𝕏

Task 55335032

Name HuVeMOp_20240629201600757918_ORdGradInc_k_25-CLVPET-conf_538_1
Workunit 26275540
Created 29 Jun 2024, 18:24:19 UTC
Sent 29 Jun 2024, 21:06:37 UTC
Report deadline 2 Jul 2024, 23:59:25 UTC
Received 30 Jun 2024, 5:04:39 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 230524
Run time 2 hours 32 min 23 sec
CPU time 2 hours 26 min 59 sec
Validate state Valid
Credit 49.27
Device peak FLOPS 3.86 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.48 MB
Peak swap size 2.35 GB
Peak disk usage 0.07 MB

Stderr output

<core_client_version>7.16.21</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629201600757918_ORdGradInc_k_25-CLVPET-conf_538.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629201600757918_ORdGradInc_k_25-CLVPET-conf_538_1_r154687043_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629201600757918_ORdGradInc_k_25-CLVPET-conf_538_1_r154687043_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 92.770297
     * GNaL_b in INaL: 0.006397
     * Gto_b in Ito: 0.099327
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030061
     * GKs_b in IKs: 0.001847
     * GK1_b in IK1: 0.149948
     * Gncx_b in INaCa_i: 0.000955
     * Pnak_b in INaK: 72.138326
     * GKb_b in IKb: 0.003869
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.045726
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11383285, states[0] = -94.840945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 22791919, states[0] = -94.684859, states[40]= 0.000000
Saving checkpoint... 
Iteration: 34051122, states[0] = 17.823461, states[40]= 0.002013
Saving checkpoint... 
Iteration: 45449843, states[0] = -94.802542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 56868123, states[0] = -94.751404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 68044328, states[0] = 20.398200, states[40]= 0.001549
Saving checkpoint... 
Iteration: 79430020, states[0] = -94.786136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 90835188, states[0] = -94.712372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 102254948, states[0] = -94.557053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 113686968, states[0] = -93.529249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 125084887, states[0] = 3.008055, states[40]= 0.004216
Saving checkpoint... 
Iteration: 136614018, states[0] = -20.361626, states[40]= 0.001294
Saving checkpoint... 
Iteration: 148014280, states[0] = 27.060190, states[40]= 0.011979
Saving checkpoint... 
Iteration: 159419398, states[0] = -94.777106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 170834644, states[0] = -94.708802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 182268300, states[0] = -94.590868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 193512127, states[0] = 26.863049, states[40]= 0.024356
Saving checkpoint... 
Iteration: 204944539, states[0] = -94.787765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 216346345, states[0] = -94.721748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 227770472, states[0] = -94.595891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 239196510, states[0] = -94.271650, states[40]= 0.000000
Saving checkpoint... 
Iteration: 250599831, states[0] = -7.415656, states[40]= 0.003071
Saving checkpoint... 
Iteration: 261961283, states[0] = -94.793384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 273412022, states[0] = -94.772380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 284837314, states[0] = -94.711218, states[40]= 0.000000
Saving checkpoint... 
Iteration: 296236479, states[0] = -94.494969, states[40]= 0.000000
Saving checkpoint... 
Iteration: 307701256, states[0] = -94.334705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 319134329, states[0] = -38.548920, states[40]= 0.000478
Saving checkpoint... 
Iteration: 330555841, states[0] = 16.268268, states[40]= 0.002332
Saving checkpoint... 
Iteration: 341979860, states[0] = -94.798486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 353276719, states[0] = -94.609996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 364488272, states[0] = -94.800530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 375894787, states[0] = -94.761662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 387294587, states[0] = -94.646790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 398620261, states[0] = -25.934011, states[40]= 0.001262
Saving checkpoint... 
Iteration: 409954472, states[0] = -94.790373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 421381395, states[0] = -94.752150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 432783705, states[0] = -94.624941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 444204877, states[0] = -94.360206, states[40]= 0.000000
Saving checkpoint... 
Iteration: 455599080, states[0] = -6.783184, states[40]= 0.003203
Saving checkpoint... 
Iteration: 466825701, states[0] = -94.695777, states[40]= 0.000000
Saving checkpoint... 
Iteration: 478212941, states[0] = -94.400784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 489619480, states[0] = -25.239509, states[40]= 0.001272
Saving checkpoint... 
Iteration: 501003407, states[0] = 33.437057, states[40]= 0.440208
Saving checkpoint... 
Iteration: 512269199, states[0] = -94.591364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 523676360, states[0] = -85.620210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 535144323, states[0] = -48.070855, states[40]= 0.000133
Saving checkpoint... 
Iteration: 546362632, states[0] = -94.736166, states[40]= 0.000000
Saving checkpoint... 
Iteration: 557467209, states[0] = -94.793849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 568685510, states[0] = -93.135457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 579884280, states[0] = -94.753516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 591039122, states[0] = 22.218107, states[40]= 0.001302
Saving checkpoint... 
Iteration: 602221528, states[0] = -94.436760, states[40]= 0.000000
Saving checkpoint... 
Iteration: 613435834, states[0] = -94.782221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 624634282, states[0] = -38.504280, states[40]= 0.000480
Saving checkpoint... 
Iteration: 635874840, states[0] = -94.746098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 647069022, states[0] = 10.910523, states[40]= 0.003368
Saving checkpoint... 
Iteration: 658260852, states[0] = -94.569005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 669370676, states[0] = -94.742555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 680576079, states[0] = 7.660418, states[40]= 0.003859
Saving checkpoint... 
Iteration: 691794862, states[0] = -94.645861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 702970303, states[0] = -94.794096, states[40]= 0.000000
Saving checkpoint... 
Iteration: 714172645, states[0] = -80.158396, states[40]= 0.000001
Saving checkpoint... 
Iteration: 725358408, states[0] = -94.731421, states[40]= 0.000000
Saving checkpoint... 
Iteration: 736554462, states[0] = 16.790609, states[40]= 0.002229
Saving checkpoint... 
Iteration: 747744837, states[0] = -94.521037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 758967393, states[0] = -94.792957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 770155477, states[0] = -59.244393, states[40]= 0.000023
Saving checkpoint... 
Iteration: 781331624, states[0] = -94.701949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 792554262, states[0] = 16.865862, states[40]= 0.002214
Saving checkpoint... 
Iteration: 803757252, states[0] = -94.558335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 814953866, states[0] = -94.788254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 826014868, states[0] = 27.094068, states[40]= 0.009912
Saving checkpoint... 
Iteration: 837165177, states[0] = -69.937233, states[40]= 0.000004
Saving checkpoint... 
Iteration: 848218429, states[0] = -94.422778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 859389734, states[0] = -94.756025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 870592905, states[0] = -2.041440, states[40]= 0.003996
Saving checkpoint... 
Iteration: 881737085, states[0] = -94.494299, states[40]= 0.000000
Saving checkpoint... 
Iteration: 892885942, states[0] = -94.753229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 904061746, states[0] = 13.959618, states[40]= 0.002794
Saving checkpoint... 
Iteration: 915267577, states[0] = -94.585394, states[40]= 0.000000
Saving checkpoint... 
Iteration: 926344684, states[0] = -94.716538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 937521671, states[0] = 26.707325, states[40]= 0.001644
Saving checkpoint... 
Iteration: 948703752, states[0] = -94.350620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 959867383, states[0] = -94.738402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 971033656, states[0] = 23.931456, states[40]= 0.001091
Saving checkpoint... 
Iteration: 982122282, states[0] = -27.725607, states[40]= 0.001208
Saving checkpoint... 
Iteration: 993336058, states[0] = -94.706373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1004543284, states[0] = 20.818078, states[40]= 0.001508
Saving checkpoint... 
Iteration: 1015796728, states[0] = -94.647772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1026985872, states[0] = -94.796820, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1038143394, states[0] = -47.157129, states[40]= 0.000152
Saving checkpoint... 
Iteration: 1049364078, states[0] = -94.735089, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1060541782, states[0] = 21.331169, states[40]= 0.001430
Saving checkpoint... 
Iteration: 1071726008, states[0] = -94.452375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1082935042, states[0] = -94.779674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1094142404, states[0] = -46.190640, states[40]= 0.000175
Saving checkpoint... 
Iteration: 1105350205, states[0] = -94.721542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1116469898, states[0] = -94.792030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1127654636, states[0] = -58.381165, states[40]= 0.000027
Saving checkpoint... 
Iteration: 1138718141, states[0] = -94.420178, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1149894397, states[0] = -94.757761, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1161077040, states[0] = 7.190854, states[40]= 0.003916
Saving checkpoint... 
Iteration: 1172265923, states[0] = -94.579961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1183482204, states[0] = -94.795146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1194785213, states[0] = -94.624483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1206153714, states[0] = -57.442390, states[40]= 0.000031
Saving checkpoint... 
Iteration: 1217556741, states[0] = 15.925838, states[40]= 0.002401
Saving checkpoint... 
Iteration: 1228953759, states[0] = -94.786268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1240100757, states[0] = -8.204305, states[40]= 0.002905
Saving checkpoint... 
Iteration: 1251496290, states[0] = -94.798233, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1262794170, states[0] = -94.641859, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1274178716, states[0] = -88.581835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1285564480, states[0] = 12.844267, states[40]= 0.003013
Saving checkpoint... 
Iteration: 1296762151, states[0] = -94.569473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1308164666, states[0] = -69.312475, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1319516378, states[0] = 27.121861, states[40]= 0.006181
Saving checkpoint... 
Iteration: 1330886605, states[0] = -94.751634, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1342294943, states[0] = -94.642930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1353656460, states[0] = -60.254099, states[40]= 0.000020
Saving checkpoint... 
Iteration: 1364980704, states[0] = -94.793898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1376356795, states[0] = -94.726814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1387726226, states[0] = -94.451715, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1399148508, states[0] = -52.211645, states[40]= 0.000072
Saving checkpoint... 
Iteration: 1410531594, states[0] = 24.525796, states[40]= 0.001035
Saving checkpoint... 
Iteration: 1421848385, states[0] = -94.718157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1433232778, states[0] = -94.476244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1444600127, states[0] = -7.662645, states[40]= 0.003020
Saving checkpoint... 
Iteration: 1455862436, states[0] = -94.731698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1467234125, states[0] = -94.480977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1478608869, states[0] = -15.582101, states[40]= 0.001600
Saving checkpoint... 
Iteration: 1489988600, states[0] = -94.795316, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1501318238, states[0] = -79.565119, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1512548655, states[0] = 15.338190, states[40]= 0.002895
Saving checkpoint... 
Iteration: 1523625607, states[0] = -94.721733, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1534770788, states[0] = 26.554299, states[40]= 0.001666
Saving checkpoint... 
Iteration: 1545923066, states[0] = -94.676532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1557024676, states[0] = 25.617049, states[40]= 0.000947
Saving checkpoint... 
Iteration: 1568070489, states[0] = 12.944908, states[40]= 0.002928
Saving checkpoint... 
Iteration: 1579128760, states[0] = -22.930101, states[40]= 0.001430
Saving checkpoint... 
Iteration: 1590151595, states[0] = -94.435709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1601070816, states[0] = 14.236784, states[40]= 0.003044
Saving checkpoint... 
Iteration: 1612065469, states[0] = -94.402887, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1622805424, states[0] = -94.111623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1633807881, states[0] = -94.321366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1644795231, states[0] = -94.301200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1655803889, states[0] = -94.315838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1666786900, states[0] = -94.294063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1677803423, states[0] = -94.073068, states[40]= 0.000000
Total time: 3360000.000000
State Variables:
 - v in component membrane (millivolt): -94.160064
 - CaMKt in component CaMK (millimolar): 0.001141
 - cass in component intracellular_ions (millimolar): 0.000087
 - nai in component intracellular_ions (millimolar): 6.318656
 - nass in component intracellular_ions (millimolar): 6.318742
 - ki in component intracellular_ions (millimolar): 145.570807
 - kss in component intracellular_ions (millimolar): 145.570796
 - cansr in component intracellular_ions (millimolar): 1.569719
 - cajsr in component intracellular_ions (millimolar): 1.569800
 - cai in component intracellular_ions (millimolar): 0.000090
 - m in component INa (dimensionless): 0.003900
 - hf in component INa (dimensionless): 0.866520
 - hs in component INa (dimensionless): 0.866521
 - j in component INa (dimensionless): 0.866522
 - hsp in component INa (dimensionless): 0.700947
 - jp in component INa (dimensionless): 0.866523
 - mL in component INaL (dimensionless): 0.000057
 - hL in component INaL (dimensionless): 0.709176
 - hLp in component INaL (dimensionless): 0.515771
 - a in component Ito (dimensionless): 0.000655
 - iF in component Ito (dimensionless): 0.999852
 - iS in component Ito (dimensionless): 0.997656
 - ap in component Ito (dimensionless): 0.000334
 - iFp in component Ito (dimensionless): 0.999852
 - iSp in component Ito (dimensionless): 0.999211
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998803
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003017
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.001889
 - xs1 in component IKs (dimensionless): 0.023876
 - xs2 in component IKs (dimensionless): 0.000095
 - xk1 in component IK1 (dimensionless): 0.997525
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
20:59:09 (82888): called boinc_finish(0)

</stderr_txt>
]]>


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