𝕏

Task 55351297

Name HuVeMOp_20240629202752950406_ORdGradInc_k_25-Pueyo_APDR-conf_761_1
Workunit 26283648
Created 29 Jun 2024, 18:34:37 UTC
Sent 29 Jun 2024, 23:52:14 UTC
Report deadline 3 Jul 2024, 9:28:14 UTC
Received 3 Jul 2024, 1:31:41 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 215802
Run time 2 hours 53 min 40 sec
CPU time 2 hours 50 min 10 sec
Validate state Valid
Credit 62.01
Device peak FLOPS 3.11 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.20 MB
Peak swap size 6.24 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.20.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629202752950406_ORdGradInc_k_25-Pueyo_APDR-conf_761.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629202752950406_ORdGradInc_k_25-Pueyo_APDR-conf_761_1_r1622457653_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629202752950406_ORdGradInc_k_25-Pueyo_APDR-conf_761_1_r1622457653_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 104.618752
     * GNaL_b in INaL: 0.005940
     * Gto_b in Ito: 0.093334
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.029876
     * GKs_b in IKs: 0.001778
     * GK1_b in IK1: 0.163833
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 74.035223
     * GKb_b in IKb: 0.003799
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.049967
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 13211452, states[0] = -94.937336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 26507875, states[0] = 22.829915, states[40]= 0.088236
Saving checkpoint... 
Iteration: 39921135, states[0] = -95.030957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 53208834, states[0] = -94.846341, states[40]= 0.000000
Saving checkpoint... 
Iteration: 66552439, states[0] = 11.335835, states[40]= 0.004780
Saving checkpoint... 
Iteration: 80020317, states[0] = 20.923114, states[40]= 0.008962
Saving checkpoint... 
Iteration: 93375970, states[0] = -94.984485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 106709405, states[0] = -94.825268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 120087957, states[0] = -5.244136, states[40]= 0.003247
Saving checkpoint... 
Iteration: 133526409, states[0] = 19.806287, states[40]= 0.006383
Saving checkpoint... 
Iteration: 146845897, states[0] = -94.965379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 160175516, states[0] = -94.083507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 173325363, states[0] = -94.953310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 186572292, states[0] = 3.637450, states[40]= 0.004483
Saving checkpoint... 
Iteration: 199840753, states[0] = -94.961506, states[40]= 0.000000
Saving checkpoint... 
Iteration: 213194263, states[0] = -94.788829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 226374149, states[0] = -94.976066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 239598117, states[0] = -13.151592, states[40]= 0.001696
Saving checkpoint... 
Iteration: 252948474, states[0] = -94.995922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 266285645, states[0] = -94.923148, states[40]= 0.000000
Saving checkpoint... 
Iteration: 279493300, states[0] = -95.002630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 292811086, states[0] = -94.943295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 306197890, states[0] = -94.797053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 319306498, states[0] = -94.940001, states[40]= 0.000000
Saving checkpoint... 
Iteration: 332670552, states[0] = -91.829969, states[40]= 0.000000
Saving checkpoint... 
Iteration: 345831226, states[0] = -94.955925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 358999309, states[0] = -95.003256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 371938972, states[0] = -94.993939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 385313866, states[0] = -94.945121, states[40]= 0.000000
Saving checkpoint... 
Iteration: 398749762, states[0] = -94.883876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 412038139, states[0] = 16.539034, states[40]= 0.005097
Saving checkpoint... 
Iteration: 425496964, states[0] = -95.002939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 438847899, states[0] = -94.964600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 452055967, states[0] = 10.338524, states[40]= 0.004749
Saving checkpoint... 
Iteration: 465175223, states[0] = -94.000147, states[40]= 0.000000
Saving checkpoint... 
Iteration: 478425698, states[0] = -94.991002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 491502307, states[0] = 41.431889, states[40]= 0.107040
Saving checkpoint... 
Iteration: 504645668, states[0] = -57.950924, states[40]= 0.000007
Saving checkpoint... 
Iteration: 517797576, states[0] = -94.933057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 530907931, states[0] = -94.986528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 544056417, states[0] = 10.170731, states[40]= 0.004746
Saving checkpoint... 
Iteration: 557136305, states[0] = -48.164262, states[40]= 0.000039
Saving checkpoint... 
Iteration: 570216226, states[0] = -94.832102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 583322508, states[0] = -94.950585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 596397429, states[0] = -94.983487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 609587708, states[0] = -4.934268, states[40]= 0.003306
Saving checkpoint... 
Iteration: 622678637, states[0] = -94.496613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 635879384, states[0] = -94.977560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 648998659, states[0] = -95.002985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 662286330, states[0] = -94.923454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 675584371, states[0] = -2.755352, states[40]= 0.003711
Saving checkpoint... 
Iteration: 688795579, states[0] = -94.931333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 701888642, states[0] = -94.980669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 715195868, states[0] = -94.792218, states[40]= 0.000000
Saving checkpoint... 
Iteration: 728437444, states[0] = -94.993387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 741725171, states[0] = -94.847353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 754996761, states[0] = -95.002695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 768210313, states[0] = -94.821198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 781279350, states[0] = -94.916897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 794522209, states[0] = 20.704224, states[40]= 0.007808
Saving checkpoint... 
Iteration: 807802188, states[0] = -94.936456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 820958957, states[0] = -94.997326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 834086638, states[0] = -4.210936, states[40]= 0.003447
Saving checkpoint... 
Iteration: 847296390, states[0] = -94.931885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 860519612, states[0] = 21.136926, states[40]= 0.009608
Saving checkpoint... 
Iteration: 873760053, states[0] = -94.896297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 886966581, states[0] = -94.998516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 900204497, states[0] = -94.810051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 913486838, states[0] = -95.001372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 926713838, states[0] = -94.827568, states[40]= 0.000000
Saving checkpoint... 
Iteration: 939960246, states[0] = -94.997462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 953251669, states[0] = -94.885966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 966562041, states[0] = 8.009928, states[40]= 0.004696
Saving checkpoint... 
Iteration: 979703215, states[0] = -94.807489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 992989908, states[0] = -95.001708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1006346204, states[0] = -94.963395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1019585546, states[0] = -3.497014, states[40]= 0.003580
Saving checkpoint... 
Iteration: 1032957073, states[0] = -94.996866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1046254430, states[0] = -94.889386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1059579440, states[0] = 0.094157, states[40]= 0.004135
Saving checkpoint... 
Iteration: 1072761414, states[0] = -94.897750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1085748335, states[0] = -94.881539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1098870725, states[0] = -94.974036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1112103069, states[0] = -17.522103, states[40]= 0.001153
Saving checkpoint... 
Iteration: 1125524546, states[0] = 20.243380, states[40]= 0.006878
Saving checkpoint... 
Iteration: 1138885227, states[0] = -94.979246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1151990942, states[0] = -95.001730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1165120931, states[0] = -33.492311, states[40]= 0.000330
Saving checkpoint... 
Iteration: 1178400263, states[0] = -94.983936, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1191591084, states[0] = -7.374851, states[40]= 0.002804
Saving checkpoint... 
Iteration: 1204884277, states[0] = -94.978881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1218061847, states[0] = 8.086726, states[40]= 0.004699
Saving checkpoint... 
Iteration: 1231389649, states[0] = -94.980642, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1244574614, states[0] = 2.553777, states[40]= 0.004396
Saving checkpoint... 
Iteration: 1257894626, states[0] = -94.982193, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1270971683, states[0] = -94.999036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1284338234, states[0] = -94.959142, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1297718308, states[0] = -94.835290, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1311009977, states[0] = 22.351724, states[40]= 0.053123
Saving checkpoint... 
Iteration: 1324297874, states[0] = -94.932754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1337715740, states[0] = -94.830717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1351115396, states[0] = -28.510083, states[40]= 0.000566
Saving checkpoint... 
Iteration: 1364497981, states[0] = -95.002429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1377961307, states[0] = -94.997344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1391354775, states[0] = -94.967171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1404737399, states[0] = -94.866032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1418033581, states[0] = 17.936102, states[40]= 0.005396
Saving checkpoint... 
Iteration: 1431138035, states[0] = -49.927700, states[40]= 0.000029
Saving checkpoint... 
Iteration: 1444581462, states[0] = -1.026601, states[40]= 0.003984
Saving checkpoint... 
Iteration: 1458055958, states[0] = 10.342096, states[40]= 0.004749
Saving checkpoint... 
Iteration: 1471432308, states[0] = -94.991809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1484769206, states[0] = -94.906140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1498026736, states[0] = 19.755004, states[40]= 0.006316
Saving checkpoint... 
Iteration: 1511191448, states[0] = -21.492854, states[40]= 0.000916
Saving checkpoint... 
Iteration: 1524608073, states[0] = 24.330290, states[40]= 0.080332
Saving checkpoint... 
Iteration: 1537729270, states[0] = -95.193340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1550972955, states[0] = -95.248390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1564291010, states[0] = -23.263014, states[40]= 0.000821
Saving checkpoint... 
Iteration: 1577584465, states[0] = -95.129984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1590690703, states[0] = -23.219910, states[40]= 0.000823
Saving checkpoint... 
Iteration: 1603958030, states[0] = -95.010964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1617368699, states[0] = -2.408289, states[40]= 0.004289
Saving checkpoint... 
Iteration: 1630706779, states[0] = -95.179345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1643996353, states[0] = -95.279332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1657231270, states[0] = 17.008346, states[40]= 0.006609
Saving checkpoint... 
Iteration: 1670463908, states[0] = 0.805902, states[40]= 0.004807
Saving checkpoint... 
Iteration: 1683704205, states[0] = -37.438984, states[40]= 0.000195
Saving checkpoint... 
Iteration: 1697097528, states[0] = -95.280591, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1710469300, states[0] = -95.098326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1723717212, states[0] = -95.197596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1737026662, states[0] = 18.723138, states[40]= 0.007412
Saving checkpoint... 
Iteration: 1750228025, states[0] = 18.236089, states[40]= 0.007119
Saving checkpoint... 
Iteration: 1763532089, states[0] = -71.145487, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1776816734, states[0] = -95.196838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1790174886, states[0] = -7.478866, states[40]= 0.003175
Saving checkpoint... 
Iteration: 1803254456, states[0] = -94.942115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1816434038, states[0] = -95.033689, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1829668837, states[0] = -92.267882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1842995990, states[0] = -95.021183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1856134381, states[0] = -47.140162, states[40]= 0.000045
Saving checkpoint... 
Iteration: 1869366396, states[0] = -94.980488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1882748639, states[0] = -94.887289, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1896124048, states[0] = -36.578936, states[40]= 0.000219
Saving checkpoint... 
Iteration: 1909489319, states[0] = -95.003558, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1922661214, states[0] = -78.505162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1936036699, states[0] = 16.977806, states[40]= 0.005175
Saving checkpoint... 
Iteration: 1949343028, states[0] = -94.961909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1962694788, states[0] = -94.789250, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1975885560, states[0] = -94.979092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1989127998, states[0] = -40.034209, states[40]= 0.000134
Saving checkpoint... 
Iteration: 2002426421, states[0] = -94.990248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2015741362, states[0] = -94.871404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2029039662, states[0] = 16.047650, states[40]= 0.005028
Saving checkpoint... 
Iteration: 2042303201, states[0] = -94.936383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2055418160, states[0] = -94.988127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2068687880, states[0] = -94.762109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2081852759, states[0] = -94.965745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2095133599, states[0] = -45.447607, states[40]= 0.000059
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.877992
 - CaMKt in component CaMK (millimolar): 0.007123
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.490993
 - nass in component intracellular_ions (millimolar): 6.491053
 - ki in component intracellular_ions (millimolar): 145.486768
 - kss in component intracellular_ions (millimolar): 145.486750
 - cansr in component intracellular_ions (millimolar): 1.309698
 - cajsr in component intracellular_ions (millimolar): 1.270810
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003627
 - hf in component INa (dimensionless): 0.879586
 - hs in component INa (dimensionless): 0.879582
 - j in component INa (dimensionless): 0.879553
 - hsp in component INa (dimensionless): 0.725050
 - jp in component INa (dimensionless): 0.879534
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.707427
 - hLp in component INaL (dimensionless): 0.445839
 - a in component Ito (dimensionless): 0.000624
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.613530
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.687039
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.931750
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999870
 - jca in component ICaL (dimensionless): 0.999974
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001581
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.335954
 - xs1 in component IKs (dimensionless): 0.251856
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997343
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
03:31:28 (61416): called boinc_finish(0)

</stderr_txt>
]]>


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