𝕏

Task 55345663

Name HuVeMOp_20240629202752950406_ORdGradInc_k_25-Pieske_500-conf_925_0
Workunit 26280845
Created 29 Jun 2024, 18:31:23 UTC
Sent 29 Jun 2024, 23:11:55 UTC
Report deadline 2 Jul 2024, 23:11:55 UTC
Received 1 Jul 2024, 23:12:13 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 213632
Run time 1 hours 58 min 13 sec
CPU time 1 hours 34 min 34 sec
Validate state Valid
Credit 44.77
Device peak FLOPS 3.94 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.19 MB
Peak swap size 6.21 MB
Peak disk usage 0.17 MB

Stderr output

<core_client_version>7.20.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629202752950406_ORdGradInc_k_25-Pieske_500-conf_925.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629202752950406_ORdGradInc_k_25-Pieske_500-conf_925_0_r1001408907_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629202752950406_ORdGradInc_k_25-Pieske_500-conf_925_0_r1001408907_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 94.701819
     * GNaL_b in INaL: 0.004459
     * Gto_b in Ito: 0.077114
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030398
     * GKs_b in IKs: 0.001915
     * GK1_b in IK1: 0.175507
     * Gncx_b in INaCa_i: 0.000978
     * Pnak_b in INaK: 65.987849
     * GKb_b in IKb: 0.003738
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.026976
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 6000.000000
     * CL_0 in membrane: 500.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499750000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 13263895, states[0] = 22.956072, states[40]= 0.020949
Saving checkpoint... 
Iteration: 27018703, states[0] = 21.672726, states[40]= 0.010878
Saving checkpoint... 
Iteration: 40644658, states[0] = -87.074881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 54052386, states[0] = 4.362840, states[40]= 0.005525
Saving checkpoint... 
Iteration: 67619630, states[0] = -74.213357, states[40]= 0.000001
Saving checkpoint... 
Iteration: 81317627, states[0] = -8.406916, states[40]= 0.003162
Saving checkpoint... 
Iteration: 95055153, states[0] = 2.499039, states[40]= 0.005334
Saving checkpoint... 
Iteration: 105904161, states[0] = -87.110850, states[40]= 0.000000
Saving checkpoint... 
Iteration: 115698920, states[0] = -87.219172, states[40]= 0.000000
Saving checkpoint... 
Iteration: 127907666, states[0] = -87.121123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 140552219, states[0] = 4.523951, states[40]= 0.005539
Saving checkpoint... 
Iteration: 152981446, states[0] = -87.270465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 163437322, states[0] = -87.195359, states[40]= 0.000000
Saving checkpoint... 
Iteration: 172070013, states[0] = -11.017043, states[40]= 0.002534
Saving checkpoint... 
Iteration: 181450523, states[0] = -87.221766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 188820282, states[0] = -11.324008, states[40]= 0.002464
Saving checkpoint... 
Iteration: 194443428, states[0] = -87.207989, states[40]= 0.000000
Saving checkpoint... 
Iteration: 200067707, states[0] = -8.452301, states[40]= 0.003150
Saving checkpoint... 
Iteration: 207504778, states[0] = 28.237788, states[40]= 0.132972
Saving checkpoint... 
Iteration: 216538540, states[0] = 12.722975, states[40]= 0.006158
Saving checkpoint... 
Iteration: 223802311, states[0] = 4.465652, states[40]= 0.005533
Saving checkpoint... 
Iteration: 230197523, states[0] = -87.215994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 235770837, states[0] = 21.012952, states[40]= 0.009181
Saving checkpoint... 
Iteration: 241518488, states[0] = 21.821530, states[40]= 0.011013
Saving checkpoint... 
Iteration: 248081378, states[0] = -24.597071, states[40]= 0.000738
Saving checkpoint... 
Iteration: 256340265, states[0] = -35.164217, states[40]= 0.000254
Saving checkpoint... 
Iteration: 263553529, states[0] = 3.644293, states[40]= 0.005455
Saving checkpoint... 
Iteration: 269580671, states[0] = -23.747943, states[40]= 0.000791
Saving checkpoint... 
Iteration: 275789968, states[0] = 11.935478, states[40]= 0.006089
Saving checkpoint... 
Iteration: 286106716, states[0] = -55.133166, states[40]= 0.000013
Saving checkpoint... 
Iteration: 296501373, states[0] = 39.944322, states[40]= 0.065106
Saving checkpoint... 
Iteration: 305750387, states[0] = -38.139060, states[40]= 0.000002
Saving checkpoint... 
Iteration: 316786797, states[0] = 13.665703, states[40]= 0.006250
Saving checkpoint... 
Iteration: 329025712, states[0] = 19.070569, states[40]= 0.007443
Saving checkpoint... 
Iteration: 339630840, states[0] = -86.000973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 348415288, states[0] = -87.141881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 360265738, states[0] = 22.652195, states[40]= 0.015174
Saving checkpoint... 
Iteration: 373029493, states[0] = 17.359010, states[40]= 0.006842
Saving checkpoint... 
Iteration: 386229611, states[0] = -87.267658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 399409308, states[0] = -87.125296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 412860414, states[0] = -60.022230, states[40]= 0.000006
Saving checkpoint... 
Iteration: 426266877, states[0] = 22.323305, states[40]= 0.013078
Saving checkpoint... 
Iteration: 439821781, states[0] = -13.064995, states[40]= 0.002093
Saving checkpoint... 
Iteration: 453241061, states[0] = -87.281959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 466876573, states[0] = -83.599749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 480271694, states[0] = 20.696267, states[40]= 0.008731
Saving checkpoint... 
Iteration: 493926677, states[0] = -87.170668, states[40]= 0.000000
Saving checkpoint... 
Iteration: 507595285, states[0] = -41.103463, states[40]= 0.000114
Saving checkpoint... 
Iteration: 519756432, states[0] = 26.016967, states[40]= 0.099693
Saving checkpoint... 
Iteration: 529937704, states[0] = -87.195686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 540130067, states[0] = -85.731798, states[40]= 0.000000
Saving checkpoint... 
Iteration: 550350033, states[0] = -46.807054, states[40]= 0.000049
Saving checkpoint... 
Iteration: 560398026, states[0] = -87.087416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 570531732, states[0] = 16.276002, states[40]= 0.006610
Saving checkpoint... 
Iteration: 580679370, states[0] = -87.176956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 590765712, states[0] = 22.659534, states[40]= 0.015229
Saving checkpoint... 
Iteration: 600870652, states[0] = -75.744877, states[40]= 0.000000
Saving checkpoint... 
Iteration: 610754206, states[0] = 29.474277, states[40]= 0.141032
Saving checkpoint... 
Iteration: 620498651, states[0] = -87.290324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 630431552, states[0] = -87.181947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 640329806, states[0] = -22.706788, states[40]= 0.000861
Saving checkpoint... 
Iteration: 650397654, states[0] = -87.085585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 660193500, states[0] = -87.207582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 672957616, states[0] = -87.233868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 686593430, states[0] = -38.902795, states[40]= 0.000155
Saving checkpoint... 
Iteration: 700306418, states[0] = 1.602589, states[40]= 0.005224
Saving checkpoint... 
Iteration: 714063978, states[0] = -4.669732, states[40]= 0.004077
Saving checkpoint... 
Iteration: 727492955, states[0] = -87.283857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 741169340, states[0] = -87.152102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 754738866, states[0] = -87.279010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 768270156, states[0] = 21.256829, states[40]= 0.009608
Saving checkpoint... 
Iteration: 781661262, states[0] = -87.130380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 795289918, states[0] = 11.963607, states[40]= 0.006092
Saving checkpoint... 
Iteration: 808984542, states[0] = -87.273608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 822811393, states[0] = -2.335654, states[40]= 0.004582
Saving checkpoint... 
Iteration: 836589083, states[0] = -33.766580, states[40]= 0.000302
Saving checkpoint... 
Iteration: 847424880, states[0] = -87.165912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 857609408, states[0] = -58.660521, states[40]= 0.000008
Saving checkpoint... 
Iteration: 867616603, states[0] = -69.129639, states[40]= 0.000001
Saving checkpoint... 
Iteration: 877495105, states[0] = -87.286134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 887319737, states[0] = -10.699418, states[40]= 0.002607
Saving checkpoint... 
Iteration: 897005523, states[0] = 27.037376, states[40]= 0.118646
Saving checkpoint... 
Iteration: 906736980, states[0] = -87.276543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 916516379, states[0] = 22.469817, states[40]= 0.013916
Saving checkpoint... 
Iteration: 926495536, states[0] = -87.286562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 936469629, states[0] = -87.252887, states[40]= 0.000000
Saving checkpoint... 
Iteration: 946429846, states[0] = -87.177656, states[40]= 0.000000
Saving checkpoint... 
Iteration: 956438200, states[0] = -87.196268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 966481626, states[0] = -87.269678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 976256774, states[0] = 25.723366, states[40]= 0.092795
Saving checkpoint... 
Iteration: 986099895, states[0] = -46.638464, states[40]= 0.000050
Saving checkpoint... 
Iteration: 998241607, states[0] = -87.281992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1011632485, states[0] = -86.411170, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1025050620, states[0] = 5.574884, states[40]= 0.005628
Saving checkpoint... 
Iteration: 1038563392, states[0] = -4.120175, states[40]= 0.004202
Saving checkpoint... 
Iteration: 1052481461, states[0] = -87.269366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1066272705, states[0] = 20.308547, states[40]= 0.008300
Saving checkpoint... 
Iteration: 1079979273, states[0] = -87.266430, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1093805045, states[0] = 2.591339, states[40]= 0.005344
Saving checkpoint... 
Iteration: 1107634071, states[0] = -86.660037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1121275228, states[0] = 19.278088, states[40]= 0.007550
Saving checkpoint... 
Iteration: 1133381925, states[0] = -86.291804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1144152271, states[0] = -87.103025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1155815627, states[0] = -6.280606, states[40]= 0.003690
Saving checkpoint... 
Iteration: 1166436055, states[0] = -87.191406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1176407518, states[0] = -87.119249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1186229431, states[0] = -87.266524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1195889499, states[0] = -86.994171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1205799267, states[0] = 6.438218, states[40]= 0.005694
Saving checkpoint... 
Iteration: 1213962877, states[0] = -87.242046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1220047926, states[0] = 7.275342, states[40]= 0.005755
Saving checkpoint... 
Iteration: 1226272773, states[0] = 20.281984, states[40]= 0.008275
Saving checkpoint... 
Iteration: 1234063305, states[0] = -4.039455, states[40]= 0.004221
Saving checkpoint... 
Iteration: 1240779757, states[0] = 17.234218, states[40]= 0.006811
Saving checkpoint... 
Iteration: 1247248095, states[0] = -87.289024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1252941445, states[0] = -87.202734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1261996657, states[0] = -87.287433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1271563018, states[0] = -3.775726, states[40]= 0.004279
Saving checkpoint... 
Iteration: 1281274284, states[0] = 19.673680, states[40]= 0.007788
Saving checkpoint... 
Iteration: 1292213100, states[0] = -87.242319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1305709123, states[0] = -87.235730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1319286827, states[0] = 13.650189, states[40]= 0.006248
Saving checkpoint... 
Iteration: 1332873103, states[0] = -79.539465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1346607970, states[0] = -56.756360, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1360597462, states[0] = -43.701460, states[40]= 0.000078
Saving checkpoint... 
Iteration: 1374322698, states[0] = -14.147556, states[40]= 0.001885
Saving checkpoint... 
Iteration: 1387665531, states[0] = -87.141363, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1401130723, states[0] = -85.961680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1414595003, states[0] = -40.766536, states[40]= 0.000120
Saving checkpoint... 
Iteration: 1428195158, states[0] = -87.210029, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1441906183, states[0] = -87.115000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1455579638, states[0] = -22.503154, states[40]= 0.000875
Saving checkpoint... 
Iteration: 1468880498, states[0] = -85.886645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1482443876, states[0] = -87.207416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1496116294, states[0] = -68.637876, states[40]= 0.000002
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -87.166541
 - CaMKt in component CaMK (millimolar): 0.019959
 - cass in component intracellular_ions (millimolar): 0.000095
 - nai in component intracellular_ions (millimolar): 6.881980
 - nass in component intracellular_ions (millimolar): 6.882079
 - ki in component intracellular_ions (millimolar): 145.072210
 - kss in component intracellular_ions (millimolar): 145.072186
 - cansr in component intracellular_ions (millimolar): 1.437482
 - cajsr in component intracellular_ions (millimolar): 1.216866
 - cai in component intracellular_ions (millimolar): 0.000094
 - m in component INa (dimensionless): 0.007888
 - hf in component INa (dimensionless): 0.672926
 - hs in component INa (dimensionless): 0.672826
 - j in component INa (dimensionless): 0.672139
 - hsp in component INa (dimensionless): 0.425865
 - jp in component INa (dimensionless): 0.670159
 - mL in component INaL (dimensionless): 0.000215
 - hL in component INaL (dimensionless): 0.382097
 - hLp in component INaL (dimensionless): 0.178050
 - a in component Ito (dimensionless): 0.001050
 - iF in component Ito (dimensionless): 0.999495
 - iS in component Ito (dimensionless): 0.290798
 - ap in component Ito (dimensionless): 0.000535
 - iFp in component Ito (dimensionless): 0.999495
 - iSp in component Ito (dimensionless): 0.337342
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.854705
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.990760
 - jca in component ICaL (dimensionless): 0.991200
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004282
 - xrf in component IKr (dimensionless): 0.001911
 - xrs in component IKr (dimensionless): 0.674255
 - xs1 in component IKs (dimensionless): 0.386442
 - xs2 in component IKs (dimensionless): 0.000219
 - xk1 in component IK1 (dimensionless): 0.996943
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
16:59:44 (34256): called boinc_finish(0)

</stderr_txt>
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