving checkpoint... 
Iteration: 927585287, states[0] = -35.329011, states[40]= 0.000201
Saving checkpoint... 
Iteration: 941170033, states[0] = -84.192180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 953213112, states[0] = -80.356722, states[40]= 0.000000
Saving checkpoint... 
Iteration: 965241607, states[0] = -28.311904, states[40]= 0.000273
Saving checkpoint... 
Iteration: 977836438, states[0] = 18.421181, states[40]= 0.000031
Saving checkpoint... 
Iteration: 989908631, states[0] = 19.892441, states[40]= 0.000023
Saving checkpoint... 
Iteration: 1002639137, states[0] = -53.473736, states[40]= 0.000030
Saving checkpoint... 
Iteration: 1015618291, states[0] = -83.987649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1028580514, states[0] = -84.284596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1040915403, states[0] = -83.893366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1053644399, states[0] = -84.600309, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1066554290, states[0] = -84.456566, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1079178667, states[0] = -84.267526, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1091632209, states[0] = -84.725976, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1104386425, states[0] = -22.267455, states[40]= 0.000283
Saving checkpoint... 
Iteration: 1117232882, states[0] = 30.513500, states[40]= 0.133917
Saving checkpoint... 
Iteration: 1129850498, states[0] = -84.668673, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1142328357, states[0] = -12.556806, states[40]= 0.000401
Saving checkpoint... 
Iteration: 1154881548, states[0] = -84.722623, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1167479383, states[0] = -84.525977, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1180678853, states[0] = -84.365874, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1193361106, states[0] = -84.559045, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1206338367, states[0] = -84.705978, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1219176137, states[0] = -84.115613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1231572507, states[0] = -84.408060, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1243780838, states[0] = 14.657283, states[40]= 0.000063
Saving checkpoint... 
Iteration: 1255278603, states[0] = 15.902132, states[40]= 0.000051
Saving checkpoint... 
Iteration: 1268823418, states[0] = -6.940393, states[40]= 0.000480
Saving checkpoint... 
Iteration: 1281299318, states[0] = -84.328866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1293911241, states[0] = -83.626753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1307689438, states[0] = -68.395882, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1319960804, states[0] = 18.760164, states[40]= 0.000029
Saving checkpoint... 
Iteration: 1333256887, states[0] = -45.425722, states[40]= 0.000078
Saving checkpoint... 
Iteration: 1345383839, states[0] = -84.042894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1357709999, states[0] = -63.007499, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1370983495, states[0] = -84.189982, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1383661749, states[0] = -84.415734, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1396882173, states[0] = -84.384038, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1408982919, states[0] = -84.537749, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1421481060, states[0] = -2.224458, states[40]= 0.000448
Saving checkpoint... 
Iteration: 1434236087, states[0] = -84.212744, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1446634818, states[0] = -84.479660, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1459962298, states[0] = 24.297589, states[40]= 0.000013
Saving checkpoint... 
Iteration: 1472543920, states[0] = -84.636822, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1485037584, states[0] = -23.619063, states[40]= 0.000281
Saving checkpoint... 
Iteration: 1498161142, states[0] = -84.725249, states[40]= 0.000001
Total time: 3000350.000000
State Variables:
 - v in component membrane (millivolt): -84.604268
 - CaMKt in component CaMK (millimolar): 0.054274
 - cass in component intracellular_ions (millimolar): 0.000111
 - nai in component intracellular_ions (millimolar): 6.838301
 - nass in component intracellular_ions (millimolar): 6.838476
 - ki in component intracellular_ions (millimolar): 144.766305
 - kss in component intracellular_ions (millimolar): 144.766275
 - cansr in component intracellular_ions (millimolar): 2.218900
 - cajsr in component intracellular_ions (millimolar): 1.852835
 - cai in component intracellular_ions (millimolar): 0.000111
 - m in component INa (dimensionless): 0.010203
 - hf in component INa (dimensionless): 0.574545
 - hs in component INa (dimensionless): 0.574286
 - j in component INa (dimensionless): 0.572822
 - hsp in component INa (dimensionless): 0.326999
 - jp in component INa (dimensionless): 0.571178
 - mL in component INaL (dimensionless): 0.000351
 - hL in component INaL (dimensionless): 0.318413
 - hLp in component INaL (dimensionless): 0.134685
 - a in component Ito (dimensionless): 0.001248
 - iF in component Ito (dimensionless): 0.999208
 - iS in component Ito (dimensionless): 0.303554
 - ap in component Ito (dimensionless): 0.000636
 - iFp in component Ito (dimensionless): 0.999208
 - iSp in component Ito (dimensionless): 0.333451
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.811678
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.990183
 - jca in component ICaL (dimensionless): 0.994228
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.007722
 - xrf in component IKr (dimensionless): 0.002111
 - xrs in component IKr (dimensionless): 0.730539
 - xs1 in component IKs (dimensionless): 0.427823
 - xs2 in component IKs (dimensionless): 0.000289
 - xk1 in component IK1 (dimensionless): 0.996777
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
01:15:31 (91957): called boinc_finish(0)

</stderr_txt>
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