𝕏

Task 55340249

Name HuVeMOp_20240629202752950406_ORdGradInc_k_25-Pueyo_APDR-conf_502_0
Workunit 26278143
Created 29 Jun 2024, 18:28:16 UTC
Sent 29 Jun 2024, 22:48:39 UTC
Report deadline 3 Jul 2024, 8:24:39 UTC
Received 2 Jul 2024, 10:57:42 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 226324
Run time 2 hours 48 min 11 sec
CPU time 2 hours 31 min 46 sec
Validate state Valid
Credit 62.07
Device peak FLOPS 4.68 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.40 MB
Peak swap size 3.82 MB
Peak disk usage 0.30 MB

Stderr output

<core_client_version>7.18.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629202752950406_ORdGradInc_k_25-Pueyo_APDR-conf_502.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629202752950406_ORdGradInc_k_25-Pueyo_APDR-conf_502_0_r340078950_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629202752950406_ORdGradInc_k_25-Pueyo_APDR-conf_502_0_r340078950_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 102.156581
     * GNaL_b in INaL: 0.006522
     * Gto_b in Ito: 0.094918
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032193
     * GKs_b in IKs: 0.001788
     * GK1_b in IK1: 0.158088
     * Gncx_b in INaCa_i: 0.000957
     * Pnak_b in INaK: 66.162740
     * GKb_b in IKb: 0.003857
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.050298
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 14471564, states[0] = -95.009150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 28524188, states[0] = 19.703100, states[40]= 0.006692
Saving checkpoint... 
Iteration: 42046821, states[0] = 12.898380, states[40]= 0.004794
Saving checkpoint... 
Iteration: 55580141, states[0] = -1.813401, states[40]= 0.003910
Saving checkpoint... 
Iteration: 69757409, states[0] = -94.858924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 83440011, states[0] = -94.958295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 97758041, states[0] = -94.854817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 111087951, states[0] = -6.796580, states[40]= 0.002959
Saving checkpoint... 
Iteration: 124283122, states[0] = -94.879708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 137737734, states[0] = -94.824614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 151900220, states[0] = -94.943519, states[40]= 0.000000
Saving checkpoint... 
Iteration: 167261406, states[0] = -94.855503, states[40]= 0.000000
Saving checkpoint... 
Iteration: 180953943, states[0] = -94.955514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 194892906, states[0] = -94.940694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 208728595, states[0] = -94.809177, states[40]= 0.000000
Saving checkpoint... 
Iteration: 221421363, states[0] = -94.948469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 234452471, states[0] = -94.954950, states[40]= 0.000000
Saving checkpoint... 
Iteration: 248202176, states[0] = -94.760497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 261760455, states[0] = -94.853837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 274738511, states[0] = -94.824507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 287579044, states[0] = -0.780426, states[40]= 0.004054
Saving checkpoint... 
Iteration: 301398163, states[0] = -94.942032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 315159176, states[0] = -81.308193, states[40]= 0.000000
Saving checkpoint... 
Iteration: 329134146, states[0] = -49.587563, states[40]= 0.000031
Saving checkpoint... 
Iteration: 342717345, states[0] = -94.789517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 356470902, states[0] = -94.957837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 369957967, states[0] = -94.955746, states[40]= 0.000000
Saving checkpoint... 
Iteration: 383405209, states[0] = -94.944020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 396124093, states[0] = -39.370847, states[40]= 0.000149
Saving checkpoint... 
Iteration: 410813717, states[0] = -94.902482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 425694492, states[0] = -94.743924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 439324144, states[0] = -94.909280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 452485120, states[0] = -94.959771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 467279938, states[0] = -94.874663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 480380120, states[0] = -94.935944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 493911009, states[0] = -94.945530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 507762798, states[0] = -94.856379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 520939363, states[0] = -94.952152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 533646599, states[0] = -63.363551, states[40]= 0.000003
Saving checkpoint... 
Iteration: 547287675, states[0] = -94.881840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 560579105, states[0] = -0.815197, states[40]= 0.004049
Saving checkpoint... 
Iteration: 575298199, states[0] = -94.890782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 588838511, states[0] = -94.917475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 601515589, states[0] = 21.310750, states[40]= 0.015650
Saving checkpoint... 
Iteration: 614280040, states[0] = -94.874652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 627879257, states[0] = -94.935523, states[40]= 0.000000
Saving checkpoint... 
Iteration: 641177370, states[0] = -94.567706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 654712005, states[0] = -94.779398, states[40]= 0.000000
Saving checkpoint... 
Iteration: 669695541, states[0] = -94.746120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 683470548, states[0] = -94.957539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 696889996, states[0] = -94.939164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 709525803, states[0] = 19.639048, states[40]= 0.006288
Saving checkpoint... 
Iteration: 722462353, states[0] = -94.956218, states[40]= 0.000000
Saving checkpoint... 
Iteration: 735363209, states[0] = -94.929164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 748127004, states[0] = -42.231220, states[40]= 0.000098
Saving checkpoint... 
Iteration: 760863220, states[0] = -94.929149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 774822632, states[0] = -94.908085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 787580172, states[0] = -1.442667, states[40]= 0.003958
Saving checkpoint... 
Iteration: 800918460, states[0] = -94.947224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 814016296, states[0] = 21.237548, states[40]= 0.013938
Saving checkpoint... 
Iteration: 826687670, states[0] = -94.724022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 840350626, states[0] = -94.923431, states[40]= 0.000000
Saving checkpoint... 
Iteration: 853627099, states[0] = -42.325867, states[40]= 0.000096
Saving checkpoint... 
Iteration: 866558386, states[0] = 8.863678, states[40]= 0.004716
Saving checkpoint... 
Iteration: 881042708, states[0] = 14.628734, states[40]= 0.004861
Saving checkpoint... 
Iteration: 894953019, states[0] = -94.954489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 909981443, states[0] = -94.958938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 922842434, states[0] = -94.919296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 935887591, states[0] = -94.938192, states[40]= 0.000000
Saving checkpoint... 
Iteration: 949714826, states[0] = -94.784450, states[40]= 0.000000
Saving checkpoint... 
Iteration: 963220967, states[0] = -94.795510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 976969035, states[0] = -94.957090, states[40]= 0.000000
Saving checkpoint... 
Iteration: 989775189, states[0] = -94.869536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1004469419, states[0] = -94.957128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1018472256, states[0] = -94.957547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1034992463, states[0] = -94.960271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1048373885, states[0] = -94.933216, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1061258491, states[0] = -94.850846, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1073978921, states[0] = -94.958468, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1087851902, states[0] = -94.923852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1101710926, states[0] = -94.777017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1115729893, states[0] = -94.810463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1130068192, states[0] = 4.733303, states[40]= 0.004576
Saving checkpoint... 
Iteration: 1143451708, states[0] = -94.954068, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1155964001, states[0] = -94.956164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1170452270, states[0] = -94.954150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1183294008, states[0] = -94.886875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1196253232, states[0] = -94.844176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1209658903, states[0] = -80.846100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1222387881, states[0] = -94.938076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1235794577, states[0] = -94.887314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1248709400, states[0] = -94.773984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1262262610, states[0] = -94.855597, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1275472457, states[0] = -94.957386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1287966534, states[0] = -94.956470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1300887447, states[0] = -94.937873, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1313532768, states[0] = 17.818186, states[40]= 0.005330
Saving checkpoint... 
Iteration: 1326778123, states[0] = -94.872239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1339190272, states[0] = -94.732445, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1352242971, states[0] = -94.830177, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1365021023, states[0] = 20.589577, states[40]= 0.008122
Saving checkpoint... 
Iteration: 1377799979, states[0] = -94.891607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1391261899, states[0] = -94.854669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1404556778, states[0] = 9.493097, states[40]= 0.004726
Saving checkpoint... 
Iteration: 1418309779, states[0] = -94.898964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1432528753, states[0] = 18.922943, states[40]= 0.005762
Saving checkpoint... 
Iteration: 1445236305, states[0] = -94.820288, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1458876479, states[0] = -94.933887, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1471779743, states[0] = -94.873724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1486458912, states[0] = -94.955077, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1499649834, states[0] = -67.340882, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1512780255, states[0] = -95.047466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1525868726, states[0] = -2.799482, states[40]= 0.004224
Saving checkpoint... 
Iteration: 1539336292, states[0] = 14.706432, states[40]= 0.006025
Saving checkpoint... 
Iteration: 1553693123, states[0] = -95.236084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1566714149, states[0] = -51.455756, states[40]= 0.000025
Saving checkpoint... 
Iteration: 1580223657, states[0] = -63.542826, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1594479923, states[0] = -95.237186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1609131782, states[0] = -95.188071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1621728359, states[0] = -95.184158, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1634286827, states[0] = -95.109888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1647386588, states[0] = -21.576485, states[40]= 0.000927
Saving checkpoint... 
Iteration: 1663806795, states[0] = 24.725049, states[40]= 0.107823
Saving checkpoint... 
Iteration: 1677858848, states[0] = -95.222009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1690839075, states[0] = 13.159178, states[40]= 0.005854
Saving checkpoint... 
Iteration: 1704627723, states[0] = 17.889330, states[40]= 0.006955
Saving checkpoint... 
Iteration: 1716913519, states[0] = 21.841211, states[40]= 0.024689
Saving checkpoint... 
Iteration: 1730347706, states[0] = -95.210271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1743529079, states[0] = -95.186708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1757030440, states[0] = -95.188602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1770431271, states[0] = -75.290096, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1783296692, states[0] = -32.344587, states[40]= 0.000370
Saving checkpoint... 
Iteration: 1797634975, states[0] = 14.980928, states[40]= 0.006109
Saving checkpoint... 
Iteration: 1810193675, states[0] = -94.788340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1822904113, states[0] = -94.981536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1837144777, states[0] = -63.236331, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1851095730, states[0] = -14.031440, states[40]= 0.001585
Saving checkpoint... 
Iteration: 1866454657, states[0] = -94.965002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1879815486, states[0] = -94.910006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1892461073, states[0] = -94.960198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1905575721, states[0] = 0.966502, states[40]= 0.004274
Saving checkpoint... 
Iteration: 1918969343, states[0] = -94.958728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1932510087, states[0] = 21.932728, states[40]= 0.051076
Saving checkpoint... 
Iteration: 1945094143, states[0] = -11.835367, states[40]= 0.001940
Saving checkpoint... 
Iteration: 1957571191, states[0] = 3.319093, states[40]= 0.004486
Saving checkpoint... 
Iteration: 1970935966, states[0] = -94.950815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1983696536, states[0] = -94.747621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1996277819, states[0] = -94.871613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2009593193, states[0] = -10.966554, states[40]= 0.002101
Saving checkpoint... 
Iteration: 2022746471, states[0] = -94.834616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2037270563, states[0] = -94.863910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2050577716, states[0] = -0.026921, states[40]= 0.004154
Saving checkpoint... 
Iteration: 2064940862, states[0] = -94.951267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2077557963, states[0] = 9.030184, states[40]= 0.004719
Saving checkpoint... 
Iteration: 2090231528, states[0] = -94.812302, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.836183
 - CaMKt in component CaMK (millimolar): 0.007294
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.734617
 - nass in component intracellular_ions (millimolar): 6.734676
 - ki in component intracellular_ions (millimolar): 145.238969
 - kss in component intracellular_ions (millimolar): 145.238949
 - cansr in component intracellular_ions (millimolar): 1.325343
 - cajsr in component intracellular_ions (millimolar): 1.286711
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003643
 - hf in component INa (dimensionless): 0.878857
 - hs in component INa (dimensionless): 0.878852
 - j in component INa (dimensionless): 0.878823
 - hsp in component INa (dimensionless): 0.723678
 - jp in component INa (dimensionless): 0.878804
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.707263
 - hLp in component INaL (dimensionless): 0.447296
 - a in component Ito (dimensionless): 0.000626
 - iF in component Ito (dimensionless): 0.999868
 - iS in component Ito (dimensionless): 0.617080
 - ap in component Ito (dimensionless): 0.000319
 - iFp in component Ito (dimensionless): 0.999868
 - iSp in component Ito (dimensionless): 0.691292
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.934252
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999881
 - jca in component ICaL (dimensionless): 0.999976
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001638
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.327520
 - xs1 in component IKs (dimensionless): 0.246421
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997354
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
12:57:40 (28052): called boinc_finish(0)

</stderr_txt>
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