𝕏

Task 55339955

Name HuVeMOp_20240629202752950406_ORdGradInc_k_25-Pueyo_APDR-conf_600_0
Workunit 26277996
Created 29 Jun 2024, 18:28:06 UTC
Sent 29 Jun 2024, 22:18:23 UTC
Report deadline 3 Jul 2024, 7:54:23 UTC
Received 30 Jun 2024, 18:46:01 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 233300
Run time 1 hours 35 min 38 sec
CPU time 1 hours 34 min 44 sec
Validate state Valid
Credit 58.36
Device peak FLOPS 5.28 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.30 MB
Peak swap size 6.24 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629202752950406_ORdGradInc_k_25-Pueyo_APDR-conf_600.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629202752950406_ORdGradInc_k_25-Pueyo_APDR-conf_600_0_r711397314_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629202752950406_ORdGradInc_k_25-Pueyo_APDR-conf_600_0_r711397314_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 93.342627
     * GNaL_b in INaL: 0.007249
     * Gto_b in Ito: 0.087531
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030529
     * GKs_b in IKs: 0.001914
     * GK1_b in IK1: 0.179668
     * Gncx_b in INaCa_i: 0.000963
     * Pnak_b in INaK: 71.913311
     * GKb_b in IKb: 0.003700
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036077
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 24314087, states[0] = -95.031099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48501003, states[0] = 45.871410, states[40]= 0.032352
Saving checkpoint... 
Iteration: 72818411, states[0] = -94.995749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 97190779, states[0] = -94.830542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 121483934, states[0] = -95.039251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 145255104, states[0] = -94.932001, states[40]= 0.000000
Saving checkpoint... 
Iteration: 169634873, states[0] = -43.693602, states[40]= 0.000084
Saving checkpoint... 
Iteration: 193931446, states[0] = -95.028460, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629202752950406_ORdGradInc_k_25-Pueyo_APDR-conf_600.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629202752950406_ORdGradInc_k_25-Pueyo_APDR-conf_600_0_r711397314_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629202752950406_ORdGradInc_k_25-Pueyo_APDR-conf_600_0_r711397314_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 93.342627
     * GNaL_b in INaL: 0.007249
     * Gto_b in Ito: 0.087531
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030529
     * GKs_b in IKs: 0.001914
     * GK1_b in IK1: 0.179668
     * Gncx_b in INaCa_i: 0.000963
     * Pnak_b in INaK: 71.913311
     * GKb_b in IKb: 0.003700
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036077
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 193931446
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -95.028460 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 216403916, states[0] = -95.021716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 239584275, states[0] = -1.236951, states[40]= 0.003980
Saving checkpoint... 
Iteration: 263803222, states[0] = -94.975522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 287969348, states[0] = -95.034865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 311751522, states[0] = -94.926471, states[40]= 0.000000
Saving checkpoint... 
Iteration: 335760779, states[0] = -94.937224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 360102192, states[0] = -14.413877, states[40]= 0.001517
Saving checkpoint... 
Iteration: 384201198, states[0] = -94.848417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 408453898, states[0] = -95.032311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 432179575, states[0] = -94.621413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 455598716, states[0] = -11.462247, states[40]= 0.001994
Saving checkpoint... 
Iteration: 479177222, states[0] = -94.386071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 503356285, states[0] = -95.005026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 527574683, states[0] = 3.721335, states[40]= 0.004520
Saving checkpoint... 
Iteration: 551521123, states[0] = 21.834236, states[40]= 0.008198
Saving checkpoint... 
Iteration: 575605334, states[0] = -17.142259, states[40]= 0.001203
Saving checkpoint... 
Iteration: 599723032, states[0] = -94.886219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 624015299, states[0] = 22.579434, states[40]= 0.016482
Saving checkpoint... 
Iteration: 648259107, states[0] = -94.935127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 672429433, states[0] = -95.027437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 696521057, states[0] = 21.845121, states[40]= 0.008239
Saving checkpoint... 
Iteration: 720664349, states[0] = -81.337683, states[40]= 0.000000
Saving checkpoint... 
Iteration: 744791934, states[0] = -94.966539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 768882811, states[0] = -95.014846, states[40]= 0.000000
Saving checkpoint... 
Iteration: 793209536, states[0] = -94.863318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 817346456, states[0] = -95.000400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 841707308, states[0] = -94.859309, states[40]= 0.000000
Saving checkpoint... 
Iteration: 865926392, states[0] = -95.026639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 890311958, states[0] = -94.981069, states[40]= 0.000000
Saving checkpoint... 
Iteration: 914631705, states[0] = -40.573208, states[40]= 0.000133
Saving checkpoint... 
Iteration: 939051588, states[0] = 12.986680, states[40]= 0.004803
Saving checkpoint... 
Iteration: 963140882, states[0] = -49.811248, states[40]= 0.000032
Saving checkpoint... 
Iteration: 987317232, states[0] = -94.984389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1011411248, states[0] = -95.022951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1035716508, states[0] = -94.875196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1060036254, states[0] = 18.128622, states[40]= 0.005160


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629202752950406_ORdGradInc_k_25-Pueyo_APDR-conf_600.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629202752950406_ORdGradInc_k_25-Pueyo_APDR-conf_600_0_r711397314_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629202752950406_ORdGradInc_k_25-Pueyo_APDR-conf_600_0_r711397314_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 93.342627
     * GNaL_b in INaL: 0.007249
     * Gto_b in Ito: 0.087531
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030529
     * GKs_b in IKs: 0.001914
     * GK1_b in IK1: 0.179668
     * Gncx_b in INaCa_i: 0.000963
     * Pnak_b in INaK: 71.913311
     * GKb_b in IKb: 0.003700
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036077
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1060036254
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: 18.128622 (After loading)
 - states[40]: 0.005160 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1082891552, states[0] = -95.017407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1105974668, states[0] = -95.035038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1130029641, states[0] = 20.004560, states[40]= 0.005735
Saving checkpoint... 
Iteration: 1154233488, states[0] = -94.901788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1177961152, states[0] = -95.032964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1202104904, states[0] = -16.766991, states[40]= 0.001239
Saving checkpoint... 
Iteration: 1226393198, states[0] = -95.017805, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1250875520, states[0] = -95.012002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1275178906, states[0] = -94.571246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1298956006, states[0] = -95.032039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1319681353, states[0] = -94.709513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1343630034, states[0] = -38.994439, states[40]= 0.000167
Saving checkpoint... 
Iteration: 1367725581, states[0] = -94.889703, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1368729990, states[0] = -94.896462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1395520727, states[0] = 21.898694, states[40]= 0.008453
Saving checkpoint... 
Iteration: 1420065135, states[0] = 7.861714, states[40]= 0.004725
Saving checkpoint... 
Iteration: 1444366946, states[0] = -95.008690, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1468537566, states[0] = 17.723649, states[40]= 0.005091
Saving checkpoint... 
Iteration: 1492778117, states[0] = -94.954033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1516795872, states[0] = -95.248651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1540635065, states[0] = -71.012927, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1564548859, states[0] = 10.148673, states[40]= 0.005572
Saving checkpoint... 
Iteration: 1588418594, states[0] = -95.202875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1612337602, states[0] = -77.453308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1636424184, states[0] = -95.213632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1660483953, states[0] = -95.274384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1684530889, states[0] = 17.950083, states[40]= 0.006598
Saving checkpoint... 
Iteration: 1708576147, states[0] = -6.816379, states[40]= 0.003356
Saving checkpoint... 
Iteration: 1732482536, states[0] = -95.273588, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1756270369, states[0] = -2.265812, states[40]= 0.004355
Saving checkpoint... 
Iteration: 1780142958, states[0] = -95.237640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1804209751, states[0] = -94.899192, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1828149303, states[0] = -61.630387, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1852015102, states[0] = 22.489055, states[40]= 0.016956
Saving checkpoint... 
Iteration: 1876027860, states[0] = 20.373908, states[40]= 0.005985
Saving checkpoint... 
Iteration: 1899869298, states[0] = -95.012084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1923779650, states[0] = -94.956493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1947748282, states[0] = -94.921914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1971591405, states[0] = -5.811601, states[40]= 0.003147
Saving checkpoint... 
Iteration: 1995382060, states[0] = -95.013826, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2019417787, states[0] = -95.023861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2043364211, states[0] = -95.007169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2067232584, states[0] = -94.899770, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2091202242, states[0] = -94.849098, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.913314
 - CaMKt in component CaMK (millimolar): 0.007311
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.582348
 - nass in component intracellular_ions (millimolar): 6.582408
 - ki in component intracellular_ions (millimolar): 145.392041
 - kss in component intracellular_ions (millimolar): 145.392022
 - cansr in component intracellular_ions (millimolar): 1.323508
 - cajsr in component intracellular_ions (millimolar): 1.284203
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003614
 - hf in component INa (dimensionless): 0.880200
 - hs in component INa (dimensionless): 0.880195
 - j in component INa (dimensionless): 0.880168
 - hsp in component INa (dimensionless): 0.726206
 - jp in component INa (dimensionless): 0.880149
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.708043
 - hLp in component INaL (dimensionless): 0.446068
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.611205
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.684249
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.927450
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999857
 - jca in component ICaL (dimensionless): 0.999972
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001642
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.337861
 - xs1 in component IKs (dimensionless): 0.258672
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997334
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
21:18:13 (7956): called boinc_finish(0)

</stderr_txt>
]]>