𝕏

Task 55337022

Name HuVeMOp_20240629201600757918_ORdGradInc_k_25-Pueyo_APDR-conf_469_0
Workunit 26276530
Created 29 Jun 2024, 18:25:47 UTC
Sent 29 Jun 2024, 21:30:09 UTC
Report deadline 3 Jul 2024, 7:06:09 UTC
Received 1 Jul 2024, 2:29:22 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 240807
Run time 2 hours 19 min 58 sec
CPU time 2 hours 7 min 41 sec
Validate state Valid
Credit 57.26
Device peak FLOPS 4.75 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.23 MB
Peak swap size 5.29 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629201600757918_ORdGradInc_k_25-Pueyo_APDR-conf_469.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629201600757918_ORdGradInc_k_25-Pueyo_APDR-conf_469_0_r780311779_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629201600757918_ORdGradInc_k_25-Pueyo_APDR-conf_469_0_r780311779_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 109.761310
     * GNaL_b in INaL: 0.005942
     * Gto_b in Ito: 0.080145
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031878
     * GKs_b in IKs: 0.002133
     * GK1_b in IK1: 0.181370
     * Gncx_b in INaCa_i: 0.000971
     * Pnak_b in INaK: 75.197261
     * GKb_b in IKb: 0.003693
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.034235
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 16981346, states[0] = -95.149724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 32234606, states[0] = -94.997588, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48600783, states[0] = -22.891529, states[40]= 0.000797
Saving checkpoint... 
Iteration: 64515234, states[0] = 22.426611, states[40]= 0.018602
Saving checkpoint... 
Iteration: 80542454, states[0] = 14.336986, states[40]= 0.005309
Saving checkpoint... 
Iteration: 97120936, states[0] = -41.240976, states[40]= 0.000105
Saving checkpoint... 
Iteration: 115544482, states[0] = 13.671183, states[40]= 0.005232
Saving checkpoint... 
Iteration: 133477327, states[0] = -95.073981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 151987909, states[0] = -95.074428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 170261831, states[0] = -94.983132, states[40]= 0.000000
Saving checkpoint... 
Iteration: 188471297, states[0] = -95.071612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 206460982, states[0] = -95.069996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 224442061, states[0] = -95.066837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 242458172, states[0] = -95.069416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 260215999, states[0] = -94.924031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 277847352, states[0] = -95.039891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 295910327, states[0] = -95.060180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 313889406, states[0] = -95.054697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 332250402, states[0] = -94.970254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 350430689, states[0] = -95.064531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 368258793, states[0] = -94.979291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 386451095, states[0] = -95.068154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 403609756, states[0] = -29.755147, states[40]= 0.000470
Saving checkpoint... 
Iteration: 420190506, states[0] = -94.879156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 437137887, states[0] = -59.600647, states[40]= 0.000006
Saving checkpoint... 
Iteration: 454664176, states[0] = -94.306027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 472289066, states[0] = -95.006152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 489741636, states[0] = -94.959824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 507283338, states[0] = -95.001654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 524882034, states[0] = -95.052373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 542914037, states[0] = -95.060889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 560705088, states[0] = -94.905720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 578793701, states[0] = -95.009530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 596395158, states[0] = -95.056139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 614074002, states[0] = 0.566818, states[40]= 0.004362
Saving checkpoint... 
Iteration: 631392858, states[0] = -95.055485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 649442967, states[0] = -95.066633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 666936672, states[0] = -95.065489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 685145635, states[0] = -69.978583, states[40]= 0.000001
Saving checkpoint... 
Iteration: 702550356, states[0] = 11.423286, states[40]= 0.005080
Saving checkpoint... 
Iteration: 719644862, states[0] = -68.820548, states[40]= 0.000001
Saving checkpoint... 
Iteration: 737212739, states[0] = -94.918484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 755405708, states[0] = -95.058788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 773051670, states[0] = 10.894215, states[40]= 0.005055
Saving checkpoint... 
Iteration: 790320624, states[0] = -95.026521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 807688832, states[0] = -94.875698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 824956334, states[0] = -95.068733, states[40]= 0.000000
Saving checkpoint... 
Iteration: 842247132, states[0] = -94.966210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 859104338, states[0] = -24.543998, states[40]= 0.000718
Saving checkpoint... 
Iteration: 875347379, states[0] = -95.039538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 891083081, states[0] = -5.271577, states[40]= 0.003363
Saving checkpoint... 
Iteration: 907979851, states[0] = -95.071947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 924336401, states[0] = -95.034555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 941229553, states[0] = -94.943732, states[40]= 0.000000
Saving checkpoint... 
Iteration: 957903726, states[0] = -95.058178, states[40]= 0.000000
Saving checkpoint... 
Iteration: 974075749, states[0] = -0.436039, states[40]= 0.004228
Saving checkpoint... 
Iteration: 990316092, states[0] = -95.023836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1005804091, states[0] = -95.016437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1021275910, states[0] = -94.995151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1037157324, states[0] = -90.216183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1052612973, states[0] = -32.870927, states[40]= 0.000332
Saving checkpoint... 
Iteration: 1068829096, states[0] = -95.030872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1085876208, states[0] = -95.050208, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1101821685, states[0] = -95.026928, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1117539862, states[0] = 15.481233, states[40]= 0.005430
Saving checkpoint... 
Iteration: 1133564329, states[0] = 5.458125, states[40]= 0.004805
Saving checkpoint... 
Iteration: 1149299504, states[0] = -95.013289, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1165136760, states[0] = -58.244598, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1180881341, states[0] = -95.051785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1196782853, states[0] = -95.000869, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1212919160, states[0] = -95.061652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1229072818, states[0] = 1.221251, states[40]= 0.004441
Saving checkpoint... 
Iteration: 1245202565, states[0] = -94.900909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1261327611, states[0] = -95.029998, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1277341062, states[0] = -95.036522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1292984568, states[0] = -95.072300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1304747564, states[0] = -94.966448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1320428953, states[0] = -95.063633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1336110955, states[0] = -30.913310, states[40]= 0.000416
Saving checkpoint... 
Iteration: 1352266172, states[0] = -94.986076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1367454144, states[0] = -95.068082, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1382431033, states[0] = -95.064008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1398081032, states[0] = -3.803213, states[40]= 0.003659
Saving checkpoint... 
Iteration: 1414367689, states[0] = -95.047133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1430875972, states[0] = -95.049934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1447416650, states[0] = -95.060965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1463815513, states[0] = -95.023229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1480133609, states[0] = -54.560466, states[40]= 0.000013
Saving checkpoint... 
Iteration: 1496803958, states[0] = -95.016070, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1513600357, states[0] = -36.474791, states[40]= 0.000205
Saving checkpoint... 
Iteration: 1529983045, states[0] = -95.288393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1546605162, states[0] = -43.746367, states[40]= 0.000075
Saving checkpoint... 
Iteration: 1563052835, states[0] = 6.012862, states[40]= 0.005507
Saving checkpoint... 
Iteration: 1579148890, states[0] = -95.279157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1595457571, states[0] = 3.075045, states[40]= 0.005223
Saving checkpoint... 
Iteration: 1612262225, states[0] = -0.013429, states[40]= 0.004816
Saving checkpoint... 
Iteration: 1628294510, states[0] = -95.211173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1643548017, states[0] = -95.053172, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1659170354, states[0] = -95.163683, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1675810557, states[0] = 24.390482, states[40]= 0.047832
Saving checkpoint... 
Iteration: 1691270145, states[0] = -95.163398, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1707334494, states[0] = 15.320361, states[40]= 0.006725
Saving checkpoint... 
Iteration: 1723058584, states[0] = -95.135054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1738180225, states[0] = -95.309087, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1754285285, states[0] = -95.194993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1770058318, states[0] = 2.536938, states[40]= 0.005164
Saving checkpoint... 
Iteration: 1786065472, states[0] = -95.152675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1801902440, states[0] = -95.109289, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1818079781, states[0] = -4.458283, states[40]= 0.003580
Saving checkpoint... 
Iteration: 1833212185, states[0] = -94.938227, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1848149822, states[0] = -79.141759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1863463345, states[0] = -95.077497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1878425981, states[0] = -95.067957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1894392387, states[0] = -95.057841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1909555088, states[0] = 9.447828, states[40]= 0.004997
Saving checkpoint... 
Iteration: 1925409132, states[0] = -95.060175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1941699460, states[0] = -94.895703, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1956975664, states[0] = -95.071262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1972319479, states[0] = -95.025470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1987564579, states[0] = 5.337357, states[40]= 0.004798
Saving checkpoint... 
Iteration: 2003424235, states[0] = -95.062358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2019053056, states[0] = 10.329250, states[40]= 0.005031
Saving checkpoint... 
Iteration: 2035628133, states[0] = -48.415664, states[40]= 0.000035
Saving checkpoint... 
Iteration: 2051520549, states[0] = 21.464992, states[40]= 0.009829
Saving checkpoint... 
Iteration: 2067435469, states[0] = -95.064440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2082980506, states[0] = -95.071326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2098774180, states[0] = -94.992983, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.949381
 - CaMKt in component CaMK (millimolar): 0.006765
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.490423
 - nass in component intracellular_ions (millimolar): 6.490482
 - ki in component intracellular_ions (millimolar): 145.490287
 - kss in component intracellular_ions (millimolar): 145.490268
 - cansr in component intracellular_ions (millimolar): 1.300718
 - cajsr in component intracellular_ions (millimolar): 1.263068
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003601
 - hf in component INa (dimensionless): 0.880823
 - hs in component INa (dimensionless): 0.880819
 - j in component INa (dimensionless): 0.880794
 - hsp in component INa (dimensionless): 0.727385
 - jp in component INa (dimensionless): 0.880777
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.711949
 - hLp in component INaL (dimensionless): 0.455816
 - a in component Ito (dimensionless): 0.000621
 - iF in component Ito (dimensionless): 0.999871
 - iS in component Ito (dimensionless): 0.623720
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999871
 - iSp in component Ito (dimensionless): 0.698998
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935294
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999886
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001568
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.334534
 - xs1 in component IKs (dimensionless): 0.239966
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997325
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
19:11:20 (6372): called boinc_finish(0)

</stderr_txt>
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